array:24 [
  "pii" => "S1579212917301751"
  "issn" => "15792129"
  "doi" => "10.1016/j.arbr.2017.05.006"
  "estado" => "S300"
  "fechaPublicacion" => "2017-07-01"
  "aid" => "1521"
  "copyright" => "SEPAR"
  "copyrightAnyo" => "2016"
  "documento" => "article"
  "crossmark" => 1
  "subdocumento" => "fla"
  "cita" => "Arch Bronconeumol. 2017;53:375-80"
  "abierto" => array:3 [
    "ES" => false
    "ES2" => false
    "LATM" => false
  ]
  "gratuito" => false
  "lecturas" => array:2 [
    "total" => 1342
    "formatos" => array:3 [
      "EPUB" => 133
      "HTML" => 777
      "PDF" => 432
    ]
  ]
  "Traduccion" => array:1 [
    "es" => array:19 [
      "pii" => "S0300289616303519"
      "issn" => "03002896"
      "doi" => "10.1016/j.arbres.2016.11.020"
      "estado" => "S300"
      "fechaPublicacion" => "2017-07-01"
      "aid" => "1521"
      "copyright" => "SEPAR"
      "documento" => "article"
      "crossmark" => 1
      "subdocumento" => "fla"
      "cita" => "Arch Bronconeumol. 2017;53:375-80"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 4023
        "formatos" => array:3 [
          "EPUB" => 138
          "HTML" => 3295
          "PDF" => 590
        ]
      ]
      "es" => array:13 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Original</span>"
        "titulo" => "Asociaci&#243;n de la masa muscular determinada mediante DEXA con los resultados espirom&#233;tricos de individuos sanos"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "tieneResumen" => array:2 [
          0 => "es"
          1 => "en"
        ]
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "375"
            "paginaFinal" => "380"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Relationship of Muscle Mass Determined by DEXA with Spirometric Results in Healthy Individuals"
          ]
        ]
        "contieneResumen" => array:2 [
          "es" => true
          "en" => true
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "resumenGrafico" => array:2 [
          "original" => 0
          "multimedia" => array:7 [
            "identificador" => "fig0005"
            "etiqueta" => "Figura 1"
            "tipo" => "MULTIMEDIAFIGURA"
            "mostrarFloat" => true
            "mostrarDisplay" => false
            "figura" => array:1 [
              0 => array:4 [
                "imagen" => "gr1.jpeg"
                "Alto" => 1152
                "Ancho" => 1578
                "Tamanyo" => 113868
              ]
            ]
            "descripcion" => array:1 [
              "es" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">An&#225;lisis de componentes principales en varones con un 76&#44;07&#37; de explicaci&#243;n global &#40;47&#44;1&#37; que explica la primera componente y 28&#44;97&#37; la segunda&#41;&#46;</p> <p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">FEV<span class="elsevierStyleInf">1</span>&#58; volumen espiratorio forzado en el primer segundo&#59; FVC&#58; capacidad vital forzada&#59; IMC&#58; &#237;ndice de masa corporal&#59; PEF&#58; pico flujo espiratorio&#59; TNGP&#58; tejido magro de las extremidades inferiores&#59; TNGT&#58; tejido magro total&#59; TNGTR&#58; tejido magro del tronco&#46;</p>"
            ]
          ]
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "Rafael Mart&#237;n Holguera, Ana Isabel Turri&#243;n Nieves, Rosa Rodr&#237;guez Torres, Mar&#237;a Concepci&#243;n Alonso"
            "autores" => array:4 [
              0 => array:2 [
                "nombre" => "Rafael"
                "apellidos" => "Mart&#237;n Holguera"
              ]
              1 => array:2 [
                "nombre" => "Ana Isabel"
                "apellidos" => "Turri&#243;n Nieves"
              ]
              2 => array:2 [
                "nombre" => "Rosa"
                "apellidos" => "Rodr&#237;guez Torres"
              ]
              3 => array:2 [
                "nombre" => "Mar&#237;a Concepci&#243;n"
                "apellidos" => "Alonso"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S1579212917301751"
          "doi" => "10.1016/j.arbr.2017.05.006"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => false
            "ES2" => false
            "LATM" => false
          ]
          "gratuito" => false
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212917301751?idApp=UINPBA00003Z"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289616303519?idApp=UINPBA00003Z"
      "url" => "/03002896/0000005300000007/v2_201706291228/S0300289616303519/v2_201706291228/es/main.assets"
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S1579212916302683"
    "issn" => "15792129"
    "doi" => "10.1016/j.arbr.2016.11.006"
    "estado" => "S300"
    "fechaPublicacion" => "2017-07-01"
    "aid" => "1472"
    "copyright" => "SEPAR"
    "documento" => "article"
    "crossmark" => 1
    "subdocumento" => "fla"
    "cita" => "Arch Bronconeumol. 2017;53:381-6"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 2358
      "formatos" => array:3 [
        "EPUB" => 142
        "HTML" => 1547
        "PDF" => 669
      ]
    ]
    "en" => array:12 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Original Article</span>"
      "titulo" => "Association of Gene Polymorphisms in Interleukin 6 in Infantile Bronchial Asthma"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "381"
          "paginaFinal" => "386"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Asociaci&#243;n entre polimorfismos gen&#233;ticos de la interleucina 6 y el asma bronquial en ni&#241;os"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Eva Babusikova, Jana Jurecekova, Milos Jesenak, Andrea Evinova"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "Eva"
              "apellidos" => "Babusikova"
            ]
            1 => array:2 [
              "nombre" => "Jana"
              "apellidos" => "Jurecekova"
            ]
            2 => array:2 [
              "nombre" => "Milos"
              "apellidos" => "Jesenak"
            ]
            3 => array:2 [
              "nombre" => "Andrea"
              "apellidos" => "Evinova"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0300289616302551"
        "doi" => "10.1016/j.arbres.2016.09.012"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289616302551?idApp=UINPBA00003Z"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212916302683?idApp=UINPBA00003Z"
    "url" => "/15792129/0000005300000007/v1_201706290145/S1579212916302683/v1_201706290145/en/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S157921291730174X"
    "issn" => "15792129"
    "doi" => "10.1016/j.arbr.2017.05.005"
    "estado" => "S300"
    "fechaPublicacion" => "2017-07-01"
    "aid" => "1522"
    "copyright" => "SEPAR"
    "documento" => "article"
    "crossmark" => 1
    "subdocumento" => "fla"
    "cita" => "Arch Bronconeumol. 2017;53:366-74"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 4056
      "formatos" => array:3 [
        "EPUB" => 175
        "HTML" => 3213
        "PDF" => 668
      ]
    ]
    "en" => array:13 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Original article</span>"
      "titulo" => "Etiology of Bronchiectasis in a Cohort of 2047 Patients&#46; An Analysis of the Spanish Historical Bronchiectasis Registry"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "366"
          "paginaFinal" => "374"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Etiolog&#237;a de las bronquiectasias en una cohorte de 2&#46;047 pacientes&#46; An&#225;lisis del registro hist&#243;rico espa&#241;ol"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Fig&#46; 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 1971
              "Ancho" => 1628
              "Tamanyo" => 173686
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Flow chart&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Casilda Olveira, Alicia Padilla, Miguel-&#193;ngel Mart&#237;nez-Garc&#237;a, David de la Rosa, Rosa-Mar&#237;a Gir&#243;n, Montserrat Vendrell, Luis M&#225;iz, Luis Border&#237;as, Eva Polverino, Eva Mart&#237;nez-Morag&#243;n, Olga Rajas, Francisco Casas, Rosa Cordovilla, Javier de Gracia"
          "autores" => array:14 [
            0 => array:2 [
              "nombre" => "Casilda"
              "apellidos" => "Olveira"
            ]
            1 => array:2 [
              "nombre" => "Alicia"
              "apellidos" => "Padilla"
            ]
            2 => array:2 [
              "nombre" => "Miguel-&#193;ngel"
              "apellidos" => "Mart&#237;nez-Garc&#237;a"
            ]
            3 => array:2 [
              "nombre" => "David"
              "apellidos" => "de la Rosa"
            ]
            4 => array:2 [
              "nombre" => "Rosa-Mar&#237;a"
              "apellidos" => "Gir&#243;n"
            ]
            5 => array:2 [
              "nombre" => "Montserrat"
              "apellidos" => "Vendrell"
            ]
            6 => array:2 [
              "nombre" => "Luis"
              "apellidos" => "M&#225;iz"
            ]
            7 => array:2 [
              "nombre" => "Luis"
              "apellidos" => "Border&#237;as"
            ]
            8 => array:2 [
              "nombre" => "Eva"
              "apellidos" => "Polverino"
            ]
            9 => array:2 [
              "nombre" => "Eva"
              "apellidos" => "Mart&#237;nez-Morag&#243;n"
            ]
            10 => array:2 [
              "nombre" => "Olga"
              "apellidos" => "Rajas"
            ]
            11 => array:2 [
              "nombre" => "Francisco"
              "apellidos" => "Casas"
            ]
            12 => array:2 [
              "nombre" => "Rosa"
              "apellidos" => "Cordovilla"
            ]
            13 => array:2 [
              "nombre" => "Javier"
              "apellidos" => "de Gracia"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0300289616303520"
        "doi" => "10.1016/j.arbres.2016.12.003"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289616303520?idApp=UINPBA00003Z"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S157921291730174X?idApp=UINPBA00003Z"
    "url" => "/15792129/0000005300000007/v1_201706290145/S157921291730174X/v1_201706290145/en/main.assets"
  ]
  "en" => array:20 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Original article</span>"
    "titulo" => "Relationship of Muscle Mass Determined by DEXA with Spirometric Results in Healthy Individuals"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "375"
        "paginaFinal" => "380"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "Rafael Mart&#237;n Holguera, Ana Isabel Turri&#243;n Nieves, Rosa Rodr&#237;guez Torres, Mar&#237;a Concepci&#243;n Alonso"
        "autores" => array:4 [
          0 => array:4 [
            "nombre" => "Rafael"
            "apellidos" => "Mart&#237;n Holguera"
            "email" => array:1 [
              0 => "rafael&#46;martin&#64;uah&#46;es"
            ]
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "Ana Isabel"
            "apellidos" => "Turri&#243;n Nieves"
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "Rosa"
            "apellidos" => "Rodr&#237;guez Torres"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "Mar&#237;a Concepci&#243;n"
            "apellidos" => "Alonso"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">c</span>"
                "identificador" => "aff0015"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:3 [
          0 => array:3 [
            "entidad" => "Departamento de Cirug&#237;a y Ciencias M&#233;dico Sociales&#44; Unidad Docente de Anatom&#237;a y Embriolog&#237;a Humanas&#44; Facultad de Medicina&#44; Universidad de Alcal&#225; de Henares&#44; Alcal&#225; de Henares&#44; Madrid&#44; Spain"
            "etiqueta" => "a"
            "identificador" => "aff0005"
          ]
          1 => array:3 [
            "entidad" => "Departamento de Medicina Interna&#44; Servicio de ESI-Reumatolog&#237;a&#44; Hospital Universitario Pr&#237;ncipe de Asturias&#44; Alcal&#225; de Henares&#44; Madrid&#44; Spain"
            "etiqueta" => "b"
            "identificador" => "aff0010"
          ]
          2 => array:3 [
            "entidad" => "Departamento de F&#237;sica y Matem&#225;ticas&#44; Unidad docente de Matem&#225;ticas&#44; Edificio Polit&#233;cnico&#44; Universidad de Alcal&#225; de Henares&#44; Alcal&#225; de Henares&#44; Madrid&#44; Spain"
            "etiqueta" => "c"
            "identificador" => "aff0015"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Asociaci&#243;n de la masa muscular determinada mediante DEXA con los resultados espirom&#233;tricos de individuos sanos"
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:7 [
        "identificador" => "fig0010"
        "etiqueta" => "Fig&#46; 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 1115
            "Ancho" => 1582
            "Tamanyo" => 120215
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Principal component analysis in women with an overall explanation of 73&#46;03&#37; &#40;46&#46;97&#37; explains the first component and 26&#46;05&#37; the second&#41;&#46; FEV<span class="elsevierStyleInf">1</span>&#58; Forced expiratory volume in 1<span class="elsevierStyleHsp" style=""></span>s&#59; FVC&#58; forced vital capacity&#59; BMI&#58; body mass index&#59; PEF&#58; peak expiratory flow&#59; LLM&#58; leg lean mass&#59; TLM&#58; total lean body mass&#59; TrLM&#58; trunk lean mass&#46;</p>"
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0065">Introduction</span><p id="par0005" class="elsevierStylePara elsevierViewall">Forced spirometry is the principal test for evaluating lung function in individuals&#46; The main factors determining spirometric results are sex&#44; age&#44; height&#44; and weight&#44; and these variables are used to produce equations predicting normal reference values&#46; Several authors<a class="elsevierStyleCrossRefs" href="#bib0150"><span class="elsevierStyleSup">1&#44;2</span></a> believe that there must be other factors that determine spirometry results&#44; which would explain the variability in test values obtained in healthy individuals with similar characteristics&#46; The premise of this study is that one of the factors that might cause this variability could be muscle mass&#46; Although some previous studies<a class="elsevierStyleCrossRefs" href="#bib0160"><span class="elsevierStyleSup">3&#8211;6</span></a> have already evaluated this possibility&#44; we believe that the influence of an individual&#39;s muscle mass on spirometric results has not been clearly established&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">The technique of choice for evaluating muscle mass is dual energy X-ray absorptiometry &#40;DEXA&#41;&#46; This is an imaging technique used to quantify lean body mass &#40;fat-free mass&#41; in both the whole body and in different body regions&#46; Lean body mass is an estimation of muscle mass&#46; This test offers reliable measurements that are comparable over time&#46; It is&#44; moreover&#44; a technique widely used in respiratory clinics&#44;<a class="elsevierStyleCrossRefs" href="#bib0180"><span class="elsevierStyleSup">7&#8211;9</span></a> mainly for assessing muscle mass in patients with chronic obstructive pulmonary disease &#40;COPD&#41;&#44; who often present muscle dysfunction of the ventilatory system and the lower limbs&#46;<a class="elsevierStyleCrossRefs" href="#bib0195"><span class="elsevierStyleSup">10&#44;11</span></a> Muscle training improves exercise tolerance&#44; muscle strength&#44; dyspnea&#44; fatigue&#44; and quality of life in these patients&#46; The impact of muscle mass on the symptoms and prognosis of asthmatics has also been studied&#46;<a class="elsevierStyleCrossRefs" href="#bib0205"><span class="elsevierStyleSup">12&#44;13</span></a> Increasing numbers of studies are using DEXA to evaluate the outcome of muscle training in respiratory rehabilitation programs in COPD patients and to determine their prognosis&#46;<a class="elsevierStyleCrossRefs" href="#bib0215"><span class="elsevierStyleSup">14&#8211;17</span></a> For this reason&#44; we identified a need to establish the association between spirometric values and muscle mass parameters determined by DEXA in healthy individuals&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">The aim of this study was to quantify the association between spirometric variables and muscle mass estimated by DEXA&#44; to establish whether muscle mass is an important determinant in the spirometric results of healthy individuals&#44; and to help establish the normality of this association&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0070">Methods</span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">Study Subjects</span><p id="par0025" class="elsevierStylePara elsevierViewall">The study population consisted of 305 healthy subjects of Caucasian origin &#40;144 men and 161 women&#41;&#44; aged between 18 and 77 years&#44; inclusive&#46; Participation in the study was voluntary&#44; and all subjects were recruited from an urban setting in the environs of the Universidad de Alcal&#225; de Henares&#46; Subjects were matched in terms of lifestyle and diet&#44; and had performed physical exercise sporadically throughout their lives&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">Study inclusion criteria were&#58;<ul class="elsevierStyleList" id="lis0005"><li class="elsevierStyleListItem" id="lsti0005"><span class="elsevierStyleLabel">-</span><p id="par0035" class="elsevierStylePara elsevierViewall">Never-smoker&#46;</p></li><li class="elsevierStyleListItem" id="lsti0010"><span class="elsevierStyleLabel">-</span><p id="par0040" class="elsevierStylePara elsevierViewall">No metabolic diseases or pharmacological treatments that might alter metabolism&#46;</p></li><li class="elsevierStyleListItem" id="lsti0015"><span class="elsevierStyleLabel">-</span><p id="par0045" class="elsevierStylePara elsevierViewall">No muscle or neuromuscular diseases&#46;</p></li><li class="elsevierStyleListItem" id="lsti0020"><span class="elsevierStyleLabel">-</span><p id="par0050" class="elsevierStylePara elsevierViewall">No thoracic abnormalities&#44; determined as a thoracic index within the mean for their age&#44; plus or minus 2 standard deviations&#46;</p></li><li class="elsevierStyleListItem" id="lsti0025"><span class="elsevierStyleLabel">-</span><p id="par0055" class="elsevierStylePara elsevierViewall">No obvious changes in the physiological curvature of the spine&#46;</p></li><li class="elsevierStyleListItem" id="lsti0030"><span class="elsevierStyleLabel">-</span><p id="par0060" class="elsevierStylePara elsevierViewall">No neoplasms&#44; cardiovascular diseases&#44; chronic bronchial diseases&#44; or episodes of spontaneous pneumothorax&#46;</p></li></ul></p><p id="par0065" class="elsevierStylePara elsevierViewall">All individuals had spirometric results within normal limits &#40;forced vital capacity &#91;FVC&#93; and forced expiratory volume in 1<span class="elsevierStyleHsp" style=""></span>s &#91;FEV<span class="elsevierStyleInf">1</span>&#93; over 80&#37; predicted&#44; and FEV<span class="elsevierStyleInf">1</span>&#47;FVC greater than 70&#37; and less than 80&#37;&#41;&#44; and agreed voluntarily to undergo the specific study tests&#44; after giving informed consent&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0080">Methods</span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0085">Muscle Mass Assessment</span><p id="par0070" class="elsevierStylePara elsevierViewall">To quantify muscle mass in each individual&#44; a whole-body dual energy X-ray absorptiometry &#40;DEXA&#41; was performed&#44; from which overall and regional lean body mass &#40;fat-free soft tissue mass&#41; values were obtained&#44; providing an estimation of muscle mass&#46;</p><p id="par0075" class="elsevierStylePara elsevierViewall">This technique uses a highly stable X-ray generator to produce a spectrum of broad energy band levels&#46; The apparatus consists of NaI crystal scintillation detectors placed in tandem&#46; The source of radiation and the detectors are placed opposite each other and mechanically connected so that they move simultaneously&#46; The light beam passes in a posteroanterior direction through the tissue while the patient lies perfectly still in a supine position&#46; Energy is absorbed depending on the density of the tissue that it passes through&#58; absorption is zero in air&#44; small in fat&#44; greater in soft tissues&#44; and very significant in bone&#46; Photons that have not been absorbed are captured by the detector&#44; so the density of the area explored is proportional to the attenuation of radiation by the tissue&#46;</p><p id="par0080" class="elsevierStylePara elsevierViewall">This is a safe technique&#44; since the dose of radiation used is minimal&#44; and very little inter and intra-observer variation has been demonstrated&#44; making it very useful for research&#46;</p><p id="par0085" class="elsevierStylePara elsevierViewall">In our study&#44; we quantified&#44; in grams&#58;<ul class="elsevierStyleList" id="lis0010"><li class="elsevierStyleListItem" id="lsti0035"><span class="elsevierStyleLabel">-</span><p id="par0090" class="elsevierStylePara elsevierViewall">Total lean mass &#40;TLM&#41;&#46;</p></li><li class="elsevierStyleListItem" id="lsti0040"><span class="elsevierStyleLabel">-</span><p id="par0095" class="elsevierStylePara elsevierViewall">Trunk lean mass &#40;TrLM&#41;&#46;</p></li><li class="elsevierStyleListItem" id="lsti0045"><span class="elsevierStyleLabel">-</span><p id="par0100" class="elsevierStylePara elsevierViewall">Leg lean mass &#40;LLM&#41;&#46;</p></li></ul></p><p id="par0105" class="elsevierStylePara elsevierViewall">The examination was performed using the Norland densitometer XR-800 TM WITH Illuminatus software version 4&#46;5&#46;0 &#40;Norland&#44; a CooperSurgical Company&#44; Fort Atkinson&#44; WI&#44; U&#46;S&#46;&#41;&#46; All densitometries were performed following standardized protocols provided by the manufacturer and described by Aguado et al&#46;<a class="elsevierStyleCrossRef" href="#bib0235"><span class="elsevierStyleSup">18</span></a></p><p id="par0110" class="elsevierStylePara elsevierViewall">All examinations were performed using the same equipment&#44; in the same laboratory by the same technician&#46;</p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0090">Evaluation of Lung Function</span><p id="par0115" class="elsevierStylePara elsevierViewall">All subjects underwent forced spirometry with a COSMED K4 b<span class="elsevierStyleSup">2</span> turbine spirometer&#44; after calibration of the flow measured using a calibration syringe certified by the <span class="elsevierStyleItalic">American Thoracic Society</span> &#40;ATS&#41;&#46; The spirometry study was performed according to the protocol recommended by the Spanish Society of Pulmonology and Thoracic Surgery &#40;SEPAR&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib0240"><span class="elsevierStyleSup">19</span></a> Absolute FVC and FEV<span class="elsevierStyleInf">1</span> values were measured in milliliters &#40;ml&#41;&#44; and peak expiratory flow &#40;PEF&#41; and forced expiratory flow between 25&#37; and 75&#37; of forced vital capacity &#40;FEF<span class="elsevierStyleInf">25&#37;&#8211;75&#37;</span>&#41; were measured in liters per second&#46;</p><p id="par0120" class="elsevierStylePara elsevierViewall">All tests were performed by the same technician&#44; in the same laboratory&#44; using the same equipment&#46;</p></span></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0095">Analysis</span><p id="par0125" class="elsevierStylePara elsevierViewall">The statistical analysis was performed using the SPSS 22&#46;0 and Statgraphics Centurion 17 package for Windows&#46;</p><p id="par0130" class="elsevierStylePara elsevierViewall">The arithmetic mean&#44; standard deviation&#44; and minimum and maximum