array:24 [
  "pii" => "S1579212918300831"
  "issn" => "15792129"
  "doi" => "10.1016/j.arbr.2017.10.023"
  "estado" => "S300"
  "fechaPublicacion" => "2018-05-01"
  "aid" => "1763"
  "copyright" => "SEPAR"
  "copyrightAnyo" => "2017"
  "documento" => "simple-article"
  "crossmark" => 1
  "subdocumento" => "cor"
  "cita" => "Arch Bronconeumol. 2018;54:297"
  "abierto" => array:3 [
    "ES" => false
    "ES2" => false
    "LATM" => false
  ]
  "gratuito" => false
  "lecturas" => array:2 [
    "total" => 998
    "formatos" => array:3 [
      "EPUB" => 131
      "HTML" => 578
      "PDF" => 289
    ]
  ]
  "Traduccion" => array:1 [
    "es" => array:19 [
      "pii" => "S030028961730409X"
      "issn" => "03002896"
      "doi" => "10.1016/j.arbres.2017.10.017"
      "estado" => "S300"
      "fechaPublicacion" => "2018-05-01"
      "aid" => "1763"
      "copyright" => "SEPAR"
      "documento" => "simple-article"
      "crossmark" => 1
      "subdocumento" => "cor"
      "cita" => "Arch Bronconeumol. 2018;54:297"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 1355
        "formatos" => array:3 [
          "EPUB" => 130
          "HTML" => 782
          "PDF" => 443
        ]
      ]
      "es" => array:10 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Carta al Director</span>"
        "titulo" => "Comentarios al tratamiento de la tuberculosis con resistencia"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "paginas" => array:1 [
          0 => array:1 [
            "paginaInicial" => "297"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Comments On The Treatment Of Resistant Tuberculosis"
          ]
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "Jos&#233; Francisco Pascual Pareja"
            "autores" => array:1 [
              0 => array:2 [
                "nombre" => "Jos&#233; Francisco"
                "apellidos" => "Pascual Pareja"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S1579212918300831"
          "doi" => "10.1016/j.arbr.2017.10.023"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => false
            "ES2" => false
            "LATM" => false
          ]
          "gratuito" => false
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212918300831?idApp=UINPBA00003Z"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S030028961730409X?idApp=UINPBA00003Z"
      "url" => "/03002896/0000005400000005/v1_201805020858/S030028961730409X/v1_201805020858/es/main.assets"
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S1579212918300892"
    "issn" => "15792129"
    "doi" => "10.1016/j.arbr.2018.03.001"
    "estado" => "S300"
    "fechaPublicacion" => "2018-05-01"
    "aid" => "1805"
    "copyright" => "SEPAR"
    "documento" => "simple-article"
    "crossmark" => 1
    "subdocumento" => "cor"
    "cita" => "Arch Bronconeumol. 2018;54:298"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 1077
      "formatos" => array:3 [
        "EPUB" => 154
        "HTML" => 599
        "PDF" => 324
      ]
    ]
    "en" => array:10 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>"
      "titulo" => "Comments on the SEPAR Guidelines for the Diagnosis and Treatment of Drug-Resistant Tuberculosis"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:1 [
          "paginaInicial" => "298"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Comentarios a la normativa SEPAR de diagn&#243;stico y tratamiento de la tuberculosis con resistencia a f&#225;rmacos"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Jos&#233; A&#46; Caminero, Joan A&#46; Cayl&#225;, Jos&#233;-Mar&#237;a Garc&#237;a-Garc&#237;a, Francisco J&#46; Garc&#237;a-P&#233;rez, Juan J&#46; Palacios, Juan Ruiz-Manzano"
          "autores" => array:6 [
            0 => array:2 [
              "nombre" => "Jos&#233; A&#46;"
              "apellidos" => "Caminero"
            ]
            1 => array:2 [
              "nombre" => "Joan A&#46;"
              "apellidos" => "Cayl&#225;"
            ]
            2 => array:2 [
              "nombre" => "Jos&#233;-Mar&#237;a"
              "apellidos" => "Garc&#237;a-Garc&#237;a"
            ]
            3 => array:2 [
              "nombre" => "Francisco J&#46;"
              "apellidos" => "Garc&#237;a-P&#233;rez"
            ]
            4 => array:2 [
              "nombre" => "Juan J&#46;"
              "apellidos" => "Palacios"
            ]
