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A)<span class="elsevierStyleHsp" style=""></span>Ti neural mayor que el Ti del ventilador, objetivándose asincronía del tipo doble <span class="elsevierStyleItalic">trigger</span>. B)<span class="elsevierStyleHsp" style=""></span>Ti neural menor que el Ti del ventilador, objetivándose asincronía del tipo inspiración prolongada. C)<span class="elsevierStyleHsp" style=""></span>Ti ajustado con correcto acoplamiento al ventilador. D)<span class="elsevierStyleHsp" style=""></span>Correlación lineal entre el Ti neural y Ti ajustado obtenido con el método de barrido.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Julia Herrero Huertas, Francisco Laso del Hierro, Fernando Peláez Castro, Cristina Plaza Moreno, Ana Ampuero López, María del Pilar Carballosa de Miguel, Sarah Heili Frades, Germán Peces-Barba Romero" "autores" => array:8 [ 0 => array:2 [ "nombre" => "Julia" "apellidos" => "Herrero Huertas" ] 1 => array:2 [ "nombre" => "Francisco" "apellidos" => "Laso del Hierro" ] 2 => array:2 [ "nombre" => "Fernando" "apellidos" => "Peláez Castro" ] 3 => array:2 [ "nombre" => "Cristina" "apellidos" => "Plaza Moreno" ] 4 => array:2 [ "nombre" => "Ana" "apellidos" => "Ampuero López" ] 5 => array:2 [ "nombre" => "María del Pilar" "apellidos" => "Carballosa de Miguel" ] 6 => array:2 [ "nombre" => "Sarah" "apellidos" => "Heili Frades" ] 7 => array:2 [ "nombre" => "Germán" "apellidos" => "Peces-Barba Romero" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S1579212919301557" "doi" => "10.1016/j.arbr.2019.02.006" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212919301557?idApp=UINPBA00003Z" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289619300924?idApp=UINPBA00003Z" "url" => "/03002896/0000005500000008/v2_201908080730/S0300289619300924/v2_201908080730/es/main.assets" ] ] "itemSiguiente" => array:19 [ "pii" => "S1579212919302083" "issn" => "15792129" "doi" => "10.1016/j.arbr.2018.11.023" "estado" => "S300" "fechaPublicacion" => "2019-08-01" "aid" => "2052" "copyright" => "SEPAR" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "crp" "cita" => "Arch Bronconeumol. 2019;55:445-6" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 24 "formatos" => array:3 [ "EPUB" => 5 "HTML" => 11 "PDF" => 8 ] ] "en" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Scientific Letter</span>" "titulo" => "Influenza and Pneumococcal Vaccination in Chronic Respiratory Patients – Are We in the Right Path?" 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"b" "identificador" => "aff0010" ] 2 => array:3 [ "entidad" => "Servicio de Neumología, Hospital Universitario Clínico San Carlos, Madrid, Spain" "etiqueta" => "c" "identificador" => "aff0015" ] 3 => array:3 [ "entidad" => "Servicio de Neumología, Hospital Universitario La Paz, Madrid, Spain" "etiqueta" => "d" "identificador" => "aff0020" ] 4 => array:3 [ "entidad" => "Servicio de Neumología, Hospital Universitario de Guadalajara, Guadalajara, Spain" "etiqueta" => "e" "identificador" => "aff0025" ] 5 => array:3 [ "entidad" => "Unidad de Cuidados Intermedios Respiratorios, Servicio de Neumología, IIS-Fundación Jiménez Díaz Quirón salud, UAM, Madrid, Spain" "etiqueta" => "f" "identificador" => "aff0030" ] 6 => array:3 [ "entidad" => "Ciberes (Centro de investigaciones Biomédica en Red de Enfermedades respiratorias), REVA (Réseau Européen de Ventilation Artificielle)" "etiqueta" => "g" "identificador" => "aff0035" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Importancia del manejo especializado en el destete prolongado" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1780 "Ancho" => 2093 "Tamanyo" => 178689 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Sweep procedure to calculate neural inspiratory time (Ti). (A) Neural Ti greater than ventilator Ti, demonstrating double-trigger asynchrony. (B) Neural Ti less than ventilator Ti, demonstrating prolonged inspiration asynchrony. (C) Adjusted Ti with correct adjustment to ventilator. (D) Linear correlation between neural Ti and adjusted Ti obtained with the sweep method.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Difficulties associated with disconnecting patients from mechanical ventilation and decannulation after prolonged ventilation are well documented. In most patients (70%), weaning is simple, but it is difficult in 15%, and prolonged in another 15%.<a class="elsevierStyleCrossRefs" href="#bib0075"><span class="elsevierStyleSup">1,2</span></a> In this last group, it is important to provide global, specialized management.