Scientific Letter
Primary Pulmonary Hemangiopericytoma
Hemangiopericitoma pulmonar primario
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Chest ultrasound showing abundant septa preventing drainage of pleural fluid (A). A single dose of 100<span class="elsevierStyleHsp" style=""></span>000<span class="elsevierStyleHsp" style=""></span>IU urokinase was instilled and left to act for 2<span class="elsevierStyleHsp" style=""></span>h; the thoracic ultrasound was then repeated, revealing pleural effusion containing detritus and lysis of the septa (B). The effusion was than drained, obtaining 750<span class="elsevierStyleHsp" style=""></span>ml of serosanguineous pleural fluid and subsequent symptomatic improvement.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Julia Herrero Huertas, Francisco Julián López González, Lucía García Alfonso, Ana Isabel Enríquez Rodríguez" "autores" => array:4 [ 0 => array:2 [ "nombre" => "Julia" "apellidos" => "Herrero Huertas" ] 1 => array:2 [ "nombre" => "Francisco Julián" "apellidos" => "López González" ] 2 => array:2 [ "nombre" => "Lucía" "apellidos" => "García Alfonso" ] 3 => array:2 [ "nombre" => "Ana Isabel" "apellidos" => "Enríquez Rodríguez" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0300289619302157" "doi" => "10.1016/j.arbres.2019.04.002" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289619302157?idApp=UINPBA00003Z" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212919302563?idApp=UINPBA00003Z" "url" => "/15792129/0000005500000011/v1_201911020900/S1579212919302563/v1_201911020900/en/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S1579212919302988" "issn" => "15792129" "doi" => "10.1016/j.arbr.2019.10.003" "estado" => "S300" "fechaPublicacion" => "2019-11-01" "aid" => "2138" "copyright" => "SEPAR" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "crp" "cita" => "Arch Bronconeumol. 2019;55:591-3" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 3 "formatos" => array:2 [ "HTML" => 1 "PDF" => 2 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Scientific Letter</span>" "titulo" => "Can the COPD-comorbidome Be Applied to All Outpatients With Chronic Obstructive Pulmonary Disease? A Single-center Analysis" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "591" "paginaFinal" => "593" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "¿El comorbidoma de COPD se puede aplicar a todos los pacientes ambulatorios con enfermedad pulmonar obstructiva crónica? Un estudio unicéntrico" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1691 "Ancho" => 2083 "Tamanyo" => 145087 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">The “comorbidome” is a graphic expression of comorbities with more than 5% prevalence in the entire cohort. The area of the circles relates to the prevalence of the disease. The proximity to the center (mortality) express the strength of the association between the disease and the risk of death. This was scaled from the inverse of the HR (1/HR). The dotted line represents HR<span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>1. Beyond the line, HR are less than 1. The red bubble represents statistical significance association (HR<span class="elsevierStyleHsp" style=""></span>><span class="elsevierStyleHsp" style=""></span>1; <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span><<span class="elsevierStyleHsp" style=""></span>.05). <span class="elsevierStyleItalic">Abbreviations</span>: HF: heart failure. CKD: chronic kidney disease. IHD: ischemic heart disease. CVA: cerebrovascular accidents. DM: diabetes mellitus. DLP: dyslipidemia. PADs: peripheral arterial disease.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Juan Marco Figueira Gonçalves, Miguel Ángel García Bello, María Dolores Martín Martínez, Ignacio García-Talavera, Rafael Golpe" "autores" => array:5 [ 0 => array:2 [ "nombre" => "Juan Marco" "apellidos" => "Figueira Gonçalves" ] 1 => array:2 [ "nombre" => "Miguel Ángel" "apellidos" => "García Bello" ] 2 => array:2 [ "nombre" => "María Dolores" "apellidos" => "Martín Martínez" ] 3 => array:2 [ "nombre" => "Ignacio" "apellidos" => "García-Talavera" ] 4 => array:2 [ "nombre" => "Rafael" "apellidos" => "Golpe" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212919302988?idApp=UINPBA00003Z" "url" => "/15792129/0000005500000011/v1_201911020900/S1579212919302988/v1_201911020900/en/main.assets" ] "en" => array:15 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Scientific Letter</span>" "titulo" => "Primary Pulmonary Hemangiopericytoma" "tieneTextoCompleto" => true "saludo" => "<span class="elsevierStyleItalic">Dear Editor:</span>" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "593" "paginaFinal" => "594" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "José María Hernández Pérez, Lorenzo Pérez Negrín, Claudia Viviana López Charry" "autores" => array:3 [ 0 => array:4 [ "nombre" => "José María" "apellidos" => "Hernández Pérez" "email" => array:1 [ 0 => "jmherper@hotmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "*" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "Lorenzo" "apellidos" => "Pérez Negrín" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "Claudia Viviana" "apellidos" => "López Charry" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Sección de Neumología, Hospital General de La Palma, Breña Alta, La Palma, Santa Cruz de Tenerife, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicio de Neumología, Hospital Universitario Nuestra Señora de Candelaria, Santa Cruz de Tenerife, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Hemangiopericitoma pulmonar primario" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 790 "Ancho" => 750 "Tamanyo" => 80507 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Image obtained during bronchoscopy highlighting the presence of a polylobulated tumor at the entrance to the left main bronchus.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">The high prevalence of epithelial lung tumors means that mesenchymal lung tumors are rarities seen very occasionally in routine clinical practice. We report the case of a patient referred to the respiratory medicine clinic for the study of recurrent self-limiting episodes of bloody expectoration.</p><p id="par0010" class="elsevierStylePara elsevierViewall">This was a female patient, 56 years of age, originally from Venezuela, who presented due to repeated self-limiting episodes of expectoration of blood while coughing, not affecting hemodynamic parameters, blood gases, or blood counts. Four years previously in her home country, she had been diagnosed on CT with a prevertebral solid tumor, determined on thoracotomy to be thoracic hemangioma, that was treated by radiation therapy (total dose unknown). Other surgical history included left inguinal herniorrhaphy, hysterectomy, and double adnexectomy. Physical examination was unremarkable, and both complete blood count and biochemistry results were within normal ranges. Chest X-ray showed the presence of a round subcarinal lesion. CT confirmed the presence of a mass enhanced by administration of contrast medium, measuring about 8.5×4.5<span class="elsevierStyleHsp" style=""></span>cm in diameter, located immediately behind the right pulmonary artery and accompanied by paraaortic and retroperitoneal lymphadenopathies.</p><p id="par0015" class="elsevierStylePara elsevierViewall">Fiberoptic bronchoscopy (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>) showed a purplish mass with a polylobulated surface located in the main carina, almost entirely occluding the entrance to the left main bronchus, but that did not prevent passage of the bronchoscope. The appearance of the endobronchial lesion and the patient's history of an intrathoracic vascular lesion made the collection of endoscopic biopsies inadvisable. Some days later, rigid bronchoscopy was performed under general anesthesia, and biopsies were collected, complicated by severe bleeding controlled with diathermy, followed by arteriography with embolization of the branches feeding the right bronchial artery. Biopsy samples showed the presence of numerous endothelized vessels with fibrous walls and a dense proliferation of cells with elongated nuclei arranged in bundles with variable spatial arrangement with no necrosis or mitosis, that were positive for markers CD34 and CD31, Ki-67 in less than 5%, and negative for epithelial and muscle markers; these findings were consistent with pulmonary hemangiopericytoma.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0020" class="elsevierStylePara elsevierViewall">Between 2% and 6% of all primary mediastinal tumors are of mesenchymal origin. Of these, hemangiopericytoma is a rarity: it originates in the Zimmermann pericytes, which form part of the outer layer surrounding the endothelium of the capillaries and is now classified as perivascular tumor. It represents less than 2% of all soft tissue sarcomas,<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">1</span></a> and approximately 1% of all tumors of vascular origin.<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">2</span></a> The main sites tend to be the muscle tissue of the limbs, subcutaneous tissue, and the retroperitoneum. The chest (usually mediastinal) as the primary site of hemangiopericytoma is extremely rare, as attested by a review of literature which retrieved very few cases.<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">3</span></a> Published cases of pulmonary involvement mostly began as solitary pulmonary nodules, and to our knowledge, this is the first case with endobronchial expression evidenced by bronchoscopy.