array:23 [ "pii" => "S0300289624001728" "issn" => "03002896" "doi" => "10.1016/j.arbres.2024.05.011" "estado" => "S300" "fechaPublicacion" => "2024-10-01" "aid" => "3569" "copyright" => "SEPAR" "copyrightAnyo" => "2024" "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Arch Bronconeumol. 2024;60:664-5" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "itemSiguiente" => array:18 [ "pii" => "S0300289624001753" "issn" => "03002896" "doi" => "10.1016/j.arbres.2024.05.014" "estado" => "S300" "fechaPublicacion" => "2024-10-01" "aid" => "3572" "copyright" => "SEPAR" "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Arch Bronconeumol. 2024;60:666-7" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "en" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Clinical Image</span>" "titulo" => "Endobronchial Hamartoma Resected by Flexible Bronchoscopy: A Complex Approach" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "666" "paginaFinal" => "667" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1395 "Ancho" => 2000 "Tamanyo" => 359268 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">(A and B) Initial chest computed tomography revealing a lesion (red arrow) at the left main bronchial bifurcation; (C) air entrapment observed in the left lung during expiratory phase in chest computed tomography; (D) endoscopic view of the left main bronchus; (E) bronchial repermeabilization process using cryoablation and argon-plasma coagulation by flexible bronchoscopy; (F) endoscopic view of the left main bronchus after endoscopic resection; (G) endoscopic view inside left b6 segment showing a small remaining lesion (yellow arrow) at a b6 subdivision; (H) chest computed tomography follow-up, 1 month after endoscopic resection, identifying a residual endobronchial lesion (red arrow) at the left b6 segment; (I) endoscopic view of left b6 segment showing a growing lesion (yellow arrow), 2 months after endoscopic resection; (J) endoscopic view inside left b6 segment after the second endoscopic treatment; (K) endoscopic view of left b6 segment, 3 months after the first resection.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Joana Lourenço, Luís Rodrigues, Paulo Matos, Michele Santis, Amélia Estevão, Lourdes Barradas" "autores" => array:6 [ 0 => array:2 [ "nombre" => "Joana" "apellidos" => "Lourenço" ] 1 => array:2 [ "nombre" => "Luís" "apellidos" => "Rodrigues" ] 2 => array:2 [ "nombre" => "Paulo" "apellidos" => "Matos" ] 3 => array:2 [ "nombre" => "Michele" "apellidos" => "Santis" ] 4 => array:2 [ "nombre" => "Amélia" "apellidos" => "Estevão" ] 5 => array:2 [ "nombre" => "Lourdes" "apellidos" => "Barradas" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289624001753?idApp=UINPBA00003Z" "url" => "/03002896/0000006000000010/v1_202410020659/S0300289624001753/v1_202410020659/en/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S0300289624002308" "issn" => "03002896" "doi" => "10.1016/j.arbres.2024.06.010" "estado" => "S300" "fechaPublicacion" => "2024-10-01" "aid" => "3605" "copyright" => "SEPAR" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "crp" "cita" => "Arch Bronconeumol. 2024;60:662-3" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "en" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Clinical Letter</span>" "titulo" => "Right Adrenal Metastasis of Lung Cancer Diagnosed via Endoscopic Ultrasound (EUS-B) by a Pulmonologist" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "662" "paginaFinal" => "663" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1647 "Ancho" => 2467 "Tamanyo" => 397561 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">(A) Coronal PET scan: mediastinal mass, right (thick arrow) and left adrenal (thin arrow). (B) and (C) Right adrenal gland (thick arrow) in axial PET scan (B) and EUS-B (C). (D) and (E) Left adrenal gland (thin arrow) in axial PET scan (D) and EUS-B (E).</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Juan Cascón-Hernández, Javier López-García, Imane Saidi" "autores" => array:3 [ 0 => array:2 [ "nombre" => "Juan" "apellidos" => "Cascón-Hernández" ] 1 => array:2 [ "nombre" => "Javier" "apellidos" => "López-García" ] 2 => array:2 [ "nombre" => "Imane" "apellidos" => "Saidi" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289624002308?idApp=UINPBA00003Z" "url" => "/03002896/0000006000000010/v1_202410020659/S0300289624002308/v1_202410020659/en/main.assets" ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Clinical Image</span>" "titulo" => "Sometimes it's What it Doesn’t Look Like: Atypical Dissemination of Lung Adenocarcinoma" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "664" "paginaFinal" => "665" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Miguel Jiménez-Gómez, Ignacio Alba-de-Cáceres, José Ignacio de-Granda-Orive" "autores" => array:3 [ 0 => array:4 [ "nombre" => "Miguel" "apellidos" => "Jiménez-Gómez" "email" => array:1 [ 0 => "migueljimenezgomez@gmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "Ignacio" "apellidos" => "Alba-de-Cáceres" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "José Ignacio" "apellidos" => "de-Granda-Orive" "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff0015" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Pulmonology Department, 12th of October University Hospital, Madrid, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Radiology Department, 12th of October University Hospital, Madrid, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] 2 => array:3 [ "entidad" => "Medicine Department, Complutense University of Madrid, Spain" "etiqueta" => "c" "identificador" => "aff0015" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 3573 "Ancho" => 2510 "Tamanyo" => 888191 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Clinical case images: chest X-ray, computed tomography scan and positron emission tomography/computed tomography. Posteroanterior (A) and lateral (B) chest X-ray with bilateral nodular pattern. Chest computed tomography showing the lung mass (asterisk) in left lower lobe (coronal (C) and axial (E) views) with multiple bilateral ground-glass nodules, with a tendency to cavitation better defined in lower lobes (lateral view (D)). Fluorine-18 fluorodeoxyglucose positron emission tomography (E) with pathologic increased uptake in the mass, with unspecific low generalized metabolic activity.