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Vol. 33. Issue 1.
Pages 41-49 (January 1997)
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Vol. 33. Issue 1.
Pages 41-49 (January 1997)
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Antibioterapia inhalada
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M. Vendrell Relat*, J. de Gracia Roldán
Servicio de Neumología. Hospital General Universitario Vall d’Hebron. Barcelona
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Bibliografía
[1.]
J.C. Yernault.
Inhalation therapy: a historical perspective.
Eur Respir Rev, 4 (1994), pp. 65-67
[2.]
S. Clarke.
Principies of inhaled therapy.
Respiratory medicine, pp. 485-492
[3.]
P. Vermeire.
European trends in inhalation therapy.
Eur Respir Rev, 4 (1994), pp. 89-91
[4.]
J. Sanchís.
New trends in aerosol therapy: the clinicians view.
Eur Respir Rev, 4 (1994), pp. 106-107
[5.]
P. Cole, D.E. Robert.
High dose antibiotic is logical, effective, and economical in treatment of severe bronchial sepsis.
Lancet, 29 (1983), pp. 248-249
[6.]
P.J. Cole, D.E. Roberts, S.F. Davies, R.K. Knight.
A simple oral antimicrobial regimen effective in severe chronic bronchial suppuration associated with culturable Haemophilus influenzae.
J Antimicrob Chemother, 11 (1983), pp. 109-113
[7.]
D.C. Currie, N.D. Garbett, K.L. Chan, E. Higgd, H. Todd, M.V. Chadwick, et al.
Double-blind randomized study of prolonged higherdose oral amoxycillin in purulent bronchiectasis.
Q J Med, 280 (1990), pp. 799-816
[8.]
A. Pines, H. Raafat, K. Plucinski.
Gentamicin and colistin in chronic purulent bronchial infections.
Brit Med J, 2 (1967), pp. 543-545
[9.]
M.E. Hodson, A.R.L. Penketh, J.C. Batten.
Aerosol carbenicillin and gentamicin treatment of Pseudomonas (aeruginosa infection in patients with cystic fibrosis.
Lancet, 2 (1981), pp. 1.137-1.139
[10.]
G.S. Leoung, D.W. Feigal, B. Montgomery, K. Corkery, L. Wardlaw, M. Adams, et al.
Aerosolized pentamidine for prophylaxis against Pneumocystis carinii pneumonia.
N Engl J Med, 323 (1990), pp. 769-775
[11.]
B. Hirschel, A. Lazzarin, P. Chopard, M. Opravil, H.J. Furrer, S. Rüttimann, et al.
A controlled study of inhaled pentamidine for primary prevention of Pneumocvstis carinii pneumonia.
N Engl J Med, 324 (1991), pp. 1.079-1.083
[12.]
A. Román, J. Gavalda, C. Bravo, M. Montané, V. Monforte, C. Murio, et al.
Prophylaxis with amphotericin B nebulized and ganciclovir (DHPG) in lung transplant patients.
Eur Respir J, 7 (1994), pp. 249
[13.]
E. Conneally, M.T. Cafferkey, P.A. Daly, C.T. Keane, S.R. McCann.
Nebulized amphotericin B as prophylaxis against invasive aspergillosis in granulocytopenic patients.
Bone Marrow Transplantation, 5 (1990), pp. 403-406
[14.]
M. Vendrell, J. De Gracia, C. Mayordomo, M. Miravitlles, F. Morell.
Efficacy of aerosolized antibiotics in bronchiectasis.
Am J Respir Crit Care Med, 151 (1995), pp. 475
[15.]
A. Rosell, R. Orriols, J. Roig, E. Balcells, P. Bellver, A. Ferrer, et al.
Out-patient inhaled antibiotic treatment in non-mucoviscidotic patients with bronchiectasis colonized by Pseudomonas aeruginosa.
Eur Respir J, 8 (1995), pp. 128
[16.]
R.A. Stockley, S.L. Hill, D. Burnett.
Nebulized amoxicillin in chronic purulent bronchiectasis.
Clinical Therapeutics, 7 (1985), pp. 593-599
[17.]
A.L. Smith, B. Ramsey.
Aerosol administration of antibiotics.
Respiration, 62 (1995), pp. 19-24
[18.]
I. MacLuscky, H. Levison, R. Gold, F.J. McLaughlin.
Inhaled antibiotics in cystic fibrosis: is there a therapeutic effect?.
J Pediatr, 108 (1986), pp. 861-865
[19.]
J.M. Littlewood, S.W. Smye, H. Cunliffe.
