array:22 [
  "pii" => "S0300289615325643"
  "issn" => "03002896"
  "doi" => "10.1016/S0300-2896(15)32564-3"
  "estado" => "S300"
  "fechaPublicacion" => "1979-04-01"
  "aid" => "72633"
  "copyright" => "Sociedad Española de Neumología y Cirugía Torácica"
  "copyrightAnyo" => "1979"
  "documento" => "article"
  "crossmark" => 0
  "subdocumento" => "fla"
  "cita" => "Arch Bronconeumol. 1979;15:51-4"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:2 [
    "total" => 1112
    "formatos" => array:3 [
      "EPUB" => 60
      "HTML" => 554
      "PDF" => 498
    ]
  ]
  "itemSiguiente" => array:18 [
    "pii" => "S0300289615325655"
    "issn" => "03002896"
    "doi" => "10.1016/S0300-2896(15)32565-5"
    "estado" => "S300"
    "fechaPublicacion" => "1979-04-01"
    "aid" => "72634"
    "copyright" => "Sociedad Española de Neumología y Cirugía Torácica"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Arch Bronconeumol. 1979;15:55-9"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:2 [
      "total" => 1248
      "formatos" => array:3 [
        "EPUB" => 41
        "HTML" => 486
        "PDF" => 721
      ]
    ]
    "es" => array:10 [
      "idiomaDefecto" => true
      "titulo" => "Tumores de esternon. Reparacion parietal postesternectomia"
      "tienePdf" => "es"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "es"
        1 => "en"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "55"
          "paginaFinal" => "59"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "en" => array:1 [
          "titulo" => "Tumors of the sternum. Poststernonectomy parietal reparation"
        ]
      ]
      "contieneResumen" => array:2 [
        "es" => true
        "en" => true
      ]
      "contienePdf" => array:1 [
        "es" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "R. Vara Thorbeck, J.M. Maza Inza, O.I. Morales Valentín, J. Sánchez Fernández-Bravo"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "R."
              "apellidos" => "Vara Thorbeck"
            ]
            1 => array:2 [
              "nombre" => "J.M."
              "apellidos" => "Maza Inza"
            ]
            2 => array:2 [
              "nombre" => "O.I."
              "apellidos" => "Morales Valentín"
            ]
            3 => array:2 [
              "nombre" => "J."
              "apellidos" => "Sánchez Fernández-Bravo"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "es"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615325655?idApp=UINPBA00003Z"
    "url" => "/03002896/0000001500000002/v1_201509151322/S0300289615325655/v1_201509151322/es/main.assets"
  ]
  "es" => array:12 [
    "idiomaDefecto" => true
    "titulo" => "Estudio de la medula osea mediante biopsia-aspiracion de cresta iliaca en 46 enfermos con carcinoma broncopulmonar primitivo. Su correlacion con el estudio radiologico oseo y radioisotopico con 99m Tc"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "51"
        "paginaFinal" => "54"
      ]
    ]
    "autores" => array:1 [
      0 => array:3 [
        "autoresLista" => "P. Gómez Fernández, R. Rey Durán, R. Salama Benoliel, J. Martín Villar, M. Zomeño Gómez, J.M. Fernández Rocha"
        "autores" => array:6 [
          0 => array:2 [
            "nombre" => "P."
            "apellidos" => "Gómez Fernández"
          ]
          1 => array:2 [
            "nombre" => "R."
            "apellidos" => "Rey Durán"
          ]
          2 => array:2 [
            "nombre" => "R."
            "apellidos" => "Salama Benoliel"
          ]
          3 => array:2 [
            "nombre" => "J."
            "apellidos" => "Martín Villar"
          ]
          4 => array:2 [
            "nombre" => "M."
            "apellidos" => "Zomeño Gómez"
          ]
          5 => array:2 [
            "nombre" => "J.M."
            "apellidos" => "Fernández Rocha"
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:2 [
            "entidad" => "Servicio de Bronconeumotogía. Hospital de Enfermedades del Tórax Victoria Eugenia. Madrid."
            "identificador" => "aff0005"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "en" => array:1 [
        "titulo" => "Study of the osseous medulla by means of biopsy-aspiration of the iliac crest in 46 patients suffering from primitive bronchopulmonary carcinoma. Correlation with the osseous radiological study and with the radioisotopic study using 99 mtc"
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "1978-07-07"
    "tieneResumen" => true
    "resumen" => array:2 [
      "es" => array:2 [
        "titulo" => "Resumen"
