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            2 => "Neumon&#237;a at&#237;pica"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">Estudiar la evoluci&#243;n de un grupo de neumon&#237;as extrahospitalarias causadas por g&#233;rmenes at&#237;picos &#40;<span class="elsevierStyleItalic">Mycoplasma pneumoniae&#44; Legionella spp&#46;&#44; Coxiella burnetii y Chlamydophila pneumoniae</span>&#41; en funci&#243;n del tratamiento emp&#237;rico recibido&#46;</p> <span class="elsevierStyleSectionTitle">Pacientes y m&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">Entre enero de 1996 y febrero de 2001 ingresaron en nuestra unidad 390 casos de neumon&#237;a&#44; de los que 89 estaban causados por g&#233;rmenes at&#237;picos&#46; Los pacientes se dividieron retrospectivamente en 2 grupos seg&#250;n el tratamiento emp&#237;rico pautado&#58; grupo A&#44; al que se hab&#237;a proporcionado cobertura frente a g&#233;rmenes at&#237;picos &#40;quinolonas o macr&#243;lidos&#41;&#44; y grupo B&#44; al que no se hab&#237;a proporcionado dicha cobertura&#46; Se estudi&#243; la evoluci&#243;n seg&#250;n las diferencias entre ambos grupos en la estancia hospitalaria&#44; la resoluci&#243;n radiol&#243;gica&#44; el reingreso en el primer mes tras el alta y la mortalidad&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">El grupo de estudio lo constituyeron 89 pacientes con neumon&#237;a causada por g&#233;rmenes at&#237;picos &#40;39 en el grupo A y 50 en el B&#41;&#46; Las variables estudiadas no mostraron diferencias significativas entre ambos grupos&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">En nuestra serie de neumon&#237;as extrahospitalarias la cobertura antibi&#243;tica frente a g&#233;rmenes at&#237;picos no mejor&#243; la evoluci&#243;n cl&#237;nica y radiol&#243;gica de los pacientes&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">To study the course of disease and outcomes in a group of patients with community-acquired pneumonia caused by atypical pathogens &#40;<span class="elsevierStyleItalic">Mycoplasma pneumoniae&#44; Legionella species&#44; Coxiella burnetii&#44; and Chlamydophila pneumoniae</span>&#41; according to the empiric treatment received&#46;</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p class="elsevierStyleSimplePara elsevierViewall">Of a total of 390 patients admitted to our hospital with pneumonia between January 1996 and February 2001&#44; the causative microorganism was an atypical pathogen in 89 cases&#46; Patients were divided retrospectively into 2 groups according to the empiric treatment they received&#58; group A&#44; who had received an antibiotic regime &#40;quinolones or macrolides&#41; that provided coverage for atypical pathogens&#59; and group B&#44; who had received treatment that did not provide such coverage&#46; Clinical course was assessed in terms of the differences between the 2 groups in length of hospital stay&#44; radiographic resolution&#44; readmission at 30 days after discharge&#44; and mortality&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">A total of 89 patients with pneumonia caused by atypical pathogens &#40;39 in group A and 50 in group B&#41; were studied&#46; No significant between-group differences in the variables were found&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">In this group of patients hospitalized for community-acquired pneumonia&#44; antibiotic regimens providing coverage for atypical pathogens did not improve either clinical or radiographic evolution&#46;</p>"
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                        "paginaFinal" => "246"
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              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Deaths in risk classes I-III&#58; a measure of quality of care in patients hospitalised with CAP&#63;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "T&#46;J&#46; Marrie"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur Respir J"
                        "fecha" => "2004"
                        "volumen" => "23"
                        "paginaInicial" => "103"
                        "paginaFinal" => "105"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14738240"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib10"
              "etiqueta" => "10&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Effect of macrolides as part of initial empiric therapy on length of stay in patients hospitalized with community-acquired pneumonia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "J&#46;A&#46; Stahl"
                            1 => "M&#46; Barza"
                            2 => "J&#46; DesJardin"
                            3 => "R&#46; Martin"
                            4 => "M&#46;H&#46; Eckman"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Arch Inter Med"
                        "fecha" => "1999"
                        "volumen" => "159"
                        "paginaInicial" => "2576"
                        "paginaFinal" => "2580"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib11"