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">71-Year-old woman, never smoker, with no significant medical or family history. She presented with asthenia and progressive dyspnea of subacute onset to modified Medical Research Council grade 3. She had bilateral pulmonary pseudo-nodular pattern on chest X-ray (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>A and B), not present two years before. No relevant exposures or autoimmunity symptoms were identified. Room air oxygen saturation was 95%, without clubbing or crackles on chest exam. High-resolution chest computed tomography (CT) scan showed a left subpleural lung mass in the left lower lobe (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>C and E) with multiple bilateral ground-glass nodular opacities (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>D), without enlarged mediastinal lymph nodes. A fluorine-18 fluorodeoxyglucose positron emission tomography/CT revealed pathological increased uptake in the mass and unspecific low generalized activity, ruling out distant metastatic activity (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>F). A CT-guided transthoracic biopsy was diagnostic of adenocarcinoma with acinar growth pattern according to 2021 World Health Organization classification.<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">1</span></a> Next sequencing generation found epidermal growth factor exon 19 deletion, without PDL-1 expression on immunohistochemistry. She was referred to Oncology to consider systemic treatment. This is an uncommon presentation of metastatic lung adenocarcinoma, given the broad differential diagnosis of multiple nodular images in the absence of clear identifiable lung mass in the X-ray.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Funding</span><p id="par0010" class="elsevierStylePara elsevierViewall">This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Conflicts of interest</span><p id="par0015" class="elsevierStylePara elsevierViewall">The authors declare not to have any conflicts of interest that may be considered to influence directly or indirectly the content of the manuscript.</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Artificial intelligence involvement</span><p id="par0020" class="elsevierStylePara elsevierViewall">Not used.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:4 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Funding" ] 1 => array:2 [ "identificador" => "sec0010" "titulo" => "Conflicts of interest" ] 2 => array:2 [ "identificador" => "sec0015" "titulo" => "Artificial intelligence involvement" ] 3 => array:1 [ "titulo" => "Reference" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "multimedia" => array:1 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 3573 "Ancho" => 2510 "Tamanyo" => 888191 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Clinical case images: chest X-ray, computed tomography scan and positron emission tomography/computed tomography. Posteroanterior (A) and lateral (B) chest X-ray with bilateral nodular pattern. Chest computed tomography showing the lung mass (asterisk) in left lower lobe (coronal (C) and axial (E) views) with multiple bilateral ground-glass nodules, with a tendency to cavitation better defined in lower lobes (lateral view (D)). Fluorine-18 fluorodeoxyglucose positron emission tomography (E) with pathologic increased uptake in the mass, with unspecific low generalized metabolic activity.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "Reference" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0015" "bibliografiaReferencia" => array:1 [ 0 => array:3 [ "identificador" => "bib0010" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The 2021 WHO Classification of Lung Tumors: impact of advances since 2015" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "A.G. Nicholson" 1 => "M.S. Tsao" 2 => "M.B. Beasley" 3 => "A.C. Borczuk" 4 => "E. Brambilla" 5 => "W.A. Cooper" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.jtho.2021.11.003" "Revista" => array:6 [ "tituloSerie" => "J Thorac Oncol" "fecha" => "2022" "volumen" => "17" "paginaInicial" => "362" "paginaFinal" => "387" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/34808341" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/03002896/0000006000000010/v1_202410020659/S0300289624001728/v1_202410020659/en/main.assets" "Apartado" => array:4 [ "identificador" => "98298" "tipo" => "SECCION" "es" => array:2 [ "titulo" => "Cllinical Images" "idiomaDefecto" => true ] "idiomaDefecto" => "es" ] "PDF" => "https://static.elsevier.es/multimedia/03002896/0000006000000010/v1_202410020659/S0300289624001728/v1_202410020659/en/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289624001728?idApp=UINPBA00003Z" ]
Journal Information
Vol. 60. Issue 10.
Pages 664-665 (October 2024)
Vol. 60. Issue 10.
Pages 664-665 (October 2024)
Clinical Image
Sometimes it's What it Doesn’t Look Like: Atypical Dissemination of Lung Adenocarcinoma
Visits
835
This item has received
Article information
These are the options to access the full texts of the publication Archivos de Bronconeumología