Alfa-1-antitripsina en niños con infecciones cronicas del aparato respiratorio
Alpha-1-antitrypsin (AAT) in children with chronic respiratory tract infections
A.C.J. Ezeoke, Anjali sherma
Department of Clinical Pathology. College of Medical Sciences. University of Calabar. Calabar, Cross River State. Nigeria
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Diaz jimenez" "autores" => array:1 [ 0 => array:2 [ "nombre" => "J.P." "apellidos" => "Diaz jimenez" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615320925?idApp=UINPBA00003Z" "url" => "/03002896/0000002100000006/v1_201509151106/S0300289615320925/v1_201509151106/es/main.assets" ] "es" => array:13 [ "idiomaDefecto" => true "titulo" => "Alfa-1-antitripsina en niños con infecciones cronicas del aparato respiratorio" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "257" "paginaFinal" => "261" ] ] "autores" => array:1 [ 0 => array:3 [ "autoresLista" => "A.C.J. Ezeoke, Anjali sherma" "autores" => array:2 [ 0 => array:3 [ "preGrado" => "MD (CD Juárez), Ph. D. (Lond.)" "nombre" => "A.C.J." "apellidos" => "Ezeoke" ] 1 => array:2 [ "preGrado" => "M.B., B.S., M.D. (Rohtak)" "apellidos" => "Anjali sherma" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Department of Clinical Pathology. College of Medical Sciences. University of Calabar. Calabar, Cross River State. Nigeria" "identificador" => "aff0005" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Alpha-1-antitrypsin (AAT) in children with chronic respiratory tract infections" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "1985-09-04" "fechaAceptado" => "1986-06-15" "tieneResumen" => true "resumen" => array:2 [ "es" => array:1 [ "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">En 22 niños, 13 niñas y 9 niños de edades comprendidas entre los 6 meses y los 12 años, con infecciones respiratorias crónicas, se observaron niveles séricos de alfa-l-antitripsina entre 17,1 y 290<span class="elsevierStyleHsp" style=""></span>mg/dl, en comparación con los de un grupo control, entre 205 y 290 mg/dl. Se observó una diferencia estadísticamente significativa (p<span class="elsevierStyleHsp" style=""></span><<span class="elsevierStyleHsp" style=""></span>0,01) entre los niños con infecciones crónicas del aparato respiratorio y los del grupo control. Dado que los pacientes con niveles bajos de alfa-l-antitripsina mostraban un esquema de enfermedad que los distinguía del grupo control, se concluyó que los niveles séricos de alfa-l-antitripsina constituyen un factor importante en la patogénesis de las enfermedades pulmonares crónicas.</p></span>" ] "en" => array:1 [ "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Twenty-two children from chronic respiratory tract infections, 13 females and 9 males between 6 months to 12 years were found to have serum alpha-l-antitrypsin levels ranging from 17.1-290 mg/dl as compared with control 205-440<span class="elsevierStyleHsp" style=""></span>mg/dl. There was a significant difference (p<span class="elsevierStyleHsp" style=""></span><<span class="elsevierStyleHsp" style=""></span>0.01) between the children with chronic respiratory tract infections and control. Since the patients with decreased alpha-l-antitrypsin had a pattern of disease which distinguished them from control group, it could be concluded that serum levels of alpha-l-antitrypsin is an important factor in the pathogenesis of chronic pulmonary</p></span>" ] ] "bibliografia" => array:2 [ "titulo" => "Bibliografía" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:16 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Electrophoretic —globulin pattern of serum —antitrypsin deficiency" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "G.B. Laurell" 1 => "S. 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