              "etiqueta" => "11&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Associations between initial antimicrobial therapy and medical outcomes for hospitalized elderly patients with pneumonia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "P&#46;P&#46; Gleason"
                            1 => "T&#46;P&#46; Meehan"
                            2 => "J&#46;M&#46; Fine"
                            3 => "D&#46;H&#46; Galusha"
                            4 => "M&#46;J&#46; Fine"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Intern Med"
                        "fecha" => "1999"
                        "volumen" => "159"
                        "paginaInicial" => "2562"
                        "paginaFinal" => "2572"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10573046"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib12"
              "etiqueta" => "12&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Neumon&#237;a adquirida en la comunidad&#58; influencia de la duraci&#243;n de la antibioterapia intravenosa en la estancia hospitalaria y relaci&#243;n coste&#47;efectividad"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "R&#46; Fern&#225;ndez"
                            1 => "J&#46;A&#46; Gull&#243;n"
                            2 => "G&#46; Rubinos"
                            3 => "A&#46; Jim&#233;nez"
                            4 => "A&#46; Medina"
                            5 => "C&#46; Hern&#225;ndez"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Bronconeumol"
                        "fecha" => "2001"
                        "volumen" => "37"
                        "paginaInicial" => "366"
                        "paginaFinal" => "370"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11674935"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib13"
              "etiqueta" => "13&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pacientes ingresados por neumon&#237;a adquirida en la comunidad&#58; estudio comparativo en funci&#243;n de la especialidad del servicio m&#233;dico responsable"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "A&#46; Capelastegui"
                            1 => "P&#46;P&#46; Espa&#241;a"
                            2 => "J&#46;M&#46; Quintana"
                            3 => "I&#46; Gorordo"
                            4 => "A&#46; Mart&#237;nez Urquiri"
                            5 => "I&#46; Idoiaga"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Bronconeumol"
                        "fecha" => "2005"
                        "volumen" => "41"
                        "paginaInicial" => "300"
                        "paginaFinal" => "306"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15989886"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib14"
              "etiqueta" => "14&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Neumon&#237;a&#58; predecir la mala evoluci&#243;n"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "R&#46; Men&#233;ndez"
                            1 => "A&#46; Torres"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Bronconeumol"
                        "fecha" => "2005"
                        "volumen" => "41"
                        "paginaInicial" => "475"
                        "paginaFinal" => "477"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16194508"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib15"
              "etiqueta" => "15&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Implications for macrolide treatment in community-acquired pneumonia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "L&#46;M&#46; Mundy"
                            1 => "D&#46; Oldach"
                            2 => "P&#46;G&#46; Auwaerter"
                            3 => "C&#46;A&#46; Gaydos"
                            4 => "R&#46;D&#46; Moore"
                            5 => "J&#46;G&#46; Bartlett"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Chest"
                        "fecha" => "1998"
                        "volumen" => "113"
                        "paginaInicial" => "1201"
                        "paginaFinal" => "1206"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib16"
              "etiqueta" => "16&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Which atypical pneumonia&#63;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "K&#46; Barton"
                            1 => "D&#46;P&#46; Nicholls"
                            2 => "C&#46;F&#46; Stanford"
                            3 => "J&#46;H&#46; Connolly"
                            4 => "T&#46;S&#46; Wilson"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Infect"
                        "fecha" => "1989"
                        "volumen" => "19"
                        "paginaInicial" => "294"
                        "paginaFinal" => "297"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2600450"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib17"
              "etiqueta" => "17&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Immunomodulatory activity and effectiveness of macrolides in chronic airway disease"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "B&#46;K&#46; Rubin"
