Corresponding author at: Camino Margallo nº 29 Vivienda 4 CP: 38206 San Cristóbal de la Laguna (Santa Cruz de Tenerife), Santa Cruz de Tenerife, Spain.
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"apellidos" => "Figueira Gonçalves" "email" => array:1 [ 0 => "juanmarcofigueira@gmail.com" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Servicio de Neumología y Cirugía Torácica, Hospital Universitario Nuestra Señora de la Candelaria (HUNSC), Santa Cruz de Tenerife, Spain" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author at: Camino Margallo nº 29 Vivienda 4 CP: 38206 San Cristóbal de la Laguna (Santa Cruz de Tenerife), Santa Cruz de Tenerife, Spain." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Patología cardiovascular en el paciente con enfermedad pulmonar obstructiva crónica de las islas Canarias. «El mojo picón de nuestras papas»" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 2166 "Ancho" => 2165 "Tamanyo" => 349979 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0010" "detalle" => "Fig. " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Characterization of patients with chronic obstructive pulmonary disease in the Canary Islands. Diagram adapted from various studies conducted in the archipelago.</p> <p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">COTE: COPD-specific co-morbidity test; HTN: hypertension.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Mojo picon is a typical sauce from the Canary Islands, made from oil, vinegar and red pepper, which gives it its characteristic red color. This spicy sauce, used in the olden days by sailors on the high seas to accompany our famous <span class="elsevierStyleItalic">papas arrugadas</span> - wrinkled potatoes - when there was nothing else to eat, is the product of the meeting of different cultures at a time when our islands were a bridge for trade between the Americas, Europe and Africa. Nowadays, when someone from Canary Islands travels abroad, they are immediately associated with this dish, which could almost be seen as their “calling card”. This cultural sauce pot has had its impact not only on gastronomy, but also on the patients of this autonomous community.</p><p id="par0010" class="elsevierStylePara elsevierViewall">Although the Canarian population is considered to be phenotypically Caucasian, their ethnic origins differ from the rest of Spain. The inhabitants of the archipelago are descendants of a mixture of an aboriginal population from northern Africa and European settlers who arrived in the islands in the 15th century.<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> Factors such as the distance from the continent and the geographical features of the islands themselves led to a tendency towards endogamy over many generations. This, in turn, led to the emergence of rare diseases in specific areas of the region, for example, familial hypertrophic cardiomyopathy<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> or rare allele variants in alpha-1 antitrypsin deficiency.<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> The result of this “genetic selection” is that chronic pathologies such as cardiovascular or respiratory diseases may present in more complex forms in inhabitants of the Canary Islands than in the continental population.<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1,4</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">Chronic obstructive pulmonary disease (COPD), for example, is less prevalent in the Canaries than in the rest of Spain,<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a> although several studies seem to suggest that it is more difficult to manage.<a class="elsevierStyleCrossRefs" href="#bib0030"><span class="elsevierStyleSup">6,7</span></a> Patients in the Canaries have a greater comorbidity burden than other Spanish cohorts with a similar degree of obstruction,<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a> complicating their clinical situation. Despite a lower tobacco consumption, these patients show a high prevalence of cardiovascular comorbidity, even at earlier disease stages; reported rates are higher than those described in Spain in general,<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">7</span></a> in Europe, and in the United States. Of particular interest are a greater presence of hypertension (HT), dyslipidemia, obesity, cardiac arrhythmia, and ischemic heart disease (IHD) (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>).</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0020" class="elsevierStylePara elsevierViewall">Most individuals are prompted to seek medical attention because of dyspnea. This symptom encompasses multiple qualitative and quantitative parameters, and as a result, is manifested in this disease in several different ways. The important role of cardiovascular comorbidities in COPD must also be taken into account. In the Canary Islands, the most symptomatic COPD patients (GOLD 2017 groups B and D) have a 4-fold risk of IHD or heart failure (HF), and a 2-fold risk of cardiac arrhythmia, diabetes mellitus type 2 (DM2), HT and peripheral artery disease.<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">8</span></a> These results differ from observations reported in other populations: Kahnert et al.<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">9</span></a> found that in COPD in the United Kingdom, the most symptomatic patients had a risk of IHD of less than 2-fold, and that the risk of HF, DM2, or HT remained non-significant. These results underline the importance of evaluating cardiovascular disease when monitoring symptoms in Canary Islanders, and highlight the risk of heart disease in subjects with a greater degree of dyspnea and cerebrovascular accident in patients with increased probability of exacerbation.