</p><p id="par0010" class="elsevierStylePara elsevierViewall">We report the case of a 50-year-old woman admitted to the intensive care unit (ICU) for 1.5 months after surgical resection of an occipital arteriovenous malformation. Because of the weaning difficulties experienced by this unit, the patient was transferred to an intermediate respiratory care unit (IRCU), where the following mechanical ventilation weaning and decannulation protocol was implemented<a class="elsevierStyleCrossRef" href="#bib0085"><span class="elsevierStyleSup">3</span></a>:</p><p id="par0015" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleItalic">Phase 1. Assess the global situation</span></p><p id="par0020" class="elsevierStylePara elsevierViewall">The patient had a prolonged stay in the ICU due to difficult-to-control focal epilepsy after surgery, which led to prolonged connection to invasive mechanical ventilation (IMV), with surgical tracheostomy performed at 2 weeks. Complications included IMV-related pneumonia<a class="elsevierStyleCrossRef" href="#bib0090"><span class="elsevierStyleSup">4</span></a> and severe critical illness polyneuromyopathy.<a class="elsevierStyleCrossRef" href="#bib0095"><span class="elsevierStyleSup">5</span></a> She required high positive end-expiratory pressures (PEEP) (20–25<span class="elsevierStyleHsp" style=""></span>cmH<span class="elsevierStyleInf">2</span>O) to maintain adequate alveolar recruitment. On arrival at the IRCU, she was totally ventilator-dependent, with pressure support (PS) ventilation (PEEP: 12, PS: 8, FiO<span class="elsevierStyleInf">2</span>: 60%).</p><p id="par0025" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleItalic">Phase 2. Assess the feasibility of spontaneous ventilation</span></p><p id="par0030" class="elsevierStylePara elsevierViewall">The spontaneous ventilation test failed, due to a low respiratory drive, severe malacia that made it impossible to decrease PEEP due to collapse, a lack of cough effort, and severe diaphragmatic dysfunction, confirmed by chest ultrasound.<a class="elsevierStyleCrossRefs" href="#bib0100"><span class="elsevierStyleSup">6,7</span></a> Mucociliary clearance techniques began with respiratory physiotherapy, postural changes, active humidification systems aimed at reducing the viscosity of secretions, and regular aspiration of secretions 2–3 times every 8<span class="elsevierStyleHsp" style=""></span>h, using a 12 CH suction tube.<a class="elsevierStyleCrossRefs" href="#bib0110"><span class="elsevierStyleSup">8,9</span></a></p><p id="par0035" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleItalic">Phase 3. Choice of ventilation mode</span></p><p id="par0040" class="elsevierStylePara elsevierViewall">As mentioned above, we decided to switch to pressure control mode until the respiratory drive improved, requiring a fixed inspiratory time (Ti), adjusted to the patient's neural Ti.<a class="elsevierStyleCrossRef" href="#bib0120"><span class="elsevierStyleSup">10</span></a> With the aim of avoiding asynchronies (prolonged inspirations and double triggering), the sweep procedure was performed, consisting of increasing and/or decreasing the Ti of the ventilator until the one that is best suited to the patient was determined (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>A–C).</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0045" class="elsevierStylePara elsevierViewall">In addition to motor and respiratory physiotherapy, diaphragm muscle training sessions were conducted to address the problem of diaphragm dysfunction: the patient was connected for short periods of time to incremental pressure triggering, since this has been shown to increase the mechanical load more than flow triggering.<a class="elsevierStyleCrossRef" href="#bib0125"><span class="elsevierStyleSup">11</span></a> After several sessions, diaphragmatic excursion improved, and respiratory drive and cough strength increased. Given the patient's clinical and mechanical progress, we decided to move forward and resume pressure support ventilation.</p><p id="par0050" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleItalic">Phase 4. Assess tracheal integrity by performing a cuff leak test</span></p><p id="par0055" class="elsevierStylePara elsevierViewall">A cuff leak test<a class="elsevierStyleCrossRef" href="#bib0130"><span class="elsevierStyleSup">12</span></a> was performed, which was positive, with a difference in exhaled tidal volume of greater than 130<span class="elsevierStyleHsp" style=""></span>ml.</p><p id="par0060" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleItalic">Phases 4–7. Change of cannula and progressive closure</span></p><p id="par0065" class="elsevierStylePara elsevierViewall">The cannula was initially substituted with a cannula with fenestra, which was closed for periods of 1–2<span class="elsevierStyleHsp" style=""></span>h. High flow nasal prongs were used during closure periods, given their benefits in controlling malacia and decreasing airway resistance. In parallel with clinical improvement, the need to aspirate secretions diminished until an effective cough was achieved.