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    "titulo" => "Factores que afectan al factor de transferencia para el co en el pulmon, con especial referencia a cambios en el volumen alveolar"
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        "resumen" => "<span id="absec0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Se ha realizado el test de transferencia para el CO &#40;difusi&#243;n&#41; en ocho sujetos sanos a diferentes vol&#250;menes alveolares&#46; En cuatro de ellos se realiz&#243; adem&#225;s la prueba en dec&#250;bito&#44; tras esfuerzo y a altos niveles de ox&#237;geno con el fin de fraccionarlo en Dm y Ve&#44; asimismo se realiz&#243; en &#233;stos el m&#233;todo de estado estable basal a FRC&#44; basal a distintos vol&#250;menes alveolares y durante el esfuerzo&#46;</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Se ha observado una relaci&#243;n lineal entre el TL y el Va&#44; sin variaciones en el volumen capilar pulmonar&#44; que no puede ser achacada a variaciones en el CO alveolar&#46; Los incrementos con el dec&#250;bito han sido inferiores a los del esfuerzo&#46;</p><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Gran parte de las diferencias entre los valores de los m&#233;todos SB y SS2 parecen ser debidas al distinto volumen alveolar al cual se realiza la prueba&#46;</p></span>"
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        "titulo" => "Summary"
        "resumen" => "<span id="absec0010" class="elsevierStyleSection elsevierViewall"><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">CO diffusion was tested in 8 apparently healthy subjects at different alveolar volumes&#46; Four were also tested in the supine position&#44; after excercise and at high oxygen levels&#44; to allow for Dm and Ve fractioning&#59; these same subjects were checked for FRC at stable basal level&#59; basal level at different alveolar volumen and during exertion&#46;</p><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">A lineal relationship between TL and Va&#44; without variations in capillary volume and which cannot be attributed to variations in alveolar CO&#44; was observed&#46;</p><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Many of the differences seen between the SB and SS<span class="elsevierStyleInf">2</span> methode seems due to the different alveolar volume at which these tests are done&#46;</p></span>"
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Journal Information
Vol. 18. Issue 3.
Pages 152-155 (May - June 1982)
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Vol. 18. Issue 3.
Pages 152-155 (May - June 1982)
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Factores que afectan al factor de transferencia para el co en el pulmon, con especial referencia a cambios en el volumen alveolar
Factors affecting the co transfer factors of the lung: a special reference to changes in alveolar volume
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10764
N. Gonzalez Mangado, F. Lahoz Navarro
Sección de Fisiopatología. Servicio de Respiratorio. Fundación Jiménez Díaz. Madrid
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Resumen

Se ha realizado el test de transferencia para el CO (difusión) en ocho sujetos sanos a diferentes volúmenes alveolares. En cuatro de ellos se realizó además la prueba en decúbito, tras esfuerzo y a altos niveles de oxígeno con el fin de fraccionarlo en Dm y Ve, asimismo se realizó en éstos el método de estado estable basal a FRC, basal a distintos volúmenes alveolares y durante el esfuerzo.

Se ha observado una relación lineal entre el TL y el Va, sin variaciones en el volumen capilar pulmonar, que no puede ser achacada a variaciones en el CO alveolar. Los incrementos con el decúbito han sido inferiores a los del esfuerzo.

Gran parte de las diferencias entre los valores de los métodos SB y SS2 parecen ser debidas al distinto volumen alveolar al cual se realiza la prueba.

Summary

CO diffusion was tested in 8 apparently healthy subjects at different alveolar volumes. Four were also tested in the supine position, after excercise and at high oxygen levels, to allow for Dm and Ve fractioning; these same subjects were checked for FRC at stable basal level; basal level at different alveolar volumen and during exertion.

A lineal relationship between TL and Va, without variations in capillary volume and which cannot be attributed to variations in alveolar CO, was observed.

Many of the differences seen between the SB and SS2 methode seems due to the different alveolar volume at which these tests are done.

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Bibliografia
[1.]
J.B. Cadigan, A. Marks, M.F. Ellicott, R.H. Jones, E.A. Gaensler.
An analysis of factors affecting the measurement of pulmonary diffusing capacity by the single breath method.
J Clin Invest, 40 (1961), pp. 1495
[2.]
G.H. Gurtner, W.S. Fowler.
Interrelationships of factors affecting pulmonary diffusing capacity.
J Appl Physiol, 30 (1971), pp. 619
[3.]
J.M. Miller, R.L. Johnson.
Effect of lung inflation on pulmonary diffusing capacity at rest and exercise.
J Clin Invest, 45 (1966), pp. 493
[4.]
N.A.J. Hamer.
Variations in the components of the diffusing capacity as the lung expands.
Clin Sci, 24 (1963), pp. 275
[5.]
D.J. Lipscomb, K. Patel, J.M.B. Hughes.
Interpretetion of increases in the transfer coefficient for carbon monoxide (TLco/Va or Kco).
Thorax, 33 (1978), pp. 728
[6.]
C.M. Ogilvie, R.E. Forster, W.S. Blakemore, J.W. Morton.
A standardized breath holding technique for the clinical measurement of the diffusing capacity of the lung for carbon monoxide.
J Clin Invest, 36 (1957), pp. 1
[7.]
R.L. Johnson, W.S. Spiecer, J.M. Bishop, R.E. Forster.
Pulmonary capillary blodd volume, flow and diffusing capacity during exercise.
J Appl Physiol, 15 (1960), pp. 893
[8.]
E.M. Mostyn, S. Helle, J.B.L. Gee, L.G. Bentivoglio, D.V. Bates.
Pulmonary diffusing capacity of athletes.
J Appl Physiol, 18 (1963), pp. 687
Copyright © 1982. Sociedad Española de Neumología y Cirugía Torácica
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