<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">10</span></a></p><p id="par0025" class="elsevierStylePara elsevierViewall">With regard to the risk of hospitalization, results obtained in the Lung Health Study<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">11</span></a> showed that up to 42 % of first hospitalizations in patients with mild COPD were due to cardiovascular causes. This must be seen in the light of the results of the SUMMIT study, which determined that the risk of a cardiovascular event after an exacerbation in COPD patients with cardiovascular comorbidity increased by 4-fold in the 30 days after onset, and was as high as 10-fold in patients requiring admission to hospital.<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">12</span></a> A small population-based study conducted in the Canary Islands evaluating the effectiveness of the administration of 13-valent pneumococcal conjugate polysaccharide vaccination in COPD patients with established cardiovascular disease found that the risk of hospitalization for exacerbation in subjects with cardiovascular comorbidity increased up to 9-fold compared to those who did not present this pathology.<a class="elsevierStyleCrossRef" href="#bib0065"><span class="elsevierStyleSup">13</span></a> Due to the high cardiovascular burden of patients in our islands, these data reinforce the need to establish measures to improve the monitoring of comorbidities and to maximize follow-up in the event of exacerbation.</p><p id="par0030" class="elsevierStylePara elsevierViewall">With regard to the impact of comorbidities on the life expectancy of these patients, a study published by Divo et al.<a class="elsevierStyleCrossRef" href="#bib0070"><span class="elsevierStyleSup">14</span></a> concluded that cardiovascular disease, especially IHD, HF, or cardiac arrhythmia, has a negative impact on the survival of patients with COPD in outpatient follow-up. On the basis of the results of that study, we performed a similar analysis in patients in the Canary Islands, and found that the impact of cardiovascular disease differs from the findings of those authors, yet chronic kidney disease acquired a special relevance in the community of the Canaries. No significant impact was detected for the presence of IHD,<a class="elsevierStyleCrossRef" href="#bib0075"><span class="elsevierStyleSup">15</span></a> but this may be because this disease is closely and efficiently managed in the archipelago.</p><p id="par0035" class="elsevierStylePara elsevierViewall">The factors discussed here should lead us to reflect on the differences between the COPD population in the Canary Islands and the Iberian peninsula or Europe, and to bear in mind the specific particularities of our patients. Just like our wrinkled potatoes with spicy sauce, this COPD population has its own identity marked by the complexity of its patients, in which the cardiovascular comorbidity/systemic involvement (what we have colloquially dubbed “the Canaries phenotype”) plays a significant role, and where the combination of hypertension, dyslipidemia, DM2, smoking and obesity is part of our day-to-day experience. Given these facts, then, we must be aware of the need for targeted measures aimed at the correct management of these patients with the goal of improving their quality of care.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2019-05-25" "fechaAceptado" => "2019-07-11" "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Figueira Gonçalves JM. Patología cardiovascular en el paciente con enfermedad pulmonar obstructiva crónica de las islas Canarias. «El mojo picón de nuestras papas». Arch Bronconeumol. 2020;56:57–58.</p>" ] ] "multimedia" => array:1 [ 0 => array:8 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 2166 "Ancho" => 2165 "Tamanyo" => 349979 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0010" "detalle" => "Fig. " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Characterization of patients with chronic obstructive pulmonary disease in the Canary Islands. Diagram adapted from various studies conducted in the archipelago.</p> <p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">COTE: COPD-specific co-morbidity test; HTN: hypertension.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:15 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "[1]" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Genomic Analyses of Human European Diversity at the Southwestern Edge: Isolation, African Influence and Disease Associations in the Canary Islands" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "B. Guillen-Guio" 1 => "J.M. Lorenzo-Salazar" 2 => "R. González-Montelongo" 3 => "A. Díaz-de Usera" 4 => "I. Marcelino-Rodríguez" 5 => "A. Corrales" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Mol Biol Evol." "fecha" => "2018" "volumen" => "35" "paginaInicial" => "3010" "paginaFinal" => "3026" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "[2]" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Inherited Cardiac Diseases Program of the Spanish Cardiovascular Research Network (Red Investigación Cardiovascular). Genetic basis of familial dilated cardiomyopathy patients undergoing heart transplantation" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "S. Cuenca" 1 => "M.J. Ruiz-Cano" 2 => "J.R. Gimeno-Blanes" 3 => "A. Jurado" 4 => "C. Salas" 