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Vol. 46. Issue 9.
Pages 489-491 (July 2010)
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Vol. 46. Issue 9.
Pages 489-491 (July 2010)
Clinical Note
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Hard Metal Interstitial Lung Disease
Enfermedad pulmonar intersticial por metales duros
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M. Ángeles Monteroa,,
Corresponding author
mamontero@vhebron.net

Corresponding author.
, Javier de Graciab,, Ferràn Morellb
a Servicio de Anatomía Patológica, Hospital Universitario Vall d’Hebron, Barcelona, Spain
b Servicio de Neumología, Hospital Universitario Vall d’Hebron, Barcelona, Spain
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Abstract

Hard metal lung disease is an unusual disease which can occur in individuals exposed to hard metals. Clinically, the condition resembles hypersensitivity pneumonitis depending mainly on individual susceptibility, which eventually progresses to pulmonary fibrosis. We present two patients with pulmonary fibrosis, who were actually diagnosed after an exhaustive anamnesis and examination of the tissue by scanning microscope to discard hard metals. The evaluation of wedge biopsies by scanning electronic microscope can be very helpful in those cases without a specific diagnosis.

Keywords:
Hard metal
Interstitial lung disease
Pneumonitis
Resumen

La neumonitis por metales duros es una enfermedad infrecuente que aqueja a personas expuestas a polvo de metales duros. La presentación clínica es la de una neumonitis por hipersensibilidad y los pacientes pueden evolucionar a una fibrosis pulmonar, dependiendo probablemente de su susceptibilidad. Presentamos 2 casos correspondientes a 2 mujeres con fibrosis pulmonar. La anamnesis exhaustiva y el estudio del tejido de la biopsia para descartar la presencia de metales duros permitieron el diagnóstico de esta enfermedad. Se discute la utilidad de la biopsia para su valoración histológica y su estudio posterior con el microscopio electrónico de barrido.

Palabras clave:
Metales duros
Enfermedad intersticial pulmonar
Neumonitis
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The authors are members of the CIBER Respiratory Diseases Group, CIBERES.

Copyright © 2010. Sociedad Española de Neumología y Cirugía Torácica
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