Eosinofilia asociada a carcinoma pulmonar. Estudio clinico de 6 casos
Eosinophylia in association with cancer of the lung
H. Verea Hernando, M.T. Martin Egaña, J. Masa Jimenez, L. Dominguez Juncal, J. Fontan Bueso
Sección de Neumología. C.S. Juan Canalejo. La Coruña
Read
5580
Timeswas read the article
3619
Total PDF
1961
Total HTML
Share statistics
array:23 [ "pii" => "S0300289615320950" "issn" => "03002896" "doi" => "10.1016/S0300-2896(15)32095-0" "estado" => "S300" "fechaPublicacion" => "1985-11-01" "aid" => "72165" "copyright" => "Sociedad Española de Neumología y Cirugía Torácica" "copyrightAnyo" => "1985" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Arch Bronconeumol. 1985;21:266-8" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 1931 "formatos" => array:3 [ "EPUB" => 69 "HTML" => 673 "PDF" => 1189 ] ] "itemSiguiente" => array:18 [ "pii" => "S0300289615320962" "issn" => "03002896" "doi" => "10.1016/S0300-2896(15)32096-2" "estado" => "S300" "fechaPublicacion" => "1985-11-01" "aid" => "72166" "copyright" => "Sociedad Española de Neumología y Cirugía Torácica" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Arch Bronconeumol. 1985;21:269-72" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 11947 "formatos" => array:3 [ "EPUB" => 61 "HTML" => 2901 "PDF" => 8985 ] ] "es" => array:10 [ "idiomaDefecto" => true "titulo" => "Obstruccion bronquial por inhalacion de agua destilada" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "269" "paginaFinal" => "272" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Bronchial obstruction due to inhalation of destilled water" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "J. Perez Neria, H. Ocaña Servin, A. Rojas Gonzalez, H. Rubio Monteverde, G. Carrillo Rodriguez, M. Selman Lama" "autores" => array:6 [ 0 => array:2 [ "nombre" => "J." "apellidos" => "Perez Neria" ] 1 => array:2 [ "nombre" => "H." "apellidos" => "Ocaña Servin" ] 2 => array:2 [ "nombre" => "A." "apellidos" => "Rojas Gonzalez" ] 3 => array:2 [ "nombre" => "H." "apellidos" => "Rubio Monteverde" ] 4 => array:2 [ "nombre" => "G." "apellidos" => "Carrillo Rodriguez" ] 5 => array:2 [ "nombre" => "M." "apellidos" => "Selman Lama" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615320962?idApp=UINPBA00003Z" "url" => "/03002896/0000002100000006/v1_201509151106/S0300289615320962/v1_201509151106/es/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S0300289615320949" "issn" => "03002896" "doi" => "10.1016/S0300-2896(15)32094-9" "estado" => "S300" "fechaPublicacion" => "1985-11-01" "aid" => "72164" "copyright" => "Sociedad Española de Neumología y Cirugía Torácica" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Arch Bronconeumol. 1985;21:262-5" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 1247 "formatos" => array:3 [ "EPUB" => 46 "HTML" => 619 "PDF" => 582 ] ] "es" => array:10 [ "idiomaDefecto" => true "titulo" => "Mesotelioma pleural: a proposito de siete casos" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "262" "paginaFinal" => "265" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Pleural mesothelioma: seven cases" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "J. Oron Alpuente, A. Caballero Garate, J. Cortes Almiñana, C. Carbonell Antoli" "autores" => array:4 [ 0 => array:2 [ "nombre" => "J." "apellidos" => "Oron Alpuente" ] 1 => array:2 [ "nombre" => "A." "apellidos" => "Caballero Garate" ] 2 => array:2 [ "nombre" => "J." "apellidos" => "Cortes Almiñana" ] 3 => array:2 [ "nombre" => "C." "apellidos" => "Carbonell Antoli" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615320949?idApp=UINPBA00003Z" "url" => "/03002896/0000002100000006/v1_201509151106/S0300289615320949/v1_201509151106/es/main.assets" ] "es" => array:13 [ "idiomaDefecto" => true "titulo" => "Eosinofilia asociada a carcinoma pulmonar. Estudio clinico de 6 casos" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "266" "paginaFinal" => "268" ] ] "autores" => array:1 [ 0 => array:3 [ "autoresLista" => "H. Verea Hernando, M.T. Martin Egaña, J. Masa Jimenez, L. Dominguez Juncal, J. Fontan Bueso" "autores" => array:5 [ 0 => array:2 [ "nombre" => "H." "apellidos" => "Verea Hernando" ] 1 => array:2 [ "nombre" => "M.T." "apellidos" => "Martin Egaña" ] 2 => array:2 [ "nombre" => "J." "apellidos" => "Masa Jimenez" ] 3 => array:2 [ "nombre" => "L." "apellidos" => "Dominguez Juncal" ] 4 => array:2 [ "nombre" => "J." "apellidos" => "Fontan