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    "titulo" => "Valoracion de clenbuterol en la enfermedad pulmonar obstructiva cronica descompensada"
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            "nombre" => "M."
            "apellidos" => "de Frutos Herranz"
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        "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">In the patients diagnosed as having chronic obstructive pulmonary disease in phase of decompensation and submitted to mechanical ventilation with a Bird Mark-8 respirator at fixed pressure limit&#44; the authors have evaluated the efficacy of a preferential &#946;<span class="elsevierStyleInf">2</span> sympathomimetic&#44; clenbuterol&#46; According to the parameters controlled&#44; the respiratory volume per minute increased&#44; evaluated as an &#237;ndex of bronchodilatation&#44; the systemic and pulmonary arterial pressures were reduced in a way only slightly evaluatable&#44; while the effect &#40;f&#44; investigated&#44; according to the modif&#237;cations of cardiac frequency and of an &#237;ndex of contractility&#44; the phase of pre-ejection&#44; must be considered to be very scarce&#46; Controls of variation of the pulmonary venous admission &#40;Q<span class="elsevierStyleInf">va</span>&#47;Q<span class="elsevierStyleInf">t</span>&#41; and on the quotient ventilation&#47;perfusion &#40;V<span class="elsevierStyleInf">A</span>&#47;Q&#41; indicated that the alterations of contact between air flows and pulmonary blood flows&#44; that existed previously in patients suffering from this pathology&#44; were not aggravated&#46;</p></span>"
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Vol. 15. Issue 3.
Pages 132-136 (July - September 1979)
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Vol. 15. Issue 3.
Pages 132-136 (July - September 1979)
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Valoracion de clenbuterol en la enfermedad pulmonar obstructiva cronica descompensada
Evaluation of clenbuterol in decompesated chronic obstructive pulmonary disease
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M. de Frutos Herranz, A. Montón Rodríguez, R. Giral Sanz, J.M. Ayuela Azcárate, L. Nuño Gil
Servicio de Cuidados Intensivos de la Residencia Sanitaria General Yogue. Burgos
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Resumen

En 10 pacientes diagnosticados de enfermedad pulmonar obstructiva crónica (E.P.O.C.), en fase de descompensación y sometidos a ventilación mecánica con respirador Bird Mark-8 a presión límite fija, se ha valorado la eficacia de un simpaticomimético |32 preferencial, clenbuterol. Según los parámetros controlados, aumenta el volumen minuto respiratorio, valorado como índice de broncodilatación, se reducen de forma poco valorable las presiones arteriales sistémica y pulmonar, mientras que el efecto β1, investigado según las modificaciones de la frecuencia cardiaca y de un índice de contractilidad, la fase de preeyección (F.P.E.), debe considerarse muy escaso. Los controles efectuados sobre la variación de la admisión venosa pulmonar (Qva/Qt y sobre el cociente ventilación/perfusión (VA/Q) informan de que las alteraciones de contacto entre los flujos aéreo y sanguíneo pulmonares, previamente existentes en los enfermos afectos de esta patología, no se agravan.

Summary

In the patients diagnosed as having chronic obstructive pulmonary disease in phase of decompensation and submitted to mechanical ventilation with a Bird Mark-8 respirator at fixed pressure limit, the authors have evaluated the efficacy of a preferential β2 sympathomimetic, clenbuterol. According to the parameters controlled, the respiratory volume per minute increased, evaluated as an índex of bronchodilatation, the systemic and pulmonary arterial pressures were reduced in a way only slightly evaluatable, while the effect (f, investigated, according to the modifícations of cardiac frequency and of an índex of contractility, the phase of pre-ejection, must be considered to be very scarce. Controls of variation of the pulmonary venous admission (Qva/Qt) and on the quotient ventilation/perfusion (VA/Q) indicated that the alterations of contact between air flows and pulmonary blood flows, that existed previously in patients suffering from this pathology, were not aggravated.

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The AaDO2 and venous admixture at varying inspired oxygen concentrations in chronic obstructive pulmonary disease.
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Perfomances des systémes de dilution air-oxygène de quelques apareils de ventilation artificielle.
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Estudio comparativo de la concentración de oxygeno liberado por respiradores Benett PR-2 y Bird Mark-8.
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The use of central venous oxygen saturation measurements in a coronary care unit.
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M.N. Scheinman, M.A. Brown, E. Rappaport.
Critical assessment of use of central venous oxigen saturation as a mirror of mixed venous oxigen in severely ill patients.
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Reliability of central venous blood for calculating pulmonary shunts.
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Correlación entre la saturación de oxígeno en la sangre de la aurícula derecha y en sangre de la arteria pulmonar.
Rev. Clin. Esp., 140 (1976), pp. 125
Copyright © 1979. Sociedad Española de Neumología y Cirugía Torácica
Archivos de Bronconeumología
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