Candidiasis laríngea aislada. Descripción de 2 casos y revisión de la literatura
Isolated laryngeal candidiasis. Two cases and review of the literature
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Descripción de 2 casos y revisión de la literatura" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "205" "paginaFinal" => "208" ] ] "autores" => array:2 [ 0 => array:4 [ "autoresLista" => "D. Alba, F. Molina, J.J. Vázquez" "autores" => array:3 [ 0 => array:3 [ "nombre" => "D." "apellidos" => "Alba" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "F." "apellidos" => "Molina" ] 2 => array:2 [ "nombre" => "J.J." "apellidos" => "Vázquez" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Departamentos de Medicina Interna. Hospital La Paz. Madrid" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "1" "correspondencia" => "Correspondencia: Isabel Rosillo, 8, l.° C. 28100 Madrid." ] ] ] 1 => array:3 [ "autoresLista" => "C. Perna, L. Ortega" "autores" => array:2 [ 0 => array:3 [ "nombre" => "C." "apellidos" => "Perna" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0010" ] ] ] 1 => array:3 [ "nombre" => "L." "apellidos" => "Ortega" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0010" ] ] ] ] "afiliaciones" => array:1 [ 0 => array:3 [ "entidad" => "Departamentos de Anatomía Patológica. Hospital La Paz. Madrid" "etiqueta" => "*" "identificador" => "aff0010" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Isolated laryngeal candidiasis. Two cases and review of the literature" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "1995-08-28" "fechaAceptado" => "1995-10-11" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec546142" "palabras" => array:4 [ 0 => "Candidiasis laríngea" 1 => "Candidiasis aislada" 2 => "Laringitis" 3 => "Epiglotitis" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec546143" "palabras" => array:4 [ 0 => "Laryngeal candidiasis" 1 => "Isolated candidiasis" 2 => "Laryngitis" 3 => "Epiglottitis" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">La infección laríngea por Candida es infrecuente y habitualmente secundaria a candidiasis pulmonar o diseminada.</p><p id="spar1005" class="elsevierStyleSimplePara elsevierViewall">La candidiasis laríngea aislada (CLA) es una entidad rara, aunque su incidencia puede estar infraestimada. Describimos 2 pacientes con CLA documentados en la necropsia: un varón de 45 años con fibrosis pulmonar y una niña de 4 años con leucemia aguda mieloblástica. Los síntomas más frecuentes de CLA son ronquera y disfagia. El método diagnóstico más eficaz es la laringoscopia con toma de muestras para cultivo y/o estudio histopatológico. La laringoscopia muestra habitualmente placas blanquecinas laríngeas. La mayoría de pacientes con CLA tienen alguna enfermedad asociada y/o otros factores predisponentes, con frecuencia terapia previa con antibióticos. El tratamiento más eficaz es la anfotericina B intravenosa, si bien son útiles otros antimicóticos. El reconocimiento y la terapia tempranos de la entidad limitan su morbilidad y, potencialmente, previenen la diseminación sistémica.</p></span>" ] "en" => array:1 [ "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Infection of the larynx by Candida is rare and usually accompanies lung or disseminated candidiasis. The incidence of isolated laryngeal candidiasis (ILC) is low, although it may be underestimated. We describe 2 patients with ILC confirmed during autopsy: a 45-years-old male with pulmonary fibrosis and a 4-years-old girl with acute myeloblastic leukemia. Hoarseness and dysphagia are the most common symptoms of ILC. The most effective diagnostic technique is laryngoscopy with specimen culture and/or histopathology. Specimens usually show whitish plaques on the larynx. Most ILC patients have some associated disease and/or predisposing factors, with frequent antibiotic treatment prior to the advent of candidiasis. Intravenous amphotericin B provides the most effective therapy, although other antimycotics are also useful. Early diagnosis and initiation of therapy curtail the disease and can prevent systemic dissemination.