Aerosol antibiotic treatment in cystic fibrosis.
Arch Dis Child, 68 (1993), pp. 788-792
[20.]
R.J. Stead, M.E. Hodson, J.C. Batten.
Inhaled ceftazidime compared with gentamicin and carbenicillin in older patients with cystic fibrosis infected with Pseudomonas aeruginosa.
Br J Dis Chest, 81 (1987), pp. 272
[21.]
G. Steinkamp, B. Tümler, M. Gappa, A. Albus, J. Potel, G. Doring, et al.
Long-term tobramycin aerosol therapy in cystic fibrosis.
Pediatr Pulmonol, 6 (1989), pp. 91-98
[22.]
A.L. Smith, B.W. Ramsey, D.L. Hedges, B. Hack, J. Williams-Warren, A. Weber, et al.
Safety of aerosol tobramycin administration for 3 months to patients with cystic fibrosis.
Pediatr Pulmonol, 7 (1989), pp. 265-271
[23.]
T. Jensen, S.S. Pedersen, S. Garne, C. Heilmann, N. Hoiby, C. Koch.
Colistin inhalation therapy in cystic fibrosis patients with chronic Pseudomonas aeruginosa lung infection.
J Antimicrob Chemother, 19 (1987), pp. 831-838
[24.]
I.B. MacLusky, R. Gold, M. Corey, H. Levison.
Long-term effects of inhaled tobramycin in patients with cystic fibrosis colonized with Pseudomonas aeruginosa.
Pediatr Pulmonol, 7 (1989), pp. 42-48
[25.]
B.W. Ramsey, H.L. Dorkin, J.D. Eisenberg, R.L. Gibson, I.R. Harwood, R.M. Kravitz, et al.
Efficacy of aerosolized tobramycin in patients with cystic fibrosis.
N Engl J Med, 328 (1993), pp. 1.740-1.746
[26.]
S.L. Hill, R.A. Stockley.
Effect of short and long term antibiotic response on lung function in bronchiectasis.
Thorax, 41 (1986), pp. 798-800
[27.]
G. Nolan, P. Mclvor, H. Levison, P.C. Fleming, M. Corey, R. Gold.
Antibiotic prophylaxis in cystic fibrosis: inhaled cephaloridine as an adjunct to oral cloxacillin.
J Pediatr, 101 (1982), pp. 626-630
[28.]
D.M. Cooper, M. Harris, I. Mitchell.
Comparison of intravenous and inhalation antibiotic therapy in acute pulmonary deterioration in cystic fibrosis.
Am Rev Respir Dis, 131 (1985), pp. 242
[29.]
Hoiby N, Pedersen SS, Shand GH, Döring G, Holder IA, editores. Pseudomonas aeruginosa infection. Antibiot Chemother 1989; 42: 229-236.
[30.]
U.B. Schaad, J. Wedgwood-Krucko, S. Suter, R. Kraemer.
Efficacy of inhaled amikacin as adjunct to intravenous combination therapy (ceftazidime and amikacin) in cystic fibrosis.
J Pediatr, 111 (1987), pp. 599-605
[31.]
D. Stephens, N. Garey, A. Isles, H. Levinson, R. Gold.
Efficacy of inhaled tobramycin in the treatment of pulmonary exacerbations in children with cystic fibrosis.
Pediatr Infect Dis, 3 (1983), pp. 209-211
[32.]
J.M. Littlewood, M.G. Miller, A.T. Ghoneim, C.H. Ramsden.
Nebulised colomycin for early pseudomonas colonisation in cystic fibrosis.
[33.]
N.H. Valerius, C. Koch, N. Hoiby.
Prevention of chronic Pseudomonas (aeruginosa colonisation in cystic fibrosis by early treatment.
Lancet, 338 (1991), pp. 725-726
[34.]
F. Baranda, C. Vázquez, J. Elorz, R. Lejarreta, E. Ciruelos, P. Gil.
Tratamiento precoz de la colonización bronquial por Pseudomonas aeruginosa en la fibrosis quística.
Arch Bronconeumol, 30 (1994), pp. 76
[35.]
D.J. Touw, R.W. Brimicombe, M.E. Hodson, H.G.M. Heijerman, W. Bakker.
Inhalation of antibiotics in cystic fibrosis.
Eur Respir J, 8 (1995), pp. 1.594-1.604
[36.]
M.A. Wall, A.B. Terry, J. Eisenberg, M. McNamara, R. Cohen.
Inhaled antibiotics in cystic fibrosis.