values were obtained for men and women&#46; Differences in means of both sexes were evaluated using the t test for independent samples&#46;</p><p id="par0135" class="elsevierStylePara elsevierViewall">To explore linear associations between the spirometric variables and the lean mass variables&#44; principal components analysis on the correlation matrix was used to reduce dimensionality&#44; obtaining a 2-dimensional graphic that revealed the relationships between the variables&#44; so that the more acute the angle formed&#44; the greater the linear relationship&#46;</p><p id="par0140" class="elsevierStylePara elsevierViewall">Relationships between the different spirometric variables and the lean mass variables were analyzed using correlations&#46; Partial correlations were used&#44; adjusting for age and body mass index &#40;BMI&#41;&#44; to eliminate the possible effect of confounding factors &#40;age&#44; height and weight&#41;&#46;</p><p id="par0145" class="elsevierStylePara elsevierViewall">A multiple linear regression analysis was performed to determine if the lean mass variables could be considered as predictive factor for spirometric variables&#46;</p></span></span><span id="sec0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0100">Results</span><p id="par0150" class="elsevierStylePara elsevierViewall">Descriptive statistics of the muscle mass and lung function variables in men and women are shown in <a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a>&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><p id="par0155" class="elsevierStylePara elsevierViewall">All variables analyzed showed significant differences in mean values of both sexes&#44; except age and sex&#46; Means were higher in men&#44; as shown in <a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a>&#44; with statistically significant <span class="elsevierStyleItalic">p</span> values&#46;</p><p id="par0160" class="elsevierStylePara elsevierViewall">In the principal components analysis&#44; positive correlations between all spirometric variables and all lean mass variables were found in both sexes&#44; with the greatest correlation being observed for LLM &#40;<a class="elsevierStyleCrossRefs" href="#fig0005">Figs&#46; 1 and 2</a>&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0165" class="elsevierStylePara elsevierViewall">Partial correlations between lean mass and spirometric variables&#44; adjusting for age and BMI&#44; were positive and highly statistically significant in both women and men&#44; with higher coefficients in the latter &#40;<a class="elsevierStyleCrossRefs" href="#tbl0010">Tables 2 and 3</a>&#41;&#46;</p><elsevierMultimedia ident="tbl0010"></elsevierMultimedia><elsevierMultimedia ident="tbl0015"></elsevierMultimedia><p id="par0170" class="elsevierStylePara elsevierViewall">Variables showing higher correlation coefficients with FVC and with FEV<span class="elsevierStyleInf">1</span> were LLM in men and TrLM in women&#46;</p><p id="par0175" class="elsevierStylePara elsevierViewall">In the multiple linear regression analysis&#44; equations to predict spirometric variables according to age&#44; BMI and lean mass variables were obtained&#44; along with adjusted coefficients of determination &#40;<span class="elsevierStyleItalic">R</span><span class="elsevierStyleSup">2</span>&#41; &#40;<a class="elsevierStyleCrossRef" href="#tbl0020">Table 4</a>&#41;&#46;</p><elsevierMultimedia ident="tbl0020"></elsevierMultimedia><p id="par0180" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleItalic">R</span><span class="elsevierStyleSup">2</span> between lean mass and spirometric variables are greater in men&#46; The spirometric variable with the highest values was FEV<span class="elsevierStyleInf">1</span>&#44; followed by FVC and PEF&#44; in both men and women&#46; In men&#44; LLM is the variable that showed the highest <span class="elsevierStyleItalic">R</span><span class="elsevierStyleSup">2</span> with spirometric variables&#44; while in women&#44; it was TrLM&#46;</p><p id="par0185" class="elsevierStylePara elsevierViewall">All estimated regression coefficients in lean mass were positive and statistically significant &#40;<span class="elsevierStyleItalic">p</span>&#60;0&#46;05&#41;&#44; suggesting that the greater the amount of lean body mass&#44; the greater the absolute values obtained on spirometry&#46; The highest coefficients were for LLM in men and TrLM in women&#46;</p></span><span id="sec0045" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0105">Discussion and Conclusions</span><p id="par0190" class="elsevierStylePara elsevierViewall">The aim of this study was to establish the association between spirometric results and lean mass determined by DEXA in healthy individuals&#46; Variability in the spirometry values obtained in healthy individuals of similar characteristics have led some authors<a class="elsevierStyleCrossRefs" href="#bib0150"><span class="elsevierStyleSup">1&#44;2</span></a> to believe that factors other than sex&#44; age&#44; height&#44; and weight might determine results&#46; Determinants such as inherited genetic factors and the presence of certain vitamins in an individual&#39;s diet have been discussed&#46; The premise of this study is that one of the factors that might cause this variability could be muscle mass&#46; Other studies have attempted to establish the influence of the muscle component of the body on spirometric results in healthy individuals&#58;</p><p id="par0195" class="elsevierStylePara elsevierViewall">Cotes et al&#46;<a class="elsevierStyleCrossRef" href="#bib0160"><span class="elsevierStyleSup">3</span></a> found a significant association between the Fat-Free Mass Index &#40;FFMI&#41;&#44; in which lean mass is adjusted for subject height obtained from anthropometric measurements&#44; and the main spirometric parameters&#46; They used linear regression models to obtain reference equations that included FFMI&#44; and found that these equations were more accurate than those which included only sex&#44; age&#44; height&#44; and weight&#46;</p><p id="par0200" class="elsevierStylePara elsevierViewall">Mohamed et al&#46;<a class="elsevierStyleCrossRef" href="#bib0165"><span class="elsevierStyleSup">4</span></a> also measured a muscle mass parameter&#44; bone-free lean body mass &#40;BF-LBM&#41;&#44; using DEXA&#44; and&#44; like us&#44; found a significant positive association between that parameter and the main spirometric variables in a group of healthy Italian subjects&#46; The age range is similar&#44; but the series size is rather smaller than ours &#40;58 men and 60 women&#41;&#44; and the influence of regional lean mass variables was not studied&#46;</p><p id="par0205" class="elsevierStylePara elsevierViewall">More recently&#44; Lim et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib0170"><span class="elsevierStyleSup">5</span></a> in a study of elderly Korean individuals with no chronic respiratory diseases&#44; found a significant association between trunk and leg muscle measured by DEXA and the main spirometric parameters&#44; in both women and men&#46; Their results are similar to our findings&#44; although only elderly subjects of non-Caucasian origin were included&#46;</p><p id="par0215" class="elsevierStylePara elsevierViewall">Park et al&#46;<a class="elsevierStyleCrossRef" href="#bib0175"><span class="elsevierStyleSup">6</span></a> also conducted a study in Korean subjects&#44; but with a mean age of 46 years&#46; They found a significant correlation between lean body mass &#8211; measured in this case by bioelectric impedance &#8211; and spirometric parameters&#44; in both men and women&#46; However&#44; they did not obtain a sufficiently high <span class="elsevierStyleItalic">R</span><span class="elsevierStyleSup">2</span> to conclude that muscle mass was a factor that influenced breathing in the study individuals&#46;</p><p id="par0220" class="elsevierStylePara elsevierViewall">Mean values of all respiratory parameters are significantly higher among men than women&#46; The larger amount of total lean body mass in men might explain the difference in the spirometric results between both sexes&#44; taking into account that respiratory mechanical properties are basically the same in both&#46;<a class="elsevierStyleCrossRef" href="#bib0245"><span class="elsevierStyleSup">20</span></a> Mean amounts of lean body mass in the different body regions are also higher in men&#46; These results are in line with those of Aguado et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib0250"><span class="elsevierStyleSup">21</span></a> who determined total and regional lean mass by DEXA in a series of healthy individuals of both sexes&#44; grouped according to age&#46; These authors found consistently larger amounts of total and regional lean body mass in men&#46;</p><p id="par0225" class="elsevierStylePara elsevierViewall">One of the principal results of the study is the significant association of lean mass in the legs with the main spirometric parameters&#46; In men&#44; leg lean mass affected spirometric results even more than total lean mass or trunk lean mass&#44; where the major ventilatory muscles are located&#46; In the clinical setting&#44; Hillman et al&#46;<a class="elsevierStyleCrossRef" href="#bib0255"><span class="elsevierStyleSup">22</span></a> believe that muscle strength and muscle mass in the legs are a possible determinant of the efficacy of training programs for pulmonary rehabilitation&#46; They also observed that approximately 33&#37; of patients with COPD presented muscle dysfunction in the lower limbs&#44; even in the early stages of the disease&#46;</p><p id="par0230" class="elsevierStylePara elsevierViewall">While leg lean mass in women is also significantly associated with spirometric parameters&#44; this is not the variable that shows the greatest association&#46; Rather&#44; the amount of muscle mass in the trunk has most impact on spirometric results&#46; This difference between the sexes does not appear to be explained by differences in the regional distribution of lean mass&#44; since no significant differences in this distribution were revealed in the study&#46; In both sexes&#44; the amount of lean mass is greater in the trunk than in the legs&#44; and in similar proportions&#46; The explanation for this difference might be the predominantly thoracic breathing pattern in women&#46;</p><p id="par0235" class="elsevierStylePara elsevierViewall">The possible direct relationship between muscle mass and strength may explain the association between lean mass parameters and spirometric values&#46; This hypothesis is also supported by the fact that a significant association is also found between PEF values&#44; the spirometric parameter most dependent on expiratory muscle strength&#44; and lean mass values&#44; in both men and women&#46; In women&#44; PEF is most associated with trunk mean mass&#46; However&#44; some authors<a class="elsevierStyleCrossRefs" href="#bib0260"><span class="elsevierStyleSup">23&#44;24</span></a> found that strength does not depend exclusively on muscle mass&#44; and the relationship between these parameters is not linear&#46; The most widely used functional tests for measuring respiratory muscle strength are maximum inspiratory pressure &#40;MIP&#41; and maximum expiratory pressure &#40;MEP&#41;&#46; A further study&#44; evaluating the association between lean mass determined by DEXA and MIP and MEP values would help clarify this issue&#46; In this respect&#44; Costes et al&#46;<a class="elsevierStyleCrossRef" href="#bib0270"><span class="elsevierStyleSup">25</span></a> found in a study of elderly individuals of both sexes that trunk lean mass determined by DEXA predicts MIP values&#44; but only in women&#46; Hillman et al&#46;<a class="elsevierStyleCrossRef" href="#bib0255"><span class="elsevierStyleSup">22</span></a> also found an association between lean mass in the legs and muscle strength determined by dynamometry in COPD patients&#46;</p><p id="par0240" class="elsevierStylePara elsevierViewall">Another result from our study is that all lean mass variables have more effect on FEV<span class="elsevierStyleInf">1</span> than on the other spirometric parameters&#44; in both men and women&#46; The greater capacity of the expiratory muscles to generate strength may lead to a greater volume of air being expired in the first second of the forced spirometry maneuver&#46; A positive association is also seen between the amount of lean mass and FEF<span class="elsevierStyleInf">25&#37;&#8211;75&#37;</span>&#44; altered values of which suggest small airway obstruction&#44; and may point to the presence of early-stage obstructive disease&#46; This might mean that a lower mean muscle mass might be a factor in the appearance of obstructive spirometric patterns&#46; In this respect&#44; Minas et al&#46;<a class="elsevierStyleCrossRef" href="#bib0210"><span class="elsevierStyleSup">13</span></a> compared muscle mass measured by bioelectric impedance in smokers without COPD and in patients with COPD&#44; and found it to be significantly lower in the latter&#44; even in patients in mild stages of the disease&#46; The same authors studied a group of patients with asthma&#44; another of the most prevalent obstructive diseases&#46; They found that patients with severe treatment-resistant asthma had lower muscle mass measured by bioelectric impedance than those with milder forms of asthma&#44; suggesting that muscle mass may be used as a prognostic factor in these patients&#46;</p><p id="par0245" class="elsevierStylePara elsevierViewall">Another publication reports that up to one third of COPD patients had deteriorated muscle function in the lower limbs&#44; even in the early stages of the disease&#46;<a class="elsevierStyleCrossRef" href="#bib0275"><span class="elsevierStyleSup">26</span></a> However&#44; in our study&#44; we did not find a significant association between lean mass parameters and FEV<span class="elsevierStyleInf">1</span>&#47;FVC index in either sex&#46; We did not find&#44; then&#44; that lower lean mass was a factor for a lower FEV<span class="elsevierStyleInf">1</span>&#47;FVC index&#44; which would belie the idea that lower muscle mass might be associated with a greater tendency to develop obstructive spirometric patterns&#46;</p><p id="par0250" class="elsevierStylePara elsevierViewall">Spirometric values in healthy individuals are known to peak in the third decade of life&#44; in both men and women&#46; These values then gradually decline with age&#46;<a class="elsevierStyleCrossRef" href="#bib0280"><span class="elsevierStyleSup">27</span></a> The course of muscle mass is similar&#58; after reaching a peak&#44; it too declines progressively over the years&#46;<a class="elsevierStyleCrossRefs" href="#bib0285"><span class="elsevierStyleSup">28&#44;29</span></a> The association between lean mass and spirometric parameters might suggest that loss of muscle mass is one of the factors that might explain the age-related progressive decline in spirometric parameters&#44; as well as deterioration of the mechanical properties of the ribcage and loss of elasticity and distensibility of the alveoli and the airway&#46;</p><p id="par0255" class="elsevierStylePara elsevierViewall">In conclusion&#44; muscle mass has a significant influence on lung function in health individuals of both sexes&#44; but this influence is greater in men&#46;</p><p id="par0260" class="elsevierStylePara elsevierViewall">The amount of lean mass in the legs is the variable that shows closest association with all spirometric parameters in men&#44; while in women&#44; it is trunk lean mass&#46;</p><p id="par0265" class="elsevierStylePara elsevierViewall">In both sexes&#44; lean mass is mainly associated with FEV<span class="elsevierStyleInf">1</span> followed by FEV and PEF&#46; However&#44; it is not significantly related with the FEV<span class="elsevierStyleInf">1</span>&#47;FVC index&#46;</p></span><span id="sec0050" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0110">Conflict of Interests</span><p id="par0270" class="elsevierStylePara elsevierViewall">The authors state that they have no conflict of interests&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:10 [
        0 => array:3 [
          "identificador" => "xres858021"
          "titulo" => "Abstract"
          "secciones" => array:4 [
            0 => array:2 [
              "identificador" => "abst0005"
              "titulo" => "Introduction"
            ]
            1 => array:2 [
              "identificador" => "abst0010"
              "titulo" => "Methods"
            ]
            2 => array:2 [
              "identificador" => "abst0015"
              "titulo" => "Results"
            ]
            3 => array:2 [
              "identificador" => "abst0020"
              "titulo" => "Conclusions"
            ]
          ]
        ]
        1 => array:2 [
          "identificador" => "xpalclavsec852168"
          "titulo" => "Keywords"
        ]
        2 => array:3 [
          "identificador" => "xres858020"
          "titulo" => "Resumen"
          "secciones" => array:4 [
            0 => array:2 [
              "identificador" => "abst0025"
              "titulo" => "Introducci&#243;n"
            ]
            1 => array:2 [
              "identificador" => "abst0030"
              "titulo" => "M&#233;todos"
            ]
            2 => array:2 [
              "identificador" => "abst0035"
              "titulo" => "Resultados"
            ]
            3 => array:2 [
              "identificador" => "abst0040"
              "titulo" => "Conclusiones"
            ]
          ]
        ]
        3 => array:2 [
          "identificador" => "xpalclavsec852167"
          "titulo" => "Palabras clave"
        ]
        4 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Introduction"
        ]
        5 => array:3 [
          "identificador" => "sec0010"
          "titulo" => "Methods"
          "secciones" => array:3 [
            0 => array:2 [
              "identificador" => "sec0015"
              "titulo" => "Study Subjects"
            ]
            1 => array:3 [
              "identificador" => "sec0020"
              "titulo" => "Methods"
              "secciones" => array:2 [
                0 => array:2 [
                  "identificador" => "sec0025"
                  "titulo" => "Muscle Mass Assessment"
                ]
                1 => array:2 [
                  "identificador" => "sec0030"
                  "titulo" => "Evaluation of Lung Function"
                ]
              ]
            ]
            2 => array:2 [
              "identificador" => "sec0035"
              "titulo" => "Analysis"
            ]
          ]
        ]
        6 => array:2 [
          "identificador" => "sec0040"
          "titulo" => "Results"
        ]
        7 => array:2 [
          "identificador" => "sec0045"
          "titulo" => "Discussion and Conclusions"
        ]
        8 => array:2 [
          "identificador" => "sec0050"
          "titulo" => "Conflict of Interests"
        ]
        9 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2016-08-05"
    "fechaAceptado" => "2016-11-29"
    "PalabrasClave" => array:2 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec852168"
          "palabras" => array:4 [
            0 => "Fat-free soft tissue mass"
            1 => "Lean body mass"
            2 => "Dual energy X-ray absorptiometry"
            3 => "Spirometry"
          ]
        ]
      ]
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec852167"
          "palabras" => array:4 [
            0 => "Tejido blando no graso"
            1 => "Tejido magro"
            2 => "Absorciometr&#237;a dual fot&#243;nica de rayos X"
            3 => "Espirometr&#237;a"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "en" => array:3 [
        "titulo" => "Abstract"
        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Introduction</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Muscle mass maybe a determining factor in the variability of spirometry results in individuals of the same sex and age who have similar anthropometric characteristics&#46; The aim of this study was to determine the association between spirometric results from healthy individuals and their muscle mass assessed by dual energy X-ray absorptiometry &#40;DEXA&#41;&#46;</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Methods</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">A sample of 161 women and 144 men&#44; all healthy non-smokers&#44; was studied&#46; Ages ranged from18 to77<span class="elsevierStyleHsp" style=""></span>years&#46; For each subject&#44; spirometry results and total and regional lean mass values obtained by full body DEXA were recorded&#46; A descriptive analysis of the variables and a regression analysis were performed to study the relationship between spirometric variables and lean body mass&#44; correcting for age and body mass index &#40;BMI&#41;&#46;</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Results</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">In both sexes all muscle mass variables correlated positively and significantly with spirometric variables&#44; and to a greater extent in men&#46; After partial adjustment of correlations by age and BMI&#44; the factor which best explains the spirometric variables is the total lean body mass in men&#44; and trunk lean body mass in women&#46;</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Conclusions</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">In men&#44; muscle mass in the lower extremities is most closely associated with spirometric results&#46; In women&#44; it is the muscle mass of the trunk&#46; In both sexes muscle mass mainly affects FEV<span class="elsevierStyleInf">1</span>&#46;</p></span>"
        "secciones" => array:4 [
          0 => array:2 [
            "identificador" => "abst0005"
            "titulo" => "Introduction"
          ]
          1 => array:2 [
            "identificador" => "abst0010"
            "titulo" => "Methods"
          ]
          2 => array:2 [
            "identificador" => "abst0015"
            "titulo" => "Results"
          ]
          3 => array:2 [
            "identificador" => "abst0020"
            "titulo" => "Conclusions"
          ]
        ]
      ]
      "es" => array:3 [
        "titulo" => "Resumen"
        "resumen" => "<span id="abst0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Introducci&#243;n</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">La cantidad de masa muscular podr&#237;a ser un factor determinante que explicara la variabilidad de los resultados de la espirometr&#237;a en individuos del mismo sexo y edad y de caracter&#237;sticas antropom&#233;tricas similares&#46; El objetivo de este estudio es determinar si existe asociaci&#243;n entre los resultados espirom&#233;tricos de individuos sanos y su masa muscular estimada mediante absorciometr&#237;a de rayos X &#40;DEXA&#41;&#46;</p></span> <span id="abst0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">M&#233;todos</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Se estudi&#243; una muestra de 161 mujeres y 143 varones sanos&#44; no fumadores&#44; de 18 a 77<span class="elsevierStyleHsp" style=""></span>a&#241;os&#46; En cada sujeto se registraron los resultados de una espirometr&#237;a y los valores de la masa magra total y regional obtenidos mediante DEXA&#46; Se realiz&#243; un an&#225;lisis descriptivo de las variables y un an&#225;lisis de regresi&#243;n para estudiar las relaciones entre variables espirom&#233;tricas y masa magra&#44; corrigiendo los efectos que pudieran ejercer la edad y el &#237;ndice de masa corporal &#40;IMC&#41;&#46;</p></span> <span id="abst0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Resultados</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">En ambos sexos todas las variables de masa magra se correlacionan de forma positiva y significativa con las variables espirom&#233;tricas&#44; siendo estas relaciones mayores en los varones&#46; Al ajustar estas correlaciones de forma parcial por la edad y el IMC&#44; lo que mejor explica las variables espirom&#233;tricas es la masa magra en las extremidades inferiores en varones&#44; y la masa magra del tronco en mujeres&#46;</p></span> <span id="abst0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Conclusiones</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">En los varones&#44; la masa muscular en las extremidades inferiores es la que m&#225;s se asocia a los resultados espirom&#233;tricos&#46; En las mujeres es la masa muscular del tronco&#46; En ambos sexos la masa muscular influye principalmente sobre el volumen espiratorio forzado en el primer segundo &#40;FEV<span class="elsevierStyleInf">1</span>&#41;&#46;</p></span>"
