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Ref&#46; 451-514H0 Cordis<span class="elsevierStyleSup">&#174;</span>&#41;&#46; Due to the characteristics of the sealant&#44; a safety margin between the distal tip of the catheter and the bronchoscope lens was maintained&#46; Immediately after applying the bronchial sealant&#44; complete closure of the fistula was confirmed &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>c&#41;&#44; the bronchoscope was withdrawn together with the angioplasty catheter placed in the working channel to avoid any sealant remnants entering the interior of the working channel and damaging the equipment during withdrawal&#46; The distal end of the catheter was then closed to avoid any sealant remnant entering the working channel&#46; Five days after the application of Glubran<span class="elsevierStyleSup">&#174;</span> 2&#44; correct closure of the fistula was confirmed in a second endoscopic procedure&#59; the patient had improved clinically with progressive resolution of the subcutaneous emphysema&#46; The patient was followed up as an outpatient&#44; and a follow-up chest computed tomography was performed 6 months after surgery&#44; confirming clinical stability and complete resolution of the subcutaneous emphysema &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>d&#41;&#44; with no recurrence or other serious long-term complications&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">The physical and chemical properties of cyanoacrylate derivatives were described in 1959 by Coover et al&#46;<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">3</span></a> Methyl-2-cyanoacrylate was the first derivative used as surgical glue&#46; Differences in polymerization speed depend on chain length&#58; short-chain cyanoacrylates are faster&#44; but they also cause greater cytotoxicity and inflammatory reactions&#46; Currently&#44; long-chain cyanoacrylates &#40;butyl and octyl-cyanoacrylate&#41; are more commonly used as surgical sealants in different medical and surgical areas&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">The use of endobronchial valves<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">4</span></a> and other biological materials&#44; such as stromal cell preparations&#44;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">5</span></a> have been described as possible treatments for bronchopleural fistula&#46; With regard to sealants&#44; many materials and devices offering similar sealing results have been used&#44; although no comparative studies have been published on the use of different products&#46; Glubran<span class="elsevierStyleSup">&#174;</span> 2 is a new cyanoacrylate derivative that demonstrates excellent capacity for joining biological material&#46; The polymerized layer is highly resistant to rupture&#44; and polymerization time is slow&#46; In our patient&#44; BPF was closed with the use of cyanoacrylate and the air leak was controlled in a single endoscopy procedure&#44; placement of the material was easy&#44; and there were no complications&#46; In our experience&#44; the use of Glubran<span class="elsevierStyleSup">&#174;</span> 2 for endoscopic sealing of BPF was a feasible&#44; safe procedure&#44; offering immediate closure with no subsequent complications&#46;</p></span>"
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                    0 => array:2 [
                      "titulo" => "Bronchopleural fistulas&#58; an overview of the problem with special focus on endoscopic management"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
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                      "doi" => "10.1378/chest.128.6.3955"
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                        "fecha" => "2005"
                        "volumen" => "128"
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                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16354867"
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              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "&#191;Es &#250;til el tratamiento endosc&#243;pico de las f&#237;stulas bronquiales&#63;"
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                        0 => array:2 [
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                            3 => "R&#46; Laporta"
                            4 => "P&#46; Usetti"
                            5 => "P&#46; G&#225;mez"
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                        "paginaFinal" => "398"
                        "link" => array:1 [
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              "identificador" => "bib0040"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
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                    0 => array:2 [
                      "titulo" => "A comparison of a cyanoacrylate glue &#40;Glubran<span class="elsevierStyleSup">&#174;</span>&#41; vs fibrin sealant &#40;Tisseel<span class="elsevierStyleSup">&#174;</span>&#41; in experimental models of partial pulmonary resection and lung incision in rabbits"
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                        "volumen" => "23"
                        "paginaInicial" => "40"
                        "paginaFinal" => "47"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20233004"
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Scientific Letter
A New Cyanoacrylate Used as Bronchial Sealant in the Endoscopic Treatment of Bronchopleural Fistula
Utilización de un nuevo cianoacrilato como sellante bronquial en el tratamiento endoscópico de la fístula broncopleural
Sonia Cepedaa, Virginia Pajaresb,
Corresponding author
vpajares@santpau.cat

Corresponding author.