Lancet, 1 (1983), pp. 1.325
[37.]
N. Hoiby.
Antibiotic therapy for chronic infection of Pseudomonas in the lung.
[38.]
R.A. Stockley, S.L. Hill, H.M. Morrison, C.M. Starkie.
Elastolytic activity of sputum and its relation to purulence and to lung function in patients with bronchiectasis.
Thorax, 39 (1984), pp. 408-413
[39.]
P. Lloberes, E. Montserrat, J.M. Montserrat, C. Picado.
Sputum sol phase proteins and elastase activity in patients with clinically stable bronchiectasis.
Thorax, 47 (1992), pp. 88-92
[40.]
R. Sepper, Y.T. Konttinen, T. Ingman, T. Sorsa.
Presence, activities, and molecular forms of cathepsin G, elastase, al-antitrypsin, and alantichymotrypsin in bronchiectasis.
J Clin Immunol, 15 (1995), pp. 27-34
[41.]
D.C. Currie, E. Higgs, S. Metcalfe, D.E. Roberts, P.J. Cole.
Simple method of monitoring colonising microbial load in chronic bronchial sepsis: pilot comparison of reduction in colonising microbial load with antibiotics given intermittently and continuously.
J Clin Pathol, 40 (1987), pp. 830-836
[42.]
S.L. Hill, D. Burnett, K.A. Hewetson, R.A. Stockley.
The response of patients with purulent bronchiectasis to antibiotics for four months.
Q J Med, 250 (1988), pp. 163-173
[43.]
C. Rayner, G. Tillotson, P.J. Cole, R. Wilson.
Efficacy and safety of long-term ciprofloxacin in the management of severe bronchiectasis.
J Antimicrob Chemother, 34 (1994), pp. 149-156
[44.]
R.A. Stockley, S.L. Hill, H.M. Morrison.
Effect of antibiotic treatment on sputum elastase in bronchiectatic outpatients in a stable clinical State.
Thorax, 39 (1984), pp. 414-419
[45.]
S.L. Hill, H.M. Morrison, D. Bumett, R.A. Stockley.
Short term response of patients with bronchiectasis to treatment with amoxycillin given in standard or high doses orally or by inhalation.
Thorax, 41 (1986), pp. 559-565
[46.]
J. Symonds.
Penetration of antibiotics into the respiratory tract.
Br Med J, 294 (1987), pp. 1.181-1.182
[47.]
R.A. Stockley, S.L. Hill.
Appropriate dose antibiotics in chronic bronchial sepsis.
Lancet, 27 (1984), pp. 977-978
[48.]
S.L. Gerson, G.H. Talbot, S. Hurwitz, B.L. Strom, B.J. Lusk, P.A. Cassileth.
Prolonged granulocytopenia: the major risk factor for invasive pulmonary aspergillosis in patients with acute leukemia.
Ann Intern Med, 100 (1984), pp. 345-351
[49.]
M.M.E. Schneider, A.I.M. Hoepelman, J.K.M. Eeftinck Schattenkerk, T.L. Nielsen, Y. Van der Graaf, J.P.H.J. Frissen, et al.
A controlled trial of aerosolized pentamidine or trimethoprim-sulfamethoxazole as primary prophylaxis against Pneumocystis carinii pneumonía in patients with human immunodeficiency virus infection.
N Engl J Med, 327 (1992), pp. 1.836-1.841
[50.]
W.D. Hardy, J. Feinberg, D.M. Finkelstein, M.E. Power, W. He, C. Kaczka, et al.
A controlled trial of trimethoprim-sulfamethoxazole or aerosolized pentamidine for secondary prophylaxis of Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome: AIDS Clinical Trials Group protocol 021.
N Engl J Med, 327 (1992), pp. 1.842-1.848
[51.]
S.A. Bozzette, D.M. Finkelstein, S.A. Spector, P. Frame, W.G. Powderly, W. He, et al.
A randomized trial of three antipneumocystis agents in patients with advanced human immunodeficiency virus infection.
N Engl J Med, 332 (1995), pp. 693-699
[52.]
G.W. Soo Hoo, Z. Mohsenifar, R.D. Meyer.
Inhaled or intravenous pentamidine therapy for Pneumocystis carinii pneumonia in AIDS. A randomized trial.
Ann Intern Med, 113 (1990), pp. 195-202
[53.]
J.E. Conte, D. Chernoff, D.W. Feigal, P. Joseph, C. McDonald, J.A. Golden.
Intravenous or inhaled pentamidine for treating Pneumocvstis carinii pneumonia in AIDS. A randomized trial.