</p><p id="par0025" class="elsevierStylePara elsevierViewall">This type of tumor usually begins with a wide variety of symptoms, which most notably include hemoptysis.<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">4</span></a> Image testing, especially CT with and without contrast and magnetic resonance imaging (MRI),<a class="elsevierStyleCrossRefs" href="#bib0045"><span class="elsevierStyleSup">1,2</span></a> helps to visualize the lesion and point to its vascular origin, although these tests are not diagnostic in themselves.</p><p id="par0030" class="elsevierStylePara elsevierViewall">Pericytomas tend to behave unpredictably.<a class="elsevierStyleCrossRefs" href="#bib0065"><span class="elsevierStyleSup">5,6</span></a> In the case of our patient, after the initial diagnosis of angioma, the lesion grew slowly without showing any clinical signs or symptoms that would suggest malignancy. Findings that suggest a more aggressive behavior are: size greater than 10<span class="elsevierStyleHsp" style=""></span>cm (with a 66% probability of metastasis), the existence of more than 3 mitoses per field, necrosis, pleural invasion, and vascular invasion.<a class="elsevierStyleCrossRef" href="#bib0075"><span class="elsevierStyleSup">7</span></a> In our case, despite the size of the lesion (8.5×4.5<span class="elsevierStyleHsp" style=""></span>cm), the absence of necrosis or mitosis on the pathology study suggested a lack of aggressive behavior up to the time of diagnosis. It is clear however that, since it was a large central endobronchial vascular tumor, the risk of potentially fatal local complications was high.</p><p id="par0035" class="elsevierStylePara elsevierViewall">Treatment of tumors of this type is based primarily on surgical resection of the lesion, if possible.<a class="elsevierStyleCrossRef" href="#bib0080"><span class="elsevierStyleSup">8</span></a> Prior embolization of the feeder arterial branches is always advisable. Postoperative radiation therapy also plays an important role in lesions of this type, while chemotherapy appears to have no clear benefit and is reserved for selected cases and always administered with palliative intent.</p><p id="par0040" class="elsevierStylePara elsevierViewall">In our case, the site of the lesion and the treatments received earlier ruled out surgical resection, so we opted for tumor embolization, implantation of a silicone Dumon Y stent, and external radiation therapy. This prosthesis had to be removed 6 months later due to intractable cough, after which successive bronchial dilation procedures were performed using rigid bronchoscopy, during the last of which massive bronchial bleeding occurred due to rupture of the tumor mass that resulted in the death of the patient.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Hernández Pérez JM, Pérez Negrín L, López Charry CV. Hemangiopericitoma pulmonar primario. Arch Bronconeumol. 2019;55:593–594.</p>" ] ] "multimedia" => array:1 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 790 "Ancho" => 750 "Tamanyo" => 80507 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Image obtained during bronchoscopy highlighting the presence of a polylobulated tumor at the entrance to the left main bronchus.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0015" "bibliografiaReferencia" => array:8 [ 0 => array:3 [ "identificador" => "bib0045" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Radiography, doppler sonography and MR angiography of malignant pulmonary hemangiopericytoma" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "E. Yilmaz" 1 => "A. Akkoclu" 2 => "A. Kargi" 3 => "C. Sevinc" 4 => "N. Komus" 5 => "H. Catalyurek" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.2214/ajr.181.4.1811079" "Revista" => array:6 [ "tituloSerie" => "AJR Am J Roentgenol" "fecha" => "2003" "volumen" => "181" "paginaInicial" => "1079" "paginaFinal" => "1081" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14500234" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0050" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "CT and features of primary pulmonary hemangiopericytomas" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "M. Halle" 1 => "U. Blum" 2 => "E. Dinkel" 3 => "W. Brugger" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Comput Assit Tomogr" "fecha" => "1993" "volumen" => "17" "paginaInicial" => "51" "paginaFinal" => "55" ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0055" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Primary pulmonary malignant hemangiopericytoma associated with coagulopathy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "Y.C. Wu" 