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Vol. 21. Issue 6.
Pages 257-261 (November - December 1985)
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Vol. 21. Issue 6.
Pages 257-261 (November - December 1985)
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Alfa-1-antitripsina en niños con infecciones cronicas del aparato respiratorio
Alpha-1-antitrypsin (AAT) in children with chronic respiratory tract infections
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A.C.J. Ezeoke, Anjali sherma
Department of Clinical Pathology. College of Medical Sciences. University of Calabar. Calabar, Cross River State. Nigeria
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En 22 niños, 13 niñas y 9 niños de edades comprendidas entre los 6 meses y los 12 años, con infecciones respiratorias crónicas, se observaron niveles séricos de alfa-l-antitripsina entre 17,1 y 290mg/dl, en comparación con los de un grupo control, entre 205 y 290 mg/dl. Se observó una diferencia estadísticamente significativa (p<0,01) entre los niños con infecciones crónicas del aparato respiratorio y los del grupo control. Dado que los pacientes con niveles bajos de alfa-l-antitripsina mostraban un esquema de enfermedad que los distinguía del grupo control, se concluyó que los niveles séricos de alfa-l-antitripsina constituyen un factor importante en la patogénesis de las enfermedades pulmonares crónicas.

Twenty-two children from chronic respiratory tract infections, 13 females and 9 males between 6 months to 12 years were found to have serum alpha-l-antitrypsin levels ranging from 17.1-290 mg/dl as compared with control 205-440mg/dl. There was a significant difference (p<0.01) between the children with chronic respiratory tract infections and control. Since the patients with decreased alpha-l-antitrypsin had a pattern of disease which distinguished them from control group, it could be concluded that serum levels of alpha-l-antitrypsin is an important factor in the pathogenesis of chronic pulmonary

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Copyright © 1985. Sociedad Española de Neumología y Cirugía Torácica
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