5 => "I. Gomez-Diaz" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.healun.2015.12.014" "Revista" => array:6 [ "tituloSerie" => "J Heart Lung Transplant." "fecha" => "2016" "volumen" => "35" "paginaInicial" => "625" "paginaFinal" => "635" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26899768" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "[3]" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Spectrum of Alpha-1 Antitripsin Deficiency Mutations Detected in Tenerife" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "F. Martínez Bugallo" 1 => "J.M. Figueira Gonçalves" 2 => "M.D. Martín Martínez" 3 => "D. Díaz Pérez" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.arbres.2017.03.005" "Revista" => array:7 [ "tituloSerie" => "Arch Bronconeumol." "fecha" => "2017" "volumen" => "53" "paginaInicial" => "595" "paginaFinal" => "596" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/28427797" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0264410X13004659" "estado" => "S300" "issn" => "0264410X" ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "[4]" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Epidemiology of diabetes-related lower extremity amputations in Gran Canaria, Canary Islands (Spain)" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "J. Aragón-Sánchez" 1 => "A. García-Rojas" 2 => "J.L. Lázaro-Martínez" 3 => "Y. Quintana-Marrero" 4 => "M. Maynar-Moliner" 5 => "M. Rabellino" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Diabetes Res Clin Pract." "fecha" => "2009" "volumen" => "86" "paginaInicial" => "e6" "paginaFinal" => "e84" ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "[5]" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Prevalence of chronic obstructive pulmonary disease in the Canary Islands" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "C. Cabrera López" 1 => "G. Juliá Serdá" 2 => "C. Cabrera Lacalzada" 3 => "A. Martín Medina" 4 => "J.A. Gullón Blanco" 5 => "M.Á García Bello" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.arbres.2013.12.006" "Revista" => array:6 [ "tituloSerie" => "Arch Bronconeumol" "fecha" => "2014" "volumen" => "50" "paginaInicial" => "272" "paginaFinal" => "277" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24507558" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0030" "etiqueta" => "[6]" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Comparison of the prognostic capability of two comorbidity indices in patients with chronic obstructive pulmonary disease, in real-life clinical practice" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "J.M. Figueira Gonçalves" 1 => "R. Golpe" 2 => "M.A. García Bello" 3 => "I. García-Talavera" 4 => "O. Castro Añon" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/crj.13025" "Revista" => array:6 [ "tituloSerie" => "Clin Respir J." "fecha" => "2019" "volumen" => "13" "paginaInicial" => "404" "paginaFinal" => "407" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/30950184" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0035" "etiqueta" => "[7]" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cardiovascular comorbidity in patients with chronic obstructive pulmonary disease in the Canary Islands (CCECAN study)" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "J.M. Figueira Gonçalves" 1 => "R. Dorta Sánchez" 2 => "M.D.C. Rodriguez Pérez" 3 => "P. Viña Manrique" 4 => "D. Díaz Pérez" 5 => "C. Guzmán Saenz" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.arteri.2017.01.003" "Revista" => array:6 [ "tituloSerie" => "Clin Investig Arterioscler." "fecha" => "2017" "volumen" => "29" "paginaInicial" => "149" "paginaFinal" => "156" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/28390852" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib0040" "etiqueta" => "[8]" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Health Status in Patients with COPD According to GOLD 2017 Classification: Use of the COMCOLD Score in Routine Clinical Practice" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "J.M. Figueira Gonçalves" 1 => "M.D. Martín Martínez" 2 => "L.I. Pérez Méndez" 3 => "M.A. García Bello" 4 => "I. Garcia-Talavera" 5 => "S.G. Hernández" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.15326/jcopdf.6.1.2018.0164" "Revista" => array:7 [ "tituloSerie" => "COPD" "fecha" => "2018" "volumen" => "6" "paginaInicial" => "1" "paginaFinal" => "8" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/30775419" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0264410X1400187X" "estado" => "S300" "issn" => "0264410X" ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib0045" "etiqueta" => "[9]" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The revised GOLD 2017 COPD categorization in relation to comorbidities" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "K. Kahnert" 1 => "P. Alter" 2 => "D. Young" 3 => "T. Lucke" 4 => "J. Heinrich" 5 => "R.M. Huber" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.rmed.2017.12.003" "Revista" => array:7 [ "tituloSerie" => "Respir Med" "fecha" => "2018" "volumen" => "134" "paginaInicial" => "79" "paginaFinal" => "85" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/29413512" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0264410X13002429" "estado" => "S300" "issn" => "0264410X" ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib0050" "etiqueta" => "[10]" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The COPD comorbidome in the light of the degree of dyspnea and risk of exacerbation" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "J.M. Figueira Gonçalves" 1 => "M.