        "secciones" => array:4 [
          0 => array:2 [
            "identificador" => "abst0025"
            "titulo" => "Introducci&#243;n"
          ]
          1 => array:2 [
            "identificador" => "abst0030"
            "titulo" => "M&#233;todos"
          ]
          2 => array:2 [
            "identificador" => "abst0035"
            "titulo" => "Resultados"
          ]
          3 => array:2 [
            "identificador" => "abst0040"
            "titulo" => "Conclusiones"
          ]
        ]
      ]
    ]
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0015">Please cite this article as&#58; Mart&#237;n Holguera R&#44; Turri&#243;n Nieves AI&#44; Rodr&#237;guez Torres R&#44; Alonso MC&#46; Asociaci&#243;n de la masa muscular determinada mediante DEXA con los resultados espirom&#233;tricos de individuos sanos&#46; Arch Bronconeumol&#46; 2017&#59;53&#58;375&#8211;380&#46;</p>"
      ]
    ]
    "multimedia" => array:6 [
      0 => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Fig&#46; 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 1152
            "Ancho" => 1578
            "Tamanyo" => 117729
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Principal component analysis in men with an overall explanation of 76&#46;07&#37; &#40;47&#46;1&#37; explains the first component and 28&#46;97&#37; the second&#41;&#46; FEV<span class="elsevierStyleInf">1</span>&#58; forced expiratory volume in 1<span class="elsevierStyleHsp" style=""></span>s&#59; FVC&#58; forced vital capacity&#59; BMI&#58; body mass index&#59; PEF&#58; peak expiratory flow&#59; LLM&#58; leg lean mass&#59; TLM&#58; total lean body mass&#59; TrLM&#58; trunk lean mass&#46;</p>"
        ]
      ]
      1 => array:7 [
        "identificador" => "fig0010"
        "etiqueta" => "Fig&#46; 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 1115
            "Ancho" => 1582
            "Tamanyo" => 120215
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Principal component analysis in women with an overall explanation of 73&#46;03&#37; &#40;46&#46;97&#37; explains the first component and 26&#46;05&#37; the second&#41;&#46; FEV<span class="elsevierStyleInf">1</span>&#58; Forced expiratory volume in 1<span class="elsevierStyleHsp" style=""></span>s&#59; FVC&#58; forced vital capacity&#59; BMI&#58; body mass index&#59; PEF&#58; peak expiratory flow&#59; LLM&#58; leg lean mass&#59; TLM&#58; total lean body mass&#59; TrLM&#58; trunk lean mass&#46;</p>"
        ]
      ]
      2 => array:8 [
        "identificador" => "tbl0005"
        "etiqueta" => "Table 1"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at1"
            "detalle" => "Table "
            "rol" => "short"
          ]
        ]
        "tabla" => array:3 [
          "leyenda" => "<p id="spar0060" class="elsevierStyleSimplePara elsevierViewall">FEF<span class="elsevierStyleInf">25&#37;&#8211;75&#37;</span>&#58; midexpiratory flow&#59; FEV<span class="elsevierStyleInf">1</span>&#58; forced expiratory volume in 1<span class="elsevierStyleHsp" style=""></span>s&#59; FVC&#58; forced vital capacity&#59; PEF&#58; peak expiratory flow&#59; LLM&#58; leg lean mass&#59; TLM&#58; total lean body mass&#59; TrLM&#58; trunk lean mass&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " rowspan="2" align="" valign="top" scope="col" style="border-bottom: 2px solid black"></th><th class="td" title="table-head  " align="left" valign="top" scope="col">Women&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col">Men&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " rowspan="2" align="center" valign="top" scope="col" style="border-bottom: 2px solid black"><span class="elsevierStyleItalic">p</span></th></tr><tr title="table-row"><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Mean&#44; Standard Deviation&#44; and Range&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Mean&#44; Standard Deviation&#44; and Range&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Age &#40;years&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">46&#46;4&#177;16&#46;8 &#40;18&#8211;75&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">43&#46;3&#177;16&#46;7 &#40;18&#8211;77&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Height &#40;cm&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">159&#46;9&#177;7 &#40;143&#8211;185&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">173&#46;2&#177;7&#46;5 &#40;154&#8211;190&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">&#42;&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Weight &#40;kg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">63&#46;8&#177;10&#46;1 &#40;44&#8211;97&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">80&#46;9&#177;12&#46;4 &#40;60&#8211;119&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">&#42;&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">BMI&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">25&#177;4&#46;3 &#40;16&#46;6&#8211;41&#46;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">26&#46;9&#177;3&#46;8 &#40;19&#46;7&#8211;40&#46;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">FVC &#40;ml&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3334&#46;2&#177;691&#46;5 &#40;1370&#8211;4720&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4711&#46;5&#177;848&#46;3 &#40;2610&#8211;7000&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">&#42;&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">FEV1 &#40;ml&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2830&#46;3&#177;614&#46;7 &#40;1150&#8211;4060&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3855&#46;9&#177;785&#46;3 &#40;1890&#8211;5920&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">&#42;&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">PEF&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6212&#46;1&#177;1407&#46;9 &#40;2380&#8211;10<span class="elsevierStyleHsp" style=""></span>390&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9066&#46;1&#177;1959&#46;7 &#40;3170&#8211;1&#46;3270&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">&#42;&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">FEF<span class="elsevierStyleInf">25&#37;&#8211;75&#37;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3226&#46;8&#177;943&#46;6 &#40;1040&#8211;6530&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3985&#46;7&#177;1315&#46;6 &#40;1340&#8211;8660&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">&#42;&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">FEV1&#47;FVC&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">84&#177;5&#46;8 &#40;70&#8211;99&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">82&#177;5&#46;8 &#40;71&#8211;95&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">TLM &#40;kg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">34&#46;9&#177;44&#46;9 &#40;23&#46;1&#8211;49&#46;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">55&#46;2&#177;75&#46;1 &#40;40&#46;6&#8211;77&#46;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">&#42;&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">TrLM &#40;kg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">15&#46;5&#177;22&#46;1 &#40;10&#46;5&#8211;23&#46;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">25&#46;2&#177;38&#46;8 &#40;12&#46;2&#8211;38&#46;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">&#42;&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">LLM &#40;kg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">12&#46;7&#177;19&#46;8 &#40;7&#46;7&#8211;18&#46;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">19&#46;3&#177;30 &#40;13&#46;9&#8211;27&#46;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">&#42;&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab1449463.png"
              ]
            ]
          ]
          "notaPie" => array:1 [
            0 => array:3 [
              "identificador" => "tblfn0005"
              "etiqueta" => "&#42;&#42;"
              "nota" => "<p class="elsevierStyleNotepara" id="npar0005"><span class="elsevierStyleItalic">p</span>&#60;0&#46;01 is statistically significant&#46;</p>"
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">Descriptive Statistics of Study Participants&#46;</p>"
        ]
      ]
      3 => array:8 [
        "identificador" => "tbl0010"
        "etiqueta" => "Table 2"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at2"
            "detalle" => "Table "
            "rol" => "short"
          ]
        ]
        "tabla" => array:3 [
          "leyenda" => "<p id="spar0070" class="elsevierStyleSimplePara elsevierViewall">FEF<span class="elsevierStyleInf">25&#37;&#8211;75&#37;</span>&#58; midexpiratory flow&#59; FEV1&#58; forced expiratory volume in 1<span class="elsevierStyleHsp" style=""></span>s&#59; FVC&#58; forced vital capacity&#59; PEF&#58; peak expiratory flow&#59; LLM&#58; leg lean mass&#59; TLM&#58; total lean body mass&#59; TrLM&#58; trunk lean mass&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">FVC&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">FEV1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">PEF&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">FEF<span class="elsevierStyleInf">25&#37;&#8211;75&#37;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">FEV1&#47;FVC&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">TLM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;603<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">&#42;&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;583<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">&#42;&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;371<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">&#42;&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;310<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">&#42;&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#8722;0&#46;098&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">TrLM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;529<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">&#42;&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;477<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">&#42;&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;336<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">&#42;&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;219<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">&#42;&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#8722;0&#46;166&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">LLM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;607<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">&#42;&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;599<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">&#42;&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;351<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">&#42;&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;354<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">&#42;&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#8722;0&#46;052&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab1449462.png"
              ]
            ]
          ]
          "notaPie" => array:1 [
            0 => array:3 [
              "identificador" => "tblfn0010"
              "etiqueta" => "&#42;&#42;"
              "nota" => "<p class="elsevierStyleNotepara" id="npar0010"><span class="elsevierStyleItalic">p</span>&#60;0&#46;01 is highly statistically significant&#46;</p>"
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0065" class="elsevierStyleSimplePara elsevierViewall">Partial Correlation Coefficients Between Muscle Mass Variables and Spirometric Variables Adjusting for Age and Body Mass Index in Men&#46;</p>"
        ]
      ]
      4 => array:8 [
        "identificador" => "tbl0015"
        "etiqueta" => "Table 3"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at3"
            "detalle" => "Table "
            "rol" => "short"
          ]
        ]
        "tabla" => array:2 [
          "leyenda" => "<p id="spar0080" class="elsevierStyleSimplePara elsevierViewall">FEF<span class="elsevierStyleInf">25&#37;&#8211;75&#37;</span>&#58; midexpiratory flow&#59; FEV<span class="elsevierStyleInf">1</span>&#58; forced expiratory volume in 1<span class="elsevierStyleHsp" style=""></span>s&#59; FVC&#58; forced vital capacity&#59; PEF&#58; peak expiratory flow&#59; LLM&#58; leg lean mass&#59; TLM&#58; total lean body mass&#59; TrLM&#58; trunk lean mass&#46;</p><p id="spar0085" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleSup">&#42;</span><span class="elsevierStyleItalic">p</span>&#60;0&#46;05 is statistically significant&#46;</p><p id="spar0090" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleSup">&#42;&#42;</span><span class="elsevierStyleItalic">p</span>&#60;0&#46;01 is highly statistically significant&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">FVC&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">FEV1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">PEF&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">FEF<span class="elsevierStyleInf">25&#37;&#8211;75&#37;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">FEV1&#47;FVC&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">TLM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;367<span class="elsevierStyleSup">&#42;&#42;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;341<span class="elsevierStyleSup">&#42;&#42;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;206<span class="elsevierStyleSup">&#42;&#42;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;165<span class="elsevierStyleSup">&#42;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#8722;0&#46;103&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">TrLM &#40;kg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;394<span class="elsevierStyleSup">&#42;&#42;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;373<span class="elsevierStyleSup">&#42;&#42;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;272<span class="elsevierStyleSup">&#42;&#42;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;183<span class="elsevierStyleSup">&#42;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#8722;0&#46;095&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">LLM &#40;kg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;359<span class="elsevierStyleSup">&#42;&#42;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;337<span class="elsevierStyleSup">&#42;&#42;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;178<span class="elsevierStyleSup">&#42;&#42;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;167<span class="elsevierStyleSup">&#42;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#8722;0&#46;094&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab1449461.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0075" class="elsevierStyleSimplePara elsevierViewall">Partial Correlation Coefficients Between Muscle Mass Variables and Spirometric Variables Adjusting for Age and Body Mass Index in Women&#46;</p>"
        ]
      ]
      5 => array:8 [
        "identificador" => "tbl0020"
        "etiqueta" => "Table 4"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at4"
            "detalle" => "Table "
            "rol" => "short"
          ]
        ]
        "tabla" => array:2 [
          "leyenda" => "<p id="spar0100" class="elsevierStyleSimplePara elsevierViewall">FEV<span class="elsevierStyleInf">1</span>&#58; forced expiratory volume in 1<span class="elsevierStyleHsp" style=""></span>s&#59; FVC&#58; forced vital capacity&#59; BMI&#58; body mass index&#59; PEF&#58; peak expiratory flow&#59; LLM&#58; leg lean mass&#59; TLM&#58; total lean mass&#59; TrLM&#58; trunk lean mass&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Equation&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Sex&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Adjusted <span class="elsevierStyleItalic">R</span><span class="elsevierStyleSup">2</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">FVC&#61;4159&#46;67&#8722;16&#46;4626&#42;Age&#8722;66&#46;2774&#42;BMI&#43;0&#46;157654&#42;LLM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">M&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">61&#46;66&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">FVC&#61;3496&#46;64&#8722;15&#46;6366&#42;Age&#8722;37&#46;1272&#42;BMI&#43;0&#46;113454&#42;LLM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">F&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">47&#46;80&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">FEV1&#61;3849&#46;83&#8722;23&#46;123&#42;Age&#8722;50&#46;7761&#42;BMI&#43;0&#46;122798&#42;LLM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">M&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">71&#46;71&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">FEV1&#61;3236&#46;55&#8722;19&#46;001&#42;Age&#8722;26&#46;2374&#42;BMI&#43;0&#46;0844262&#42;LLM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">F&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">57&#46;96&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">PEF&#61;7801&#46;62&#8722;40&#46;8775&#42;Age&#8722;55&#46;4911&#42;BMI&#43;0&#46;234124&#42;LLM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">M&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">34&#46;29&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">PEF&#61;6616&#46;24&#8722;34&#46;1297&#42;Age&#8722;22&#46;0113&#42;BMI&#43;0&#46;127834&#42;LLM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">F&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">27&#46;87&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">FVC&#61;4939&#46;19&#8722;28&#46;6842&#42;Age&#8722;55&#46;5342&#42;BMI&#43;0&#46;0996814&#42;TRLM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">M&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">56&#46;24&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">FVC&#61;3672&#46;79&#8722;20&#46;372&#42;Age&#8722;41&#46;0691&#42;BMI&#43;0&#46;101592&#42;TRLM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">F&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">49&#46;39&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">FEV1&#61;4543&#46;92&#8722;32&#46;8348&#42;Age&#8722;39&#46;124&#42;BMI&#43;0&#46;0710143&#42;TRLM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">M&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">65&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">FEV1&#61;3362&#46;43&#8722;22&#46;5101&#42;Age&#8722;29&#46;2664&#42;BMI&#43;0&#46;0760471&#42;TRLM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">F&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">59&#46;16&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">PEF&#61;8767&#46;04&#8722;58&#46;602&#42;Age&#8722;46&#46;8003&#42;BMI&#43;0&#46;162691&#42;TRLM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">M&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">33&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">PEF&#61;6296&#46;34&#8722;37&#46;9955&#42;Age&#8722;36&#46;0042&#42;BMI&#43;0&#46;159189&#42;TRLM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">F&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">31&#46;02&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">FVC&#61;4211&#46;3&#8722;20&#46;8774&#42;Age&#8722;74&#46;7347&#42;BMI&#43;0&#46;061934&#42;TLM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">M&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">61&#46;37&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">FVC&#61;3470&#46;12&#8722;17&#46;8657&#42;Age&#8722;42&#46;4918&#42;BMI&#43;0&#46;0487907&#42;TLM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">F&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">48&#46;16&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">FEV1&#61;3921&#46;89&#8722;26&#46;729&#42;Age&#8722;56&#46;2906&#42;BMI&#43;0&#46;047272&#42;TLM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">M&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">70&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">FEV1&#61;3230&#46;27&#8722;20&#46;7168&#42;Age&#8722;30&#46;0039&#42;BMI&#43;0&#46;0358316&#42;TLM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">F&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">58&#46;07&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">PEF&#61;7686&#46;54&#8722;46&#46;4255&#42;Age&#8722;74&#46;5144&#42;BMI&#43;0&#46;0978115&#42;TLM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">M&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">33&#46;36&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">PEF&#61;6383&#46;31&#8722;35&#46;7814&#42;Age&#8722;31&#46;457&#42;BMI&#43;0&#46;0621525&#42;TLM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">F&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">28&#46;67&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab1449460.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0095" class="elsevierStyleSimplePara elsevierViewall">Regression Equations and Adjusted <span class="elsevierStyleItalic">R</span><span class="elsevierStyleSup">2</span> Values Obtained in the Multiple Linear Regression Analysis in Men and Women&#46;</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:29 [
            0 => array:3 [
              "identificador" => "bib0150"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Factors influencing lung function&#58; are the predicted values for spirometry reliable enough&#63;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "S&#46; Ostrowski"
                            1 => "W&#46; Barud"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "J Physiol Pharmacol"
                        "fecha" => "2006"
                        "volumen" => "57"
                        "numero" => "Suppl&#46; 4"
                        "paginaInicial" => "263"
                        "paginaFinal" => "271"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17072054"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0155"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Sources of variation in forced expiratory volume in one second and forced vital capacity"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "S&#46; Chinn"
                            1 => "D&#46; Jarvis"
                            2 => "C&#46; Svanes"
                            3 => "P&#46; Burney"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1183/09031936.06.00073105"
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur Respir J"
                        "fecha" => "2006"
                        "volumen" => "27"
                        "paginaInicial" => "767"