            5 => array:2 [
              "nombre" => "Juan"
              "apellidos" => "Ruiz-Manzano"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0300289618300139"
        "doi" => "10.1016/j.arbres.2017.12.015"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289618300139?idApp=UINPBA00003Z"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212918300892?idApp=UINPBA00003Z"
    "url" => "/15792129/0000005400000005/v1_201804290447/S1579212918300892/v1_201804290447/en/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S1579212918300880"
    "issn" => "15792129"
    "doi" => "10.1016/j.arbr.2017.09.019"
    "estado" => "S300"
    "fechaPublicacion" => "2018-05-01"
    "aid" => "1756"
    "copyright" => "SEPAR"
    "documento" => "simple-article"
    "crossmark" => 1
    "subdocumento" => "crp"
    "cita" => "Arch Bronconeumol. 2018;54:295-6"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 1163
      "formatos" => array:3 [
        "EPUB" => 127
        "HTML" => 725
        "PDF" => 311
      ]
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Scientific Letter</span>"
      "titulo" => "Pulmonary Lesions&#58; Cause or Consequence of Respiratory Infection&#63;"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "295"
          "paginaFinal" => "296"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Lesi&#243;n pulmonar&#58; &#191;causa o consecuencia de infecci&#243;n respiratoria&#63;"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Fig&#46; 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 1162
              "Ancho" => 2500
              "Tamanyo" => 237083
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">&#40;A&#41; PA chest X-ray&#58; unilocular air cyst in left lung base&#46; &#40;B&#41; Chest CT&#58; thin-walled air cavity in left lower lobe&#46; &#40;C&#41; PA chest X-ray&#58; increased density in right upper lobe of the lung&#46; No cystic lesion is observed&#46; &#40;D&#41; PA chest X-ray&#58; unilocular air cyst in right lung&#46; &#40;E&#41; PA chest X-ray&#58; increased density in right lung&#46; &#40;F&#41; Chest CT&#58; image of thin-walled unilocular cyst containing air&#44; located in the apical segment of the right lower lobe&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Javier Nogueira L&#243;pez, Laura D&#237;az Munilla, Natividad Viguria S&#225;nchez, Laura Moreno-Galarraga"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "Javier"
              "apellidos" => "Nogueira L&#243;pez"
            ]
            1 => array:2 [
              "nombre" => "Laura"
              "apellidos" => "D&#237;az Munilla"
            ]
            2 => array:2 [
              "nombre" => "Natividad"
              "apellidos" => "Viguria S&#225;nchez"
            ]
            3 => array:2 [
              "nombre" => "Laura"
              "apellidos" => "Moreno-Galarraga"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0300289617304027"
        "doi" => "10.1016/j.arbres.2017.09.017"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289617304027?idApp=UINPBA00003Z"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212918300880?idApp=UINPBA00003Z"
    "url" => "/15792129/0000005400000005/v1_201804290447/S1579212918300880/v1_201804290447/en/main.assets"
  ]
  "en" => array:13 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>"
    "titulo" => "Comments on the Treatment of Resistant Tuberculosis"
    "tieneTextoCompleto" => true
    "saludo" => "To the Editor&#44;"
    "paginas" => array:1 [
      0 => array:1 [
        "paginaInicial" => "297"
      ]
    ]
    "autores" => array:1 [
      0 => array:3 [
        "autoresLista" => "Jos&#233; Francisco Pascual Pareja"
        "autores" => array:1 [
          0 => array:3 [
            "nombre" => "Jos&#233; Francisco"
            "apellidos" => "Pascual Pareja"
            "email" => array:1 [
              0 => "josefrancisco&#46;pascual&#64;salud&#46;madrid&#46;org"
            ]
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:2 [
            "entidad" => "Servicio de Medicina Interna&#44; Unidad de Tuberculosis&#44; Complejo Hospitalario La Paz-Cantoblanco-Carlos III&#44; Madrid&#44; Spain"
            "identificador" => "aff0005"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Comentarios al tratamiento de la tuberculosis con resistencia"
