Edema pulmonar por sobredosis de heroina
Pulmonary edema due to heroin overdose
V. Cerdeño Impuesto, J.A. Garcia Garcia, R. Denia Lafuente, A. Garcia De Lorenzo, A. Aguado Matorras
Servicio de Medicina Intensiva. C.S.S.S. La Paz. Madrid
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Carbajo, F.J. Ortega Morales, M. Hernandez, W. Torre" "autores" => array:4 [ 0 => array:2 [ "nombre" => "M." "apellidos" => "Carbajo" ] 1 => array:2 [ "nombre" => "F.J." "apellidos" => "Ortega Morales" ] 2 => array:2 [ "nombre" => "M." "apellidos" => "Hernandez" ] 3 => array:2 [ "nombre" => "W." "apellidos" => "Torre" ] ] ] 1 => array:2 [ "autoresLista" => "R. Ondiviela" "autores" => array:1 [ 0 => array:2 [ "nombre" => "R." "apellidos" => "Ondiviela" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615322171?idApp=UINPBA00003Z" "url" => "/03002896/0000002000000006/v1_201509151135/S0300289615322171/v1_201509151135/es/main.assets" ] "es" => array:13 [ "idiomaDefecto" => true "titulo" => "Edema pulmonar por sobredosis de heroina" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "234" "paginaFinal" => "238" ] ] "autores" => array:1 [ 0 => array:3 [ "autoresLista" => "V. Cerdeño Impuesto, J.A. Garcia Garcia, R. Denia Lafuente, A. Garcia De Lorenzo, A. Aguado Matorras" "autores" => array:5 [ 0 => array:2 [ "nombre" => "V." "apellidos" => "Cerdeño Impuesto" ] 1 => array:2 [ "nombre" => "J.A." "apellidos" => "Garcia Garcia" ] 2 => array:2 [ "nombre" => "R." "apellidos" => "Denia Lafuente" ] 3 => array:2 [ "nombre" => "A." "apellidos" => "Garcia De Lorenzo" ] 4 => array:2 [ "nombre" => "A." "apellidos" => "Aguado Matorras" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Servicio de Medicina Intensiva. C.S.S.S. La Paz. Madrid" "identificador" => "aff0005" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Pulmonary edema due to heroin overdose" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "1984-01-25" "fechaAceptado" => "1984-03-24" "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">El número de pacientes con intoxicación aguda por opiáceos se ha incrementado de modo importante durante los últimos años en nuestro país. De 34 pacientes con sobredosis de heroína, 11 presentaron edema agudo de pulmón, 8 de los cuales precisaron ventilación mecánica. Se constató ingesta simultánea de otro agente en 6 casos. Se determinaron los niveles sanguíneos y urinarios del opiáceo. Se efectuaron determinaciones hemodinámicas y monitorización de la función respiratoria, diagnosticándose edema pulmonar no cardiogénico. Además se evaluó el grado y severidad de las complicaciones cardiacas, neurológicas y sépticas. Se ha establecido la eficacia de naloxona como el antagonista opiáceo idóneo asi como otras medidas terapéuticas (intubación, ventilación mecánica, PEEP). Los resultados del tratamiento han sido satisfactorios, con curación de todos los pacientes estudiados. Finalmente se han revisado las diferentes teorías etiopatogénicas relacionadas con el «pulmón de heroína». Se concluye poniendo de manifiesto la elevada incidencia de esta grave complicación pulmonar y la eficacia del tratamiento correcto.</p></span>" ] "en" => array:1 [ "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">There has been a considerable increase in patients with acute drug overdose in our country over recent years.</p><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Out of 34 patients who presented with the effects of heroin overdose, 11 had acute pulmonary edema with mechanical ventilation necessary for eight of these.</p><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">In 6 cases simultaneous ingestion of other substances was discovered. Plasmatic and urinary levels of the drug were determined and hemodynamic studies performed; respiratory function was monitored and a diagnosis of pulmonary edema of non-cardiogenic origin established.