Ann Intern Med, 113 (1990), pp. 203-209
[54.]
R.F. Miller, P.G. Godfrey-Faussett, S.J.G. Semple.
Nebulised pentamidine as treatment for Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome.
Thorax, 44 (1989), pp. 565-569
[55.]
S.P. Conway, A. Watson, M. Pond, S. Bayston, R. Booth.
Ghonheim. Sputum gentamicin (G) levels after delivery by rotahaler and nebuliser.
Eur Respir J, 6 (1993), pp. 230
[56.]
J.M. Goldman, S.M. Boyston, S. O’Connor, R.E. Meigh.
Inhaled micronised gentamicin powder: a new delivery system.
Thorax, 45 (1990), pp. 939-940
[57.]
M. Götz, A. Schimmelpfeennig, D.Y. Koller.
Aerosolized colistin in patients with cystic fibrosis (CF): effects on pulmonary function and markers of inflamation.
Ped Pulmonol, (1993), pp. 265
[58.]
H.L. Chua, G.C. Collins, P.N. Le Souëf.
Bronchial response to nebulized antibiotics in children with cystic fibrosis.
Eur Respir J, 3 (1990), pp. 1.114-1.116
[59.]
S.A. Stout, H. Derendorf.
Local treatment of respirator infections with antibiotics.
Drug Intell Clin Pharm, 21 (1987), pp. 322-329
[60.]
S.P. Newman, G. Woodman, S.W. Clarke.
Deposition of carbenicillin aerosols in cystic fibrosis: effects of nebuliser system and breathing pattem.
Thorax, 43 (1988), pp. 318-322
[61.]
P.K. Hurley, S.W. Smye, H. Cunliffe.
Assesment of antibiotic aerosol generation using commercial jet nebulizers.
J Aerosol Med, 7 (1994), pp. 217-228
[62.]
J.S. Ilowite, J.D. Gorvoy, G.C. Smaldone.
Quantitative deposition of aerosolized gentamicin in cystic fibrosis.
Am Rev Respir Dis, 136 (1987), pp. 1.445-1.449
[63.]
A.H. Kendrick, E.C. Smith, J. Denyer.
Nebulizers-fill volume, residual volume and matching of nebulizer to compressor.
Respiratory Medicine, 89 (1995), pp. 157-159
[64.]
S.P. Newman, P.G.D. Pellow, S.W. Clarke.
Choice of nebulisers and compressors for delivery of carbenicillin aerosol.
Eur J Respir Dis, 69 (1986), pp. 160-168
[65.]
S.P. Newman, P.G.D. Pellow, S.W. Clarke.
Efficient nebulisation of powdered antibiotics.
Int J Pharm, 36 (1987), pp. 55-60
[66.]
S.P. Newman, P.G.D. Pellow, M.M. Clay, S.W. Clarke.
Evaluation of jet nebulizers for use with gentamicin solution.
Thorax, 40 (1985), pp. 671-676
[67.]
S.P. Newman, P.G.D. Pellow, S.W. Clarke.
Droplet size distributions of nebulised aerosols for inhalation therapy.
Clin Physiol Meas, 7 (1986), pp. 139-146
[68.]
D.T. Loffert, D. Ikle, H.S. Nelson.
A comparison of commercial jet nebulizers.
Chest, 106 (1994), pp. 1.788-1.793
[69.]
F. Faurisson, J.F. Dessanges, A. Grimfeld, R. Beaulieu, M.D. Kitzis, G. Peytavin, et al.
Nebuliser performance: AFLM study.
Respiration, 62 (1995), pp. 13-18
[70.]
J.G. Hardy, S.P. Newman, M. Knoch.
Lung deposition from four nebulizers.
Respiratory Medicine, 87 (1993), pp. 461-465
[71.]
S. Clarke.
Principies of inhaled therapy.
Respiratory medicine, pp. 1.286-1.316
[72.]
J.R. Balmes, R. Chaisson, M.B. Dolovich, R. Fallat, R.M. Kacmarck, H. Matthys, et al.
Aerosol Consensus Statement.
Chest, 100 (1991), pp. 1.106-1.119
[73.]
S. Mukhopadhyay, G.E. Staddon, C. Eastman, M. Palmer, E. Rhys, F. Carswell.
The quantitative distribution of nebulized antibiotic in the lung in cystic fibrosis.
Respiratory Med, 88 (1994), pp. 203-211
[74.]
C.C. Kuni, W.E. Regelmann, R.P. DuCret, R.J. Boudreau, J.R. Budd.