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">I read with interest the guidelines published by Caminero et al&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a> on the diagnosis and treatment of drug-resistant tuberculosis&#46; I agree that according to the published evidence&#44; bedaquiline and delamanid should be considered essential components in the design of multidrug-resistant &#40;MDR&#41; tuberculosis treatment regimens&#44; as the authors set out in their rational classification and sequential use of anti-TB drugs for the design of a treatment regimen &#40;Caminero et al&#46;&#44; Table 3<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a>&#41;&#46; Indeed&#44; the 2016 WHO classification<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">2</span></a> should have included them in group C &#40;other core second-line drugs&#41; along with linezolid&#44; rather than in group D &#40;add-on agents&#44; not part of the core regimen&#41;&#46; Caminero et al&#46;&#44; however&#44; seem to give a greater theoretical than practical value to bedaquiline and delamanid&#44; as treatment regimens with these drugs are not recommended from the outset&#44; probably for the same reason that WHO included them in group D2&#58; these drugs are very costly&#46; Nevertheless&#44; it is important to bear in mind that some studies have shown that the inclusion of these expensive drugs in multi-resistant tuberculosis treatment is a cost-effective measure&#46;<a class="elsevierStyleCrossRefs" href="#bib0040"><span class="elsevierStyleSup">3&#44;4</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">These guidelines recommend that priority be given to the shorter 9&#8211;12 month regimen proposed by the WHO in 2016&#44; known as the &#8220;9-month Bangladesh regimen&#8221;&#44;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">2</span></a> for all patients with rifampicin or multiresistant tuberculosis who have not previously received fluoroquinolones &#40;FQ&#41; or second-line injectable drugs &#40;SLID&#41; or who can demonstrate sensitivity in vitro to these 2 classes of antibiotics&#46; The WHO also recommends that this regimen should not be used in patients with suspected or confirmed resistance to 1 or more drugs in a shorter regimen &#40;e&#46;g&#46;&#44; pyrazinamide&#41;&#44; apart from FQs and SLIDs&#46; Some studies have raised serious questions about the suitability of shorter regimens in certain regions of the world &#40;including some European countries&#41;&#44; due to the prevalent resistance patterns in those areas&#46;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">5</span></a> Moreover&#44; the shorter regimen should be avoided in patients with extrapulmonary disease and in pregnancy&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">2</span></a></p></span>"
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Pascual Pareja JF&#46; Comentarios al tratamiento de la tuberculosis con resistencia&#46; Arch Bronconeumol&#46; 2018&#59;54&#58;297&#46;</p>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0015"
          "bibliografiaReferencia" => array:5 [
            0 => array:3 [
              "identificador" => "bib0030"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Diagnosis and treatment of drug-resistant tuberculosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "J&#46;A&#46; Caminero"
                            1 => "J&#46;A&#46; Cayla"
                            2 => "J&#46;M&#46; Garc&#237;a-Garc&#237;a"
                            3 => "F&#46;J&#46; Garc&#237;a-P&#233;rez"
                            4 => "J&#46;J&#46; Palacios"
                            5 => "J&#46; Ruiz-Manzano"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.arbres.2017.02.006"
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Bronconeumol"
                        "fecha" => "2017"
                        "volumen" => "53"
                        "paginaInicial" => "501"
                        "paginaFinal" => "509"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/28359606"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "WHO treatment guidelines for drug-resistant tuberculosis&#46; 2016 update&#46; Available from&#58; <a id="intr0010" class="elsevierStyleInterRef" href="http://apps.who.int/iris/bitstream/10665/250125/1/9789241549639-eng.pdf?ua=1">http&#58;&#47;&#47;apps&#46;who&#46;int&#47;iris&#47;bitstream&#47;10665&#47;250125&#47;1&#47;9789241549639-eng&#46;pdf&#63;ua&#61;1</a> &#91;reviewed October 2016&#93;&#44; &#91;accessed 30&#46;09&#46;17&#93;&#46;"