                            1 => "M&#46;O&#46; Henke"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "2004"
                        "volumen" => "125"
                        "numero" => "Suppl"
                        "paginaInicial" => "70"
                        "paginaFinal" => "78"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib18"
              "etiqueta" => "18&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Combination antibiotic therapy lowers mortality among severely ill patients with pneumococcal bacteremia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "L&#46;M&#46; Baddour"
                            1 => "V&#46;L&#46; Yu"
                            2 => "K&#46;P&#46; Klugman"
                            3 => "C&#46; Feldman"
                            4 => "A&#46; Ortqvist"
                            5 => "J&#46; Rello"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1164/rccm.200311-1578OC"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Respir Crit Care Med"
                        "fecha" => "2004"
                        "volumen" => "170"
                        "paginaInicial" => "440"
                        "paginaFinal" => "444"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15184200"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib19"
              "etiqueta" => "19&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Community-acquired pneumonia in Europe&#58; causative pathogens and resistance patterns"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "M&#46; Woodhead"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Eur Respir J"
                        "fecha" => "2002"
                        "volumen" => "20"
                        "numero" => "Suppl 36"
                        "paginaInicial" => "20"
                        "paginaFinal" => "27"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12166571"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib20"
              "etiqueta" => "20&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Effectiveness of beta-lactam antibiotics compared with antibiotics active against atypical pathogens in non-severe community acquired pneumonia&#58; meta-analysis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "G&#46;D&#46; Mills"
                            1 => "M&#46;R&#46; Oehley"
                            2 => "B&#46; Arrol"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1136/bmj.38334.591586.82"
                      "Revista" => array:6 [
                        "tituloSerie" => "BMJ"
                        "fecha" => "2005"
                        "volumen" => "330"
                        "paginaInicial" => "456"
                        "paginaFinal" => "462"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15684024"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bib21"
              "etiqueta" => "21&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Role of beta-lactam agents in the treatment of community-acquired pneumonia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "J&#46; Garau"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s10096-005-1287-9"
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur J Clin Microbiol Infect Dis"
                        "fecha" => "2005"
                        "volumen" => "24"
                        "paginaInicial" => "83"
                        "paginaFinal" => "99"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15696306"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            21 => array:3 [
              "identificador" => "bib22"
              "etiqueta" => "22&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "&#193;rea de Tuberculosis e Infecciones Respiratorias &#40;TIR&#41;&#46; Normativa para el diagn&#243;stico y tratamiento de la neumon&#237;a adquirida en la comunidad"
                      "autores" => array:1 [
                        0 => array:2 [
                          "colaboracion" => "Grupo de Estudio de la Neumon&#237;a Adquirida en la Comunidad"
                          "etal" => false
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Bronconeumol"
                        "fecha" => "2005"
                        "volumen" => "41"
                        "paginaInicial" => "272"
                        "paginaFinal" => "289"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15919009"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
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Vol. 42. Issue 9.
Pages 430-433 (September 2006)
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Vol. 42. Issue 9.
Pages 430-433 (September 2006)
Originales
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Neumonía adquirida en la comunidad por gérmenes atípicos: tratamiento y evolución
Treatment and Course of Community-Acquired Pneumonia Caused by Atypical Pathogens
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Ramón Fernández Álvarez
Corresponding author
enelllano@terra.es