        "resumen" => "<span id="absec0005" class="elsevierStyleSection elsevierViewall"><p id="sp0005" class="elsevierStyleSimplePara elsevierViewall">Se realiz&#243; biopsia-aspiraci&#243;n de m&#233;dula &#243;sea&#44; gammagraf&#237;a con 99 mTc y serie radiol&#243;gica &#243;sea en 46 enfermos con carcinoma broncopulmonar primitivo&#59; se establecieron correlaciones entre los tres m&#233;todos&#46;</p><p id="sp0010" class="elsevierStyleSimplePara elsevierViewall">De los resultados obtenidos se deduce que el m&#233;todo m&#225;s sensible para detectar invasi&#243;n &#243;sea en el carcinoma broncopulmonar es la gammagraf&#237;a&#44; con la que hallamos -32&#44;6 &#37; de met&#225;stasis frente a 19&#44;5 &#37; y 17&#44;3 &#37; evidenciadas por la radiolog&#237;a y biopsia-aspiraci&#243;n de m&#233;dula&#44; respectivamente&#59; por otra parte&#44; el porcentaje de falsos negativos es menor en la gammagraf&#237;a &#40;17&#44;3 &#37;&#41; que en la radiolog&#237;a &#40;34&#44;7 &#37;&#41; y biopsia-aspiraci&#243;n &#40;41&#44;3&#37;&#41;&#46;</p><p id="sp0015" class="elsevierStyleSimplePara elsevierViewall">Tambi&#233;n se demuestra la gran utilidad de la biopsia-aspiraci&#243;n de la m&#233;dula &#243;sea para establecer la presencia de afectaci&#243;n &#243;sea en el carcinoma indiferenciado de c&#233;lulas peque&#241;as y que en nuestra serie alcanza un 40 &#37;&#46;</p></span>"
      ]
      "en" => array:2 [
        "titulo" => "Summary"
        "resumen" => "<span id="absec0010" class="elsevierStyleSection elsevierViewall"><p id="sp0020" class="elsevierStyleSimplePara elsevierViewall">The author scarried out biopsy-aspiration of osseous medulla gammagraphy with 99 mTc&#44; and a osseous radiological series in 46 patients suffering from primitive&#59; bronchopulmonary carcinoma&#44; and also established the correlation between the three methods&#46;</p><p id="sp0025" class="elsevierStyleSimplePara elsevierViewall">From the results obtained&#44; the authors deduce that the most sensitive method for detecting osseous invasion in bronchopulmonary carcinoma gammagraphy&#44; with which 32&#46;6 &#37; metastasis was found as compared 19&#46;5 &#37; and 17&#46;3 &#37; shown by the radiology and biopsy-aspiration medulla&#44; respectively&#46; On the other hand&#44; the percentage of false negative is lower in gammagraphy &#40;17&#46;3 &#37;&#41; that in radiology &#40;34&#46;7 &#37;&#41; and biopsy-aspiration &#40;41&#46;3 &#37;&#41;&#46;</p><p id="sp0030" class="elsevierStyleSimplePara elsevierViewall">The authors also demonstrate the great utility of biopsyaspiration of the osseous medulla for establishing the presence of osseous affection undifferentiated carcinoma of small cells&#44; that reached 40 &#37; in the author series&#46;</p></span>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "Bibliografia"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:10 [
            0 => array:3 [
              "identificador" => "bib0005"
              "etiqueta" => "1&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Eariy detection of bone marrow invasi&#243;n in Oat cell carcinoma of the lung"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "H&#46; Hansen"
                            1 => "F&#46; Muggia"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1056/NEJM197104292841708"
                      "Revista" => array:5 [
                        "tituloSerie" => "New Engl&#46; J&#46; Med&#46;"
                        "fecha" => "1971"
                        "volumen" => "284"
                        "paginaInicial" => "962"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5551805"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0010"
              "etiqueta" => "2&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "WATSON&#44; W&#46;L&#46;&#58; Lung c&#225;ncer&#44; p&#225;g&#46; 507&#46; St&#46; Louis&#44; 1968&#46; in press&#46;"
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0015"
              "etiqueta" => "3&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Bone marrow examination in 100&#46; consecutive patients with bronchogenic carcinoma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "H&#46; Hansen"
                            1 => "F&#46; Muggia"
                            2 => "O&#46; Se-Lawwry"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Lancet"
                        "fecha" => "1971"
                        "volumen" => "2"
                        "paginaInicial" => "443"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11905739"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0020"
              "etiqueta" => "4&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Diagnosis of metastatic carcinoma by bone marrow biopsy versus bone marrow aspiration"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "I&#46; Roeckel"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "Ann&#46; di&#46; Lab&#46; Sci&#46;"
                        "fecha" => "1974"
                        "volumen" => "4"
                        "paginaInicial" => "193"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0025"