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0040"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cost-effectiveness of adding novel or group 5 interventions to a background regimen for the treatment of multidrug-resistant tuberculosis in Germany"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "D&#46; Wirth"
                            1 => "R&#46; Dass"
                            2 => "R&#46; Hettle"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1186/s12913-017-2118-2"
                      "Revista" => array:5 [
                        "tituloSerie" => "BMC Health Serv Res"
                        "fecha" => "2017"
                        "volumen" => "17"
                        "paginaInicial" => "182"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/28270207"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0045"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cost-effectiveness of adding bedaquiline to drug regimens for the treatment of multidrug-resistant tuberculosis in the UK"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "L&#46;J&#46; Wolfson"
                            1 => "A&#46; Walker"
                            2 => "R&#46; Hettle"
                            3 => "X&#46; Lu"
                            4 => "C&#46; Kambili"
                            5 => "A&#46; Murungi"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1371/journal.pone.0120763"
                      "Revista" => array:5 [
                        "tituloSerie" => "PLOS ONE"
                        "fecha" => "2015"
                        "volumen" => "10"
                        "paginaInicial" => "e0120763"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25794045"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0050"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Limited benefit of the new shorter multidrug-resistant tuberculosis regimen in Europe"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "C&#46; Lange"
                            1 => "R&#46; Duarte"
                            2 => "M&#46; Fr&#233;chet-Jachym"
                            3 => "G&#46; Guenther"
                            4 => "L&#46; Guglielmetti"
                            5 => "I&#46;D&#46; Olaru"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1164/rccm.201606-1097LE"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Respir Crit Care Med"
                        "fecha" => "2016"
                        "volumen" => "194"
                        "paginaInicial" => "1029"
                        "paginaFinal" => "1031"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/27685538"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/15792129/0000005400000005/v1_201804290447/S1579212918300831/v1_201804290447/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "45358"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Letters to the Editor"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/15792129/0000005400000005/v1_201804290447/S1579212918300831/v1_201804290447/en/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212918300831?idApp=UINPBA00003Z"
]
Share
Journal Information

Statistics

Follow this link to access the full text of the article

Letter to the Editor
Comments on the Treatment of Resistant Tuberculosis
Comentarios al tratamiento de la tuberculosis con resistencia
José Francisco Pascual Pareja
Servicio de Medicina Interna, Unidad de Tuberculosis, Complejo Hospitalario La Paz-Cantoblanco-Carlos III, Madrid, Spain
Read
3819
Times
was read the article
1626
Total PDF
2193
Total HTML
Share statistics
 array:24 [
  "pii" => "S1579212918300831"
  "issn" => "15792129"
  "doi" => "10.1016/j.arbr.2017.10.023"
  "estado" => "S300"
  "fechaPublicacion" => "2018-05-01"
  "aid" => "1763"
  "copyright" => "SEPAR"
  "copyrightAnyo" => "2017"
  "documento" => "simple-article"
  "crossmark" => 1
  "subdocumento" => "cor"
  "cita" => "Arch Bronconeumol. 2018;54:297"
  "abierto" => array:3 [
    "ES" => false
    "ES2" => false
    "LATM" => false
  ]
  "gratuito" => false
  "lecturas" => array:2 [
    "total" => 998
    "formatos" => array:3 [
      "EPUB" => 131
      "HTML" => 578