Correspondencia: Dr. R. Fernández Álvarez. San Juan Bautista, 19, A. 38002 Santa Cruz de Tenerife. España.
, Isabel Suárez Toste, Gemma Rubinos Cuadrado, Agustín Medina Gonzálvez, José Antonio Gullón Blanco, Isidro González Martín
Servicio de Neumología. Hospital Universitario de Canarias. La Laguna. Santa Cruz de Tenerife. España
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Abstract
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Objetivo

Estudiar la evolución de un grupo de neumonías extrahospitalarias causadas por gérmenes atípicos (Mycoplasma pneumoniae, Legionella spp., Coxiella burnetii y Chlamydophila pneumoniae) en función del tratamiento empírico recibido.

Pacientes y métodos

Entre enero de 1996 y febrero de 2001 ingresaron en nuestra unidad 390 casos de neumonía, de los que 89 estaban causados por gérmenes atípicos. Los pacientes se dividieron retrospectivamente en 2 grupos según el tratamiento empírico pautado: grupo A, al que se había proporcionado cobertura frente a gérmenes atípicos (quinolonas o macrólidos), y grupo B, al que no se había proporcionado dicha cobertura. Se estudió la evolución según las diferencias entre ambos grupos en la estancia hospitalaria, la resolución radiológica, el reingreso en el primer mes tras el alta y la mortalidad.

Resultados

El grupo de estudio lo constituyeron 89 pacientes con neumonía causada por gérmenes atípicos (39 en el grupo A y 50 en el B). Las variables estudiadas no mostraron diferencias significativas entre ambos grupos.

Conclusiones

En nuestra serie de neumonías extrahospitalarias la cobertura antibiótica frente a gérmenes atípicos no mejoró la evolución clínica y radiológica de los pacientes.

Palabras clave:
Tratamiento antibiótico de la neumonía
Neumonía adquirida en la comunidad
Neumonía atípica
Objective

To study the course of disease and outcomes in a group of patients with community-acquired pneumonia caused by atypical pathogens (Mycoplasma pneumoniae, Legionella species, Coxiella burnetii, and Chlamydophila pneumoniae) according to the empiric treatment received.

Patients and methods

Of a total of 390 patients admitted to our hospital with pneumonia between January 1996 and February 2001, the causative microorganism was an atypical pathogen in 89 cases. Patients were divided retrospectively into 2 groups according to the empiric treatment they received: group A, who had received an antibiotic regime (quinolones or macrolides) that provided coverage for atypical pathogens; and group B, who had received treatment that did not provide such coverage. Clinical course was assessed in terms of the differences between the 2 groups in length of hospital stay, radiographic resolution, readmission at 30 days after discharge, and mortality.

Results

A total of 89 patients with pneumonia caused by atypical pathogens (39 in group A and 50 in group B) were studied. No significant between-group differences in the variables were found.

Conclusions

In this group of patients hospitalized for community-acquired pneumonia, antibiotic regimens providing coverage for atypical pathogens did not improve either clinical or radiographic evolution.