                        "paginaFinal" => "773"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16585084"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0160"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Body mass&#44; fat percentage&#44; and fat free mass as reference variables for lung function&#58; effects on terms for age and sex"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "J&#46;E&#46; Cotes"
                            1 => "D&#46;J&#46; Chinn"
                            2 => "J&#46;W&#46; Reed"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Thorax"
                        "fecha" => "2001"
                        "volumen" => "56"
                        "paginaInicial" => "839"
                        "paginaFinal" => "844"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11641507"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0165"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The impact of body-weight components on forced spirometry in healthy Italians"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "E&#46;I&#46; Mohamed"
                            1 => "C&#46; Maiolo"
                            2 => "L&#46; Iacopino"
                            3 => "M&#46; Pepe"
                            4 => "N&#46; di Daniele"
                            5 => "A&#46; de Lorenzo"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s004080000089"
                      "Revista" => array:6 [
                        "tituloSerie" => "Lung"
                        "fecha" => "2002"
                        "volumen" => "180"
                        "paginaInicial" => "149"
                        "paginaFinal" => "159"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12177729"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0170"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Association between body composition and pulmonary function in elderly people&#58; The Korean Longitudinal Study on Health and Aging"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "S&#46; Lim"
                            1 => "S&#46;Y&#46; Kwon"
                            2 => "J&#46;W&#46; Yoon"
                            3 => "S&#46;Y&#46; Kim"
                            4 => "S&#46;H&#46; Choi"
                            5 => "Y&#46;J&#46; Park"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Obesity &#40;Silver Spring&#41;"
                        "fecha" => "2011"
                        "volumen" => "19"
                        "paginaInicial" => "631"
                        "paginaFinal" => "638"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0175"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The effect of body composition on pulmonary function"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "J&#46;E&#46; Park"
                            1 => "J&#46;H&#46; Chung"
                            2 => "K&#46;H&#46; Lee"
                            3 => "K&#46;C&#46; Shin"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Tuberc Respir Dis &#40;Seoul&#41;"
                        "fecha" => "2012"
                        "volumen" => "72"
                        "paginaInicial" => "433"
                        "paginaFinal" => "440"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0180"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Dual-energy X-ray absorptiometry in the clinical evaluation of body composition and bone mineral density in patients with chronic obstructive pulmonary disease"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "M&#46;P&#46; Engelen"
                            1 => "A&#46;M&#46; Schols"
                            2 => "G&#46;A&#46; Heidendal"
                            3 => "E&#46;F&#46; Wouters"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Clin Nutr"
                        "fecha" => "1998"
                        "volumen" => "68"
                        "paginaInicial" => "1298"
                        "paginaFinal" => "1303"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9846862"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0185"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Dual-energy X-ray absorptiometry is the method of choice to assess body composition in COPD"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "A&#46; Miller"
                            1 => "B&#46;J&#46; Strauss"
                            2 => "S&#46; Mol"
                            3 => "A&#46; Kyoong"
                            4 => "P&#46;H&#46; Holmes"
                            5 => "P&#46; Finlay"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Respirology"
                        "fecha" => "2009"
                        "volumen" => "14"
                        "paginaInicial" => "411"
                        "paginaFinal" => "418"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19353776"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib0190"
              "etiqueta" => "9"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Bedside methods versus dual energy X-ray absorptiometry for body composition measurement in COPD"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "M&#46;C&#46; Steiner"
                            1 => "R&#46;L&#46; Barton"
                            2 => "S&#46;J&#46; Singh"
                            3 => "M&#46;D&#46; Morgan"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur Respir J"
                        "fecha" => "2002"
                        "volumen" => "19"
                        "paginaInicial" => "626"
                        "paginaFinal" => "631"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11998990"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib0195"
              "etiqueta" => "10"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Guidelines for the evaluation and treatment of muscle dysfunction in patients with chronic obstructive pulmonary disease"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "E&#46; Barreiro"
                            1 => "V&#46; Bustamante"
                            2 => "P&#46; Cejudo"
                            3 => "J&#46;B&#46; Galdiz"
                            4 => "J&#46; Gea"
                            5 => "P&#46; de Lucas"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.arbres.2015.04.011"
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Bronconeumol"
                        "fecha" => "2015"
                        "volumen" => "51"
                        "paginaInicial" => "384"
                        "paginaFinal" => "395"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26072153"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib0200"
              "etiqueta" => "11"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Muscle dysfunction in chronic obstructive pulmonary disease&#58; update on causes and biological findings"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "J&#46; Gea"
                            1 => "S&#46; Pascual"
                            2 => "C&#46; Casadevall"
                            3 => "M&#46; Orozco-Levi"
                            4 => "E&#46; Barreiro"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.3978/j.issn.2072-1439.2015.08.04"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Thorac Dis"
                        "fecha" => "2015"
                        "volumen" => "7"
                        "paginaInicial" => "E418"
                        "paginaFinal" => "E438"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26623119"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib0205"
              "etiqueta" => "12"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Lean mass predicts asthma better than fat mass among females"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "A&#46; Sood"
                            1 => "C&#46; Qualls"
                            2 => "R&#46; Li"
                            3 => "M&#46; Schuyler"
                            4 => "W&#46;S&#46; Beckett"
                            5 => "L&#46;J&#46; Smith"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1183/09031936.00193709"
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur Respir J"
                        "fecha" => "2011"
                        "volumen" => "37"
                        "paginaInicial" => "65"
                        "paginaFinal" => "71"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20525713"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib0210"
              "etiqueta" => "13"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Body composition in severe refractory asthma&#58; comparison with COPD patients and healthy smokers"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M&#46; Minas"
                            1 => "A&#46;I&#46; Papaioannou"
                            2 => "A&#46; Tsaroucha"
                            3 => "Z&#46; Daniil"
                            4 => "C&#46; Hatzoglou"
                            5 => "M&#46; Sgantzos"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1371/journal.pone.0013233"
                      "Revista" => array:5 [
                        "tituloSerie" => "PLoS ONE"
                        "fecha" => "2010"
                        "volumen" => "5"
                        "paginaInicial" => "e13233"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20949085"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib0215"
              "etiqueta" => "14"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Effect of physical training on fat-free mass in patients with chronic obstructive pulmonary disease &#40;COPD&#41;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "M&#46; Emtner"
                            1 => "R&#46; Hallin"
                            2 => "R&#46;H&#46; Arnardottir"
                            3 => "C&#46; Janson"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.3109/03009734.2014.990124"
                      "Revista" => array:6 [
                        "tituloSerie" => "Ups J Med Sci"
                        "fecha" => "2015"
                        "volumen" => "120"
                        "paginaInicial" => "52"
                        "paginaFinal" => "58"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25430624"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib0220"
              "etiqueta" => "15"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Body composition and health-related quality of life in patients with obstructive airways disease"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "R&#46; Shoup"
                            1 => "G&#46; Dalsky"
                            2 => "S&#46; Warner"
                            3 => "M&#46; Davies"
                            4 => "M&#46; Connors"
                            5 => "M&#46; Khan"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur Respir J"
                        "fecha" => "1997"
                        "volumen" => "10"
                        "paginaInicial" => "1576"
                        "paginaFinal" => "1580"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9230250"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib0225"
              "etiqueta" => "16"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Body mass and fat-free mass indices in COPD&#58; relation with variables expressing disease severity"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "E&#46; Ischaki"
                            1 => "G&#46; Papatheodorou"
                            2 => "E&#46; Gaki"
                            3 => "I&#46; Papa"
                            4 => "N&#46; Koulouris"
                            5 => "S&#46; Loukides"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1378/chest.06-2789"
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "2007"
                        "volumen" => "132"
                        "paginaInicial" => "164"
                        "paginaFinal" => "169"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17505043"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib0230"
              "etiqueta" => "17"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Body mass&#44; fat-free body mass&#44; and prognosis in patients with chronic obstructive pulmonary disease from a random population sample&#58; findings from the Copenhagen City Heart Study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "J&#46; Vestbo"
                            1 => "E&#46; Prescott"
                            2 => "T&#46; Almdal"
                            3 => "M&#46; Dahl"
                            4 => "B&#46;G&#46; Nordestgaard"
                            5 => "T&#46; Andersen"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1164/rccm.200506-969OC"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Respir Crit Care Med"
                        "fecha" => "2006"
                        "volumen" => "173"
                        "paginaInicial" => "79"
                        "paginaFinal" => "83"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16368793"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib0235"
              "etiqueta" => "18"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "An evaluation of patterns of change in total and regional body fat mass in healthy Spanish subjects using dual-energy X-ray absorptiometry &#40;DXA&#41;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "S&#46;A&#46; Aguado Henche"
                            1 => "R&#46;R&#46; Torres"
                            2 => "L&#46;G&#46; Pellico"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1038/sj.ejcn.1602883"
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur J Clin Nutr"
                        "fecha" => "2008"
                        "volumen" => "62"
                        "paginaInicial" => "1440"
                        "paginaFinal" => "1448"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17717537"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib0240"
              "etiqueta" => "19"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Recomendaciones SEPAR en espirometr&#237;a forzada"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "J&#46; Sanchis"
                            1 => "P&#46; Casan Clar&#225;"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:3 [
                        "fecha" => "1998"
                        "editorial" => "Respira"
                        "editorialLocalizacion" => "Barcelona"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib0245"
              "etiqueta" => "20"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Sex and age differences in pulmonary mechanics in normal nonsmoking subjects"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "G&#46;J&#46; Gibson"
                            1 => "N&#46;B&#46; Pride"
                            2 => "C&#46; O&#8217;cain"
                            3 => "R&#46; Quagliato"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Appl Physiol"
                        "fecha" => "1976"
                        "volumen" => "41"
                        "paginaInicial" => "20"
                        "paginaFinal" => "25"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/972127"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bib0250"
              "etiqueta" => "21"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "An evaluation of lean body mass in the Spanish Population using X-ray absoptiometry &#40;DXA&#41;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "S&#46;S&#46; Aguado Henche"
                            1 => "R&#46; Rodr&#237;guez Torres"
                            2 => "L&#46; G&#243;mez Pellico"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Int J Body Compos Res"
                        "fecha" => "2006"
                        "volumen" => "2"
                        "paginaInicial" => "67"
                        "paginaFinal" => "74"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            21 => array:3 [
              "identificador" => "bib0255"
              "etiqueta" => "22"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Relationship between body composition&#44; peripheral muscle strength and functional exercise capacity in patients with severe chronic obstructive pulmonary disease"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "C&#46;M&#46; Hillman"
                            1 => "E&#46;L&#46; Heinecke"
                            2 => "J&#46;W&#46; Hii"
                            3 => "N&#46;M&#46; Cecins"
                            4 => "S&#46;C&#46; Jenkins"
                            5 => "P&#46;R&#46; Eastwood"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/j.1445-5994.2012.02771.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "Intern Med J"
                        "fecha" => "2012"
                        "volumen" => "42"
                        "paginaInicial" => "578"
                        "paginaFinal" => "581"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22616963"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            22 => array:3 [
              "identificador" => "bib0260"
              "etiqueta" => "23"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The loss of skeletal muscle strength&#44; mass&#44; and quality in older adults&#58; the health&#44; aging and body composition study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "B&#46;H&#46; Goodpaster"
                            1 => "S&#46;W&#46; Park"
                            2 => "T&#46;B&#46; Harris"
                            3 => "S&#46;B&#46; Kritchevsky"
                            4 => "M&#46; Nevitt"
                            5 => "A&#46;V&#46; Schwartz"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Gerontol A Biol Sci Med Sci"
                        "fecha" => "2006"
                        "volumen" => "61"
                        "paginaInicial" => "1059"
                        "paginaFinal" => "1064"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17077199"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            23 => array:3 [
              "identificador" => "bib0265"
              "etiqueta" => "24"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Loss of skeletal muscle mass in aging&#58; examining the relationship of starvation&#44; sarcopenia and cachexia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "D&#46;R&#46; Thomas"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.clnu.2007.03.008"
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Nutr"
                        "fecha" => "2007"
                        "volumen" => "26"
                        "paginaInicial" => "389"
                        "paginaFinal" => "399"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17499396"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            24 => array:3 [
              "identificador" => "bib0270"
              "etiqueta" => "25"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Identification and comparison of the predictors of maximal inspiratory force and handgrip in a healthy elderly population&#46; The proof study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "F&#46; Costes"
                            1 => "S&#46; Celle"
                            2 => "M&#46; Garet"
                            3 => "M&#46; Kossovsky"
                            4 => "F&#46; Roche"
                            5 => "J&#46;C&#46; Barthelemy"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.clnu.2015.07.016"
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Nutr"
                        "fecha" => "2016"
                        "volumen" => "35"
                        "paginaInicial" => "963"
                        "paginaFinal" => "967"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26233802"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            25 => array:3 [
              "identificador" => "bib0275"
              "etiqueta" => "26"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The prevalence of quadriceps weakness in COPD and the relationship with disease severity"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "J&#46;M&#46; Seymour"
                            1 => "M&#46;A&#46; Spruit"
                            2 => "N&#46;S&#46; Hopkinson"
                            3 => "S&#46;A&#46; Natanek"
                            4 => "W&#46;D&#46; Man"
                            5 => "A&#46; Jackson"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1183/09031936.00104909"
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur Respir J"
                        "fecha" => "2010"
                        "volumen" => "36"
                        "paginaInicial" => "81"
                        "paginaFinal" => "88"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19897554"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            26 => array:3 [
              "identificador" => "bib0280"
              "etiqueta" => "27"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Aging and the respiratory system"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "A&#46; Rossi"
                            1 => "A&#46; Ganassini"
                            2 => "C&#46; Tantucci"
                            3 => "V&#46; Grassi"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Aging &#40;Milano&#41;"
                        "fecha" => "1996"
                        "volumen" => "8"
                        "paginaInicial" => "143"
                        "paginaFinal" => "161"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            27 => array:3 [
              "identificador" => "bib0285"
              "etiqueta" => "28"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Age-associated changes in skeletal muscles and their effect on mobility&#58; an operational diagnosis of sarcopenia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "F&#46; Lauretani"
                            1 => "C&#46;R&#46; Russo"
                            2 => "S&#46; Bandinelli"
                            3 => "B&#46; Bartali"
                            4 => "C&#46; Cavazzini"
                            5 => "A&#46; di Iorio"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J Appl Physiol &#40;1985&#41;"
                        "fecha" => "2003"
                        "volumen" => "95"
                        "paginaInicial" => "1851"
                        "paginaFinal" => "1860"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            28 => array:3 [
              "identificador" => "bib0290"
              "etiqueta" => "29"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Age adjustment of body composition"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "S&#46;S&#46; Aguado Henche"
                            1 => "R&#46; Rodr&#237;guez Torres"
                            2 => "L&#46; G&#243;mez Pellico"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Res Adv Clin Nutr"
                        "fecha" => "2009"
                        "volumen" => "1"
                        "paginaInicial" => "1"
                        "paginaFinal" => "18"
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/15792129/0000005300000007/v1_201706290145/S1579212917301751/v1_201706290145/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "9374"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Original Articles"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/15792129/0000005300000007/v1_201706290145/S1579212917301751/v1_201706290145/en/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212917301751?idApp=UINPBA00003Z"
]
Share
Journal Information

Statistics

Follow this link to access the full text of the article

Original article
Relationship of Muscle Mass Determined by DEXA with Spirometric Results in Healthy Individuals
Asociación de la masa muscular determinada mediante DEXA con los resultados espirométricos de individuos sanos
Rafael Martín Holgueraa,
Corresponding author
rafael.martin@uah.es

Corresponding author.