</p><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">The degree and severity of cardiac, neurologic and septic complications were evaluated. Naloxone proved the preferred opium antagonist together with other therapeutic measures such as intubation, mechanical ventilation and PEEP.</p><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">The results of the treatment were satisfactory with all patients in the study being cured.</p><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">The high incidence of this severe pulmonary complication and the efficacy of the correct therapy are emphasized.</p></span>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografia" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:19 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Edema of left lung-morphia poisoning" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "W. 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| 2023 December | 0 | 24 | 24 |
| 2023 November | 0 | 47 | 47 |
| 2023 October | 0 | 45 | 45 |
| 2023 September | 0 | 34 | 34 |
| 2023 August | 0 | 13 | 13 |
| 2023 July | 0 | 17 | 17 |
| 2023 June | 0 | 2 | 2 |
| 2023 April | 0 | 5 | 5 |
| 2023 March | 13 | 9 | 22 |
| 2023 February | 70 | 27 | 97 |
| 2023 January | 66 | 33 | 99 |
| 2022 December | 56 | 29 | 85 |
| 2022 November | 104 | 38 | 142 |
| 2022 October | 98 | 55 | 153 |
| 2022 September | 85 | 39 | 124 |
| 2022 August | 66 | 38 | 104 |
| 2022 July | 60 | 46 | 106 |
| 2022 June | 74 | 38 | 112 |
| 2022 May | 84 | 45 | 129 |
| 2022 April | 69 | 42 | 111 |
| 2022 March | 92 | 53 | 145 |
| 2022 February | 61 | 45 | 106 |
| 2022 January | 95 | 71 | 166 |
| 2021 December | 107 | 99 | 206 |
| 2021 November | 75 | 57 | 132 |
| 2021 October | 62 | 75 | 137 |
| 2021 September | 52 | 72 | 124 |
| 2021 August | 40 | 61 | 101 |
| 2021 July | 55 | 62 | 117 |
| 2021 June | 89 | 93 | 182 |
| 2021 May | 86 | 115 | 201 |
| 2021 April | 157 | 139 | 296 |
| 2021 March | 101 | 129 | 230 |
| 2021 February | 94 | 87 | 181 |
| 2021 January | 68 | 99 | 167 |
| 2020 December | 56 | 93 | 149 |
| 2020 November | 68 | 133 | 201 |
| 2020 October | 56 | 62 | 118 |
| 2020 September | 69 | 72 | 141 |
| 2020 August | 54 | 75 | 129 |
| 2020 July | 74 | 89 | 163 |
| 2020 June | 54 | 74 | 128 |
| 2020 May | 70 | 101 | 171 |
| 2020 April | 66 | 108 | 174 |
| 2020 March | 67 | 125 | 192 |
| 2020 February | 79 | 103 | 182 |
| 2020 January | 75 | 72 | 147 |
| 2019 December | 71 | 72 | 143 |
| 2019 November | 78 | 74 | 152 |
| 2019 October | 73 | 736 | 809 |
| 2019 September | 64 | 72 | 136 |
| 2019 August | 44 | 29 | 73 |
| 2019 July | 92 | 51 | 143 |
| 2019 June | 97 | 71 | 168 |
| 2019 May | 98 | 94 | 192 |
| 2019 April | 100 | 85 | 185 |
| 2019 March | 76 | 116 | 192 |
| 2019 February | 82 | 112 | 194 |
| 2019 January | 44 | 43 | 87 |
| 2018 December | 60 | 55 | 115 |
| 2018 November | 54 | 76 | 130 |
| 2018 October | 75 | 48 | 123 |
| 2018 September | 114 | 63 | 177 |
| 2018 May | 28 | 2 | 30 |
| 2018 April | 49 | 8 | 57 |
| 2018 March | 27 | 10 | 37 |
| 2018 February | 5 | 6 | 11 |
| 2018 January | 9 | 12 | 21 |
| 2017 December | 11 | 23 | 34 |
| 2017 November | 56 | 63 | 119 |
| 2017 October | 55 | 31 | 86 |
| 2017 September | 7 | 40 | 47 |
| 2017 August | 16 | 75 | 91 |
| 2017 July | 4 | 54 | 58 |
| 2017 June | 47 | 52 | 99 |
| 2017 May | 29 | 43 | 72 |
| 2017 April | 11 | 93 | 104 |
| 2017 March | 16 | 99 | 115 |
| 2017 February | 13 | 84 | 97 |
| 2017 January | 3 | 27 | 30 |
| 2016 December | 8 | 24 | 32 |
| 2016 November | 20 | 66 | 86 |
| 2016 October | 18 | 51 | 69 |
| 2016 September | 54 | 81 | 135 |
| 2016 August | 89 | 36 | 125 |
| 2016 July | 62 | 38 | 100 |
| 2016 June | 59 | 41 | 100 |
| 2016 May | 72 | 41 | 113 |
| 2016 April | 24 | 0 | 24 |
| 2016 March | 39 | 0 | 39 |
| 2016 February | 20 | 2 | 22 |
| 2016 January | 21 | 20 | 41 |
| 2015 December | 29 | 21 | 50 |
| 2015 November | 29 | 10 | 39 |
| 2015 October | 5 | 1 | 6 |
| 2015 September | 2 | 0 | 2 |
Show all