Key words:
Antibiotic treatment for pneumonia
Community-acquired pneumonia
Atypical pneumonia
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Bibliografía
[1.]
American Thoracic Society.
Guidelines for the management of adults with community-acquired pneumonia.
Am J Respir Crit Care Med, 163 (2001), pp. 1730-1754
[2.]
J. Dorca, S. Bello, J. Blanquer, R. De Cellis, L. Molinos, A. Torres, et al.
Diagnóstico y tratamiento de la neumonía adquirida en la comunidad.
Arch Bronconeumol, 33 (1997), pp. 240-246
[3.]
British Thoracic Society.
Guidelines for the management of community- acquired pneumonia in adults.
Thorax, 56 (2001), pp. 1-64
[4.]
Grupo de Trabajo de la Asociación Latinoamericana del Tórax (ALAT).
Actualización de las recomendaciones ALAT sobre la neumonía adquirida en la comunidad.
Arch Bronconeumol, 40 (2004), pp. 364-374
[5.]
A. Örtqvist.
Treatment of community-acquired lower respiratory tract infections in adults.
Eur Respir J, 36 (2002), pp. 40-53
[6.]
L. Molinos.
Importancia de la etiología polimicrobiana en la neumonía.
Arch Bronconeumol, 39 (2003), pp. 22-26
[7.]
T.M. File, J. Garau, F. Blasi, C. Chidiac, K. Klusman, H. Code, et al.
Guidelines for empiric antimicrobial prescribing in community acquired pneumonia.
Chest, 125 (2004), pp. 1888-1901
[8.]
M.J. Fine, T.E. Auble, D. Yealy, B.H. Hanusa, L.A. Weissfeld, D.E. Singer, et al.
A prediction rule to identify low-risk patients with community-acquired pneumonia.
N Engl J Med, 336 (1997), pp. 243-250
[9.]
T.J. Marrie.
Deaths in risk classes I-III: a measure of quality of care in patients hospitalised with CAP?.
Eur Respir J, 23 (2004), pp. 103-105
[10.]
J.A. Stahl, M. Barza, J. DesJardin, R. Martin, M.H. Eckman.
Effect of macrolides as part of initial empiric therapy on length of stay in patients hospitalized with community-acquired pneumonia.
Arch Inter Med, 159 (1999), pp. 2576-2580
[11.]
P.P. Gleason, T.P. Meehan, J.M. Fine, D.H. Galusha, M.J. Fine.
Associations between initial antimicrobial therapy and medical outcomes for hospitalized elderly patients with pneumonia.
Arch Intern Med, 159 (1999), pp. 2562-2572
[12.]
R. Fernández, J.A. Gullón, G. Rubinos, A. Jiménez, A. Medina, C. Hernández, et al.
Neumonía adquirida en la comunidad: influencia de la duración de la antibioterapia intravenosa en la estancia hospitalaria y relación coste/efectividad.
Arch Bronconeumol, 37 (2001), pp. 366-370
[13.]
A. Capelastegui, P.P. España, J.M. Quintana, I. Gorordo, A. Martínez Urquiri, I. Idoiaga, et al.
Pacientes ingresados por neumonía adquirida en la comunidad: estudio comparativo en función de la especialidad del servicio médico responsable.
Arch Bronconeumol, 41 (2005), pp. 300-306
[14.]
R. Menéndez, A. Torres.
Neumonía: predecir la mala evolución.
Arch Bronconeumol, 41 (2005), pp. 475-477
[15.]
L.M. Mundy, D. Oldach, P.G. Auwaerter, C.A. Gaydos, R.D. Moore, J.G. Bartlett, et al.
Implications for macrolide treatment in community-acquired pneumonia.
Chest, 113 (1998), pp. 1201-1206
[16.]
K. Barton, D.P. Nicholls, C.F. Stanford, J.H. Connolly, T.S. Wilson.
Which atypical pneumonia?.
J Infect, 19 (1989), pp. 294-297
[17.]
B.K. Rubin, M.O. Henke.
Immunomodulatory activity and effectiveness of macrolides in chronic airway disease.
Chest, 125 (2004), pp. 70-78
[18.]
L.M. Baddour, V.L. Yu, K.P. Klugman, C. Feldman, A. Ortqvist, J. Rello, et al.
Combination antibiotic therapy lowers mortality among severely ill patients with pneumococcal bacteremia.
Am J Respir Crit Care Med, 170 (2004), pp. 440-444
[19.]
M. Woodhead.
Community-acquired pneumonia in Europe: causative pathogens and resistance patterns.
Eur Respir J, 20 (2002), pp. 20-27
[20.]
G.D. Mills, M.R. Oehley, B. Arrol.
Effectiveness of beta-lactam antibiotics compared with antibiotics active against atypical pathogens in non-severe community acquired pneumonia: meta-analysis.
[21.]
J. Garau.
Role of beta-lactam agents in the treatment of community-acquired pneumonia.
Eur J Clin Microbiol Infect Dis, 24 (2005), pp. 83-99
[22.]
Grupo de Estudio de la Neumonía Adquirida en la Comunidad.
Área de Tuberculosis e Infecciones Respiratorias (TIR). Normativa para el diagnóstico y tratamiento de la neumonía adquirida en la comunidad.
Arch Bronconeumol, 41 (2005), pp. 272-289
Copyright © 2006. Sociedad Española de Neumología y Cirugía Torácica
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