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                        0 => array:2 [
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                            2 => "R Linnoila"
                            3 => "M Koss"
                            4 => "W Travis"
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                        "tituloSerie" => "Am J Surg Pathol"
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                        "paginaFinal" => "916"
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                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Surg Pathol"
                        "fecha" => "1980"
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                        "paginaInicial" => "343"
                        "paginaFinal" => "356"
                        "link" => array:1 [
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                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6252791"
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                      "autores" => array:1 [
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                          "autores" => array:6 [
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                            1 => "C Garc&#237;a"
                            2 => "V Herreros"
                            3 => "A Hern&#225;ndez"
                            4 => "M Mart&#237;n"
                            5 => "H &#193;lvarez"
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                      "Revista" => array:5 [
                        "tituloSerie" => "Rev Esp Patol"
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                        "paginaFinal" => "34"
                      ]
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                  ]
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                          "autores" => array:6 [
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                            2 => "H Ning"
                            3 => "Z Shu-Guang"
                            4 => "L Hong-Fen"
                            5 => "W Shu-Qin"
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                      "Revista" => array:5 [
                        "tituloSerie" => "Am J Surg Pathol"
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                        "paginaFinal" => "1022"
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                            5 => "J Ahn"
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                        ]
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                      "Revista" => array:6 [
                        "tituloSerie" => "J Comput Assist Tomogr"
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                        "paginaFinal" => "38"
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Vol. 43. Issue 7.
Pages 418-420 (January 2007)
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Vol. 43. Issue 7.
Pages 418-420 (January 2007)
Case Report
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Pulmonary Sclerosing Hemangioma in a Patient With Cowden Syndrome
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Félix Guerra-Gutiérreza,
Corresponding author
flaguers@hotmail.com

Correspondence: Dr. F.J. Álvarez-Gutiérrez. Servicio de Radiología. Hospital Universitario La Paz. Pº. de la Castellana, 261. 28046 Madrid. España
, Isabel Torres Sáncheza, Guillermo Gallardo-Madueñoa, Adrián Mariño-Enríquezb, Manuel Nistralb
a Servicio de Radiodiagnóstico, Hospital Universitario La Paz, Madrid, Spain
b Servicio de Anatomía Patológica, Hospital Universitario La Paz, Madrid, Spain
Related content
Arch Bronconeumol. 2007;43:64110.1016/S1579-2129(07)60147-5
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We describe the case of an 18-year-old female with Cowden syndrome in whom a simple x-ray detected a solitary pulmonary nodule that was identified as a sclerosing hemangioma. Pulmonary sclerosing hemangioma is an unusual lung neoplasm which typically presents as a solitary peripheral nodule in asymptomatic women. Although the histology of this entity is well defined, its origin and treatment is debated. One of the main diagnostic problems is to histologically differentiate a pulmonary sclerosing hemangioma from a papillary lung carcinoma.

Key words:
Sclerosing hemangioma
Lung tumor
Cowden syndrome

Describimos el caso de una paciente de 18 años con síndrome de Cowden, en quien una radiografía simple objetivó un nódulo pulmonar solitario que resultó ser un hemangioma esclerosante. El hemangioma esclerosante de pulmón es una neoplasia pulmonar poco frecuente, que suele presentarse como un nódulo solitario periférico en mujeres asintomáticas. En la actualidad, aunque la histología del hemangioma esclerosante está bien definida, son objeto de discusión la histiogénesis de esta entidad y su tratamiento. Uno de los principales problemas diagnósticos es diferenciar histológicamente el hemangioma esclerosante del adenocarcinoma pulmonar con patrón papilar.

Palabras clave:
Hemangioma esclerosante
Tumores de pulmón
Síndrome de Cowden
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REFERENCES
[1]
H Gonzalo Cardemil, P Eduardo Fernández, Paola Riffoc, O Diego Reyes, R Rodrigo Ledezma, O Magdalena Mira, et al.
Hemangioma esclerosante pulmonar como nódulo pulmonar solitario: comunicación de 1 caso.
Rev Med Chile, 132 (2004), pp. 853-856
[2]
M Devouassoux-Shisheboran, T Hayashi, R Linnoila, M Koss, W Travis.
A clinicopathologic study of 100 cases of pulmonary sclerosing hemangioma with immunohistochemical studies. TTF-1 is expressed in both round and surface cells, suggesting an origin from primitive respiratory epithelium.
Am J Surg Pathol, 24 (2000), pp. 906-916
[3]
E Fernández, C Merino, E Martínez.
Hemangioma esclerosante pulmonar: tumor de fácil confusión con el carcinoma broncogénico.
Arch Bronconeumol, 38 (2002), pp. 458-459
[4]
A Iyoda, M Baba, H Saitoh, H Hoshino, K Shibuya, et al.
Imprint cytologic features of pulmonary sclerosing hemangioma. Comparison with well-differentiated papillary adenocarcinoma.
Cancer Cytopathology, 96 (2002), pp. 146-149
[5]
ALA Katzenstein, JT Gmelich, CB Carrington.
Sclerosing hemangioma of the lung. A clinicopathologic study of 51 cases.
Am J Surg Pathol, 4 (1980), pp. 343-356
[6]
C Manzano, C García, V Herreros, A Hernández, M Martín, H Álvarez, et al.
Diagnóstico citológico por punción aspiración del hemangioma esclerosante pulmonar o neumocitoma tipo II: a propósito de tres casos.
Rev Esp Patol, 32 (1999), pp. 27-34
[7]
X Hong-Min, L Wei-Hua, H Ning, Z Shu-Guang, L Hong-Fen, W Shu-Qin, et al.
Neuroendocrine differentiation in 32 cases of so called sclerosing hemangioma of the lung: identified by immunohistochemical and ultrastructural study.
Am J Surg Pathol, 219 (1997), pp. 1013-1022
[8]
J Im, W Kim, M Han, Y Han, J Chung, J Ahn, et al.
Sclerosing hemangiomas of the lung and interlobar fissures: CT findings.
J Comput Assist Tomogr, 18 (1994), pp. 34-38
[9]
R Pilarski, C Eng.
Will the real Cowden syndrome please stand up (again)? Expanding mutational and clinical spectra of the PTEN hamartoma tumor syndrome.
J Med Genet, 41 (2004), pp. 323-326
[10]
MM Turnbull, V Humeniuk, B Stein, GK Suthers.
Arteriovenous malformations in Cowden syndrome.
J Med Genet, 42 (2005), pp. e50
[11]
H Naoki, S Toshiya, A Katsutoshi, S Tomoaki, T Toshiro, M Yasuhiro, et al.
Pulmonary sclerosing hemangioma associated with familial adenomatous polyposis.
Hum Pathol, 35 (2004), pp. 764-768
[12]
S Rizzo, U Pandolfi, L Villani, G Terzuolo, P Cremaschi, M Benedetti, et al.
Pulmonary sclerosing hemangioma in a woman with multiple uterine fibromas, cysts to thyroid and kidney.
Anticancer Res, 16 (1996), pp. 1297-1300
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