, Ana Isabel Turrión Nievesa,b, Rosa Rodríguez Torresa, María Concepción Alonsoc
a Departamento de Cirugía y Ciencias Médico Sociales, Unidad Docente de Anatomía y Embriología Humanas, Facultad de Medicina, Universidad de Alcalá de Henares, Alcalá de Henares, Madrid, Spain
b Departamento de Medicina Interna, Servicio de ESI-Reumatología, Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Madrid, Spain
c Departamento de Física y Matemáticas, Unidad docente de Matemáticas, Edificio Politécnico, Universidad de Alcalá de Henares, Alcalá de Henares, Madrid, Spain
Read
5078
Times
was read the article
1850
Total PDF
3228
Total HTML
Share statistics
 array:24 [
  "pii" => "S1579212917301751"
  "issn" => "15792129"
  "doi" => "10.1016/j.arbr.2017.05.006"
  "estado" => "S300"
  "fechaPublicacion" => "2017-07-01"
  "aid" => "1521"
  "copyright" => "SEPAR"
  "copyrightAnyo" => "2016"
  "documento" => "article"
  "crossmark" => 1
  "subdocumento" => "fla"
  "cita" => "Arch Bronconeumol. 2017;53:375-80"
  "abierto" => array:3 [
    "ES" => false
    "ES2" => false
    "LATM" => false
  ]
  "gratuito" => false
  "lecturas" => array:2 [
    "total" => 1342
    "formatos" => array:3 [
      "EPUB" => 133
      "HTML" => 777
      "PDF" => 432
    ]
  ]
  "Traduccion" => array:1 [
    "es" => array:19 [
      "pii" => "S0300289616303519"
      "issn" => "03002896"
      "doi" => "10.1016/j.arbres.2016.11.020"
      "estado" => "S300"
      "fechaPublicacion" => "2017-07-01"
      "aid" => "1521"
      "copyright" => "SEPAR"
      "documento" => "article"
      "crossmark" => 1
      "subdocumento" => "fla"
      "cita" => "Arch Bronconeumol. 2017;53:375-80"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 4023
        "formatos" => array:3 [
          "EPUB" => 138
          "HTML" => 3295
          "PDF" => 590
        ]
      ]
      "es" => array:13 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Original</span>"
        "titulo" => "Asociaci&#243;n de la masa muscular determinada mediante DEXA con los resultados espirom&#233;tricos de individuos sanos"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "tieneResumen" => array:2 [
          0 => "es"
          1 => "en"
        ]
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "375"
            "paginaFinal" => "380"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Relationship of Muscle Mass Determined by DEXA with Spirometric Results in Healthy Individuals"
          ]
        ]
        "contieneResumen" => array:2 [
          "es" => true
          "en" => true
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "resumenGrafico" => array:2 [
          "original" => 0
          "multimedia" => array:7 [
            "identificador" => "fig0005"
            "etiqueta" => "Figura 1"
            "tipo" => "MULTIMEDIAFIGURA"
            "mostrarFloat" => true
            "mostrarDisplay" => false
            "figura" => array:1 [
              0 => array:4 [
                "imagen" => "gr1.jpeg"
                "Alto" => 1152
                "Ancho" => 1578
                "Tamanyo" => 113868
              ]
            ]
            "descripcion" => array:1 [
              "es" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">An&#225;lisis de componentes principales en varones con un 76&#44;07&#37; de explicaci&#243;n global &#40;47&#44;1&#37; que explica la primera componente y 28&#44;97&#37; la segunda&#41;&#46;</p> <p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">FEV<span class="elsevierStyleInf">1</span>&#58; volumen espiratorio forzado en el primer segundo&#59; FVC&#58; capacidad vital forzada&#59; IMC&#58; &#237;ndice de masa corporal&#59; PEF&#58; pico flujo espiratorio&#59; TNGP&#58; tejido magro de las extremidades inferiores&#59; TNGT&#58; tejido magro total&#59; TNGTR&#58; tejido magro del tronco&#46;</p>"
            ]
          ]
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "Rafael Mart&#237;n Holguera, Ana Isabel Turri&#243;n Nieves, Rosa Rodr&#237;guez Torres, Mar&#237;a Concepci&#243;n Alonso"
            "autores" => array:4 [
              0 => array:2 [
                "nombre" => "Rafael"
                "apellidos" => "Mart&#237;n Holguera"
              ]
              1 => array:2 [
                "nombre" => "Ana Isabel"
                "apellidos" => "Turri&#243;n Nieves"
              ]
              2 => array:2 [
                "nombre" => "Rosa"
                "apellidos" => "Rodr&#237;guez Torres"
              ]
              3 => array:2 [
                "nombre" => "Mar&#237;a Concepci&#243;n"
                "apellidos" => "Alonso"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S1579212917301751"
          "doi" => "10.1016/j.arbr.2017.05.006"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => false
            "ES2" => false
            "LATM" => false
          ]
          "gratuito" => false
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212917301751?idApp=UINPBA00003Z"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289616303519?idApp=UINPBA00003Z"
      "url" => "/03002896/0000005300000007/v2_201706291228/S0300289616303519/v2_201706291228/es/main.assets"
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S1579212916302683"
    "issn" => "15792129"
    "doi" => "10.1016/j.arbr.2016.11.006"
    "estado" => "S300"
    "fechaPublicacion" => "2017-07-01"
    "aid" => "1472"
    "copyright" => "SEPAR"
    "documento" => "article"
    "crossmark" => 1
    "subdocumento" => "fla"
    "cita" => "Arch Bronconeumol. 2017;53:381-6"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 2358
      "formatos" => array:3 [
        "EPUB" => 142
        "HTML" => 1547
        "PDF" => 669
      ]
    ]
    "en" => array:12 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Original Article</span>"
      "titulo" => "Association of Gene Polymorphisms in Interleukin 6 in Infantile Bronchial Asthma"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "381"
          "paginaFinal" => "386"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Asociaci&#243;n entre polimorfismos gen&#233;ticos de la interleucina 6 y el asma bronquial en ni&#241;os"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Eva Babusikova, Jana Jurecekova, Milos Jesenak, Andrea Evinova"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "Eva"
              "apellidos" => "Babusikova"
            ]
            1 => array:2 [
              "nombre" => "Jana"
              "apellidos" => "Jurecekova"
            ]
            2 => array:2 [
              "nombre" => "Milos"
              "apellidos" => "Jesenak"
            ]
            3 => array:2 [
              "nombre" => "Andrea"
              "apellidos" => "Evinova"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0300289616302551"
        "doi" => "10.1016/j.arbres.2016.09.012"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289616302551?idApp=UINPBA00003Z"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212916302683?idApp=UINPBA00003Z"
    "url" => "/15792129/0000005300000007/v1_201706290145/S1579212916302683/v1_201706290145/en/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S157921291730174X"
    "issn" => "15792129"
    "doi" => "10.1016/j.arbr.2017.05.005"
    "estado" => "S300"
    "fechaPublicacion" => "2017-07-01"
    "aid" => "1522"
    "copyright" => "SEPAR"
    "documento" => "article"
    "crossmark" => 1
    "subdocumento" => "fla"
    "cita" => "Arch Bronconeumol. 2017;53:366-74"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 4056
      "formatos" => array:3 [
        "EPUB" => 175
        "HTML" => 3213
        "PDF" => 668
      ]
    ]
    "en" => array:13 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Original article</span>"
      "titulo" => "Etiology of Bronchiectasis in a Cohort of 2047 Patients&#46; An Analysis of the Spanish Historical Bronchiectasis Registry"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "366"
          "paginaFinal" => "374"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Etiolog&#237;a de las bronquiectasias en una cohorte de 2&#46;047 pacientes&#46; An&#225;lisis del registro hist&#243;rico espa&#241;ol"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Fig&#46; 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 1971
              "Ancho" => 1628
              "Tamanyo" => 173686
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Flow chart&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Casilda Olveira, Alicia Padilla, Miguel-&#193;ngel Mart&#237;nez-Garc&#237;a, David de la Rosa, Rosa-Mar&#237;a Gir&#243;n, Montserrat Vendrell, Luis M&#225;iz, Luis Border&#237;as, Eva Polverino, Eva Mart&#237;nez-Morag&#243;n, Olga Rajas, Francisco Casas, Rosa Cordovilla, Javier de Gracia"
          "autores" => array:14 [
            0 => array:2 [
              "nombre" => "Casilda"
              "apellidos" => "Olveira"
            ]
            1 => array:2 [
              "nombre" => "Alicia"
              "apellidos" => "Padilla"
            ]
            2 => array:2 [
              "nombre" => "Miguel-&#193;ngel"
              "apellidos" => "Mart&#237;nez-Garc&#237;a"
            ]
            3 => array:2 [
              "nombre" => "David"
              "apellidos" => "de la Rosa"
            ]
            4 => array:2 [
              "nombre" => "Rosa-Mar&#237;a"
              "apellidos" => "Gir&#243;n"
            ]
            5 => array:2 [
              "nombre" => "Montserrat"
              "apellidos" => "Vendrell"
            ]
            6 => array:2 [
              "nombre" => "Luis"
              "apellidos" => "M&#225;iz"
            ]
            7 => array:2 [
              "nombre" => "Luis"
              "apellidos" => "Border&#237;as"
            ]
            8 => array:2 [
              "nombre" => "Eva"
              "apellidos" => "Polverino"
            ]
            9 => array:2 [
              "nombre" => "Eva"
              "apellidos" => "Mart&#237;nez-Morag&#243;n"
            ]
            10 => array:2 [
              "nombre" => "Olga"
              "apellidos" => "Rajas"
            ]
            11 => array:2 [
              "nombre" => "Francisco"
              "apellidos" => "Casas"
            ]
            12 => array:2 [
              "nombre" => "Rosa"
              "apellidos" => "Cordovilla"
            ]
            13 => array:2 [
              "nombre" => "Javier"
              "apellidos" => "de Gracia"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0300289616303520"
        "doi" => "10.1016/j.arbres.2016.12.003"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289616303520?idApp=UINPBA00003Z"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S157921291730174X?idApp=UINPBA00003Z"
    "url" => "/15792129/0000005300000007/v1_201706290145/S157921291730174X/v1_201706290145/en/main.assets"
  ]
  "en" => array:20 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Original article</span>"
    "titulo" => "Relationship of Muscle Mass Determined by DEXA with Spirometric Results in Healthy Individuals"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "375"
        "paginaFinal" => "380"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "Rafael Mart&#237;n Holguera, Ana Isabel Turri&#243;n Nieves, Rosa Rodr&#237;guez Torres, Mar&#237;a Concepci&#243;n Alonso"
        "autores" => array:4 [
          0 => array:4 [
            "nombre" => "Rafael"
            "apellidos" => "Mart&#237;n Holguera"
            "email" => array:1 [
              0 => "rafael&#46;martin&#64;uah&#46;es"
            ]
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "Ana Isabel"
            "apellidos" => "Turri&#243;n Nieves"
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "Rosa"
            "apellidos" => "Rodr&#237;guez Torres"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "Mar&#237;a Concepci&#243;n"
            "apellidos" => "Alonso"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">c</span>"
                "identificador" => "aff0015"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:3 [
          0 => array:3 [
            "entidad" => "Departamento de Cirug&#237;a y Ciencias M&#233;dico Sociales&#44; Unidad Docente de Anatom&#237;a y Embriolog&#237;a Humanas&#44; Facultad de Medicina&#44; Universidad de Alcal&#225; de Henares&#44; Alcal&#225; de Henares&#44; Madrid&#44; Spain"
            "etiqueta" => "a"
            "identificador" => "aff0005"
          ]
          1 => array:3 [
            "entidad" => "Departamento de Medicina Interna&#44; Servicio de ESI-Reumatolog&#237;a&#44; Hospital Universitario Pr&#237;ncipe de Asturias&#44; Alcal&#225; de Henares&#44; Madrid&#44; Spain"
            "etiqueta" => "b"
            "identificador" => "aff0010"
          ]
          2 => array:3 [
            "entidad" => "Departamento de F&#237;sica y Matem&#225;ticas&#44; Unidad docente de Matem&#225;ticas&#44; Edificio Polit&#233;cnico&#44; Universidad de Alcal&#225; de Henares&#44; Alcal&#225; de Henares&#44; Madrid&#44; Spain"
            "etiqueta" => "c"
            "identificador" => "aff0015"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Asociaci&#243;n de la masa muscular determinada mediante DEXA con los resultados espirom&#233;tricos de individuos sanos"
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:7 [
        "identificador" => "fig0010"
        "etiqueta" => "Fig&#46; 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 1115
            "Ancho" => 1582
            "Tamanyo" => 120215
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Principal component analysis in women with an overall explanation of 73&#46;03&#37; &#40;46&#46;97&#37; explains the first component and 26&#46;05&#37; the second&#41;&#46; FEV<span class="elsevierStyleInf">1</span>&#58; Forced expiratory volume in 1<span class="elsevierStyleHsp" style=""></span>s&#59; FVC&#58; forced vital capacity&#59; BMI&#58; body mass index&#59; PEF&#58; peak expiratory flow&#59; LLM&#58; leg lean mass&#59; TLM&#58; total lean body mass&#59; TrLM&#58; trunk lean mass&#46;</p>"
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0065">Introduction</span><p id="par0005" class="elsevierStylePara elsevierViewall">Forced spirometry is the principal test for evaluating lung function in individuals&#46; The main factors determining spirometric results are sex&#44; age&#44; height&#44; and weight&#44; and these variables are used to produce equations predicting normal reference values&#46; Several authors<a class="elsevierStyleCrossRefs" href="#bib0150"><span class="elsevierStyleSup">1&#44;2</span></a> believe that there must be other factors that determine spirometry results&#44; which would explain the variability in test values obtained in healthy individuals with similar characteristics&#46; The premise of this study is that one of the factors that might cause this variability could be muscle mass&#46; Although some previous studies<a class="elsevierStyleCrossRefs" href="#bib0160"><span class="elsevierStyleSup">3&#8211;6</span></a> have already evaluated this possibility&#44; we believe that the influence of an individual&#39;s muscle mass on spirometric results has not been clearly established&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">The technique of choice for evaluating muscle mass is dual energy X-ray absorptiometry &#40;DEXA&#41;&#46; This is an imaging technique used to quantify lean body mass &#40;fat-free mass&#41; in both the whole body and in different body regions&#46; Lean body mass is an estimation of muscle mass&#46; This test offers reliable measurements that are comparable over time&#46; It is&#44; moreover&#44; a technique widely used in respiratory clinics&#44;<a class="elsevierStyleCrossRefs" href="#bib0180"><span class="elsevierStyleSup">7&#8211;9</span></a> mainly for assessing muscle mass in patients with chronic obstructive pulmonary disease &#40;COPD&#41;&#44; who often present muscle dysfunction of the ventilatory system and the lower limbs&#46;<a class="elsevierStyleCrossRefs" href="#bib0195"><span class="elsevierStyleSup">10&#44;11</span></a> Muscle training improves exercise tolerance&#44; muscle strength&#44; dyspnea&#44; fatigue&#44; and quality of life in these patients&#46; The impact of muscle mass on the symptoms and prognosis of asthmatics has also been studied&#46;<a class="elsevierStyleCrossRefs" href="#bib0205"><span class="elsevierStyleSup">12&#44;13</span></a> Increasing numbers of studies are using DEXA to evaluate the outcome of muscle training in respiratory rehabilitation programs in COPD patients and to determine their prognosis&#46;<a class="elsevierStyleCrossRefs" href="#bib0215"><span class="elsevierStyleSup">14&#8211;17</span></a> For this reason&#44; we identified a need to establish the association between spirometric values and muscle mass parameters determined by DEXA in healthy individuals&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">The aim of this study was to quantify the association between spirometric variables and muscle mass estimated by DEXA&#44; to establish whether muscle mass is an important determinant in the spirometric results of healthy individuals&#44; and to help establish the normality of this association&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0070">Methods</span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">Study Subjects</span><p id="par0025" class="elsevierStylePara elsevierViewall">The study population consisted of 305 healthy subjects of Caucasian origin &#40;144 men and 161 women&#41;&#44; aged between 18 and 77 years&#44; inclusive&#46; Participation in the study was voluntary&#44; and all subjects were recruited from an urban setting in the environs of the Universidad de Alcal&#225; de Henares&#46; Subjects were matched in terms of lifestyle and diet&#44; and had performed physical exercise sporadically throughout their lives&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">Study inclusion criteria were&#58;<ul class="elsevierStyleList" id="lis0005"><li class="elsevierStyleListItem" id="lsti0005"><span class="elsevierStyleLabel">-</span><p id="par0035" class="elsevierStylePara elsevierViewall">Never-smoker&#46;</p></li><li class="elsevierStyleListItem" id="lsti0010"><span class="elsevierStyleLabel">-</span><p id="par0040" class="elsevierStylePara elsevierViewall">No metabolic diseases or pharmacological treatments that might alter metabolism&#46;</p></li><li class="elsevierStyleListItem" id="lsti0015"><span class="elsevierStyleLabel">-</span><p id="par0045" class="elsevierStylePara elsevierViewall">No muscle or neuromuscular diseases&#46;</p></li><li class="elsevierStyleListItem" id="lsti0020"><span class="elsevierStyleLabel">-</span><p id="par0050" class="elsevierStylePara elsevierViewall">No thoracic abnormalities&#44; determined as a thoracic index within the mean for their age&#44; plus or minus 2 standard deviations&#46;</p></li><li class="elsevierStyleListItem" id="lsti0025"><span class="elsevierStyleLabel">-</span><p id="par0055" class="elsevierStylePara elsevierViewall">No obvious changes in the physiological curvature of the spine&#46;</p></li><li class="elsevierStyleListItem" id="lsti0030"><span class="elsevierStyleLabel">-</span><p id="par0060" class="elsevierStylePara elsevierViewall">No neoplasms&#44; cardiovascular diseases&#44; chronic bronchial diseases&#44; or episodes of spontaneous pneumothorax&#46;</p></li></ul></p><p id="par0065" class="elsevierStylePara elsevierViewall">All individuals had spirometric results within normal limits &#40;forced vital capacity &#91;FVC&#93; and forced expiratory volume in 1<span class="elsevierStyleHsp" style=""></span>s &#91;FEV<span class="elsevierStyleInf">1</span>&#93; over 80&#37; predicted&#44; and FEV<span class="elsevierStyleInf">1</span>&#47;FVC greater than 70&#37; and less than 80&#37;&#41;&#44; and agreed voluntarily to undergo the specific study tests&#44; after giving informed consent&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0080">Methods</span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0085">Muscle Mass Assessment</span><p id="par0070" class="elsevierStylePara elsevierViewall">To quantify muscle mass in each individual&#44; a whole-body dual energy X-ray absorptiometry &#40;DEXA&#41; was performed&#44; from which overall and regional lean body mass &#40;fat-free soft tissue mass&#41; values were obtained&#44; providing an estimation of muscle mass&#46;</p><p id="par0075" class="elsevierStylePara elsevierViewall">This technique uses a highly stable X-ray generator to produce a spectrum of broad energy band levels&#46; The apparatus consists of NaI crystal scintillation detectors placed in tandem&#46; The source of radiation and the detectors are placed opposite each other and mechanically connected so that they move simultaneously&#46; The light beam passes in a posteroanterior direction through the tissue while the patient lies perfectly still in a supine position&#46; Energy is absorbed depending on the density of the tissue that it passes through&#58; absorption is zero in air&#44; small in fat&#44; greater in soft tissues&#44; and very significant in bone&#46; Photons that have not been absorbed are captured by the detector&#44; so the density of the area explored is proportional to the attenuation of radiation by the tissue&#46;</p><p id="par0080" class="elsevierStylePara elsevierViewall">This is a safe technique&#44; since the dose of radiation used is minimal&#44; and very little inter and intra-observer variation has been demonstrated&#44; making it very useful for research&#46;</p><p id="par0085" class="elsevierStylePara elsevierViewall">In our study&#44; we quantified&#44; in grams&#58;<ul class="elsevierStyleList" id="lis0010"><li class="elsevierStyleListItem" id="lsti0035"><span class="elsevierStyleLabel">-</span><p id="par0090" class="elsevierStylePara elsevierViewall">Total lean mass &#40;TLM&#41;&#46;</p></li><li class="elsevierStyleListItem" id="lsti0040"><span class="elsevierStyleLabel">-</span><p id="par0095" class="elsevierStylePara elsevierViewall">Trunk lean mass &#40;TrLM&#41;&#46;</p></li><li class="elsevierStyleListItem" id="lsti0045"><span class="elsevierStyleLabel">-</span><p id="par0100" class="elsevierStylePara elsevierViewall">Leg lean mass &#40;LLM&#41;&#46;</p></li></ul></p><p id="par0105" class="elsevierStylePara elsevierViewall">The examination was performed using the Norland densitometer XR-800 TM WITH Illuminatus software version 4&#46;5&#46;0 &#40;Norland&#44; a CooperSurgical Company&#44; Fort Atkinson&#44; WI&#44; U&#46;S&#46;&#41;&#46; All densitometries were performed following standardized protocols provided by the manufacturer and described by Aguado et al&#46;<a class="elsevierStyleCrossRef" href="#bib0235"><span class="elsevierStyleSup">18</span></a></p><p id="par0110" class="elsevierStylePara elsevierViewall">All examinations were performed using the same equipment&#44; in the same laboratory by the same technician&#46;</p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0090">Evaluation of Lung Function</span><p id="par0115" class="elsevierStylePara elsevierViewall">All subjects underwent forced spirometry with a COSMED K4 b<span class="elsevierStyleSup">2</span> turbine spirometer&#44; after calibration of the flow measured using a calibration syringe certified by the <span class="elsevierStyleItalic">American Thoracic Society</span> &#40;ATS&#41;&#46; The spirometry study was performed according to the protocol recommended by the Spanish Society of Pulmonology and Thoracic Surgery &#40;SEPAR&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib0240"><span class="elsevierStyleSup">19</span></a> Absolute FVC and FEV<span class="elsevierStyleInf">1</span> values were measured in milliliters &#40;ml&#41;&#44; and peak expiratory flow &#40;PEF&#41; and forced expiratory flow between 25&#37; and 75&#37; of forced vital capacity &#40;FEF<span class="elsevierStyleInf">25&#37;&#8211;75&#37;</span>&#41; were measured in liters per second&#46;</p><p id="par0120" class="elsevierStylePara elsevierViewall">All tests were performed by the same technician&#44; in the same laboratory&#44; using the same equipment&#46;</p></span></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0095">Analysis</span><p id="par0125" class="elsevierStylePara elsevierViewall">The statistical analysis was performed using the SPSS 22&#46;0 and Statgraphics Centurion 17 package for Windows&#46;</p><p