Á García Bello" 2 => "M.D. Martín Martínez" 3 => "L.I. Pérez Méndez" 4 => "I. García-Talavera" 5 => "S. García Hernández" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "COPD" "fecha" => "2019" "volumen" => "16" "paginaInicial" => "104" "paginaFinal" => "107" ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib0055" "etiqueta" => "[11]" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Comorbidity, systemic inflammation and outcomes in the ECLIPSE cohort" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "J. Miller" 1 => "L.D. Edwards" 2 => "A. Agustí" 3 => "P. Bakke" 4 => "P.M. Calverley" 5 => "B. Celli" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.rmed.2013.05.001" "Revista" => array:6 [ "tituloSerie" => "Respir Med." "fecha" => "2013" "volumen" => "107" "paginaInicial" => "1376" "paginaFinal" => "1384" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23791463" "web" => "Medline" ] ] ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib0060" "etiqueta" => "[12]" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Exacerbations of Chronic Obstructive Pulmonary Disease and Cardiac Events. A Post Hoc Cohort Analysis from the SUMMIT Randomized Clinical Trial" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "K.M. Kunisaki" 1 => "M.T. Dransfield" 2 => "J.A. Anderson" 3 => "R.D. Brook" 4 => "P.M.A. Calverley" 5 => "B.R. Celli" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/rccm.201711-2239OC" "Revista" => array:6 [ "tituloSerie" => "Am J Respir Crit Care Med." "fecha" => "2018" "volumen" => "198" "paginaInicial" => "51" "paginaFinal" => "57" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/29442524" "web" => "Medline" ] ] ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib0065" "etiqueta" => "[13]" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Impact of 13-valent pneumococcal conjugate polysaccharide vaccination on severe exacerbations in patients with chronic obstructive pulmonary disease and established cardiovascular disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "J.M. Figueira Gonçalves" 1 => "M.A. García Bello" 2 => "N. Bethencourt Martín" 3 => "D. Díaz Pérez" 4 => "L.I. Pérez-Méndez" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.ejim.2019.03.010" "Revista" => array:6 [ "tituloSerie" => "Eur J Intern Med." "fecha" => "2019" "volumen" => "63" "paginaInicial" => "e14" "paginaFinal" => "e16" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/30904432" "web" => "Medline" ] ] ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib0070" "etiqueta" => "[14]" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Comorbidities and risk of mortality in patients with chronic obstructive pulmonary disease" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "M. Divo" 1 => "C. Cote" 2 => "J.P. de Torres" 3 => "C. Casanova" 4 => "J.M. Marin" 5 => "V. Pinto-Plata" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/rccm.201201-0034OC" "Revista" => array:6 [ "tituloSerie" => "Am J Respir Crit Care Med." "fecha" => "2012" "volumen" => "186" "paginaInicial" => "155" "paginaFinal" => "161" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22561964" "web" => "Medline" ] ] ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib0075" "etiqueta" => "[15]" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Can the COPD-comorbidome be applied to all outpatients with chronic obstructive pulmonary disease? A Single-center Analysis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "J.M. Figueira Gonçalves" 1 => "M.A. García Bello" 2 => "M.D. Martín Martínez" 3 => "I. García-Talavera" 4 => "R. Golpe" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:3 [ "tituloSerie" => "Arch Bronconeumol." "fecha" => "2019" "itemHostRev" => array:3 [ "pii" => "S0735109707011990" "estado" => "S300" "issn" => "07351097" ] ] ] ] ] ] ] ] ] ] ] "agradecimientos" => array:1 [ 0 => array:4 [ "identificador" => "xack443457" "titulo" => "Acknowledgements" "texto" => "<p id="par0040" class="elsevierStylePara elsevierViewall">My thanks go to all my colleagues and friends who have supported me in my efforts to characterize the COPD population in the Canary Islands, and I also thank Violeta Ferrer for her illustration.</p>" "vista" => "all" ] ] ] "idiomaDefecto" => "en" "url" => "/15792129/0000005600000001/v3_202001222229/S157921291930357X/v3_202001222229/en/main.assets" "Apartado" => array:4 [ "identificador" => "49861" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Scientific letters" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/15792129/0000005600000001/v3_202001222229/S157921291930357X/v3_202001222229/en/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S157921291930357X?idApp=UINPBA00003Z" ]
Year/Month | Html | Total | |
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2024 November | 2 | 0 | 2 |
2024 October | 39 | 22 | 61 |
2024 September | 35 | 18 | 53 |
2024 August | 71 | 36 | 107 |
2024 July | 39 | 22 | 61 |
2024 June | 44 | 25 | 69 |
2024 May | 60 | 25 | 85 |
2024 April | 37 | 22 | 59 |
2024 March | 50 | 26 | 76 |
2024 February | 53 | 16 | 69 |
2023 December | 1 | 2 | 3 |
2023 March | 11 | 5 | 16 |
2023 February | 29 | 23 | 52 |
2023 January | 24 | 24 | 48 |
2022 December | 38 | 27 | 65 |
2022 November | 55 | 19 | 74 |
2022 October | 43 | 41 | 84 |
2022 September | 27 | 15 | 42 |
2022 August | 31 | 35 | 66 |
2022 July | 30 | 37 | 67 |
2022 June | 29 | 34 | 63 |
2022 May | 34 | 32 | 66 |
2022 April | 29 | 25 | 54 |
2022 March | 30 | 31 | 61 |
2022 February | 30 | 31 | 61 |
2022 January | 29 | 39 | 68 |
2021 April | 1 | 0 | 1 |
2020 April | 1 | 0 | 1 |
2020 March | 4 | 0 | 4 |