</p></span>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:22 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Severe candidal infections: clinical perspective, immune defense mechanisms, and current concepts of therapy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "J.E. Edwards Jr." 1 => "R.I. Lehrer" 2 => "E.R. Stiehm" 3 => "T.J. Fisher" 4 => "L.S. 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| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 28 | 2 | 30 |
| 2024 October | 201 | 41 | 242 |
| 2024 September | 199 | 54 | 253 |
| 2024 August | 197 | 63 | 260 |
| 2024 July | 120 | 42 | 162 |
| 2024 June | 226 | 31 | 257 |
| 2024 May | 139 | 32 | 171 |
| 2024 April | 158 | 30 | 188 |
| 2024 March | 197 | 32 | 229 |
| 2024 February | 47 | 37 | 84 |
| 2024 January | 0 | 3 | 3 |
| 2023 December | 0 | 3 | 3 |
| 2023 November | 0 | 4 | 4 |
| 2023 October | 3 | 10 | 13 |
| 2023 September | 4 | 10 | 14 |
| 2023 August | 7 | 16 | 23 |
| 2023 July | 2 | 21 | 23 |
| 2023 June | 0 | 4 | 4 |
| 2023 May | 0 | 2 | 2 |
| 2023 March | 21 | 4 | 25 |
| 2023 February | 108 | 34 | 142 |
| 2023 January | 74 | 56 | 130 |
| 2022 December | 78 | 50 | 128 |
| 2022 November | 125 | 26 | 151 |
| 2022 October | 88 | 41 | 129 |
| 2022 September | 84 | 36 | 120 |
| 2022 August | 77 | 38 | 115 |
| 2022 July | 86 | 43 | 129 |
| 2022 June | 66 | 45 | 111 |
| 2022 May | 55 | 37 | 92 |
| 2022 April | 52 | 46 | 98 |
| 2022 March | 73 | 69 | 142 |
| 2022 February | 89 | 57 | 146 |
| 2022 January | 76 | 69 | 145 |
| 2021 December | 53 | 44 | 97 |
| 2021 November | 50 | 36 | 86 |
| 2021 October | 54 | 56 | 110 |
| 2021 September | 51 | 44 | 95 |
| 2021 August | 50 | 46 | 96 |
| 2021 July | 58 | 35 | 93 |
| 2021 June | 50 | 41 | 91 |
| 2021 May | 46 | 50 | 96 |
| 2021 April | 115 | 67 | 182 |
| 2021 March | 84 | 38 | 122 |
| 2021 February | 64 | 20 | 84 |
| 2021 January | 49 | 24 | 73 |
| 2020 December | 46 | 17 | 63 |
| 2020 November | 54 | 15 | 69 |
| 2020 October | 53 | 23 | 76 |
| 2020 September | 64 | 15 | 79 |
| 2020 August | 73 | 32 | 105 |
| 2020 July | 54 | 18 | 72 |
| 2020 June | 49 | 9 | 58 |
| 2020 May | 71 | 27 | 98 |
| 2020 April | 56 | 16 | 72 |
| 2020 March | 44 | 36 | 80 |
| 2020 February | 56 | 23 | 79 |
| 2020 January | 60 | 31 | 91 |
| 2019 December | 45 | 48 | 93 |
| 2019 November | 32 | 48 | 80 |
| 2019 October | 22 | 46 | 68 |
| 2019 September | 19 | 81 | 100 |
| 2019 August | 15 | 40 | 55 |
| 2019 July | 10 | 67 | 77 |
| 2019 June | 16 | 67 | 83 |
| 2019 May | 19 | 64 | 83 |
| 2019 April | 37 | 76 | 113 |
| 2019 March | 14 | 42 | 56 |
| 2019 February | 5 | 18 | 23 |
| 2019 January | 5 | 20 | 25 |
| 2018 December | 18 | 28 | 46 |
| 2018 November | 22 | 46 | 68 |
| 2018 October | 28 | 55 | 83 |
| 2018 September | 14 | 56 | 70 |
| 2018 May | 6 | 2 | 8 |
| 2018 April | 14 | 8 | 22 |
| 2018 March | 6 | 7 | 13 |
| 2018 February | 8 | 13 | 21 |
| 2018 January | 5 | 5 | 10 |
| 2017 December | 9 | 27 | 36 |
| 2017 November | 18 | 54 | 72 |
| 2017 October | 8 | 50 | 58 |
| 2017 September | 4 | 50 | 54 |
| 2017 August | 13 | 73 | 86 |
| 2017 July | 4 | 58 | 62 |
| 2017 June | 9 | 55 | 64 |
| 2017 May | 25 | 72 | 97 |
| 2017 April | 8 | 51 | 59 |
| 2017 March | 6 | 81 | 87 |
| 2017 February | 4 | 67 | 71 |
| 2017 January | 9 | 22 | 31 |
| 2016 December | 13 | 37 | 50 |
| 2016 November | 22 | 51 | 73 |
| 2016 October | 19 | 60 | 79 |
| 2016 September | 22 | 39 | 61 |
| 2016 August | 33 | 31 | 64 |
| 2016 July | 23 | 19 | 42 |
| 2016 June | 30 | 23 | 53 |
| 2016 May | 13 | 8 | 21 |
| 2016 April | 9 | 0 | 9 |
| 2016 March | 7 | 0 | 7 |
| 2016 February | 8 | 0 | 8 |
| 2016 January | 20 | 8 | 28 |
| 2015 December | 28 | 21 | 49 |
| 2015 November | 25 | 11 | 36 |
| 2015 October | 6 | 2 | 8 |
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