      "PDF" => 289
    ]
  ]
  "Traduccion" => array:1 [
    "es" => array:19 [
      "pii" => "S030028961730409X"
      "issn" => "03002896"
      "doi" => "10.1016/j.arbres.2017.10.017"
      "estado" => "S300"
      "fechaPublicacion" => "2018-05-01"
      "aid" => "1763"
      "copyright" => "SEPAR"
      "documento" => "simple-article"
      "crossmark" => 1
      "subdocumento" => "cor"
      "cita" => "Arch Bronconeumol. 2018;54:297"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 1355
        "formatos" => array:3 [
          "EPUB" => 130
          "HTML" => 782
          "PDF" => 443
        ]
      ]
      "es" => array:10 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Carta al Director</span>"
        "titulo" => "Comentarios al tratamiento de la tuberculosis con resistencia"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "paginas" => array:1 [
          0 => array:1 [
            "paginaInicial" => "297"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Comments On The Treatment Of Resistant Tuberculosis"
          ]
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "Jos&#233; Francisco Pascual Pareja"
            "autores" => array:1 [
              0 => array:2 [
                "nombre" => "Jos&#233; Francisco"
                "apellidos" => "Pascual Pareja"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S1579212918300831"
          "doi" => "10.1016/j.arbr.2017.10.023"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => false
            "ES2" => false
            "LATM" => false
          ]
          "gratuito" => false
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212918300831?idApp=UINPBA00003Z"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S030028961730409X?idApp=UINPBA00003Z"
      "url" => "/03002896/0000005400000005/v1_201805020858/S030028961730409X/v1_201805020858/es/main.assets"
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S1579212918300892"
    "issn" => "15792129"
    "doi" => "10.1016/j.arbr.2018.03.001"
    "estado" => "S300"
    "fechaPublicacion" => "2018-05-01"
    "aid" => "1805"
    "copyright" => "SEPAR"
    "documento" => "simple-article"
    "crossmark" => 1
    "subdocumento" => "cor"
    "cita" => "Arch Bronconeumol. 2018;54:298"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 1077
      "formatos" => array:3 [
        "EPUB" => 154
        "HTML" => 599
        "PDF" => 324
      ]
    ]
    "en" => array:10 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>"
      "titulo" => "Comments on the SEPAR Guidelines for the Diagnosis and Treatment of Drug-Resistant Tuberculosis"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:1 [
          "paginaInicial" => "298"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Comentarios a la normativa SEPAR de diagn&#243;stico y tratamiento de la tuberculosis con resistencia a f&#225;rmacos"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Jos&#233; A&#46; Caminero, Joan A&#46; Cayl&#225;, Jos&#233;-Mar&#237;a Garc&#237;a-Garc&#237;a, Francisco J&#46; Garc&#237;a-P&#233;rez, Juan J&#46; Palacios, Juan Ruiz-Manzano"
          "autores" => array:6 [
            0 => array:2 [
              "nombre" => "Jos&#233; A&#46;"
              "apellidos" => "Caminero"
            ]
            1 => array:2 [
              "nombre" => "Joan A&#46;"
              "apellidos" => "Cayl&#225;"
            ]
            2 => array:2 [
              "nombre" => "Jos&#233;-Mar&#237;a"
              "apellidos" => "Garc&#237;a-Garc&#237;a"
            ]
            3 => array:2 [
              "nombre" => "Francisco J&#46;"
              "apellidos" => "Garc&#237;a-P&#233;rez"
            ]
            4 => array:2 [
              "nombre" => "Juan J&#46;"
              "apellidos" => "Palacios"
            ]
            5 => array:2 [
              "nombre" => "Juan"
              "apellidos" => "Ruiz-Manzano"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0300289618300139"
        "doi" => "10.1016/j.arbres.2017.12.015"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289618300139?idApp=UINPBA00003Z"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212918300892?idApp=UINPBA00003Z"
    "url" => "/15792129/0000005400000005/v1_201804290447/S1579212918300892/v1_201804290447/en/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S1579212918300880"
