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Groundglass opacification and nodular consolidation right middle lobe&#46; The clinical history of recurrent chest infections and a combination of imaging findings were consistent with Mounier-Kuhn Syndrome &#40;MKS&#41;&#46; The patient was treated with antibiotic and educated to improve airway clearance techniques&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">The MKS is a rare disorder characterized by the enlarged trachea and main bronchi&#46; It was first described by Pierre-Louis Mounier-Kuhn in 1937 associated with recurrent chest infections<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">1</span></a> and anatomically described as tracheobronchomegaly &#40;TBM&#41; in 1962&#46;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">1</span></a> The diagnosis can be made on CT by measuring the diameter of the airway&#46; Woodring et al&#46; suggested the following diagnostic criteria for tracheomegaly in adults based on chest radiography tracheal transverse diameter<span class="elsevierStyleHsp" style=""></span>&#62;<span class="elsevierStyleHsp" style=""></span>25<span class="elsevierStyleHsp" style=""></span>mm and sagittal diameter<span class="elsevierStyleHsp" style=""></span>&#62;<span class="elsevierStyleHsp" style=""></span>27<span class="elsevierStyleHsp" style=""></span>mm in males and&#44; 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respectively&#44; fulfilling the diagnostic criteria&#46; This disease is thought to occur from atrophy of the elastic fibers of the trachea and bronchi&#44; leading to thinning of the smooth muscle&#44; and ultimately causing the trachea to become flaccid&#44; dilated and develop tracheobronchomalacia&#46;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">1</span></a> In mild cases&#44; patients are asymptomatic or present only with chronic cough&#46; In rare&#44; severe cases&#44; patients may suffer from pulmonary obstructive diseases such as bronchiectasis&#46;<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">2</span></a> Treatment is mainly supportive&#46; Chest physiotherapy can be proposed to improve mucociliary clearance and antibiotics are administered for the treatment of pulmonary infections&#46; Some patients may benefit from noninvasive positive-pressure ventilation&#44; airway stenting&#44; and surgical tracheoplasty&#46;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">1</span></a></p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Funding</span><p id="par0015" class="elsevierStylePara elsevierViewall">None&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Conflict of interest</span><p id="par0020" class="elsevierStylePara elsevierViewall">None declared&#46;</p></span></span>"
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Clinical Image
Mounier-Kuhn Syndrome: A Rare Cause of Recurrent Chest Infection
Síndrome de Mounier-Kuhn: una causa rara de infección torácica recurrente
Narat Srivalia,b,
Corresponding author
nsrivali@gmail.com

Corresponding author.
, Federica De Giacomia,b
a Division of Pulmonary Medicine (NS), St. Agnes Hospital, Baltimore, MD 21229, USA
b Respiratory Unit (FDG), Cremona Hospital, Cremona, Italy
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Groundglass opacification and nodular consolidation right middle lobe&#46; The clinical history of recurrent chest infections and a combination of imaging findings were consistent with Mounier-Kuhn Syndrome &#40;MKS&#41;&#46; The patient was treated with antibiotic and educated to improve airway clearance techniques&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">The MKS is a rare disorder characterized by the enlarged trachea and main bronchi&#46; It was first described by Pierre-Louis Mounier-Kuhn in 1937 associated with recurrent chest infections<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">1</span></a> and anatomically described as tracheobronchomegaly &#40;TBM&#41; in 1962&#46;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">1</span></a> The diagnosis can be made on CT by measuring the diameter of the airway&#46; Woodring et al&#46; suggested the following diagnostic criteria for tracheomegaly in adults based on chest radiography tracheal transverse diameter<span class="elsevierStyleHsp" style=""></span>&#62;<span class="elsevierStyleHsp" style=""></span>25<span class="elsevierStyleHsp" style=""></span>mm and sagittal diameter<span class="elsevierStyleHsp" style=""></span>&#62;<span class="elsevierStyleHsp" style=""></span>27<span class="elsevierStyleHsp" style=""></span>mm in males and&#44; tracheal transverse diameter<span class="elsevierStyleHsp" style=""></span>&#62;<span class="elsevierStyleHsp" style=""></span>21<span class="elsevierStyleHsp" style=""></span>mm and sagittal diameter<span class="elsevierStyleHsp" style=""></span>&#62;<span class="elsevierStyleHsp" style=""></span>23<span class="elsevierStyleHsp" style=""></span>mm in the female&#46;<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">2</span></a> Different criteria have been suggested diameter of the trachea&#44; right main bronchus&#44; or left main bronchus that exceeds 3&#46;0&#44; 2&#46;4&#44; or 2&#46;3<span class="elsevierStyleHsp" style=""></span>cm&#44; respectively on a standard chest radiograph or bronchogram&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">3</span></a> The diameters in our case were 3&#46;5<span class="elsevierStyleHsp" style=""></span>cm&#44; 2&#46;5<span class="elsevierStyleHsp" style=""></span>cm&#44; and 2&#46;4<span class="elsevierStyleHsp" style=""></span>cm&#44; respectively&#44; fulfilling the diagnostic criteria&#46; This disease is thought to occur from atrophy of the elastic fibers of the trachea and bronchi&#44; leading to thinning of the smooth muscle&#44; and ultimately causing the trachea to become flaccid&#44; dilated and develop tracheobronchomalacia&#46;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">1</span></a> In mild cases&#44; patients are asymptomatic or present only with chronic cough&#46; In rare&#44; severe cases&#44; patients may suffer from pulmonary obstructive diseases such as bronchiectasis&#46;<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">2</span></a> Treatment is mainly supportive&#46; Chest physiotherapy can be proposed to improve mucociliary clearance and antibiotics are administered for the treatment of pulmonary infections&#46; Some patients may benefit from noninvasive positive-pressure ventilation&#44; airway stenting&#44; and surgical tracheoplasty&#46;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">1</span></a></p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Funding</span><p id="par0015" class="elsevierStylePara elsevierViewall">None&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Conflict of interest</span><p id="par0020" class="elsevierStylePara elsevierViewall">None declared&#46;</p></span></span>"
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ISSN: 15792129
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