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Vol. 37. Issue 1.
Pages 48-50 (January 2001)
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Vol. 37. Issue 1.
Pages 48-50 (January 2001)
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Tratamiento del asma con antileucotrienos y síndrome de Churg-Strauss
Asthma treated with antileukotriene and Churg-Strauss syndrome
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J. Sala Félix*, M.E. Pereiro Alonso
Servicio de Neumología II. Hospital Central de Asturias. Oviedo
C. Salas Antón*
* Servicio de Anatomía Patológica. Hospital Puerta de Hierro. Madrid
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Desde la introducción de los antileucotrienos (ALT) en el tratamiento del asma existe controversia sobre si su uso pue-de dar lugar a un síndrome de Churg-Strauss (SCS) o si esta enfermedad simplemente se mantiene cohibida por el uso de esteroides, habiéndose publicado varios artículos en este sentido.

Presentamos el caso de un paciente con sospecha clínic de SCS con manifestaciones broncopulmonares, cutáneas y hematológicas, tratado con esteroides orales. Un año des-pués, tras su mejoría clínica, se sustituyó el tratamiento con esteroides orales por ALT, desarrollándose de nuevo la clí-nica y confirmándose anatomopatológicamente la vasculitis de Churg-Strauss.

Palabras clave:
Síndrome de Churg-Strauss
Asma
Antileuco-trienos
Esteroides

Since antileukotriene treatment for asthma was introdu-ced, there has been debate about whether such therapy can lead to Churg-Strauss Syndrome (CSS) or whether CSS is simply inhibited by the use of steroids, as various authors have suggested.

We report a case in which we suspected CSS in a patient with bronchopulmonary, cutaneous and analytical signs and whom we treated with oral steroids. After clinical improve-ment, one year later, steroids were replaced by antileukotrie-nes, after which the same clinical picture developed. The vas-culitis characteristic of CSS was confirmed pathologically.

Keywords:
Churg-Strauss syndrome
Asthma
Anti-leukotrienes
Steroids
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Copyright © 2001. Sociedad Española de Neumología y Cirugía Torácica
Archivos de Bronconeumología
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