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        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">El n&#250;mero de pacientes con intoxicaci&#243;n aguda por opi&#225;ceos se ha incrementado de modo importante durante los &#250;ltimos a&#241;os en nuestro pa&#237;s&#46; De 34 pacientes con sobredosis de hero&#237;na&#44; 11 presentaron edema agudo de pulm&#243;n&#44; 8 de los cuales precisaron ventilaci&#243;n mec&#225;nica&#46; Se constat&#243; ingesta simult&#225;nea de otro agente en 6 casos&#46; Se determinaron los niveles sangu&#237;neos y urinarios del opi&#225;ceo&#46; Se efectuaron determinaciones hemodin&#225;micas y monitorizaci&#243;n de la funci&#243;n respiratoria&#44; diagnostic&#225;ndose edema pulmonar no cardiog&#233;nico&#46; Adem&#225;s se evalu&#243; el grado y severidad de las complicaciones cardiacas&#44; neurol&#243;gicas y s&#233;pticas&#46; Se ha establecido la eficacia de naloxona como el antagonista opi&#225;ceo id&#243;neo asi como otras medidas terap&#233;uticas &#40;intubaci&#243;n&#44; ventilaci&#243;n mec&#225;nica&#44; PEEP&#41;&#46; Los resultados del tratamiento han sido satisfactorios&#44; con curaci&#243;n de todos los pacientes estudiados&#46; Finalmente se han revisado las diferentes teor&#237;as etiopatog&#233;nicas relacionadas con el &#171;pulm&#243;n de hero&#237;na&#187;&#46; Se concluye poniendo de manifiesto la elevada incidencia de esta grave complicaci&#243;n pulmonar y la eficacia del tratamiento correcto&#46;</p></span>"
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        "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">There has been a considerable increase in patients with acute drug overdose in our country over recent years&#46;</p><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Out of 34 patients who presented with the effects of heroin overdose&#44; 11 had acute pulmonary edema with mechanical ventilation necessary for eight of these&#46;</p><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">In 6 cases simultaneous ingestion of other substances was discovered&#46; Plasmatic and urinary levels of the drug were determined and hemodynamic studies performed&#59; respiratory function was monitored and a diagnosis of pulmonary edema of non-cardiogenic origin established&#46;</p><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">The degree and severity of cardiac&#44; neurologic and septic complications were evaluated&#46; Naloxone proved the preferred opium antagonist together with other therapeutic measures such as intubation&#44; mechanical ventilation and PEEP&#46;</p><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">The results of the treatment were satisfactory with all patients in the study being cured&#46;</p><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">The high incidence of this severe pulmonary complication and the efficacy of the correct therapy are emphasized&#46;</p></span>"
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Journal Information
Vol. 20. Issue 6.
Pages 234-238 (November - December 1984)
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Vol. 20. Issue 6.
Pages 234-238 (November - December 1984)
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Edema pulmonar por sobredosis de heroina
Pulmonary edema due to heroin overdose
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V. Cerdeño Impuesto, J.A. Garcia Garcia, R. Denia Lafuente, A. Garcia De Lorenzo, A. Aguado Matorras
Servicio de Medicina Intensiva. C.S.S.S. La Paz. Madrid
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El número de pacientes con intoxicación aguda por opiáceos se ha incrementado de modo importante durante los últimos años en nuestro país. De 34 pacientes con sobredosis de heroína, 11 presentaron edema agudo de pulmón, 8 de los cuales precisaron ventilación mecánica. Se constató ingesta simultánea de otro agente en 6 casos. Se determinaron los niveles sanguíneos y urinarios del opiáceo. Se efectuaron determinaciones hemodinámicas y monitorización de la función respiratoria, diagnosticándose edema pulmonar no cardiogénico. Además se evaluó el grado y severidad de las complicaciones cardiacas, neurológicas y sépticas. Se ha establecido la eficacia de naloxona como el antagonista opiáceo idóneo asi como otras medidas terapéuticas (intubación, ventilación mecánica, PEEP). Los resultados del tratamiento han sido satisfactorios, con curación de todos los pacientes estudiados. Finalmente se han revisado las diferentes teorías etiopatogénicas relacionadas con el «pulmón de heroína». Se concluye poniendo de manifiesto la elevada incidencia de esta grave complicación pulmonar y la eficacia del tratamiento correcto.

There has been a considerable increase in patients with acute drug overdose in our country over recent years.

Out of 34 patients who presented with the effects of heroin overdose, 11 had acute pulmonary edema with mechanical ventilation necessary for eight of these.

In 6 cases simultaneous ingestion of other substances was discovered. Plasmatic and urinary levels of the drug were determined and hemodynamic studies performed; respiratory function was monitored and a diagnosis of pulmonary edema of non-cardiogenic origin established.

The degree and severity of cardiac, neurologic and septic complications were evaluated. Naloxone proved the preferred opium antagonist together with other therapeutic measures such as intubation, mechanical ventilation and PEEP.

The results of the treatment were satisfactory with all patients in the study being cured.

The high incidence of this severe pulmonary complication and the efficacy of the correct therapy are emphasized.

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Copyright © 1984. Sociedad Española de Neumología y Cirugía Torácica
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