    "issn" => "15792129"
    "doi" => "10.1016/j.arbr.2017.09.019"
    "estado" => "S300"
    "fechaPublicacion" => "2018-05-01"
    "aid" => "1756"
    "copyright" => "SEPAR"
    "documento" => "simple-article"
    "crossmark" => 1
    "subdocumento" => "crp"
    "cita" => "Arch Bronconeumol. 2018;54:295-6"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 1163
      "formatos" => array:3 [
        "EPUB" => 127
        "HTML" => 725
        "PDF" => 311
      ]
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Scientific Letter</span>"
      "titulo" => "Pulmonary Lesions&#58; Cause or Consequence of Respiratory Infection&#63;"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "295"
          "paginaFinal" => "296"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Lesi&#243;n pulmonar&#58; &#191;causa o consecuencia de infecci&#243;n respiratoria&#63;"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Fig&#46; 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 1162
              "Ancho" => 2500
              "Tamanyo" => 237083
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">&#40;A&#41; PA chest X-ray&#58; unilocular air cyst in left lung base&#46; &#40;B&#41; Chest CT&#58; thin-walled air cavity in left lower lobe&#46; &#40;C&#41; PA chest X-ray&#58; increased density in right upper lobe of the lung&#46; No cystic lesion is observed&#46; &#40;D&#41; PA chest X-ray&#58; unilocular air cyst in right lung&#46; &#40;E&#41; PA chest X-ray&#58; increased density in right lung&#46; &#40;F&#41; Chest CT&#58; image of thin-walled unilocular cyst containing air&#44; located in the apical segment of the right lower lobe&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Javier Nogueira L&#243;pez, Laura D&#237;az Munilla, Natividad Viguria S&#225;nchez, Laura Moreno-Galarraga"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "Javier"
              "apellidos" => "Nogueira L&#243;pez"
            ]
            1 => array:2 [
              "nombre" => "Laura"
              "apellidos" => "D&#237;az Munilla"
            ]
            2 => array:2 [
              "nombre" => "Natividad"
              "apellidos" => "Viguria S&#225;nchez"
            ]
            3 => array:2 [
              "nombre" => "Laura"
              "apellidos" => "Moreno-Galarraga"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0300289617304027"
        "doi" => "10.1016/j.arbres.2017.09.017"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289617304027?idApp=UINPBA00003Z"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212918300880?idApp=UINPBA00003Z"
    "url" => "/15792129/0000005400000005/v1_201804290447/S1579212918300880/v1_201804290447/en/main.assets"
  ]
  "en" => array:13 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>"
    "titulo" => "Comments on the Treatment of Resistant Tuberculosis"
    "tieneTextoCompleto" => true
    "saludo" => "To the Editor&#44;"
    "paginas" => array:1 [
      0 => array:1 [
        "paginaInicial" => "297"
      ]
    ]
    "autores" => array:1 [
      0 => array:3 [
        "autoresLista" => "Jos&#233; Francisco Pascual Pareja"
        "autores" => array:1 [
          0 => array:3 [
            "nombre" => "Jos&#233; Francisco"
            "apellidos" => "Pascual Pareja"
            "email" => array:1 [
              0 => "josefrancisco&#46;pascual&#64;salud&#46;madrid&#46;org"
            ]
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:2 [
            "entidad" => "Servicio de Medicina Interna&#44; Unidad de Tuberculosis&#44; Complejo Hospitalario La Paz-Cantoblanco-Carlos III&#44; Madrid&#44; Spain"
            "identificador" => "aff0005"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Comentarios al tratamiento de la tuberculosis con resistencia"