id="par0130" class="elsevierStylePara elsevierViewall">The arithmetic mean&#44; standard deviation&#44; and minimum and maximum values were obtained for men and women&#46; Differences in means of both sexes were evaluated using the t test for independent samples&#46;</p><p id="par0135" class="elsevierStylePara elsevierViewall">To explore linear associations between the spirometric variables and the lean mass variables&#44; principal components analysis on the correlation matrix was used to reduce dimensionality&#44; obtaining a 2-dimensional graphic that revealed the relationships between the variables&#44; so that the more acute the angle formed&#44; the greater the linear relationship&#46;</p><p id="par0140" class="elsevierStylePara elsevierViewall">Relationships between the different spirometric variables and the lean mass variables were analyzed using correlations&#46; Partial correlations were used&#44; adjusting for age and body mass index &#40;BMI&#41;&#44; to eliminate the possible effect of confounding factors &#40;age&#44; height and weight&#41;&#46;</p><p id="par0145" class="elsevierStylePara elsevierViewall">A multiple linear regression analysis was performed to determine if the lean mass variables could be considered as predictive factor for spirometric variables&#46;</p></span></span><span id="sec0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0100">Results</span><p id="par0150" class="elsevierStylePara elsevierViewall">Descriptive statistics of the muscle mass and lung function variables in men and women are shown in <a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a>&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><p id="par0155" class="elsevierStylePara elsevierViewall">All variables analyzed showed significant differences in mean values of both sexes&#44; except age and sex&#46; Means were higher in men&#44; as shown in <a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a>&#44; with statistically significant <span class="elsevierStyleItalic">p</span> values&#46;</p><p id="par0160" class="elsevierStylePara elsevierViewall">In the principal components analysis&#44; positive correlations between all spirometric variables and all lean mass variables were found in both sexes&#44; with the greatest correlation being observed for LLM &#40;<a class="elsevierStyleCrossRefs" href="#fig0005">Figs&#46; 1 and 2</a>&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0165" class="elsevierStylePara elsevierViewall">Partial correlations between lean mass and spirometric variables&#44; adjusting for age and BMI&#44; were positive and highly statistically significant in both women and men&#44; with higher coefficients in the latter &#40;<a class="elsevierStyleCrossRefs" href="#tbl0010">Tables 2 and 3</a>&#41;&#46;</p><elsevierMultimedia ident="tbl0010"></elsevierMultimedia><elsevierMultimedia ident="tbl0015"></elsevierMultimedia><p id="par0170" class="elsevierStylePara elsevierViewall">Variables showing higher correlation coefficients with FVC and with FEV<span class="elsevierStyleInf">1</span> were LLM in men and TrLM in women&#46;</p><p id="par0175" class="elsevierStylePara elsevierViewall">In the multiple linear regression analysis&#44; equations to predict spirometric variables according to age&#44; BMI and lean mass variables were obtained&#44; along with adjusted coefficients of determination &#40;<span class="elsevierStyleItalic">R</span><span class="elsevierStyleSup">2</span>&#41; &#40;<a class="elsevierStyleCrossRef" href="#tbl0020">Table 4</a>&#41;&#46;</p><elsevierMultimedia ident="tbl0020"></elsevierMultimedia><p id="par0180" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleItalic">R</span><span class="elsevierStyleSup">2</span> between lean mass and spirometric variables are greater in men&#46; The spirometric variable with the highest values was FEV<span class="elsevierStyleInf">1</span>&#44; followed by FVC and PEF&#44; in both men and women&#46; In men&#44; LLM is the variable that showed the highest <span class="elsevierStyleItalic">R</span><span class="elsevierStyleSup">2</span> with spirometric variables&#44; while in women&#44; it was TrLM&#46;</p><p id="par0185" class="elsevierStylePara elsevierViewall">All estimated regression coefficients in lean mass were positive and statistically significant &#40;<span class="elsevierStyleItalic">p</span>&#60;0&#46;05&#41;&#44; suggesting that the greater the amount of lean body mass&#44; the greater the absolute values obtained on spirometry&#46; The highest coefficients were for LLM in men and TrLM in women&#46;</p></span><span id="sec0045" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0105">Discussion and Conclusions</span><p id="par0190" class="elsevierStylePara elsevierViewall">The aim of this study was to establish the association between spirometric results and lean mass determined by DEXA in healthy individuals&#46; Variability in the spirometry values obtained in healthy individuals of similar characteristics have led some authors<a class="elsevierStyleCrossRefs" href="#bib0150"><span class="elsevierStyleSup">1&#44;2</span></a> to believe that factors other than sex&#44; age&#44; height&#44; and weight might determine results&#46; Determinants such as inherited genetic factors and the presence of certain vitamins in an individual&#39;s diet have been discussed&#46; The premise of this study is that one of the factors that might cause this variability could be muscle mass&#46; Other studies have attempted to establish the influence of the muscle component of the body on spirometric results in healthy individuals&#58;</p><p id="par0195" class="elsevierStylePara elsevierViewall">Cotes et al&#46;<a class="elsevierStyleCrossRef" href="#bib0160"><span class="elsevierStyleSup">3</span></a> found a significant association between the Fat-Free Mass Index &#40;FFMI&#41;&#44; in which lean mass is adjusted for subject height obtained from anthropometric measurements&#44; and the main spirometric parameters&#46; They used linear regression models to obtain reference equations that included FFMI&#44; and found that these equations were more accurate than those which included only sex&#44; age&#44; height&#44; and weight&#46;</p><p id="par0200" class="elsevierStylePara elsevierViewall">Mohamed et al&#46;<a class="elsevierStyleCrossRef" href="#bib0165"><span class="elsevierStyleSup">4</span></a> also measured a muscle mass parameter&#44; bone-free lean body mass &#40;BF-LBM&#41;&#44; using DEXA&#44; and&#44; like us&#44; found a significant positive association between that parameter and the main spirometric variables in a group of healthy Italian subjects&#46; The age range is similar&#44; but the series size is rather smaller than ours &#40;58 men and 60 women&#41;&#44; and the influence of regional lean mass variables was not studied&#46;</p><p id="par0205" class="elsevierStylePara elsevierViewall">More recently&#44; Lim et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib0170"><span class="elsevierStyleSup">5</span></a> in a study of elderly Korean individuals with no chronic respiratory diseases&#44; found a significant association between trunk and leg muscle measured by DEXA and the main spirometric parameters&#44; in both women and men&#46; Their results are similar to our findings&#44; although only elderly subjects of non-Caucasian origin were included&#46;</p><p id="par0215" class="elsevierStylePara elsevierViewall">Park et al&#46;<a class="elsevierStyleCrossRef" href="#bib0175"><span class="elsevierStyleSup">6</span></a> also conducted a study in Korean subjects&#44; but with a mean age of 46 years&#46; They found a significant correlation between lean body mass &#8211; measured in this case by bioelectric impedance &#8211; and spirometric parameters&#44; in both men and women&#46; However&#44; they did not obtain a sufficiently high <span class="elsevierStyleItalic">R</span><span class="elsevierStyleSup">2</span> to conclude that muscle mass was a factor that influenced breathing in the study individuals&#46;</p><p id="par0220" class="elsevierStylePara elsevierViewall">Mean values of all respiratory parameters are significantly higher among men than women&#46; The larger amount of total lean body mass in men might explain the difference in the spirometric results between both sexes&#44; taking into account that respiratory mechanical properties are basically the same in both&#46;<a class="elsevierStyleCrossRef" href="#bib0245"><span class="elsevierStyleSup">20</span></a> Mean amounts of lean body mass in the different body regions are also higher in men&#46; These results are in line with those of Aguado et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib0250"><span class="elsevierStyleSup">21</span></a> who determined total and regional lean mass by DEXA in a series of healthy individuals of both sexes&#44; grouped according to age&#46; These authors found consistently larger amounts of total and regional lean body mass in men&#46;</p><p id="par0225" class="elsevierStylePara elsevierViewall">One of the principal results of the study is the significant association of lean mass in the legs with the main spirometric parameters&#46; In men&#44; leg lean mass affected spirometric results even more than total lean mass or trunk lean mass&#44; where the major ventilatory muscles are located&#46; In the clinical setting&#44; Hillman et al&#46;<a class="elsevierStyleCrossRef" href="#bib0255"><span class="elsevierStyleSup">22</span></a> believe that muscle strength and muscle mass in the legs are a possible determinant of the efficacy of training programs for pulmonary rehabilitation&#46; They also observed that approximately 33&#37; of patients with COPD presented muscle dysfunction in the lower limbs&#44; even in the early stages of the disease&#46;</p><p id="par0230" class="elsevierStylePara elsevierViewall">While leg lean mass in women is also significantly associated with spirometric parameters&#44; this is not the variable that shows the greatest association&#46; Rather&#44; the amount of muscle mass in the trunk has most impact on spirometric results&#46; This difference between the sexes does not appear to be explained by differences in the regional distribution of lean mass&#44; since no significant differences in this distribution were revealed in the study&#46; In both sexes&#44; the amount of lean mass is greater in the trunk than in the legs&#44; and in similar proportions&#46; The explanation for this difference might be the predominantly thoracic breathing pattern in women&#46;</p><p id="par0235" class="elsevierStylePara elsevierViewall">The possible direct relationship between muscle mass and strength may explain the association between lean mass parameters and spirometric values&#46; This hypothesis is also supported by the fact that a significant association is also found between PEF values&#44; the spirometric parameter most dependent on expiratory muscle strength&#44; and lean mass values&#44; in both men and women&#46; In women&#44; PEF is most associated with trunk mean mass&#46; However&#44; some authors<a class="elsevierStyleCrossRefs" href="#bib0260"><span class="elsevierStyleSup">23&#44;24</span></a> found that strength does not depend exclusively on muscle mass&#44; and the relationship between these parameters is not linear&#46; The most widely used functional tests for measuring respiratory muscle strength are maximum inspiratory pressure &#40;MIP&#41; and maximum expiratory pressure &#40;MEP&#41;&#46; A further study&#44; evaluating the association between lean mass determined by DEXA and MIP and MEP values would help clarify this issue&#46; In this respect&#44; Costes et al&#46;<a class="elsevierStyleCrossRef" href="#bib0270"><span class="elsevierStyleSup">25</span></a> found in a study of elderly individuals of both sexes that trunk lean mass determined by DEXA predicts MIP values&#44; but only in women&#46; Hillman et al&#46;<a class="elsevierStyleCrossRef" href="#bib0255"><span class="elsevierStyleSup">22</span></a> also found an association between lean mass in the legs and muscle strength determined by dynamometry in COPD patients&#46;</p><p id="par0240" class="elsevierStylePara elsevierViewall">Another result from our study is that all lean mass variables have more effect on FEV<span class="elsevierStyleInf">1</span> than on the other spirometric parameters&#44; in both men and women&#46; The greater capacity of the expiratory muscles to generate strength may lead to a greater volume of air being expired in the first second of the forced spirometry maneuver&#46; A positive association is also seen between the amount of lean mass and FEF<span class="elsevierStyleInf">25&#37;&#8211;75&#37;</span>&#44; altered values of which suggest small airway obstruction&#44; and may point to the presence of early-stage obstructive disease&#46; This might mean that a lower mean muscle mass might be a factor in the appearance of obstructive spirometric patterns&#46; In this respect&#44; Minas et al&#46;<a class="elsevierStyleCrossRef" href="#bib0210"><span class="elsevierStyleSup">13</span></a> compared muscle mass measured by bioelectric impedance in smokers without COPD and in patients with COPD&#44; and found it to be significantly lower in the latter&#44; even in patients in mild stages of the disease&#46; The same authors studied a group of patients with asthma&#44; another of the most prevalent obstructive diseases&#46; They found that patients with severe treatment-resistant asthma had lower muscle mass measured by bioelectric impedance than those with milder forms of asthma&#44; suggesting that muscle mass may be used as a prognostic factor in these patients&#46;</p><p id="par0245" class="elsevierStylePara elsevierViewall">Another publication reports that up to one third of COPD patients had deteriorated muscle function in the lower limbs&#44; even in the early stages of the disease&#46;<a class="elsevierStyleCrossRef" href="#bib0275"><span class="elsevierStyleSup">26</span></a> However&#44; in our study&#44; we did not find a significant association between lean mass parameters and FEV<span class="elsevierStyleInf">1</span>&#47;FVC index in either sex&#46; We did not find&#44; then&#44; that lower lean mass was a factor for a lower FEV<span class="elsevierStyleInf">1</span>&#47;FVC index&#44; which would belie the idea that lower muscle mass might be associated with a greater tendency to develop obstructive spirometric patterns&#46;</p><p id="par0250" class="elsevierStylePara elsevierViewall">Spirometric values in healthy individuals are known to peak in the third decade of life&#44; in both men and women&#46; These values then gradually decline with age&#46;<a class="elsevierStyleCrossRef" href="#bib0280"><span class="elsevierStyleSup">27</span></a> The course of muscle mass is similar&#58; after reaching a peak&#44; it too declines progressively over the years&#46;<a class="elsevierStyleCrossRefs" href="#bib0285"><span class="elsevierStyleSup">28&#44;29</span></a> The association between lean mass and spirometric parameters might suggest that loss of muscle mass is one of the factors that might explain the age-related progressive decline in spirometric parameters&#44; as well as deterioration of the mechanical properties of the ribcage and loss of elasticity and distensibility of the alveoli and the airway&#46;</p><p id="par0255" class="elsevierStylePara elsevierViewall">In conclusion&#44; muscle mass has a significant influence on lung function in health individuals of both sexes&#44; but this influence is greater in men&#46;</p><p id="par0260" class="elsevierStylePara elsevierViewall">The amount of lean mass in the legs is the variable that shows closest association with all spirometric parameters in men&#44; while in women&#44; it is trunk lean mass&#46;</p><p id="par0265" class="elsevierStylePara elsevierViewall">In both sexes&#44; lean mass is mainly associated with FEV<span class="elsevierStyleInf">1</span> followed by FEV and PEF&#46; However&#44; it is not significantly related with the FEV<span class="elsevierStyleInf">1</span>&#47;FVC index&#46;</p></span><span id="sec0050" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0110">Conflict of Interests</span><p id="par0270" class="elsevierStylePara elsevierViewall">The authors state that they have no conflict of interests&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:10 [
        0 => array:3 [
          "identificador" => "xres858021"
          "titulo" => "Abstract"
          "secciones" => array:4 [
            0 => array:2 [
              "identificador" => "abst0005"
              "titulo" => "Introduction"
            ]
            1 => array:2 [
              "identificador" => "abst0010"
              "titulo" => "Methods"
            ]
            2 => array:2 [
              "identificador" => "abst0015"
              "titulo" => "Results"
            ]
            3 => array:2 [
              "identificador" => "abst0020"
              "titulo" => "Conclusions"
            ]
          ]
        ]
        1 => array:2 [
          "identificador" => "xpalclavsec852168"
          "titulo" => "Keywords"
        ]
        2 => array:3 [
          "identificador" => "xres858020"
          "titulo" => "Resumen"
          "secciones" => array:4 [
            0 => array:2 [
              "identificador" => "abst0025"
              "titulo" => "Introducci&#243;n"
            ]
            1 => array:2 [
              "identificador" => "abst0030"
              "titulo" => "M&#233;todos"
            ]
            2 => array:2 [
              "identificador" => "abst0035"
              "titulo" => "Resultados"
            ]
            3 => array:2 [
              "identificador" => "abst0040"
              "titulo" => "Conclusiones"
            ]
          ]
        ]
        3 => array:2 [
          "identificador" => "xpalclavsec852167"
          "titulo" => "Palabras clave"
        ]
        4 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Introduction"
        ]
        5 => array:3 [
          "identificador" => "sec0010"
          "titulo" => "Methods"
          "secciones" => array:3 [
            0 => array:2 [
              "identificador" => "sec0015"
              "titulo" => "Study Subjects"
            ]
            1 => array:3 [
              "identificador" => "sec0020"
              "titulo" => "Methods"
              "secciones" => array:2 [
                0 => array:2 [
                  "identificador" => "sec0025"
                  "titulo" => "Muscle Mass Assessment"
                ]
                1 => array:2 [
                  "identificador" => "sec0030"
                  "titulo" => "Evaluation of Lung Function"
                ]
              ]
            ]
            2 => array:2 [
              "identificador" => "sec0035"
              "titulo" => "Analysis"
            ]
          ]
        ]
        6 => array:2 [
          "identificador" => "sec0040"
          "titulo" => "Results"
        ]
        7 => array:2 [
          "identificador" => "sec0045"
          "titulo" => "Discussion and Conclusions"
        ]
        8 => array:2 [
          "identificador" => "sec0050"
          "titulo" => "Conflict of Interests"
        ]
        9 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2016-08-05"
    "fechaAceptado" => "2016-11-29"
    "PalabrasClave" => array:2 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec852168"
          "palabras" => array:4 [
            0 => "Fat-free soft tissue mass"
            1 => "Lean body mass"
            2 => "Dual energy X-ray absorptiometry"
            3 => "Spirometry"
          ]
        ]
      ]
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec852167"
          "palabras" => array:4 [
            0 => "Tejido blando no graso"
            1 => "Tejido magro"
            2 => "Absorciometr&#237;a dual fot&#243;nica de rayos X"
            3 => "Espirometr&#237;a"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "en" => array:3 [
        "titulo" => "Abstract"
        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Introduction</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Muscle mass maybe a determining factor in the variability of spirometry results in individuals of the same sex and age who have similar anthropometric characteristics&#46; The aim of this study was to determine the association between spirometric results from healthy individuals and their muscle mass assessed by dual energy X-ray absorptiometry &#40;DEXA&#41;&#46;</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Methods</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">A sample of 161 women and 144 men&#44; all healthy non-smokers&#44; was studied&#46; Ages ranged from18 to77<span class="elsevierStyleHsp" style=""></span>years&#46; For each subject&#44; spirometry results and total and regional lean mass values obtained by full body DEXA were recorded&#46; A descriptive analysis of the variables and a regression analysis were performed to study the relationship between spirometric variables and lean body mass&#44; correcting for age and body mass index &#40;BMI&#41;&#46;</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Results</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">In both sexes all muscle mass variables correlated positively and significantly with spirometric variables&#44; and to a greater extent in men&#46; After partial adjustment of correlations by age and BMI&#44; the factor which best explains the spirometric variables is the total lean body mass in men&#44; and trunk lean body mass in women&#46;</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Conclusions</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">In men&#44; muscle mass in the lower extremities is most closely associated with spirometric results&#46; In women&#44; it is the muscle mass of the trunk&#46; In both sexes muscle mass mainly affects FEV<span class="elsevierStyleInf">1</span>&#46;</p></span>"
        "secciones" => array:4 [
          0 => array:2 [
            "identificador" => "abst0005"
            "titulo" => "Introduction"
          ]
          1 => array:2 [
            "identificador" => "abst0010"
            "titulo" => "Methods"
          ]
          2 => array:2 [
            "identificador" => "abst0015"
            "titulo" => "Results"
          ]
          3 => array:2 [
            "identificador" => "abst0020"
            "titulo" => "Conclusions"
          ]
        ]
      ]
      "es" => array:3 [
        "titulo" => "Resumen"
        "resumen" => "<span id="abst0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Introducci&#243;n</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">La cantidad de masa muscular podr&#237;a ser un factor determinante que explicara la variabilidad de los resultados de la espirometr&#237;a en individuos del mismo sexo y edad y de caracter&#237;sticas antropom&#233;tricas similares&#46; El objetivo de este estudio es determinar si existe asociaci&#243;n entre los resultados espirom&#233;tricos de individuos sanos y su masa muscular estimada mediante absorciometr&#237;a de rayos X &#40;DEXA&#41;&#46;</p></span> <span id="abst0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">M&#233;todos</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Se estudi&#243; una muestra de 161 mujeres y 143 varones sanos&#44; no fumadores&#44; de 18 a 77<span class="elsevierStyleHsp" style=""></span>a&#241;os&#46; En cada sujeto se registraron los resultados de una espirometr&#237;a y los valores de la masa magra total y regional obtenidos mediante DEXA&#46; Se realiz&#243; un an&#225;lisis descriptivo de las variables y un an&#225;lisis de regresi&#243;n para estudiar las relaciones entre variables espirom&#233;tricas y masa magra&#44; corrigiendo los efectos que pudieran ejercer la edad y el &#237;ndice de masa corporal &#40;IMC&#41;&#46;</p></span> <span id="abst0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Resultados</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">En ambos sexos todas las variables de masa magra se correlacionan de forma positiva y significativa con las variables espirom&#233;tricas&#44; siendo estas relaciones mayores en los varones&#46; Al ajustar estas correlaciones de forma parcial por la edad y el IMC&#44; lo que mejor explica las variables espirom&#233;tricas es la masa magra en las extremidades inferiores en varones&#44; y la masa magra del tronco en mujeres&#46;</p></span> <span id="abst0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Conclusiones</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">En los varones&#44; la masa muscular en las extremidades inferiores es la que m&#225;s se asocia a los resultados espirom&#233;tricos&#46; En las mujeres es la masa muscular del tronco&#46; En ambos sexos la masa muscular influye principalmente sobre el volumen espiratorio forzado en el primer segundo &#40;FEV<span class="elsevierStyleInf">1</span>&#41;&#46;</p></span>"
