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Vol. 32. Issue 4.
Pages 205-208 (April 1996)
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Vol. 32. Issue 4.
Pages 205-208 (April 1996)
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Candidiasis laríngea aislada. Descripción de 2 casos y revisión de la literatura
Isolated laryngeal candidiasis. Two cases and review of the literature
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D. Alba1, F. Molina, J.J. Vázquez
Departamentos de Medicina Interna. Hospital La Paz. Madrid
C. Perna*, L. Ortega*
* Departamentos de Anatomía Patológica. Hospital La Paz. Madrid
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La infección laríngea por Candida es infrecuente y habitualmente secundaria a candidiasis pulmonar o diseminada.

La candidiasis laríngea aislada (CLA) es una entidad rara, aunque su incidencia puede estar infraestimada. Describimos 2 pacientes con CLA documentados en la necropsia: un varón de 45 años con fibrosis pulmonar y una niña de 4 años con leucemia aguda mieloblástica. Los síntomas más frecuentes de CLA son ronquera y disfagia. El método diagnóstico más eficaz es la laringoscopia con toma de muestras para cultivo y/o estudio histopatológico. La laringoscopia muestra habitualmente placas blanquecinas laríngeas. La mayoría de pacientes con CLA tienen alguna enfermedad asociada y/o otros factores predisponentes, con frecuencia terapia previa con antibióticos. El tratamiento más eficaz es la anfotericina B intravenosa, si bien son útiles otros antimicóticos. El reconocimiento y la terapia tempranos de la entidad limitan su morbilidad y, potencialmente, previenen la diseminación sistémica.

Palabras clave:
Candidiasis laríngea
Candidiasis aislada
Laringitis
Epiglotitis

Infection of the larynx by Candida is rare and usually accompanies lung or disseminated candidiasis. The incidence of isolated laryngeal candidiasis (ILC) is low, although it may be underestimated. We describe 2 patients with ILC confirmed during autopsy: a 45-years-old male with pulmonary fibrosis and a 4-years-old girl with acute myeloblastic leukemia. Hoarseness and dysphagia are the most common symptoms of ILC. The most effective diagnostic technique is laryngoscopy with specimen culture and/or histopathology. Specimens usually show whitish plaques on the larynx. Most ILC patients have some associated disease and/or predisposing factors, with frequent antibiotic treatment prior to the advent of candidiasis. Intravenous amphotericin B provides the most effective therapy, although other antimycotics are also useful. Early diagnosis and initiation of therapy curtail the disease and can prevent systemic dissemination.

Key words:
Laryngeal candidiasis
Isolated candidiasis
Laryngitis
Epiglottitis
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Copyright © 1996. Sociedad Española de Neumología y Cirugía Torácica
Archivos de Bronconeumología
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