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Vol. 25. Issue 8.
Pages 318-321 (November - December 1989)
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Vol. 25. Issue 8.
Pages 318-321 (November - December 1989)
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Estudio del patrón ventilatorio y del impulso inspiratorio central en la obesidad extrema
Study of the ventilatory pattern and the central inspiratory drive in extreme obesity
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P. Val, J.A. Carretero, J.A. Domingo, C. Sánchez, J.A. Pasamar
Hospital General Royo Villanova
J.M. Domingo*
* Facultad de Medicina. Zaragoza
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La obesidad es una enfermedad endocrino-metabólica que se asocia con numerosas complicaciones tanto a nivel somático como psíquico. Presentamos una serie de siete pacientes con obesidad extrema, sin patología respiratoria y normocápnicos. Se estudia y comenta su función respiratoria, haciendo especial hincapié en el patrón ventilatorio. De los resultados destacamos la existencia de un impulso inspiratorio central elevado con normalidad del resto de parámetros del patrón ventilatorio, probablemente debido a la buena función de la musculatura inspiratoria de nuestras pacientes.

Obesity is an endocrine and metabolic abnormality which is associated with several both somatic and psychological complications. We report a series of seven patients with extreme obesity, without respiratory disease and with normocapnia. Their respiratory function is discussed with special emphasis on the ventilatory pattern. As a remarkable finding there was an increased central inspiratory drive with normality of the other ventilatory pattern parameters, probably owing to the good performance of the respiratory muscles in our patients.

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Bibliografía
[1.]
R. Carmena, J. Martínez Valls.
Obesidad: Patogenia y tratamiento Medicine.
4.a, IDEPSA, (1985), pp. 1.628-1.642
[2.]
W.H. Cleland, C.R. Mendelson, E.R. Simpson.
Effects of aging and obesity on aromatase activity of human adipose cells.
J Clin Endocrinol Metab., 60 (1985), pp. 174-177
[3.]
W.H. Cleland, et al.
Jour Clin Endoc Metab, 60 (1985), pp. 174-177
[4.]
T.B. Van Itallie.
The problem of obesity: Health implications of overweight and obesity in the Unitet States.
Ann Intern Med, 103 (1985), pp. 983-988
[5.]
C.M. Ogilvie, R.E. Forster, N.S. Blakemore, J.W. Morton.
A standardized breathholding technique for the clinical measurement of the diffusing capacity of the lung for carbon monoxide.
J Clin Invest, 36 (1957), pp. 1-17
[6.]
Standardized lung function testing.
Report of Working Party “Standardization of lung function tests”. Ph H Quanjer (Ed) Eur Com Coal and Steel, Luxembourg, July 1983.
Bull Eur Physiopath Resp, 19 (1983), pp. 22-27
[7.]
Normativa sobre gasometría arterial.
Recomendaciones SEPAR Sociedad Española de Patología del Aparato Respiratorio.
Ed. Doyma, (1987),
[8.]
J. Sorli, A. Grassino, G. Lorange, J. Milic-Emili.
Control of breathing in patients with chronic obstructive pulmonary disease.
Clin Sci Mol Med, 54 (1978), pp. 295-304
[9.]
W.A. Whitelaw, J.P.H. Derenne, J. Milic-Emili.
Occlusion pressure as a measure of respiratory center output in conscious man.
Res Physiol, 23 (1975), pp. 181-195
[10.]
A. Miller.
Patterns of impairment.
Pulmonary function tests: A guide for the student and house officer, pp. 151-161
[11.]
C.S. Ray, D.Y. Sue, G. Bray, et al.
Effects of obesity on respiratory function.
Am Rev Respir Dis, 128 (1983), pp. 501-506
[12.]
S.I. Said.
Abnormalities of pulmonary gas exchange in obesity.
Ann Intern Med, 53 (1960), pp. 1.121-1.129
[13.]
Marín Trigo JM, Pasamar JA, Candel M, Duplá A. Artificial obesity and respiratory drive. 18th Annual Meeting of SEPCR. Barcelona 1984.
[14.]
A. Naimark, R.M. Cherniak.
Compliance of the respiratory System and its components in health and obesity.
J Appl Physiol, 15 (1960), pp. 377-382
[15.]
J.T. Sharp, M. Barrocas, S. Chokroverty.
The cardiorespiratory effects of obesity.
Clin Chest Med, 1 (1980), pp. 103-108
[16.]
D.F. Rochester, Y. Enson.
Current concepts in the pathogenesis of the obesity-hypoventilation syndrome.
Am J Med, 57 (1974), pp. 402-420
[17.]
M.R. Partridge, G. Ciofetta, J.M.B. Hughes.
Topography of ventilation-perfusion ratios in obesity.
Bull Eur Physiopath Resp, 14 (1978), pp. 765-773
[18.]
H.S. Holley, J. Milic-Emili, M.R. Becklake, D.V. Bates.
Regional distribution of pulmonary ventilation and perfusion in obesity.
J Clin Invest, 46 (1967), pp. 475-482
[19.]
F. Barrera, P. Hillyer, G. Ascanio, J. Bechtel.
The distribution of ventilation, difussion and blood flow in obese patients with normal and abnormal blood gases.
Am Rev Respir Dis, 108 (1973), pp. 819-830
[20.]
G.N. Bedell, W.R. Wilson, P.M. Seebohm.
Pulmonary function in obese persons.
J Clin Invest, 337 (1958), pp. 1.019-1.060
[21.]
J. Canet, J. Viñas, D. Navajas, et al.
Variabilidad del patrón respiratorio en reposo.
Arch Bronconeumol, 20 (1984), pp. 20
[22.]
M. Aubier.
L’exploration de la régulation de la ventilation.
R P, 35 (1985), pp. 983-992
[23.]
J. Milic-Emili, M.M. Grunstein.
Drive and timing components of ventilation.
Chest, 70 (1976), pp. 131-133
[24.]
G.J. Gibson.
Metabolic and endocrine disorders.
Clinical tests of respiratory function, pp. 291-298
[25.]
G.A. Bray.
Complications of obesity.
Ann Intem Med, 103 (1985), pp. 1.052-1.062
[26.]
Marín Trigo JM. Aportación de la presión de oclusión e impedancia inspiratoria efectiva en el estudio del control de la ventilación en la EPOC. Tesis Doctoral Zaragoza 1985.
[27.]
J.M. Marín, M. Candel, J.A. Pasamar, A. Sebastián, A. Duplá.
Patrón de la respiración durante la compresión abdominal en sujetos sanos y obstructivos crónicos.
Arch Bronconeumol, 21 (1985), pp. 44-45
[28.]
M. Lopata, E. Onal.
Mass loading, sleep apnoea and the pathogenesis of obesity hypoventilation.
Am Rev Respir Dis, 126 (1982), pp. 640-645
[29.]
R.V. Lourenço.
Diaphragm activity in obesity.
J Clin Invest., 48 (1969), pp. 1.609-1.614
Copyright © 1989. Sociedad Española de Neumología y Cirugía Torácica
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