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">I read with interest the guidelines published by Caminero et al&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a> on the diagnosis and treatment of drug-resistant tuberculosis&#46; I agree that according to the published evidence&#44; bedaquiline and delamanid should be considered essential components in the design of multidrug-resistant &#40;MDR&#41; tuberculosis treatment regimens&#44; as the authors set out in their rational classification and sequential use of anti-TB drugs for the design of a treatment regimen &#40;Caminero et al&#46;&#44; Table 3<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a>&#41;&#46; Indeed&#44; the 2016 WHO classification<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">2</span></a> should have included them in group C &#40;other core second-line drugs&#41; along with linezolid&#44; rather than in group D &#40;add-on agents&#44; not part of the core regimen&#41;&#46; Caminero et al&#46;&#44; however&#44; seem to give a greater theoretical than practical value to bedaquiline and delamanid&#44; as treatment regimens with these drugs are not recommended from the outset&#44; probably for the same reason that WHO included them in group D2&#58; these drugs are very costly&#46; Nevertheless&#44; it is important to bear in mind that some studies have shown that the inclusion of these expensive drugs in multi-resistant tuberculosis treatment is a cost-effective measure&#46;<a class="elsevierStyleCrossRefs" href="#bib0040"><span class="elsevierStyleSup">3&#44;4</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">These guidelines recommend that priority be given to the shorter 9&#8211;12 month regimen proposed by the WHO in 2016&#44; known as the &#8220;9-month Bangladesh regimen&#8221;&#44;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">2</span></a> for all patients with rifampicin or multiresistant tuberculosis who have not previously received fluoroquinolones &#40;FQ&#41; or second-line injectable drugs &#40;SLID&#41; or who can demonstrate sensitivity in vitro to these 2 classes of antibiotics&#46; The WHO also recommends that this regimen should not be used in patients with suspected or confirmed resistance to 1 or more drugs in a shorter regimen &#40;e&#46;g&#46;&#44; pyrazinamide&#41;&#44; apart from FQs and SLIDs&#46; Some studies have raised serious questions about the suitability of shorter regimens in certain regions of the world &#40;including some European countries&#41;&#44; due to the prevalent resistance patterns in those areas&#46;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">5</span></a> Moreover&#44; the shorter regimen should be avoided in patients with extrapulmonary disease and in pregnancy&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">2</span></a></p></span>"
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Pascual Pareja JF&#46; Comentarios al tratamiento de la tuberculosis con resistencia&#46; Arch Bronconeumol&#46; 2018&#59;54&#58;297&#46;</p>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0015"
          "bibliografiaReferencia" => array:5 [
            0 => array:3 [
              "identificador" => "bib0030"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Diagnosis and treatment of drug-resistant tuberculosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "J&#46;A&#46; Caminero"
                            1 => "J&#46;A&#46; Cayla"
                            2 => "J&#46;M&#46; Garc&#237;a-Garc&#237;a"
                            3 => "F&#46;J&#46; Garc&#237;a-P&#233;rez"
                            4 => "J&#46;J&#46; Palacios"
                            5 => "J&#46; Ruiz-Manzano"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.arbres.2017.02.006"
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Bronconeumol"
                        "fecha" => "2017"
                        "volumen" => "53"
                        "paginaInicial" => "501"
                        "paginaFinal" => "509"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/28359606"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "WHO treatment guidelines for drug-resistant tuberculosis&#46; 2016 update&#46; Available from&#58; <a id="intr0010" class="elsevierStyleInterRef" href="http://apps.who.int/iris/bitstream/10665/250125/1/9789241549639-eng.pdf?ua=1">http&#58;&#47;&#47;apps&#46;who&#46;int&#47;iris&#47;bitstream&#47;10665&#47;250125&#47;1&#47;9789241549639-eng&#46;pdf&#63;ua&#61;1</a> &#91;reviewed October 2016&#93;&#44; &#91;accessed 30&#46;09&#46;17&#93;&#46;"
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0040"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cost-effectiveness of adding novel or group 5 interventions to a background regimen for the treatment of multidrug-resistant tuberculosis in Germany"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "D&#46; Wirth"
                            1 => "R&#46; Dass"
