Journal Information
Vol. 29. Issue 1.
Pages 3-6 (January - February 1993)
Share
Share
Download PDF
More article options
Vol. 29. Issue 1.
Pages 3-6 (January - February 1993)
Full text access
Factores pronósticos y supervivencia en el tratamiento quirúrgico del carcinoma broncopulmonar no anaplásico de células pequeñas en estadio I
Prognostic factors and survival in the surgical treatment of non anaplastic small cell stage I lung cancer
Visits
3409
J. Padilla Alarcón, E. Blasco Armengod, J.M. Borro Maté, G. Galán Gil, F. París Romeu
Servicio de Cirugía Torácica. Hospital Universitario La Fe. Valencia
This item has received
Article information
Abstract
Bibliography
Download PDF
Statistics

Se presenta una serie de 461 pacientes operados de carcino ma broncopulmonar no anaplásico de células pequeñas y clasi ficados en estadio I según la normativa propuesta por la SEPAR. La mortalidad postoperatoria fue de 3,9% y la supervivencia a los cinco años de 61±2,5%. Se analizaron una serie de factores pronósticos, siendo la presencia o ausen cia de síntomas (p=0,0023), el tiempo de enfermedad (p=0,0130), la estirpe histológica (p=0,0497) sobre todo escamoso versus no escamoso (p=0,0110), el tamaño tumoral (p=0,0439) y el grado de invasión tumoral (p=0,0110) los que influyeron significativamente en la supervivencia de los pacientes.

A series of 461 patients operated on for non anaplastic small cell bronchopulmonary carcinoma classified as stage I according to the norms proposed by SEPAR is presented. Postoperative mortality was 3.9% and survival at 5 years was 61±2.5%. A series of prognostic factors were analyzed with the presence or absence of symptoms (p=0.0023), the length of time of the disease (p=0.0130), histologic strain (p=0.0497) particularly squamous versus non squamous (p=0.0110), tumoral size (p=0.0439) and the degree of tumoral invasion (p=0.0110) being those which most significantly influenced the survival of these patients.

Full text is only aviable in PDF
Bibliografía
[1.]
A. López Encuentra, C. León González, J. López Mejías, et al.
Normativa sobre nomenclatura y clasificación del carcinoma broncogénico.
Arch Bronconeumol, 26 (1990), pp. 54-60
[2.]
C.F. Mountain.
A new international staging system for lung cancer.
Chest, 89 (1986), pp. 225s-233s
[3.]
T.W. Shields, E.W. Humphrey, M.Y. Matthews, C.E. Eastridge, R.J. Keenh.
Pathological stage grouping of patients with resected carcinoma of the lung.
J Thorac Cardiovasc Surg, 80 (1980), pp. 400-405
[4.]
N. Martini, E.J. Beattie.
Results of surgical treatment in state I lung cancer.
J Thorac Cardiovasc Surg, 74 (1977),
[5.]
N. Martini.
Preoperative staging and surgery for non small cell lung cancer.
Lung cancer. Contemporary issues in clinical oncology, pp. 101-130
[6.]
C.F. Mountain, M.H. Gail.
Surgical adjuvant intrapleural BCG treatment for stage I non-small cell lung cancer: Preliminary report of the National Cancer Institute Lung Cancer Study Group.
J Thorac Cardiovasc Surg, 82 (1981), pp. 649-657
[7.]
Fry WA. En la discusión de Litte AG (cf. 21).
[8.]
D.W. Moores, M.F. McKneally.
Tratamiento del cáncer pulmonar en etapa I (T1N0M0 T2N0M0).
Surg Clin North Am, 67 (1987), pp. 965-971
[9.]
P.C. Pairolero, D.E. Williams, E.J. Bergstralh, J.M. PiehIer, P.E. Bernatz, W.S. Payne.
Postsurgical stage I bronchogenic carcinoma: morbid implications of recurrent disease.
Ann Thorac Surg, 38 (1984), pp. 331-338
[10.]
T. Naruke, T. Goya, R. Tsuchiya, K. Suemasu.
Prognosis and survival in resected lung carcinoma based on the new international staging system.
J Thorac Cardiovasc Surg, 96 (1988), pp. 440-447
[11.]
E.H. Lipford, J.C. Eggleston, K.D. Lillemoe, D.L. Sears, G.W. Moore, R.R. Baker.
Prognostic factors in surgically resected limited-stage non-small cell carcinoma of the lung.
Am J Surg Pathol, 8 (1984), pp. 357-365
[12.]
N. Roeslin, G. Chaikiadakis, P. Dumoint, J.P. Witz.
A better prognostic value from a modification of lung cancer staging.
J Thorac Cardiovasc Surg, 94 (1987), pp. 504-509
[13.]
R.C. Read, R. Schaefer, N. North, R. Walls.
Diameter, cell type and survival in stage I primary non-small cell lung cancer.
Arch Surg, 123 (1988), pp. 446-449
[14.]
E.L. Kaplan, P. Meier.
Non parametric estimation from incomplete observations.
J Am Stat Assoc, 53 (1958), pp. 457-481
[15.]
N. Breslow.
A generalized Kruskal-Wallis test for comparing K samples subject to unequal patterns of censorship.
Biometrika, 57 (1970), pp. 579-594
[16.]
N. Mantel.
Evaluation of survival data and two new rank order statistic arising in its consideration.
Cancer Chemother Rep, 50 (1966), pp. 163-170
[17.]
R. Tarone, J. Ware.
On distribution free test for equality of survival distribution.
Biometrika, 64 (1977), pp. 156-160
[18.]
D.R. Cox.
Regression model and life tables.
J R Stat Soc, 34 (1972), pp. 187-220
[19.]
W.J. Dixon.
BMDP statistical software.
University California Press, (1983),
[20.]
R.J. Ginsber, L.D. Hill, R.T. Eagan, et al.
Modern 30 day operative mortality for surgical resection in lung cancer.
J Thorac Cardiovasc Surg, 86 (1983), pp. 654-658
[21.]
A.G. Litte, T.R. DeMeester, M.K. Ferguson, et al.
Modified stage I (T1N0M0 T2N0M0), non-small cell lung cancer: Treatment results, recurrence patterns and adjuvant immunotherapy.
Surgery, 100 (1986), pp. 621-628
[22.]
M.H. Gail, R.T. Eagan, R. Feld, The Lung Cancer Study Group, et al.
Prognostic factors in patients with resected state I non-small cell lung cancer.
Cancer, 54 (1984), pp. 1.802-1.813
[23.]
R. Feld, L.V. Rubinstein, T. Weisenburguer, The Lung Cancer Study Group.
Sites of recurrence in resected stage I non-small-cell lung cancer: A guide for future studies.
J Clin Oncol, 2 (1984), pp. 1.352-1.357
[24.]
P.I. Tartter, L. Burrows, P. Kirschner.
Perioperative blood transfusion adversely affects prognosis after resection of stage I (subset N0) non-oat cell lung cancer.
J Thorac Cardiovasc Surg, 88 (1984), pp. 659-662
Copyright © 1993. Sociedad Española de Neumología y Cirugía Torácica
Archivos de Bronconeumología
Article options
Tools

Are you a health professional able to prescribe or dispense drugs?