Journal Information
Vol. 25. Issue 1.
Pages 28-30 (January - February 1989)
Share
Share
Download PDF
More article options
Vol. 25. Issue 1.
Pages 28-30 (January - February 1989)
Full text access
Neumonia lipoidea aspirativa
Lipoid aspiration pneumonia
Visits
4300
S. Romero Candeira, C. Martín Serrano, M. Palau Benavent, J. Tobías Ferrer, I. Aranda López, E. Escortell Mayor
Sección de Neumología (Servicio de Medicina Interna) y Servicio de Anatomía Patológica. Hospital de Alicante (S V S). Facultad de Medicina. Alicante
This item has received
Article information

La neumonía lipoidea aspirativa es una entidad referida infrecuentemente en la literatura actual y probablemente infradiagnosticada. Durante los tres últimos años se han diagnosticado en nuestra sección cuatro pacientes con neumonía lipoidea secundaria al uso prolongado de medicación tópica, con contenido graso, sobre vías aéreas superiores.

Las dificultades para su diagnóstico se derivan de la falta de expresión del contenido graso en muchos preparados tópicos, antiinflamatorios y vasoconstrictores, del aspecto radiológico del proceso, que puede simular al del carcinoma broncogénico y de la posibilidad que los cambios citológicos provocados por el aceite mineral aspirado se confundan con los de un proceso maligno.

Todos los casos aquí comunicados fueron confirmados histológicamente, siendo la biopsia transbronquial la que aportó la muestra diagnóstica en tres de ellos.

Lipoid aspiration pneumonia is an infrequently reported entity in relevant current literature which probably is underdiagnosed. During the last 3 years, four patients with lipoid aspiration pneumonia secondary to prolonged use of topical medication with oily content on upper airways have been diagnosed at our Section.

The diagnostic difficulties are derived from the lack of specification of the oily content in many topical preparations, such as vasoconstrictor and anti-inflammatory agents, from the radiologic appearance of the process, which may mimick a broncogenic carcinoma, and from the possibility of the cytologic changes caused by the mineral oil are mistaken for those caused by a malignant process.

All the cases we report were histologically confirmed, being the transbronchial biopsy the method which yielded the diagnostic sample in three of them.

Full text is only aviable in PDF
Bibliografía
[1.]
G.F. Laughlen.
Studies on pneumonía following nasopharyngeal injections of oil.
Amer J Path, 1 (1925), pp. 407-411
[2.]
J.D. Kennedy, P. Costello, J.P. Balikian, P.G. Herman.
Exogenous lipoid pneumonia.
AJR, 136 (1981), pp. 1145-1149
[3.]
C.A. Hales, E.J. Mark.
Case record of the Massachussetts General Hospital.
Case 19. N Engl J Med, 296 (1977), pp. 1105-1111
[4.]
J. Borrie, J.F. Gwyne.
Paraffinoma of lung: Lipoid pneumonía. Report of two cases.
Thorax, 28 (1973), pp. 214-221
[5.]
C.A. Ribaudo, W.J. Grace.
Pulmonary aspiration.
Am J Med, 50 (1971), pp. 510-520
[6.]
J.K. Lipinski, G.L. Weisbrod, D.E. Sanders.
Exogenous lipoid pneumonitis: Pulmonary patterns.
AJR, 136 (1981), pp. 931-934
[7.]
S.R. Bulmer, D. Lamb, R.J.M. Me Cormack, P.R. Walbaum.
Aetiology of unresolved pneumonia.
Thorax, 33 (1978), pp. 307-314
[8.]
P.S. Wheeler, F.P. Stitik, G.M. Hutchins, H.F. Klinefelter, S.S. Siegelman.
Diagnosis of lipoid pneumonia by computed tomography.
JAMA, 245 (1981), pp. 65-66
[9.]
R.R. Joshi, J.V. Cholankeril.
Computed tomography in lipoid pneumonía.
J Comput Assist Tomogr, 9 (1985), pp. 211-213
[10.]
G. Dongay, T. Levade, A. Caratero, R. Salvayre, D. Lauque, P. Caries.
Etude biochimique et cytologique du liquide de lavage alveolaire dans 4 cas de pneumopathies huileuses.
Presse MEd, 15 (1986), pp. 1863-1868
[11.]
M. Spatafora, B. Bellia, G. Ferrara, G. Genova.
Diagnosis of a case of lipoid pneumonia by bronchoalveolar lavage.
Respiration, 52 (1987), pp. 154-156
[12.]
R.W. Corwin, R.S. Irwin.
The lipid-laden alveolar macrophage as a marker of aspiration in parenchymal lung disease.
Am Rev Respir Dis, 132 (1985), pp. 576-581
[13.]
J.L. Colombo, T.K. Hallberg.
Recurrent aspiration in children: lipid-laden alveolar macrophage quantitation.
Pediatr Pulmonol, 3 (1987), pp. 86-89
[14.]
K.M.A. Perry.
Lipoid pneumonía.
En: Perry-Holmes Sellors. Chest diseases. London Butterworths, (1963), pp. 75-77
[15.]
B. Felson, G. Ralaisomay.
Carcinoma of the lung complicating lipoid pneumonia.
AJR, 141 (1983), pp. 901-907
[16.]
J. Casademont, A. Xaubet, J. López Guillermo, C. Agustí, J. Ramírez.
Radiographic bilateral cavitary lesions in lipoid pneumonia.
Eur Respir J, 1 (1988), pp. 93-94
[17.]
L.F. Ayvazian, D.S. Steward, C.G. Merkel, W.W. Frederich.
Diffuse lipoid pneumonitis succesfully treated with prednisone.
Am J. Med, 43 (1967), pp. 930-933
[18.]
D. Oidenburger, W.J. Maurer, E. Beltaos, G.E. Magnin.
Inhaladon lipoid pneumonía from burning fats. A newly recognized industrial hazard.
JAMA, 222 (1972), pp. 1288-1289
Copyright © 1989. Sociedad Española de Neumología y Cirugía Torácica
Archivos de Bronconeumología
Article options
Tools

Are you a health professional able to prescribe or dispense drugs?