              "etiqueta" => "5&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Biopsia de m&#233;dula &#243;sea en linfomas&#44; carcinomas y enfermedades granulomatosas"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "L&#46; Ellman"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "Am&#46; J&#46; Med&#46; &#40;ed&#46; esp&#46;&#41;"
                        "fecha" => "1976"
                        "volumen" => "3"
                        "paginaInicial" => "25"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0030"
              "etiqueta" => "6&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Limitations of bone scanning in clinical oncology"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "K&#46; Loeffler"
                            1 => "R&#46; Disimone"
                            2 => "W&#46; Howland"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "JAMA"
                        "fecha" => "1975"
                        "volumen" => "234"
                        "paginaInicial" => "1228"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1242747"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S1473309913700069"
                          "estado" => "S300"
                          "issn" => "14733099"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "7&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Bo marrow biopsy with unaltered architecture&#58; new biopsy device"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "K&#46; Jamishidi"
                            1 => "W&#46; Swaim"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "J&#46; Lab&#46; Cli&#46; Med&#46;"
                        "fecha" => "1971"
                        "volumen" => "77"
                        "paginaInicial" => "3"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0040"
              "etiqueta" => "8&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Lu c&#225;ncer&#58; To op&#233;rate or not&#63;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "C&#46; Mittan"
                            1 => "I&#46; Bruderman"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Am&#46; Rev&#46; Res&#46; Di"
                        "fecha" => "1977"
                        "volumen" => "116"
                        "paginaInicial" => "477"
                        "itemHostRev" => array:3 [
                          "pii" => "S0264410X09006173"
                          "estado" => "S300"
                          "issn" => "0264410X"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib0045"
              "etiqueta" => "9&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Screening for bone met&#225;stasis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "D&#46; Pistemna"
                            1 => "M&#46;C&#46; Dougall"
                            2 => "J&#46; Kriss"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "JAM"
                        "fecha" => "1971"
                        "volumen" => "231"
                        "paginaInicial" => "46"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib0050"
              "etiqueta" => "10&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Bone scanning in ossec metastatic disease"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "R&#46;E&#46; O&#8217;mara"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "JAMA"
                        "fecha" => "1974"
                        "volumen" => "229"
                        "paginaInicial" => "1915"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4479068"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "es"
  "url" => "/03002896/0000001500000002/v1_201509151322/S0300289615325643/v1_201509151322/es/main.assets"
  "Apartado" => array:4 [
    "identificador" => "9277"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Originales"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/03002896/0000001500000002/v1_201509151322/S0300289615325643/v1_201509151322/es/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289615325643?idApp=UINPBA00003Z"
]
Share
Journal Information
Vol. 15. Issue 2.
Pages 51-54 (April - June 1979)
Share
Share
Download PDF
More article options
Vol. 15. Issue 2.
Pages 51-54 (April - June 1979)
Full text access
Estudio de la medula osea mediante biopsia-aspiracion de cresta iliaca en 46 enfermos con carcinoma broncopulmonar primitivo. Su correlacion con el estudio radiologico oseo y radioisotopico con 99m Tc
Study of the osseous medulla by means of biopsy-aspiration of the iliac crest in 46 patients suffering from primitive bronchopulmonary carcinoma. Correlation with the osseous radiological study and with the radioisotopic study using 99 mtc
Visits
4067
P. Gómez Fernández, R. Rey Durán, R. Salama Benoliel, J. Martín Villar, M. Zomeño Gómez, J.M. Fernández Rocha
Servicio de Bronconeumotogía. Hospital de Enfermedades del Tórax Victoria Eugenia. Madrid.
This item has received
Article information
Resumen