        "secciones" => array:4 [
          0 => array:2 [
            "identificador" => "abst0025"
            "titulo" => "Introducci&#243;n"
          ]
          1 => array:2 [
            "identificador" => "abst0030"
            "titulo" => "M&#233;todos"
          ]
          2 => array:2 [
            "identificador" => "abst0035"
            "titulo" => "Resultados"
          ]
          3 => array:2 [
            "identificador" => "abst0040"
            "titulo" => "Conclusiones"
          ]
        ]
      ]
    ]
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0015">Please cite this article as&#58; Mart&#237;n Holguera R&#44; Turri&#243;n Nieves AI&#44; Rodr&#237;guez Torres R&#44; Alonso MC&#46; Asociaci&#243;n de la masa muscular determinada mediante DEXA con los resultados espirom&#233;tricos de individuos sanos&#46; Arch Bronconeumol&#46; 2017&#59;53&#58;375&#8211;380&#46;</p>"
      ]
    ]
    "multimedia" => array:6 [
      0 => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Fig&#46; 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 1152
            "Ancho" => 1578
            "Tamanyo" => 117729
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Principal component analysis in men with an overall explanation of 76&#46;07&#37; &#40;47&#46;1&#37; explains the first component and 28&#46;97&#37; the second&#41;&#46; FEV<span class="elsevierStyleInf">1</span>&#58; forced expiratory volume in 1<span class="elsevierStyleHsp" style=""></span>s&#59; FVC&#58; forced vital capacity&#59; BMI&#58; body mass index&#59; PEF&#58; peak expiratory flow&#59; LLM&#58; leg lean mass&#59; TLM&#58; total lean body mass&#59; TrLM&#58; trunk lean mass&#46;</p>"
        ]
      ]
      1 => array:7 [
        "identificador" => "fig0010"
        "etiqueta" => "Fig&#46; 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 1115
            "Ancho" => 1582
            "Tamanyo" => 120215
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Principal component analysis in women with an overall explanation of 73&#46;03&#37; &#40;46&#46;97&#37; explains the first component and 26&#46;05&#37; the second&#41;&#46; FEV<span class="elsevierStyleInf">1</span>&#58; Forced expiratory volume in 1<span class="elsevierStyleHsp" style=""></span>s&#59; FVC&#58; forced vital capacity&#59; BMI&#58; body mass index&#59; PEF&#58; peak expiratory flow&#59; LLM&#58; leg lean mass&#59; TLM&#58; total lean body mass&#59; TrLM&#58; trunk lean mass&#46;</p>"
        ]
      ]
      2 => array:8 [
        "identificador" => "tbl0005"
        "etiqueta" => "Table 1"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at1"
            "detalle" => "Table "
            "rol" => "short"
          ]
        ]
        "tabla" => array:3 [
          "leyenda" => "<p id="spar0060" class="elsevierStyleSimplePara elsevierViewall">FEF<span class="elsevierStyleInf">25&#37;&#8211;75&#37;</span>&#58; midexpiratory flow&#59; FEV<span class="elsevierStyleInf">1</span>&#58; forced expiratory volume in 1<span class="elsevierStyleHsp" style=""></span>s&#59; FVC&#58; forced vital capacity&#59; PEF&#58; peak expiratory flow&#59; LLM&#58; leg lean mass&#59; TLM&#58; total lean body mass&#59; TrLM&#58; trunk lean mass&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " rowspan="2" align="" valign="top" scope="col" style="border-bottom: 2px solid black"></th><th class="td" title="table-head  " align="left" valign="top" scope="col">Women&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col">Men&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " rowspan="2" align="center" valign="top" scope="col" style="border-bottom: 2px solid black"><span class="elsevierStyleItalic">p</span></th></tr><tr title="table-row"><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Mean&#44; Standard Deviation&#44; and Range&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Mean&#44; Standard Deviation&#44; and Range&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Age &#40;years&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">46&#46;4&#177;16&#46;8 &#40;18&#8211;75&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">43&#46;3&#177;16&#46;7 &#40;18&#8211;77&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Height &#40;cm&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">159&#46;9&#177;7 &#40;143&#8211;185&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">173&#46;2&#177;7&#46;5 &#40;154&#8211;190&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">&#42;&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Weight &#40;kg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">63&#46;8&#177;10&#46;1 &#40;44&#8211;97&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">80&#46;9&#177;12&#46;4 &#40;60&#8211;119&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">&#42;&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">BMI&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">25&#177;4&#46;3 &#40;16&#46;6&#8211;41&#46;9&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">26&#46;9&#177;3&#46;8 &#40;19&#46;7&#8211;40&#46;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">FVC &#40;ml&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3334&#46;2&#177;691&#46;5 &#40;1370&#8211;4720&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">4711&#46;5&#177;848&#46;3 &#40;2610&#8211;7000&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">&#42;&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">FEV1 &#40;ml&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">2830&#46;3&#177;614&#46;7 &#40;1150&#8211;4060&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3855&#46;9&#177;785&#46;3 &#40;1890&#8211;5920&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">&#42;&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">PEF&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">6212&#46;1&#177;1407&#46;9 &#40;2380&#8211;10<span class="elsevierStyleHsp" style=""></span>390&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">9066&#46;1&#177;1959&#46;7 &#40;3170&#8211;1&#46;3270&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">&#42;&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">FEF<span class="elsevierStyleInf">25&#37;&#8211;75&#37;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3226&#46;8&#177;943&#46;6 &#40;1040&#8211;6530&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">3985&#46;7&#177;1315&#46;6 &#40;1340&#8211;8660&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">&#42;&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">FEV1&#47;FVC&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">84&#177;5&#46;8 &#40;70&#8211;99&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">82&#177;5&#46;8 &#40;71&#8211;95&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">TLM &#40;kg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">34&#46;9&#177;44&#46;9 &#40;23&#46;1&#8211;49&#46;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">55&#46;2&#177;75&#46;1 &#40;40&#46;6&#8211;77&#46;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">&#42;&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">TrLM &#40;kg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">15&#46;5&#177;22&#46;1 &#40;10&#46;5&#8211;23&#46;2&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">25&#46;2&#177;38&#46;8 &#40;12&#46;2&#8211;38&#46;1&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">&#42;&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">LLM &#40;kg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">12&#46;7&#177;19&#46;8 &#40;7&#46;7&#8211;18&#46;8&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">19&#46;3&#177;30 &#40;13&#46;9&#8211;27&#46;3&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">&#42;&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab1449463.png"
              ]
            ]
          ]
          "notaPie" => array:1 [
            0 => array:3 [
              "identificador" => "tblfn0005"
              "etiqueta" => "&#42;&#42;"
              "nota" => "<p class="elsevierStyleNotepara" id="npar0005"><span class="elsevierStyleItalic">p</span>&#60;0&#46;01 is statistically significant&#46;</p>"
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">Descriptive Statistics of Study Participants&#46;</p>"
        ]
      ]
      3 => array:8 [
        "identificador" => "tbl0010"
        "etiqueta" => "Table 2"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at2"
            "detalle" => "Table "
            "rol" => "short"
          ]
        ]
        "tabla" => array:3 [
          "leyenda" => "<p id="spar0070" class="elsevierStyleSimplePara elsevierViewall">FEF<span class="elsevierStyleInf">25&#37;&#8211;75&#37;</span>&#58; midexpiratory flow&#59; FEV1&#58; forced expiratory volume in 1<span class="elsevierStyleHsp" style=""></span>s&#59; FVC&#58; forced vital capacity&#59; PEF&#58; peak expiratory flow&#59; LLM&#58; leg lean mass&#59; TLM&#58; total lean body mass&#59; TrLM&#58; trunk lean mass&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">FVC&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">FEV1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">PEF&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">FEF<span class="elsevierStyleInf">25&#37;&#8211;75&#37;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">FEV1&#47;FVC&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">TLM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;603<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">&#42;&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;583<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">&#42;&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;371<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">&#42;&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;310<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">&#42;&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#8722;0&#46;098&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">TrLM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;529<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">&#42;&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;477<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">&#42;&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;336<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">&#42;&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;219<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">&#42;&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#8722;0&#46;166&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">LLM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;607<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">&#42;&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;599<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">&#42;&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;351<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">&#42;&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;354<a class="elsevierStyleCrossRef" href="#tblfn0010"><span class="elsevierStyleSup">&#42;&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#8722;0&#46;052&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab1449462.png"
              ]
            ]
          ]
          "notaPie" => array:1 [
            0 => array:3 [
              "identificador" => "tblfn0010"
              "etiqueta" => "&#42;&#42;"
              "nota" => "<p class="elsevierStyleNotepara" id="npar0010"><span class="elsevierStyleItalic">p</span>&#60;0&#46;01 is highly statistically significant&#46;</p>"
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0065" class="elsevierStyleSimplePara elsevierViewall">Partial Correlation Coefficients Between Muscle Mass Variables and Spirometric Variables Adjusting for Age and Body Mass Index in Men&#46;</p>"
        ]
      ]
      4 => array:8 [
        "identificador" => "tbl0015"
        "etiqueta" => "Table 3"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at3"
            "detalle" => "Table "
            "rol" => "short"
          ]
        ]
        "tabla" => array:2 [
          "leyenda" => "<p id="spar0080" class="elsevierStyleSimplePara elsevierViewall">FEF<span class="elsevierStyleInf">25&#37;&#8211;75&#37;</span>&#58; midexpiratory flow&#59; FEV<span class="elsevierStyleInf">1</span>&#58; forced expiratory volume in 1<span class="elsevierStyleHsp" style=""></span>s&#59; FVC&#58; forced vital capacity&#59; PEF&#58; peak expiratory flow&#59; LLM&#58; leg lean mass&#59; TLM&#58; total lean body mass&#59; TrLM&#58; trunk lean mass&#46;</p><p id="spar0085" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleSup">&#42;</span><span class="elsevierStyleItalic">p</span>&#60;0&#46;05 is statistically significant&#46;</p><p id="spar0090" class="elsevierStyleSimplePara elsevierViewall"><span class="elsevierStyleSup">&#42;&#42;</span><span class="elsevierStyleItalic">p</span>&#60;0&#46;01 is highly statistically significant&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">FVC&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">FEV1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">PEF&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">FEF<span class="elsevierStyleInf">25&#37;&#8211;75&#37;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">FEV1&#47;FVC&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">TLM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;367<span class="elsevierStyleSup">&#42;&#42;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;341<span class="elsevierStyleSup">&#42;&#42;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;206<span class="elsevierStyleSup">&#42;&#42;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;165<span class="elsevierStyleSup">&#42;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#8722;0&#46;103&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">TrLM &#40;kg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;394<span class="elsevierStyleSup">&#42;&#42;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;373<span class="elsevierStyleSup">&#42;&#42;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;272<span class="elsevierStyleSup">&#42;&#42;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;183<span class="elsevierStyleSup">&#42;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#8722;0&#46;095&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">LLM &#40;kg&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;359<span class="elsevierStyleSup">&#42;&#42;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;337<span class="elsevierStyleSup">&#42;&#42;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;178<span class="elsevierStyleSup">&#42;&#42;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;167<span class="elsevierStyleSup">&#42;</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">&#8722;0&#46;094&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab1449461.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0075" class="elsevierStyleSimplePara elsevierViewall">Partial Correlation Coefficients Between Muscle Mass Variables and Spirometric Variables Adjusting for Age and Body Mass Index in Women&#46;</p>"
        ]
      ]
      5 => array:8 [
        "identificador" => "tbl0020"
        "etiqueta" => "Table 4"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at4"
            "detalle" => "Table "
            "rol" => "short"
          ]
        ]
        "tabla" => array:2 [
          "leyenda" => "<p id="spar0100" class="elsevierStyleSimplePara elsevierViewall">FEV<span class="elsevierStyleInf">1</span>&#58; forced expiratory volume in 1<span class="elsevierStyleHsp" style=""></span>s&#59; FVC&#58; forced vital capacity&#59; BMI&#58; body mass index&#59; PEF&#58; peak expiratory flow&#59; LLM&#58; leg lean mass&#59; TLM&#58; total lean mass&#59; TrLM&#58; trunk lean mass&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Equation&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Sex&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Adjusted <span class="elsevierStyleItalic">R</span><span class="elsevierStyleSup">2</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">FVC&#61;4159&#46;67&#8722;16&#46;4626&#42;Age&#8722;66&#46;2774&#42;BMI&#43;0&#46;157654&#42;LLM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">M&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">61&#46;66&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">FVC&#61;3496&#46;64&#8722;15&#46;6366&#42;Age&#8722;37&#46;1272&#42;BMI&#43;0&#46;113454&#42;LLM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">F&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">47&#46;80&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">FEV1&#61;3849&#46;83&#8722;23&#46;123&#42;Age&#8722;50&#46;7761&#42;BMI&#43;0&#46;122798&#42;LLM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">M&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">71&#46;71&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">FEV1&#61;3236&#46;55&#8722;19&#46;001&#42;Age&#8722;26&#46;2374&#42;BMI&#43;0&#46;0844262&#42;LLM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">F&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">57&#46;96&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">PEF&#61;7801&#46;62&#8722;40&#46;8775&#42;Age&#8722;55&#46;4911&#42;BMI&#43;0&#46;234124&#42;LLM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">M&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">34&#46;29&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">PEF&#61;6616&#46;24&#8722;34&#46;1297&#42;Age&#8722;22&#46;0113&#42;BMI&#43;0&#46;127834&#42;LLM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">F&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">27&#46;87&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">FVC&#61;4939&#46;19&#8722;28&#46;6842&#42;Age&#8722;55&#46;5342&#42;BMI&#43;0&#46;0996814&#42;TRLM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">M&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">56&#46;24&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">FVC&#61;3672&#46;79&#8722;20&#46;372&#42;Age&#8722;41&#46;0691&#42;BMI&#43;0&#46;101592&#42;TRLM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">F&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">49&#46;39&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">FEV1&#61;4543&#46;92&#8722;32&#46;8348&#42;Age&#8722;39&#46;124&#42;BMI&#43;0&#46;0710143&#42;TRLM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">M&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">65&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">FEV1&#61;3362&#46;43&#8722;22&#46;5101&#42;Age&#8722;29&#46;2664&#42;BMI&#43;0&#46;0760471&#42;TRLM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">F&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">59&#46;16&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">PEF&#61;8767&#46;04&#8722;58&#46;602&#42;Age&#8722;46&#46;8003&#42;BMI&#43;0&#46;162691&#42;TRLM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">M&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">33&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">PEF&#61;6296&#46;34&#8722;37&#46;9955&#42;Age&#8722;36&#46;0042&#42;BMI&#43;0&#46;159189&#42;TRLM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">F&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">31&#46;02&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">FVC&#61;4211&#46;3&#8722;20&#46;8774&#42;Age&#8722;74&#46;7347&#42;BMI&#43;0&#46;061934&#42;TLM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">M&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">61&#46;37&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">FVC&#61;3470&#46;12&#8722;17&#46;8657&#42;Age&#8722;42&#46;4918&#42;BMI&#43;0&#46;0487907&#42;TLM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">F&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">48&#46;16&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">FEV1&#61;3921&#46;89&#8722;26&#46;729&#42;Age&#8722;56&#46;2906&#42;BMI&#43;0&#46;047272&#42;TLM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">M&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">70&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">FEV1&#61;3230&#46;27&#8722;20&#46;7168&#42;Age&#8722;30&#46;0039&#42;BMI&#43;0&#46;0358316&#42;TLM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">F&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">58&#46;07&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">PEF&#61;7686&#46;54&#8722;46&#46;4255&#42;Age&#8722;74&#46;5144&#42;BMI&#43;0&#46;0978115&#42;TLM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">M&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">33&#46;36&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">PEF&#61;6383&#46;31&#8722;35&#46;7814&#42;Age&#8722;31&#46;457&#42;BMI&#43;0&#46;0621525&#42;TLM&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">F&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">28&#46;67&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab1449460.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0095" class="elsevierStyleSimplePara elsevierViewall">Regression Equations and Adjusted <span class="elsevierStyleItalic">R</span><span class="elsevierStyleSup">2</span> Values Obtained in the Multiple Linear Regression Analysis in Men and Women&#46;</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:29 [
            0 => array:3 [
              "identificador" => "bib0150"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Factors influencing lung function&#58; are the predicted values for spirometry reliable enough&#63;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "S&#46; Ostrowski"
                            1 => "W&#46; Barud"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "J Physiol Pharmacol"
                        "fecha" => "2006"
                        "volumen" => "57"
                        "numero" => "Suppl&#46; 4"
                        "paginaInicial" => "263"
                        "paginaFinal" => "271"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17072054"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0155"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Sources of variation in forced expiratory volume in one second and forced vital capacity"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "S&#46; Chinn"
                            1 => "D&#46; Jarvis"
                            2 => "C&#46; Svanes"
                            3 => "P&#46; Burney"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1183/09031936.06.00073105"
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur Respir J"
                        "fecha" => "2006"
                        "volumen" => "27"
                        "paginaInicial" => "767"
                        "paginaFinal" => "773"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16585084"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0160"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Body mass&#44; fat percentage&#44; and fat free mass as reference variables for lung function&#58; effects on terms for age and sex"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "J&#46;E&#46; Cotes"
                            1 => "D&#46;J&#46; Chinn"
                            2 => "J&#46;W&#46; Reed"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Thorax"
                        "fecha" => "2001"
                        "volumen" => "56"
                        "paginaInicial" => "839"
                        "paginaFinal" => "844"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11641507"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0165"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The impact of body-weight components on forced spirometry in healthy Italians"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "E&#46;I&#46; Mohamed"