Aerosol scintigraphy in the assesment of therapy for cystic fibrosis.
Clin Nucl Med, 17 (1992), pp. 90-93
[75.]
S. Oie, A. Kamiya.
Bacterial contamination of aerosol Solutions containing antibiotics.
Microbios, 82 (1995), pp. 109-113
[76.]
K.C. Pitchford, M. Corey, A.K. Highsmith, R. Perlman, R. Bannatyne, R. Gold, et al.
Pseudomonas species contamination of cystic fibrosis patients’ home inhalation equipment.
J Pediatr, 111 (1987), pp. 212-216
[77.]
R.J. Kuhn, A.H. Lubin, P.R. Jones, M.C. Nahata.
Bacterial contamination of aerosol Solutions used to treat cystic fibrosis.
Am J Hosp Pharm, 39 (1982), pp. 308-309
[78.]
G. Hüls, H. Lindemann, S. Lüdtke, R. Füssle, H.G. Schiefer.
Cleaning of jet nebulizers used by outpatients.
Eur Respir J, 6 (1993), pp. 230
[79.]
Recomendaciones SEPAR.
Normativa sobre control microbiológico en los equipos de función y terapia respiratoria.
Doyma, (1995),
[80.]
Y. Valcke, R. Pauwels, M. Van Der Straeten.
Pharmacokinetics of antibiotics in the lungs.
Eur Respir J, 3 (1990), pp. 715-722
[81.]
Drug Evaluations Annual.
American Medical Association.
11.ª, Saunders, (1995),
[82.]
A. Ferrer, P. Bellver, N. Cobos, S. Liñán, G. Codina, F. Fernández.
Fibrosis quística: Estudio microbiológico durante un período de 8 años.
Arch Bronconeumol, 31 (1995), pp. 494-500
[83.]
M. Maddison, M. Dodd, A.K. Webb.
Nebulized colistin causes chest tightness in adults with cystic fibrosis.
Respir Med, 88 (1994), pp. 145-147
[84.]
E.J. Perea, M.C. García-Iglesias, R. Martín, R. Verdaguer, J. García, R. Borrás, et al.
Resistencias en Haemophilus influenzae en España.
Enf Infec y Microbiol Clin, 4 (1988), pp. 16-24
[85.]
J. Dubois, T. Bartter, J. Gryn, M.R. Pratter.
The physiologic effects of inhaled amphotericin B.
Chest, 108 (1995), pp. 750-753
[86.]
M. Katzman, W. Meade, K. Iglar, A. Rachlis, P. Berger, C.K. Chan.
High incidence of bronchospasm with regular administration of aerosolized pentamidine.
Chest, 101 (1992), pp. 79-81
[87.]
K.M. Jules-Elysee, D.E. Stover, M.B. Zaman, E.M. Bernard, D.A. White.
Aerosolized pentamidine: effect on diagnosis and presentation of Pneumocvstis carinii pneumonia.
Ann Intern Med, 112 (1990), pp. 750-757
[88.]
M.I. Baskin, A.G. Abd, J.S. Ilowite.
Regional deposition of aerosolized pentamidine. Effects of body position and breathing pattern.
Ann Intern Med, 113 (1990), pp. 677-683
[89.]
K.A. Sepkowitz, E.E. Telzak, J.W.M. Gold, E.M. Bernard, S. Blum, M. Carrow, et al.
Pneumothorax in AIDS.
Ann Intern Med, 114 (1991), pp. 455-459
[90.]
R.E. Schoeffel, S.D. Anderson, R.E.C. Altounyan.
Bronchial hyperreactivity in response to inhalation of ultrasonically nebulized Solutions of distilled water and saline.
Br Med J, 283 (1981), pp. 1.285-1.287
[91.]
L.P. Boulet, C. Legris, L. Thibault, H. Turcotte.
Comparative bronchial responses to hyperosmolar saline and methacholine in asthma.
Thorax, 42 (1987), pp. 953-958
[92.]
M.S. Zach.
Antibiotic treatment, aerosol therapy: discussion.
Chest, 94 (1988), pp. 160-161
[93.]
T.G. O’Riordan, G.C. Smaldone.
Exposure of health care workers to aerosolized pentamidine.
Chest, 101 (1992), pp. 1.494-1.499
[94.]
J.R. Balines, Estacio Pl, P. Quinlan, T. Kelly, K. Corkery, P. Blanc.
Respiratory effects of occupational exposure to aerosolized pentamidine.
J Occup Environ Med, 37 (1995), pp. 145-150
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