Se realizó biopsia-aspiración de médula ósea, gammagrafía con 99 mTc y serie radiológica ósea en 46 enfermos con carcinoma broncopulmonar primitivo; se establecieron correlaciones entre los tres métodos.

De los resultados obtenidos se deduce que el método más sensible para detectar invasión ósea en el carcinoma broncopulmonar es la gammagrafía, con la que hallamos -32,6 % de metástasis frente a 19,5 % y 17,3 % evidenciadas por la radiología y biopsia-aspiración de médula, respectivamente; por otra parte, el porcentaje de falsos negativos es menor en la gammagrafía (17,3 %) que en la radiología (34,7 %) y biopsia-aspiración (41,3%).

También se demuestra la gran utilidad de la biopsia-aspiración de la médula ósea para establecer la presencia de afectación ósea en el carcinoma indiferenciado de células pequeñas y que en nuestra serie alcanza un 40 %.

Summary

The author scarried out biopsy-aspiration of osseous medulla gammagraphy with 99 mTc, and a osseous radiological series in 46 patients suffering from primitive; bronchopulmonary carcinoma, and also established the correlation between the three methods.

From the results obtained, the authors deduce that the most sensitive method for detecting osseous invasion in bronchopulmonary carcinoma gammagraphy, with which 32.6 % metastasis was found as compared 19.5 % and 17.3 % shown by the radiology and biopsy-aspiration medulla, respectively. On the other hand, the percentage of false negative is lower in gammagraphy (17.3 %) that in radiology (34.7 %) and biopsy-aspiration (41.3 %).

The authors also demonstrate the great utility of biopsyaspiration of the osseous medulla for establishing the presence of osseous affection undifferentiated carcinoma of small cells, that reached 40 % in the author series.

Full text is only aviable in PDF
Bibliografia
[1.]
H. Hansen, F. Muggia.
Eariy detection of bone marrow invasión in Oat cell carcinoma of the lung.
New Engl. J. Med., 284 (1971), pp. 962
[2.]
WATSON, W.L.: Lung cáncer, pág. 507. St. Louis, 1968. in press.
[3.]
H. Hansen, F. Muggia, O. Se-Lawwry.
Bone marrow examination in 100. consecutive patients with bronchogenic carcinoma.
Lancet, 2 (1971), pp. 443
[4.]
I. Roeckel.
Diagnosis of metastatic carcinoma by bone marrow biopsy versus bone marrow aspiration.
Ann. di. Lab. Sci., 4 (1974), pp. 193
[5.]
L. Ellman.
Biopsia de médula ósea en linfomas, carcinomas y enfermedades granulomatosas.
Am. J. Med. (ed. esp.), 3 (1976), pp. 25
[6.]
K. Loeffler, R. Disimone, W. Howland.
Limitations of bone scanning in clinical oncology.
JAMA, 234 (1975), pp. 1228
[7.]
K. Jamishidi, W. Swaim.
Bo marrow biopsy with unaltered architecture: new biopsy device.
J. Lab. Cli. Med., 77 (1971), pp. 3
[8.]
C. Mittan, I. Bruderman.
Lu cáncer: To opérate or not?.
Am. Rev. Res. Di, 116 (1977), pp. 477
[9.]
D. Pistemna, M.C. Dougall, J. Kriss.
Screening for bone metástasis.
JAM, 231 (1971), pp. 46
[10.]
R.E. O’mara.
Bone scanning in ossec metastatic disease.
JAMA, 229 (1974), pp. 1915
Copyright © 1979. Sociedad Española de Neumología y Cirugía Torácica
Archivos de Bronconeumología
Article options
Tools

Are you a health professional able to prescribe or dispense drugs?