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Right Lung Agenesis Associated with Dextrocardia and Pulmonary Hypertension
Agenesia pulmonar derecha asociada a dextrocardia e hipertensión pulmonar
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B) Corte axial tomográfico con ventana de parénquima pulmonar. La flecha indica el bronquio principal derecho rudimentario que acaba en fondo de saco. C) Corte axial tomográfico sin contraste intravenoso en el que se aprecia el desplazamiento de estructuras vasculares hacia el hemitórax derecho, así como ausencia de arteria pulmonar derecha. API: arteria pulmonar izquierda. D) Corte axial oblicuo de cine-RM b-FFE. Se observa dextrocardia, dextro-ápex y la ausencia completa de parénquima pulmonar derecho. VD: ventrículo; VI: ventrículo izquierdo.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Isabel María Ordóñez Dios, Miguel Ángel Rienda Moreno, Javier Lázaro Polo" "autores" => array:3 [ 0 => array:2 [ "nombre" => "Isabel María" "apellidos" => "Ordóñez Dios" ] 1 => array:2 [ "nombre" => "Miguel Ángel" "apellidos" => "Rienda Moreno" ] 2 => array:2 [ "nombre" => "Javier" "apellidos" => "Lázaro Polo" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S1579212920300793" "doi" => "10.1016/j.arbr.2020.04.002" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212920300793?idApp=UINPBA00003Z" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289619302807?idApp=UINPBA00003Z" "url" => "/03002896/0000005600000006/v3_202010110737/S0300289619302807/v3_202010110737/es/main.assets" ] ] "itemSiguiente" => array:19 [ "pii" => "S1579212920300781" "issn" => "15792129" "doi" => "10.1016/j.arbr.2020.04.001" "estado" => "S300" "fechaPublicacion" => "2020-06-01" "aid" => "2183" "copyright" => "SEPAR" "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Arch Bronconeumol. 2020;56:391" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Clinical Image</span>" "titulo" => "Rib Fractures, Pulmonary Hernia and Diaphragmatic Rupture After a Fit of Coughing" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "391" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Fracturas costales, hernia pulmonar y rotura diafragmática tras acceso de tos" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 741 "Ancho" => 1756 "Tamanyo" => 255389 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">(A) Three-D reconstruction of computed tomography showing fractures of the 7th, 8th and 9th costal arches and intercostal diastasis of the 7th space, associated with pulmonary herniation. (B) Five cm diaphragmatic defect repaired with Prolene® and polytetrafluoroethylene sutures. (C) Biological mesh (Permacol®) on costal plane.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "M. Teresa Gómez Hernández, Israel Rodríguez Alvarado, Marcelo F. Jiménez López" "autores" => array:3 [ 0 => array:2 [ "nombre" => "M. Teresa" "apellidos" => "Gómez Hernández" ] 1 => array:2 [ "nombre" => "Israel" "apellidos" => "Rodríguez Alvarado" ] 2 => array:2 [ "nombre" => "Marcelo F." "apellidos" => "Jiménez López" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0300289619302571" "doi" => "10.1016/j.arbres.2019.05.005" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289619302571?idApp=UINPBA00003Z" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212920300781?idApp=UINPBA00003Z" "url" => "/15792129/0000005600000006/v1_202006030729/S1579212920300781/v1_202006030729/en/main.assets" ] "itemAnterior" => array:19 [ "pii" => "S1579212920300896" "issn" => "15792129" "doi" => "10.1016/j.arbr.2020.04.003" "estado" => "S300" "fechaPublicacion" => "2020-06-01" "aid" => "2330" "copyright" => "SEPAR" "documento" => "article" "crossmark" => 1 "subdocumento" => "rev" "cita" => "Arch Bronconeumol. 2020;56:380-9" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Review</span>" "titulo" => "The Importance of Imaging Studies in the Assessment of Response to Immunotherapy in Lung Cancer" "tienePdf" => "en" "tieneTextoCompleto" => "en" "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "380" "paginaFinal" => "389" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Importancia de la imagen en la valoración de la respuesta al tratamiento con inmunoterapia del cáncer de pulmón" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0020" "etiqueta" => "Fig. 4" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr4.jpeg" "Alto" => 1903 "Ancho" => 1500 "Tamanyo" => 240305 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Examples of pneumonitis (lung toxicity). (A) A 64-year-old patient with metastatic lung cancer receiving immunotherapy (nivolumab) in whom the appearance of bilateral peribronchial consolidations (black asterisks) was observed on CT. In this case, we decided to perform a core needle lung biopsy of a dominant consolidation in the left lower lobe, which showed foci of organizing pneumonia and absence of tumor cells; the biopsy was complicated by left pneumothorax (white asterisk). (B) A 68-year-old patient with locally advanced lung cancer receiving adjuvant immunotherapy (nivolumab); the left CT image shows the appearance of a lesion (arrow) with air bronchogram in the left lung. In this case, we decided to administer empirical treatment with systemic corticosteroids. A repeat chest CT at 4 weeks (right) confirmed partial resolution of pulmonary opacity (arrow). The radiological pattern suggested organizing pneumonia. (C) A 76-year-old patient with metastatic lung cancer receiving immunotherapy (pembrolizumab) who presented in the emergency department with dyspnea. Chest CT showed extensive bilateral ground glass attenuation opacities (pattern of non-specific interstitial pneumonitis). The patient improved after discontinuation of immunotherapy and administration of systemic corticoids.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Luis Gorospe, Rubén Eduardo Pacios-Blanco, Pilar Garrido-López" "autores" => array:3 [ 0 => array:2 [ "nombre" => "Luis" "apellidos" => "Gorospe" ] 1 => array:2 [ "nombre" => "Rubén Eduardo" "apellidos" => "Pacios-Blanco" ] 2 => array:2 [ "nombre" => "Pilar" "apellidos" => "Garrido-López" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0300289619305800" "doi" => "10.1016/j.arbres.2019.10.023" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289619305800?idApp=UINPBA00003Z" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212920300896?idApp=UINPBA00003Z" "url" => "/15792129/0000005600000006/v1_202006030729/S1579212920300896/v1_202006030729/en/main.assets" ] "en" => array:14 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Clinical Image</span>" "titulo" => "Right Lung Agenesis Associated with Dextrocardia and Pulmonary Hypertension" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "390" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Isabel María Ordóñez Dios, Miguel Ángel Rienda Moreno, Javier Lázaro Polo" "autores" => array:3 [ 0 => array:4 [ "nombre" => "Isabel María" "apellidos" => "Ordóñez Dios" "email" => array:1 [ 0 => "isabelordonezdios@gmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "Miguel Ángel" "apellidos" => "Rienda Moreno" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "Javier" "apellidos" => "Lázaro Polo" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Neumología, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicio de Radiología, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Agenesia pulmonar derecha asociada a dextrocardia e hipertensión pulmonar" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 536 "Ancho" => 576 "Tamanyo" => 61164 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">(A) Chest X-ray, posteroanterior projection, showing mediastinal and left lung shift toward the right hemithorax caused by absence of the right lung (pulmonary agenesis). (B) Tomographic axial slice showing lung parenchyma view. The arrow indicates the rudimentary right main bronchus terminating in the pleural sac. (C) Tomographic axial slice without intravenous contrast showing the shift of vascular structures toward the right hemithorax, and absence of right pulmonary artery. API: Left pulmonary artery. (D) Cine-MR b-FFE oblique axial slice. Dextrocardia, dextro-apex and complete absence of right lung parenchyma are observed. VD: right ventricle; VI: left ventricle.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">We report the case of a 37-year-old man diagnosed at birth with right pulmonary agenesis with dextrocardia, operated at the age of 8 years for persistent arteriovenous fistula, and a history of recurrent respiratory infections with bronchial hyperreactivity. Imaging tests (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>) revealed right pulmonary agenesis with left pulmonary compensatory hyperinflation, anterior transmediastinal herniation, and dextrocardia.