                            2 => "R&#46; Hettle"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1186/s12913-017-2118-2"
                      "Revista" => array:5 [
                        "tituloSerie" => "BMC Health Serv Res"
                        "fecha" => "2017"
                        "volumen" => "17"
                        "paginaInicial" => "182"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/28270207"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0045"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cost-effectiveness of adding bedaquiline to drug regimens for the treatment of multidrug-resistant tuberculosis in the UK"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "L&#46;J&#46; Wolfson"
                            1 => "A&#46; Walker"
                            2 => "R&#46; Hettle"
                            3 => "X&#46; Lu"
                            4 => "C&#46; Kambili"
                            5 => "A&#46; Murungi"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1371/journal.pone.0120763"
                      "Revista" => array:5 [
                        "tituloSerie" => "PLOS ONE"
                        "fecha" => "2015"
                        "volumen" => "10"
                        "paginaInicial" => "e0120763"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25794045"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0050"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Limited benefit of the new shorter multidrug-resistant tuberculosis regimen in Europe"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "C&#46; Lange"
                            1 => "R&#46; Duarte"
                            2 => "M&#46; Fr&#233;chet-Jachym"
                            3 => "G&#46; Guenther"
                            4 => "L&#46; Guglielmetti"
                            5 => "I&#46;D&#46; Olaru"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1164/rccm.201606-1097LE"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Respir Crit Care Med"
                        "fecha" => "2016"
                        "volumen" => "194"
                        "paginaInicial" => "1029"
                        "paginaFinal" => "1031"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/27685538"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/15792129/0000005400000005/v1_201804290447/S1579212918300831/v1_201804290447/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "45358"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Letters to the Editor"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/15792129/0000005400000005/v1_201804290447/S1579212918300831/v1_201804290447/en/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212918300831?idApp=UINPBA00003Z"
]
Article information
ISSN: 15792129
Original language: English
The statistics are updated each day
Year/Month Html Pdf Total
2024 November 6 2 8
2024 October 44 14 58
2024 September 54 13 67
2024 August 74 34 108
2024 July 43 21 64
2024 June 54 29 83
2024 May 63 35 98
2024 April 46 24 70
2024 March 27 25 52
2024 February 41 21 62
2023 March 5 4 9
2023 February 29 18 47
2023 January 26 31 57
2022 December 39 40 79
2022 November 48 22 70
2022 October 46 39 85
2022 September 43 35 78
2022 August 32 43 75
2022 July 29 46 75
2022 June 29 38 67
2022 May 45 31 76
2022 April 35 31 66
2022 March 37 37 74
2022 February 46 22 68
2022 January 35 43 78
2021 December 35 44 79
2021 November 29 37 66
2021 October 30 44 74
2021 September 32 45 77
2021 August 15 34 49
2021 July 22 29 51
2021 June 35 41 76
2021 May 38 47 85
2021 April 84 115 199
2021 March 36 29 65
2021 February 21 18 39
2021 January 31 15 46
2020 December 21 14 35
2020 November 22 18 40
2020 October 27 21 48
2020 September 17 13 30
2020 August 20 14 34
2020 July 29 30 59
2020 June 26 2 28
2020 May 45 13 58
2020 March 13 7 20
2020 February 33 17 50
2020 January 46 14 60
2019 December 23 8 31
2019 November 31 19 50
2019 October 37 18 55
2019 September 33 5 38
2019 August 30 22 52
2019 July 16 23 39
2019 June 37 7 44
2019 May 41 21 62
2019 April 38 28 66
2019 March 42 29 71
2019 February 29 20 49
2019 January 37 18 55
2018 December 42 21 63
2018 November 65 27 92
2018 October 9 1 10
Show all

Follow this link to access the full text of the article

Archivos de Bronconeumología

Are you a health professional able to prescribe or dispense drugs?