1 => "L.S. Wang" 2 => "W. Chen" 3 => "H.J. Fahn" 4 => "M.H. Huang" 5 => "J. Whang-Peng" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/s0003-4975(97)00682-6" "Revista" => array:6 [ "tituloSerie" => "Ann Thorac Surg" "fecha" => "1997" "volumen" => "64" "paginaInicial" => "841" "paginaFinal" => "843" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9307488" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0060" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Primary pulmonary hemangiopericytoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "S.A. Yousem" 1 => "L. Hochholzer" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1002/1097-0142(19870201)59:3<549::aid-cncr2820590332>3.0.co;2-y" "Revista" => array:6 [ "tituloSerie" => "Cancer" "fecha" => "1987" "volumen" => "59" "paginaInicial" => "549" "paginaFinal" => "555" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3791163" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0065" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Primary malignant pulmonary hemangiopericytoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "D.S. Katz" 1 => "M.J. Lane" 2 => "A.N. Leung" 3 => "F.S. Marcus" 4 => "M.K. Sakata" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/s0899-7071(97)00118-6" "Revista" => array:6 [ "tituloSerie" => "Clin Imaging" "fecha" => "1998" "volumen" => "22" "paginaInicial" => "192" "paginaFinal" => "195" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9559231" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0070" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Primary pulmonary hemangiopericytoma: early local recurrence after perioperative rupture of the giant tumor mass (two cases)" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "H. Van Damme" 1 => "G. Dekoster" 2 => "E. Creemers" 3 => "G. Hermans" 4 => "R. limet" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Surgery" "fecha" => "1990" "volumen" => "108" "paginaInicial" => "105" "paginaFinal" => "109" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2360178" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0075" "etiqueta" => "7" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Massive pulmonary hemangiopericytoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "V.W. Rush" 1 => "W.P. Shuman" 2 => "R. Schmidt" 3 => "G.E. Laramore" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1002/1097-0142(19891101)64:9<1928::aid-cncr2820640928>3.0.co;2-y" "Revista" => array:6 [ "tituloSerie" => "Cancer" "fecha" => "1989" "volumen" => "64" "paginaInicial" => "1928" "paginaFinal" => "1936" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2790703" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib0080" "etiqueta" => "8" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Recurrent haemoptysis in a young woman: a case of a malignant hemangiopericytoma of the lung" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "T.B. Rothe" 1 => "W. Karrer" 2 => "J.-O. gebbers" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1136/thx.49.2.188" "Revista" => array:6 [ "tituloSerie" => "Thorax" "fecha" => "1994" "volumen" => "49" "paginaInicial" => "188" "paginaFinal" => "189" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8128415" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15792129/0000005500000011/v1_201911020900/S1579212919302629/v1_201911020900/en/main.assets" "Apartado" => array:4 [ "identificador" => "49861" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Scientific letters" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/15792129/0000005500000011/v1_201911020900/S1579212919302629/v1_201911020900/en/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212919302629?idApp=UINPBA00003Z" ]
| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 8 | 3 | 11 |
| 2024 October | 68 | 19 | 87 |
| 2024 September | 54 | 15 | 69 |
| 2024 August | 76 | 37 | 113 |
| 2024 July | 41 | 20 | 61 |
| 2024 June | 54 | 26 | 80 |
| 2024 May | 65 | 28 | 93 |
| 2024 April | 28 | 30 | 58 |
| 2024 March | 41 | 22 | 63 |
| 2024 February | 30 | 21 | 51 |
| 2023 March | 7 | 4 | 11 |
| 2023 February | 31 | 28 | 59 |
| 2023 January | 32 | 35 | 67 |
| 2022 December | 64 | 25 | 89 |
| 2022 November | 59 | 35 | 94 |
| 2022 October | 55 | 37 | 92 |
| 2022 September | 44 | 14 | 58 |
| 2022 August | 74 | 42 | 116 |
| 2022 July | 69 | 37 | 106 |
| 2022 June | 26 | 30 | 56 |
| 2022 May | 36 | 37 | 73 |
| 2022 April | 39 | 31 | 70 |
| 2022 March | 32 | 36 | 68 |
| 2022 February | 34 | 32 | 66 |
| 2022 January | 28 | 26 | 54 |
| 2021 December | 33 | 40 | 73 |
| 2021 November | 30 | 44 | 74 |
| 2020 April | 1 | 0 | 1 |
| 2020 March | 1 | 0 | 1 |
| 2019 November | 1 | 0 | 1 |
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