                            1 => "C&#46; Maiolo"
                            2 => "L&#46; Iacopino"
                            3 => "M&#46; Pepe"
                            4 => "N&#46; di Daniele"
                            5 => "A&#46; de Lorenzo"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s004080000089"
                      "Revista" => array:6 [
                        "tituloSerie" => "Lung"
                        "fecha" => "2002"
                        "volumen" => "180"
                        "paginaInicial" => "149"
                        "paginaFinal" => "159"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12177729"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0170"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Association between body composition and pulmonary function in elderly people&#58; The Korean Longitudinal Study on Health and Aging"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "S&#46; Lim"
                            1 => "S&#46;Y&#46; Kwon"
                            2 => "J&#46;W&#46; Yoon"
                            3 => "S&#46;Y&#46; Kim"
                            4 => "S&#46;H&#46; Choi"
                            5 => "Y&#46;J&#46; Park"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Obesity &#40;Silver Spring&#41;"
                        "fecha" => "2011"
                        "volumen" => "19"
                        "paginaInicial" => "631"
                        "paginaFinal" => "638"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0175"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The effect of body composition on pulmonary function"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "J&#46;E&#46; Park"
                            1 => "J&#46;H&#46; Chung"
                            2 => "K&#46;H&#46; Lee"
                            3 => "K&#46;C&#46; Shin"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Tuberc Respir Dis &#40;Seoul&#41;"
                        "fecha" => "2012"
                        "volumen" => "72"
                        "paginaInicial" => "433"
                        "paginaFinal" => "440"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0180"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Dual-energy X-ray absorptiometry in the clinical evaluation of body composition and bone mineral density in patients with chronic obstructive pulmonary disease"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "M&#46;P&#46; Engelen"
                            1 => "A&#46;M&#46; Schols"
                            2 => "G&#46;A&#46; Heidendal"
                            3 => "E&#46;F&#46; Wouters"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Clin Nutr"
                        "fecha" => "1998"
                        "volumen" => "68"
                        "paginaInicial" => "1298"
                        "paginaFinal" => "1303"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9846862"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0185"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Dual-energy X-ray absorptiometry is the method of choice to assess body composition in COPD"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "A&#46; Miller"
                            1 => "B&#46;J&#46; Strauss"
                            2 => "S&#46; Mol"
                            3 => "A&#46; Kyoong"
                            4 => "P&#46;H&#46; Holmes"
                            5 => "P&#46; Finlay"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Respirology"
                        "fecha" => "2009"
                        "volumen" => "14"
                        "paginaInicial" => "411"
                        "paginaFinal" => "418"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19353776"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib0190"
              "etiqueta" => "9"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Bedside methods versus dual energy X-ray absorptiometry for body composition measurement in COPD"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "M&#46;C&#46; Steiner"
                            1 => "R&#46;L&#46; Barton"
                            2 => "S&#46;J&#46; Singh"
                            3 => "M&#46;D&#46; Morgan"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur Respir J"
                        "fecha" => "2002"
                        "volumen" => "19"
                        "paginaInicial" => "626"
                        "paginaFinal" => "631"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11998990"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib0195"
              "etiqueta" => "10"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Guidelines for the evaluation and treatment of muscle dysfunction in patients with chronic obstructive pulmonary disease"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "E&#46; Barreiro"
                            1 => "V&#46; Bustamante"
                            2 => "P&#46; Cejudo"
                            3 => "J&#46;B&#46; Galdiz"
                            4 => "J&#46; Gea"
                            5 => "P&#46; de Lucas"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.arbres.2015.04.011"
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Bronconeumol"
                        "fecha" => "2015"
                        "volumen" => "51"
                        "paginaInicial" => "384"
                        "paginaFinal" => "395"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26072153"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib0200"
              "etiqueta" => "11"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Muscle dysfunction in chronic obstructive pulmonary disease&#58; update on causes and biological findings"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "J&#46; Gea"
                            1 => "S&#46; Pascual"
                            2 => "C&#46; Casadevall"
                            3 => "M&#46; Orozco-Levi"
                            4 => "E&#46; Barreiro"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.3978/j.issn.2072-1439.2015.08.04"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Thorac Dis"
                        "fecha" => "2015"
                        "volumen" => "7"
                        "paginaInicial" => "E418"
                        "paginaFinal" => "E438"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26623119"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib0205"
              "etiqueta" => "12"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Lean mass predicts asthma better than fat mass among females"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "A&#46; Sood"
                            1 => "C&#46; Qualls"
                            2 => "R&#46; Li"
                            3 => "M&#46; Schuyler"
                            4 => "W&#46;S&#46; Beckett"
                            5 => "L&#46;J&#46; Smith"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1183/09031936.00193709"
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur Respir J"
                        "fecha" => "2011"
                        "volumen" => "37"
                        "paginaInicial" => "65"
                        "paginaFinal" => "71"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20525713"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib0210"
              "etiqueta" => "13"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Body composition in severe refractory asthma&#58; comparison with COPD patients and healthy smokers"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M&#46; Minas"
                            1 => "A&#46;I&#46; Papaioannou"
                            2 => "A&#46; Tsaroucha"
                            3 => "Z&#46; Daniil"
                            4 => "C&#46; Hatzoglou"
                            5 => "M&#46; Sgantzos"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1371/journal.pone.0013233"
                      "Revista" => array:5 [
                        "tituloSerie" => "PLoS ONE"
                        "fecha" => "2010"
                        "volumen" => "5"
                        "paginaInicial" => "e13233"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20949085"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib0215"
              "etiqueta" => "14"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Effect of physical training on fat-free mass in patients with chronic obstructive pulmonary disease &#40;COPD&#41;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "M&#46; Emtner"
                            1 => "R&#46; Hallin"
                            2 => "R&#46;H&#46; Arnardottir"
                            3 => "C&#46; Janson"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.3109/03009734.2014.990124"
                      "Revista" => array:6 [
                        "tituloSerie" => "Ups J Med Sci"
                        "fecha" => "2015"
                        "volumen" => "120"
                        "paginaInicial" => "52"
                        "paginaFinal" => "58"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25430624"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib0220"
              "etiqueta" => "15"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Body composition and health-related quality of life in patients with obstructive airways disease"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "R&#46; Shoup"
                            1 => "G&#46; Dalsky"
                            2 => "S&#46; Warner"
                            3 => "M&#46; Davies"
                            4 => "M&#46; Connors"
                            5 => "M&#46; Khan"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur Respir J"
                        "fecha" => "1997"
                        "volumen" => "10"
                        "paginaInicial" => "1576"
                        "paginaFinal" => "1580"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9230250"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib0225"
              "etiqueta" => "16"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Body mass and fat-free mass indices in COPD&#58; relation with variables expressing disease severity"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "E&#46; Ischaki"
                            1 => "G&#46; Papatheodorou"
                            2 => "E&#46; Gaki"
                            3 => "I&#46; Papa"
                            4 => "N&#46; Koulouris"
                            5 => "S&#46; Loukides"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1378/chest.06-2789"
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "2007"
                        "volumen" => "132"
                        "paginaInicial" => "164"
                        "paginaFinal" => "169"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17505043"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib0230"
              "etiqueta" => "17"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Body mass&#44; fat-free body mass&#44; and prognosis in patients with chronic obstructive pulmonary disease from a random population sample&#58; findings from the Copenhagen City Heart Study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "J&#46; Vestbo"
                            1 => "E&#46; Prescott"
                            2 => "T&#46; Almdal"
                            3 => "M&#46; Dahl"
                            4 => "B&#46;G&#46; Nordestgaard"
                            5 => "T&#46; Andersen"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1164/rccm.200506-969OC"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Respir Crit Care Med"
                        "fecha" => "2006"
                        "volumen" => "173"
                        "paginaInicial" => "79"
                        "paginaFinal" => "83"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16368793"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib0235"
              "etiqueta" => "18"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "An evaluation of patterns of change in total and regional body fat mass in healthy Spanish subjects using dual-energy X-ray absorptiometry &#40;DXA&#41;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "S&#46;A&#46; Aguado Henche"
                            1 => "R&#46;R&#46; Torres"
                            2 => "L&#46;G&#46; Pellico"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1038/sj.ejcn.1602883"
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur J Clin Nutr"
                        "fecha" => "2008"
                        "volumen" => "62"
                        "paginaInicial" => "1440"
                        "paginaFinal" => "1448"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17717537"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib0240"
              "etiqueta" => "19"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Recomendaciones SEPAR en espirometr&#237;a forzada"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "J&#46; Sanchis"
                            1 => "P&#46; Casan Clar&#225;"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:3 [
                        "fecha" => "1998"
                        "editorial" => "Respira"
                        "editorialLocalizacion" => "Barcelona"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib0245"
              "etiqueta" => "20"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Sex and age differences in pulmonary mechanics in normal nonsmoking subjects"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "G&#46;J&#46; Gibson"
                            1 => "N&#46;B&#46; Pride"
                            2 => "C&#46; O&#8217;cain"
                            3 => "R&#46; Quagliato"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Appl Physiol"
                        "fecha" => "1976"
                        "volumen" => "41"
                        "paginaInicial" => "20"
                        "paginaFinal" => "25"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/972127"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bib0250"
              "etiqueta" => "21"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "An evaluation of lean body mass in the Spanish Population using X-ray absoptiometry &#40;DXA&#41;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "S&#46;S&#46; Aguado Henche"
                            1 => "R&#46; Rodr&#237;guez Torres"
                            2 => "L&#46; G&#243;mez Pellico"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Int J Body Compos Res"
                        "fecha" => "2006"
                        "volumen" => "2"
                        "paginaInicial" => "67"
                        "paginaFinal" => "74"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            21 => array:3 [
              "identificador" => "bib0255"
              "etiqueta" => "22"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Relationship between body composition&#44; peripheral muscle strength and functional exercise capacity in patients with severe chronic obstructive pulmonary disease"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "C&#46;M&#46; Hillman"
                            1 => "E&#46;L&#46; Heinecke"
                            2 => "J&#46;W&#46; Hii"
                            3 => "N&#46;M&#46; Cecins"
                            4 => "S&#46;C&#46; Jenkins"
                            5 => "P&#46;R&#46; Eastwood"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/j.1445-5994.2012.02771.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "Intern Med J"
                        "fecha" => "2012"
                        "volumen" => "42"
                        "paginaInicial" => "578"
                        "paginaFinal" => "581"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22616963"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            22 => array:3 [
              "identificador" => "bib0260"
              "etiqueta" => "23"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The loss of skeletal muscle strength&#44; mass&#44; and quality in older adults&#58; the health&#44; aging and body composition study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "B&#46;H&#46; Goodpaster"
                            1 => "S&#46;W&#46; Park"
                            2 => "T&#46;B&#46; Harris"
                            3 => "S&#46;B&#46; Kritchevsky"
                            4 => "M&#46; Nevitt"
                            5 => "A&#46;V&#46; Schwartz"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Gerontol A Biol Sci Med Sci"
                        "fecha" => "2006"
                        "volumen" => "61"
                        "paginaInicial" => "1059"
                        "paginaFinal" => "1064"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17077199"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            23 => array:3 [
              "identificador" => "bib0265"
              "etiqueta" => "24"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Loss of skeletal muscle mass in aging&#58; examining the relationship of starvation&#44; sarcopenia and cachexia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "D&#46;R&#46; Thomas"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.clnu.2007.03.008"
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Nutr"
                        "fecha" => "2007"
                        "volumen" => "26"
                        "paginaInicial" => "389"
                        "paginaFinal" => "399"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17499396"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            24 => array:3 [
              "identificador" => "bib0270"
              "etiqueta" => "25"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Identification and comparison of the predictors of maximal inspiratory force and handgrip in a healthy elderly population&#46; The proof study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "F&#46; Costes"
                            1 => "S&#46; Celle"
                            2 => "M&#46; Garet"
                            3 => "M&#46; Kossovsky"
                            4 => "F&#46; Roche"
                            5 => "J&#46;C&#46; Barthelemy"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.clnu.2015.07.016"
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Nutr"
                        "fecha" => "2016"
                        "volumen" => "35"
                        "paginaInicial" => "963"
                        "paginaFinal" => "967"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26233802"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            25 => array:3 [
              "identificador" => "bib0275"
              "etiqueta" => "26"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The prevalence of quadriceps weakness in COPD and the relationship with disease severity"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "J&#46;M&#46; Seymour"
                            1 => "M&#46;A&#46; Spruit"
                            2 => "N&#46;S&#46; Hopkinson"
                            3 => "S&#46;A&#46; Natanek"
                            4 => "W&#46;D&#46; Man"
                            5 => "A&#46; Jackson"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1183/09031936.00104909"
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur Respir J"
                        "fecha" => "2010"
                        "volumen" => "36"
                        "paginaInicial" => "81"
                        "paginaFinal" => "88"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19897554"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            26 => array:3 [
              "identificador" => "bib0280"
              "etiqueta" => "27"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Aging and the respiratory system"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "A&#46; Rossi"
                            1 => "A&#46; Ganassini"
                            2 => "C&#46; Tantucci"
                            3 => "V&#46; Grassi"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Aging &#40;Milano&#41;"
                        "fecha" => "1996"
                        "volumen" => "8"
                        "paginaInicial" => "143"
                        "paginaFinal" => "161"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            27 => array:3 [
              "identificador" => "bib0285"
              "etiqueta" => "28"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Age-associated changes in skeletal muscles and their effect on mobility&#58; an operational diagnosis of sarcopenia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "F&#46; Lauretani"
                            1 => "C&#46;R&#46; Russo"
                            2 => "S&#46; Bandinelli"
                            3 => "B&#46; Bartali"
                            4 => "C&#46; Cavazzini"
                            5 => "A&#46; di Iorio"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J Appl Physiol &#40;1985&#41;"
                        "fecha" => "2003"
                        "volumen" => "95"
                        "paginaInicial" => "1851"
                        "paginaFinal" => "1860"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            28 => array:3 [
              "identificador" => "bib0290"
              "etiqueta" => "29"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Age adjustment of body composition"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "S&#46;S&#46; Aguado Henche"
                            1 => "R&#46; Rodr&#237;guez Torres"
                            2 => "L&#46; G&#243;mez Pellico"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Res Adv Clin Nutr"
                        "fecha" => "2009"
                        "volumen" => "1"
                        "paginaInicial" => "1"
                        "paginaFinal" => "18"
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/15792129/0000005300000007/v1_201706290145/S1579212917301751/v1_201706290145/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "9374"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Original Articles"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/15792129/0000005300000007/v1_201706290145/S1579212917301751/v1_201706290145/en/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212917301751?idApp=UINPBA00003Z"
]
Article information
ISSN: 15792129
Original language: English
The statistics are updated each day
Year/Month Html Pdf Total
2024 November 11 8 19
2024 October 46 24 70
2024 September 49 21 70
2024 August 64 58 122
2024 July 111 33 144
2024 June 70 38 108
2024 May 102 31 133
2024 April 58 33 91
2024 March 58 21 79
2024 February 37 21 58
2023 March 16 3 19
2023 February 58 26 84
2023 January 35 35 70
2022 December 80 23 103
2022 November 75 26 101
2022 October 133 42 175
2022 September 50 26 76
2022 August 93 45 138
2022 July 89 58 147
2022 June 45 40 85
2022 May 57 39 96
2022 April 61 36 97
2022 March 68 41 109
2022 February 48 25 73
2022 January 39 35 74
2021 December 40 34 74
2021 November 37 43 80
2021 October 63 41 104
2021 September 43 40 83
2021 August 31 40 71
2021 July 36 28 64
2021 June 50 34 84
2021 May 40 44 84
2021 April 85 82 167
2021 March 60 28 88
2021 February 33 20 53
2021 January 31 14 45
2020 December 47 22 69
2020 November 27 15 42
2020 October 35 34 69
2020 September 37 10 47
2020 August 26 12 38
2020 July 31 21 52
2020 June 27 11 38
2020 May 40 13 53
2020 April 44 22 66
2020 March 30 16 46
2020 February 29 17 46
2020 January 46 18 64
2019 December 39 19 58
2019 November 41 19 60
2019 October 32 19 51
2019 September 19 18 37
2019 August 27 20 47
2019 July 32 16 48
2019 June 40 12 52
2019 May 33 24 57
2019 April 40 47 87
2019 March 21 31 52
2019 February 26 14 40
2019 January 26 25 51
2018 December 23 16 39
2018 November 45 28 73
2018 October 41 19 60
2018 September 20 13 33
2018 May 10 0 10
2018 April 19 4 23
2018 March 27 11 38
2018 February 33 9 42
2018 January 18 8 26
2017 December 42 8 50
2017 November 26 9 35
2017 October 27 13 40
2017 September 0 1 1
Show all

Follow this link to access the full text of the article

Archivos de Bronconeumología

Are you a health professional able to prescribe or dispense drugs?