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">Pulmonary agenesis is a rare congenital malformation. Congenital anomalies can occur in 3 types:<ul class="elsevierStyleList" id="lis0005"><li class="elsevierStyleListItem" id="lsti0005"><span class="elsevierStyleLabel">–</span><p id="par0015" class="elsevierStylePara elsevierViewall">Type 1 or agenesis: Complete absence of lung parenchyma and vasculature, and bronchial tree.</p></li><li class="elsevierStyleListItem" id="lsti0010"><span class="elsevierStyleLabel">–</span><p id="par0020" class="elsevierStylePara elsevierViewall">Type 2 or aplasia: Rudimentary bronchi with complete absence of lung parenchyma.</p></li><li class="elsevierStyleListItem" id="lsti0015"><span class="elsevierStyleLabel">–</span><p id="par0025" class="elsevierStylePara elsevierViewall">Type 3 or hypoplasia: Presence of variable amounts of lung parenchyma, bronchial tree, and supporting vasculature.<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">1</span></a></p></li></ul></p><p id="par0030" class="elsevierStylePara elsevierViewall">Its etiology is unknown and appears to be the result of multiple factors, including genetics, vitamin A or folic acid deficiency, and viral infections. Left pulmonary agenesis is the most common (70% of cases), and is associated with a more favorable prognosis, since right agenesis is most often associated with abnormalities, usually cardiovascular and gastrointestinal.<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">2</span></a></p><p id="par0035" class="elsevierStylePara elsevierViewall">X-ray and chest CT are essential for diagnosis, the latter being the key to confirmation.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Ordóñez Dios IM, Rienda Moreno MÁ, Lázaro Polo J. Agenesia pulmonar derecha asociada a dextrocardia e hipertensión pulmonar. Arch Bronconeumol. 2020;56:390.</p>" ] ] "multimedia" => array:1 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 536 "Ancho" => 576 "Tamanyo" => 61164 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">(A) Chest X-ray, posteroanterior projection, showing mediastinal and left lung shift toward the right hemithorax caused by absence of the right lung (pulmonary agenesis). (B) Tomographic axial slice showing lung parenchyma view. The arrow indicates the rudimentary right main bronchus terminating in the pleural sac. (C) Tomographic axial slice without intravenous contrast showing the shift of vascular structures toward the right hemithorax, and absence of right pulmonary artery. API: Left pulmonary artery. (D) Cine-MR b-FFE oblique axial slice. Dextrocardia, dextro-apex and complete absence of right lung parenchyma are observed. VD: right ventricle; VI: left ventricle.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0015" "bibliografiaReferencia" => array:2 [ 0 => array:3 [ "identificador" => "bib0015" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Unilateral pulmonary agenesis: a report of four cases, two diagnosed antenatally and literature review" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "S. Kayemba-Kay's" 1 => "V. Couvrat-Carcauzon" 2 => "V. Goua" 3 => "G. Podevin" 4 => "M. Marteau" 5 => "E. Sapin" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1002/ppul.22920" "Revista" => array:6 [ "tituloSerie" => "Pediatr Pulmonol" "fecha" => "2014" "volumen" => "49" "paginaInicial" => "E96" "paginaFinal" => "E102" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24178867" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0020" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Clinical diagnostic approach to congenital agenesis of right lung with dextrocardia: a case report with review of literature" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "L. Xie" 1 => "J. Zhao" 2 => "J. Shen" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/crj.12282" "Revista" => array:7 [ "tituloSerie" => "Clin Respir J" "fecha" => "2016" "volumen" => "10" "paginaInicial" => "805" "paginaFinal" => "808" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25689299" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S188558571730484X" "estado" => "S300" "issn" => "18855857" ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15792129/0000005600000006/v1_202006030729/S1579212920300793/v1_202006030729/en/main.assets" "Apartado" => array:4 [ "identificador" => "60604" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Clinical Images" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/15792129/0000005600000006/v1_202006030729/S1579212920300793/v1_202006030729/en/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212920300793?idApp=UINPBA00003Z" ]
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