Bueso" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Sección de Neumología. C.S. Juan Canalejo. La Coruña" "identificador" => "aff0005" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Eosinophylia in association with cancer of the lung" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "1985-01-21" "fechaAceptado" => "1985-04-13" "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Presentamos seis pacientes diagnosticados de carcinoma pulmonar (cuatro epidermoides, un indiferenciado de células grandes y un <span class="elsevierStyleItalic">oat-cell</span>) que cursaban con eosinofilia periférica (EP) entre 1.440 y 15.964/μl). En tres casos no se detectaron datos bioquímicos ni gammagráficos que sugiriesen metástasis. Aunque en tres pacientes la EP remitió con el tratamiento, en uno no se elevó significativamente con la recurrencia del proceso. La evolución fue más tórpida en los que tenian EP más elevada. Aunque, en ocasiones, puede facilitar la aparición de tromboembolias, su interés es de limitado valor en el manejo de la enfermedad de base.</p></span>" ] "en" => array:1 [ "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">The authors report seven patients with pulmonar) cancer (4 epidermoid, 1 undifferentiated giant cell and 1 oat cell) who presented peripherical eosinophylia (PE) between 1.440-15.964/ml. In 3 cases no biochemical nor gammagraphic data suggesting metastasis were found. Although in 3 of the patients the PE remitted with treatment, in another one recurrence of the process did not result in any significant elevation. Patients with the highest EP showed the slowest course. Although on certain occasions, PE may favour thromboembolisms, its presence in the particular patients is of limited value only.</p></span>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:24 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Eosinophilia" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "P.F. Weller" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Allergy Clin Immunol" "fecha" => "1984" "volumen" => "73" "paginaInicial" => "1" "paginaFinal" => "10" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6693661" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Hematology" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "W.J. Williams" 1 => "E. Bentler" 2 => "A. Erslen" 3 => "M.A. Lichtman" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:4 [ "edicion" => "5 ed" "fecha" => "1983" "editorial" => "Mac Graw Hill" "editorialLocalizacion" => "New York" ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Tumour-associated eosinophilia: a review" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "D. Lowe" 1 => "J. Jorizzo" 2 => "M.S.R. Hutt" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Clin Pathol" "fecha" => "1981" "volumen" => "34" "paginaInicial" => "1343" "paginaFinal" => "1348" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7035499" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Eosinophilia in malignant tumors: its significance" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "N.H. Isaacson" 1 => "P. Rapaport" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Ann Intern Med" "fecha" => "1946" "volumen" => "25" "paginaInicial" => "893" "paginaFinal" => "902" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20277495" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "5." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Eosinofilia pulmonar. Introducción y clasificación. XII Congreso de la Sociedad Española de Alergia e Inmunología Clínica" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "F. Lahoz" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "En: Allergol Immunopathol (Madrid)" "fecha" => "1980" "volumen" => "7" "paginaInicial" => "39" "paginaFinal" => "40" ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0030" "etiqueta" => "6." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cancer and eosinophilia (Editorial)" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "P.B. Beeson" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1056/NEJM198309293091310" "Revista" => array:6 [ "tituloSerie" => "N Engl J Med" "fecha" => "1983" "volumen" => "309" "paginaInicial" => "792" "paginaFinal" => "793" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6888457" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0035" "etiqueta" => "7." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Hyperosinophilie au cours des cancers et des cirrhoses: M. térêt du compte absolu des eosinophiles" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "C. Noirot" 1 => "F. Leynadier" 2 => "H. Luce" 3 => "N. Abuaf" 4 => "Bernard PhF" 5 => "J. Dry" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Sem Hosp Paris" "fecha" => "1982" "volumen" => "58" "paginaInicial" => "133" "paginaFinal" => "137" ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib0040" "etiqueta" => "8." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Eosinophilia in bronchogenic carcinoma (Letter)" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "T.M. Healy" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "N Engl J Med" "fecha" => "1974" "volumen" => "291" "paginaInicial" => "794" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4414213" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib0045" "etiqueta" => "9." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Eosinophilia in bronchogenic carcinoma (Letter)" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "A.L. Dellon" 1 => "R.B. Hume" 2 => "P.B. Chretien" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "N Engl J Med" "fecha" => "1974" "volumen" => "291" "paginaInicial" => "207" "paginaFinal" => "208" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4834493" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib0050" "etiqueta" => "10." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Radiation-related eosinophilia" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "N.A. Ghossein" 1 => "J.L. Bosworth" 2 => "P. Stacey" 3 => "F.M. Muggia" 4 => "V. Krishnaswamy" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1148/117.2.413" "Revista" => array:6 [ "tituloSerie" => "Radiology" "fecha" => "1975" "volumen" => "117" "paginaInicial" => "413" "paginaFinal" => "417" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1178876" "web" => "Medline" ] ] ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib0055" "etiqueta" => "11." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Tumor associated eosinophilotactic factor" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "S.I. Wasserman" 1 => "E.J. Goetzl" 2 => "L. Ellman" 3 => "K.F. Ansten" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1056/NEJM197402212900802" "Revista" => array:6 [ "tituloSerie" => "N Engl J Med" "fecha" => "1974" "volumen" => "290" "paginaInicial" => "420" "paginaFinal" => "424" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4811016" "web" => "Medline" ] ] ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib0060" "etiqueta" => "12." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Production of a low molecular weight eosinophil polimorphonuclear leukocyte chemotactic factor by anaplastic squamous cellcarcinomas of human lung" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "E.J. Goetzl" 1 => "A.H. Tashjian" 2 => "R.H. Rubin" 3 => "F. Ansten" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1172/JCI108991" "Revista" => array:6 [ "tituloSerie" => "J Clin Invest" "fecha" => "1978" "volumen" => "61" "paginaInicial" => "770" "paginaFinal" => "780" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/641154" "web" => "Medline" ] ] ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib0065" "etiqueta" => "13." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pulmonary carcinoma with eosinophilia" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "A. Slungaard" 1 => "J. Ascensao" 2 => "E. Zangani" 3 => "H. Jacols" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1056/NEJM198309293091307" "Revista" => array:6 [ "tituloSerie" => "N Engl J Med" "fecha" => "1983" "volumen" => "309" "paginaInicial" => "778" "paginaFinal" => "781" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6310397" "web" => "Medline" ] ] ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib0070" "etiqueta" => "14." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Eosinophilia: an unusual presentaron of carcinoma of the lung" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "R.S. Ramaiah" 1 => "R.W. Biagi" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Practicioner" "fecha" => "1982" "volumen" => "226" "paginaInicial" => "1805" "paginaFinal" => "1806" ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib0075" "etiqueta" => "15." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Bronchial carcinoma with eosinophilia and cardiomegaly" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "A.J. Barrett" 1 => "A. Barret" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Brit J Dis Chest" "fecha" => "1975" "volumen" => "69" "paginaInicial" => "287" "paginaFinal" => "292" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/128374" "web" => "Medline" ] ] ] ] ] ] ] ] 15 => array:3 [ "identificador" => "bib0080" "etiqueta" => "16." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Unusual leukocyte responses in primary carcinoma of the lung" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "R.J. Fahey" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Cancer" "fecha" => "1951" "volumen" => "4" "paginaInicial" => "930" "paginaFinal" => "935" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14879357" "web" => "Medline" ] ] ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bib0085" "etiqueta" => "17." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The fine structure of large cell indifferentiated carcinoma of the lung: evidence for its relation to squamous cell carcinomas and adenocarcinomas" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "A. Churg" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Human Pathol" "fecha" => "1978" "volumen" => "9" "paginaInicial" => "143" "paginaFinal" => "156" ] ] ] ] ] ] 17 => array:3 [ "identificador" => "bib0090" "etiqueta" => "18." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Regulation of reaginic antibody formation in animals" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "T. Tada" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Prog Allergy" "fecha" => "1975" "volumen" => "19" "paginaInicial" => "122" "paginaFinal" => "127" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/56008" "web" => "Medline" ] ] ] ] ] ] ] ] 18 => array:3 [ "identificador" => "bib0095" "etiqueta" => "19." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Mechanism of eosinophilia II. Role of the lymphocite" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "A. Basten" 1 => "P. Beeson" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "J Exp Med" "fecha" => "1970" "paginaInicial" => "1288" "paginaFinal" => "1305" ] ] ] ] ] ] 19 => array:3 [ "identificador" => "bib0100" "etiqueta" => "20." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Studies on interrelations between eosinophilia, serum IgE and tissue mast cells" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "T. Takenaka" 1 => "M. Okuda" 2 => "K. Kubo" 3 => "H. Uda" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin Allergy" "fecha" => "1975" "volumen" => "5" "paginaInicial" => "175" "paginaFinal" => "180" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/806397" "web" => "Medline" ] ] ] ] ] ] ] ] 20 => array:3 [ "identificador" => "bib0105" "etiqueta" => "21." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Elevated serum immunoglobulin E in bronchial carcinoma: its relation to the histology and prognosis of the cancer" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "B. Hallgren" 1 => "H. Arrendal" 2 => "K. Hiesche" 3 => "G. Lundquist" 4 => "E. Nöu" 5 => "O. Zetterström" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Allergy Clin Immunol" "fecha" => "1981" "volumen" => "67" "paginaInicial" => "398" "paginaFinal" => "406" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6164710" "web" => "Medline" ] ] ] ] ] ] ] ] 21 => array:3 [ "identificador" => "bib0110" "etiqueta" => "22." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The pathogenesis of Loeffler's endomyocardial disease and its relationship to endomyocardio Fibrosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "E.G.J. Olsen" 1 => "C.J.F. Spry" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Progres Cardiol" "fecha" => "1979" "volumen" => "8" "paginaInicial" => "281" "paginaFinal" => "303" ] ] ] ] ] ] 22 => array:3 [ "identificador" => "bib0115" "etiqueta" => "23." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The idopathic hipereosinophilia syndrome. Clinical pathophysiologic and therapeutic considerations" "autores" => array:1 [ 0 => array:3 [ "colaboracion" => "(Moderador)" "etal" => false "autores" => array:1 [ 0 => "A.S. Fauci" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Ann Intern Med" "fecha" => "1982" "volumen" => "97" "paginaInicial" => "78" "paginaFinal" => "92" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7046556" "web" => "Medline" ] ] ] ] ] ] ] ] 23 => array:3 [ "identificador" => "bib0120" "etiqueta" => "24." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cytotoxic effects of the guinea pig eosinophil major basic protein on tracheal epithelium" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "E. Frigas" 1 => "D.A. Loegerin" 2 => "G.G. Gleich" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Lab Invest" "fecha" => "1980" "volumen" => "42" "paginaInicial" => "35" "paginaFinal" => "43" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7351830" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "es" "url" => "/03002896/0000002100000006/v1_201509151106/S0300289615320950/v1_201509151106/es/main.assets" "Apartado" => array:4 [ "identificador" => "9277" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Originales" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/03002896/0000002100000006/v1_201509151106/S0300289615320950/v1_201509151106/es/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615320950?idApp=UINPBA00003Z" ]
| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 9 | 21 | 30 |
| 2024 October | 54 | 60 | 114 |
| 2024 September | 46 | 58 | 104 |
| 2024 August | 61 | 67 | 128 |
| 2024 July | 42 | 67 | 109 |
| 2024 June | 60 | 51 | 111 |
| 2024 May | 59 | 53 | 112 |
| 2024 April | 62 | 54 | 116 |
| 2024 March | 51 | 42 | 93 |
| 2024 February | 36 | 59 | 95 |
| 2024 January | 0 | 23 | 23 |
| 2023 December | 0 | 37 | 37 |
| 2023 November | 0 | 11 | 11 |
| 2023 October | 0 | 11 | 11 |
| 2023 September | 0 | 4 | 4 |
| 2023 August | 0 | 7 | 7 |
| 2023 July | 0 | 12 | 12 |
| 2023 June | 0 | 2 | 2 |
| 2023 April | 0 | 1 | 1 |
| 2023 March | 8 | 5 | 13 |
| 2023 February | 46 | 36 | 82 |
| 2023 January | 36 | 41 | 77 |
| 2022 December | 30 | 42 | 72 |
| 2022 November | 48 | 53 | 101 |
| 2022 October | 41 | 66 | 107 |
| 2022 September | 33 | 57 | 90 |
| 2022 August | 36 | 91 | 127 |
| 2022 July | 23 | 37 | 60 |
| 2022 June | 25 | 48 | 73 |
| 2022 May | 24 | 62 | 86 |
| 2022 April | 20 | 50 | 70 |
| 2022 March | 29 | 57 | 86 |
| 2022 February | 20 | 55 | 75 |
| 2022 January | 28 | 62 | 90 |
| 2021 December | 12 | 65 | 77 |
| 2021 November | 15 | 51 | 66 |
| 2021 October | 14 | 52 | 66 |
| 2021 September | 15 | 34 | 49 |
| 2021 August | 16 | 49 | 65 |
| 2021 July | 20 | 50 | 70 |
| 2021 June | 17 | 67 | 84 |
| 2021 May | 11 | 51 | 62 |
| 2021 April | 16 | 89 | 105 |
| 2021 March | 36 | 51 | 87 |
| 2021 February | 32 | 35 | 67 |
| 2021 January | 24 | 45 | 69 |
| 2020 December | 20 | 48 | 68 |
| 2020 November | 10 | 53 | 63 |
| 2020 October | 13 | 36 | 49 |
| 2020 September | 8 | 30 | 38 |
| 2020 August | 17 | 38 | 55 |
| 2020 July | 21 | 52 | 73 |
| 2020 June | 8 | 36 | 44 |
| 2020 May | 5 | 24 | 29 |
| 2020 April | 15 | 17 | 32 |
| 2020 March | 9 | 36 | 45 |
| 2020 February | 22 | 44 | 66 |
| 2020 January | 18 | 26 | 44 |
| 2019 December | 30 | 42 | 72 |
| 2019 November | 17 | 29 | 46 |
| 2019 October | 8 | 52 | 60 |
| 2019 September | 31 | 71 | 102 |
| 2019 August | 26 | 30 | 56 |
| 2019 July | 5 | 47 | 52 |
| 2019 June | 11 | 65 | 76 |
| 2019 May | 16 | 54 | 70 |
| 2019 April | 31 | 70 | 101 |
| 2019 March | 5 | 25 | 30 |
| 2019 February | 6 | 28 | 34 |
| 2019 January | 6 | 36 | 42 |
| 2018 December | 5 | 38 | 43 |
| 2018 November | 22 | 36 | 58 |
| 2018 October | 21 | 24 | 45 |
| 2018 September | 10 | 14 | 24 |
| 2018 May | 4 | 1 | 5 |
| 2018 April | 11 | 7 | 18 |
| 2018 March | 6 | 6 | 12 |
| 2018 February | 5 | 8 | 13 |
| 2018 January | 7 | 7 | 14 |
| 2017 December | 6 | 20 | 26 |
| 2017 November | 13 | 20 | 33 |
| 2017 October | 13 | 24 | 37 |
| 2017 September | 5 | 20 | 25 |
| 2017 August | 15 | 23 | 38 |
| 2017 July | 8 | 27 | 35 |
| 2017 June | 10 | 36 | 46 |
| 2017 May | 11 | 26 | 37 |
| 2017 April | 8 | 17 | 25 |
| 2017 March | 10 | 25 | 35 |
| 2017 February | 5 | 17 | 22 |
| 2017 January | 3 | 10 | 13 |
| 2016 December | 7 | 10 | 17 |
| 2016 November | 16 | 21 | 37 |
| 2016 October | 23 | 21 | 44 |
| 2016 September | 22 | 51 | 73 |
| 2016 August | 25 | 16 | 41 |
| 2016 July | 19 | 6 | 25 |
| 2016 June | 22 | 15 | 37 |
| 2016 May | 24 | 11 | 35 |
| 2016 April | 3 | 0 | 3 |
| 2016 March | 12 | 0 | 12 |
| 2016 February | 11 | 0 | 11 |
| 2016 January | 18 | 14 | 32 |
| 2015 December | 19 | 12 | 31 |
| 2015 November | 24 | 5 | 29 |
| 2015 October | 4 | 1 | 5 |
| 2015 September | 1 | 0 | 1 |
Show all