</p><p id="par0070" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleItalic">Phases 8–11. Placement of hemi-cannula, closure, and withdrawal</span></p><p id="par0075" class="elsevierStylePara elsevierViewall">After checking tolerance to cannula closures for periods longer than 4–6<span class="elsevierStyleHsp" style=""></span>h and confirming adaptation to and effectiveness of non-invasive mechanical ventilation (NIMV), we proceeded to place a hemi-cannula with cap, which was withdrawn 3–4 days later, with no complications. After successfully completing this protocol, the patient was transferred to the Department of Neurosurgery, where she continued to receive NIMV sessions without further incidents.</p><p id="par0080" class="elsevierStylePara elsevierViewall">The sweep method used in this case is not described in the scientific literature, so a double-blind simulation of this procedure was performed. This was done using a lung simulator,<a class="elsevierStyleCrossRef" href="#bib0135"><span class="elsevierStyleSup">13</span></a> in which a first operator sets a neural Ti and a second operator ventilates the simulator in pressure control mode and uses the sweep method to determine neural Ti. The procedure is repeated with different neural Ti values (<span class="elsevierStyleItalic">n</span>=12). Correlation using simple linear regression between the two Tis was <span class="elsevierStyleItalic">R</span><span class="elsevierStyleSup">2</span>=0.9, <span class="elsevierStyleItalic">P</span><.0001 (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>D). In accordance with this result, we believe that this procedure can offer new possibilities in the neural control of ventilation in controlled modes.</p><p id="par0085" class="elsevierStylePara elsevierViewall">It also raises the possibility of using high flow during closures with tracheotomy to manage tracheal malacia, given the advantages of this approach in the pressurization of the upper airway.<a class="elsevierStyleCrossRef" href="#bib0140"><span class="elsevierStyleSup">14</span></a></p><p id="par0090" class="elsevierStylePara elsevierViewall">We also describe a new modality of diaphragm training based on the use of pressure triggering, a method that has been abandoned in routine practice due to the greater work of breathing than observed with flow triggering. However, in our patient we took advantage of this effect to train the diaphragmatic muscle, monitor its activity by ultrasound, and control the risk of muscle fatigue (ineffective effort).</p><p id="par0095" class="elsevierStylePara elsevierViewall">In conclusion, we highlight the relevance of the use of the sweep method in the neural control of ventilation and highlight the importance of having a highly specialized environment where a comprehensive protocol can be implemented for the management of patients with highly complex respiratory problems, such as prolonged weaning.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Herrero Huertas J, Laso del Hierro F, Peláez Castro F, Plaza Moreno C, Ampuero López A, Carballosa de Miguel MP, et al. Importancia del manejo especializado en el destete prolongado. Arch Bronconeumol. 2019;55:443–444.</p>" ] ] "multimedia" => array:1 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1780 "Ancho" => 2093 "Tamanyo" => 178689 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Sweep procedure to calculate neural inspiratory time (Ti). (A) Neural Ti greater than ventilator Ti, demonstrating double-trigger asynchrony. (B) Neural Ti less than ventilator Ti, demonstrating prolonged inspiration asynchrony. (C) Adjusted Ti with correct adjustment to ventilator. (D) Linear correlation between neural Ti and adjusted Ti obtained with the sweep method.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0015" "bibliografiaReferencia" => array:14 [ 0 => array:3 [ "identificador" => "bib0075" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Epidemiology of weaning outcome according to a new definition the WIND study" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "G. Béduneau" 1 => "T. Pham" 2 => "F. Schortgen" 3 => "L. Piquilloud" 4 => "E. Zogheib" 5 => "M. 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Year/Month | Html | Total | |
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2024 November | 6 | 5 | 11 |
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2024 May | 73 | 30 | 103 |
2024 April | 26 | 23 | 49 |
2024 March | 28 | 19 | 47 |
2024 February | 23 | 25 | 48 |
2023 October | 1 | 1 | 2 |
2023 July | 1 | 0 | 1 |
2023 June | 1 | 0 | 1 |
2023 March | 16 | 2 | 18 |
2023 February | 49 | 19 | 68 |
2023 January | 38 | 24 | 62 |
2022 December | 72 | 26 | 98 |
2022 November | 56 | 19 | 75 |
2022 October | 63 | 30 | 93 |
2022 September | 49 | 19 | 68 |
2022 August | 38 | 42 | 80 |
2022 July | 30 | 46 | 76 |
2022 June | 26 | 30 | 56 |
2022 May | 28 | 37 | 65 |
2022 April | 34 | 29 | 63 |
2022 March | 35 | 33 | 68 |
2022 February | 31 | 22 | 53 |
2022 January | 29 | 33 | 62 |
2021 December | 25 | 43 | 68 |
2021 November | 34 | 36 | 70 |
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2021 September | 30 | 44 | 74 |
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2020 July | 1 | 0 | 1 |
2020 April | 4 | 2 | 6 |
2020 March | 32 | 6 | 38 |
2020 February | 81 | 11 | 92 |
2020 January | 5 | 0 | 5 |