, Juan Carlos Trujillo-Reyesc, Alfons Torregob
a Servicio de Neumología, Hospital Universitario Dr. Peset, Valencia, Spain
b Servicio de Neumología, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
c Servicio de Cirugía Torácica, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">A bronchopleural fisutal is a comunication between the pleural space and the bronchial tree&#46; The most common cause of BPF is dehiscence of the surgical suture after lung resection&#44; which happens between in about 0&#46;8&#37; and 15&#37; of cases&#46; Therapeutic options are limited and depend&#44; among other factors&#44; on the size and site of the fistula&#46; Endoscopic treatment is a feasible therapeutic option&#44; particularly in BFP measuring &#60;5<span class="elsevierStyleHsp" style=""></span>mm&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a> Good final outcomes of BPF closure with Histoacryl<span class="elsevierStyleSup">&#174;</span> &#40;<span class="elsevierStyleItalic">N</span>-butyl-2-cyanoacrylate&#41; in respiratory endoscopy have been reported&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">2</span></a> However&#44; in practice&#44; the rapid polymerization of <span class="elsevierStyleItalic">N</span>-butyl-2-cyanoacrylate makes management and endoscopic placement difficult&#46; Other cyanoacrylates that polymerize at a different rate and at different temperatures are available&#44; and these may be easier to use with an endoscope&#46; No comparative studies have been published on the use of other cyanoacrylates&#44; such as Glubran<span class="elsevierStyleSup">&#174;</span> 2 &#40;<span class="elsevierStyleItalic">N</span>-butyl-2-cyanoacrylate&#43;metacryloxisulfolane&#41;&#44; as synthetic surgical sealants&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">We report the case of an 80-year-old man&#44; active smoker&#44; COPD&#44; GOLD B&#44; who underwent left posterolateral thoracotomy with lobectomy of the left upper lobe &#40;LUL&#41; and systemic lymph node resection&#44; with a diagnosis of squamous lung cancer&#44; stage pT2aN0M0&#46; Two weeks after the intervention&#44; the patient presented progressive subcutaneous and mediastinal emphysema&#44; with significant facial edema&#44; but no upper airway compromise &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>a&#41;&#46; During the endoscopic examination with flexible bronchoscope&#44; a 3<span class="elsevierStyleHsp" style=""></span>mm fistula was observed in the LUL lobectomy stump wound &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>b&#41;&#46; In view of the endoscopic findings&#44; persistent air leak&#44; and worsening subcutaneous emphysema&#44; the fistula was sealed using cyanoacrylate&#44; as follows&#58; 1<span class="elsevierStyleHsp" style=""></span>ml <span class="elsevierStyleItalic">N</span>-butyl-2-cyanoacrylate&#43;metacryloxisulfolane &#40;Glubran<span class="elsevierStyleSup">&#174;</span> 2 Ref&#46;G-NB-2&#44; GEM srl&#44; Italy&#41;&#44; applied using a syringe via a 5 Fr angioplasty catheter &#40;Angiographic Cathether Tempo<span class="elsevierStyleSup">&#174;</span> Vertebral &#91;VERT&#93; Ref&#46; 451-514H0 Cordis<span class="elsevierStyleSup">&#174;</span>&#41;&#46; Due to the characteristics of the sealant&#44; a safety margin between the distal tip of the catheter and the bronchoscope lens was maintained&#46; Immediately after applying the bronchial sealant&#44; complete closure of the fistula was confirmed &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>c&#41;&#44; the bronchoscope was withdrawn together with the angioplasty catheter placed in the working channel to avoid any sealant remnants entering the interior of the working channel and damaging the equipment during withdrawal&#46; The distal end of the catheter was then closed to avoid any sealant remnant entering the working channel&#46; Five days after the application of Glubran<span class="elsevierStyleSup">&#174;</span> 2&#44; correct closure of the fistula was confirmed in a second endoscopic procedure&#59; the patient had improved clinically with progressive resolution of the subcutaneous emphysema&#46; The patient was followed up as an outpatient&#44; and a follow-up chest computed tomography was performed 6 months after surgery&#44; confirming clinical stability and complete resolution of the subcutaneous emphysema &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>d&#41;&#44; with no recurrence or other serious long-term complications&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">The physical and chemical properties of cyanoacrylate derivatives were described in 1959 by Coover et al&#46;<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">3</span></a> Methyl-2-cyanoacrylate was the first derivative used as surgical glue&#46; Differences in polymerization speed depend on chain length&#58; short-chain cyanoacrylates are faster&#44; but they also cause greater cytotoxicity and inflammatory reactions&#46; Currently&#44; long-chain cyanoacrylates &#40;butyl and octyl-cyanoacrylate&#41; are more commonly used as surgical sealants in different medical and surgical areas&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">The use of endobronchial valves<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">4</span></a> and other biological materials&#44; such as stromal cell preparations&#44;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">5</span></a> have been described as possible treatments for bronchopleural fistula&#46; With regard to sealants&#44; many materials and devices offering similar sealing results have been used&#44; although no comparative studies have been published on the use of different products&#46; Glubran<span class="elsevierStyleSup">&#174;</span> 2 is a new cyanoacrylate derivative that demonstrates excellent capacity for joining biological material&#46; The polymerized layer is highly resistant to rupture&#44; and polymerization time is slow&#46; In our patient&#44; BPF was closed with the use of cyanoacrylate and the air leak was controlled in a single endoscopy procedure&#44; placement of the material was easy&#44; and there were no complications&#46; In our experience&#44; the use of Glubran<span class="elsevierStyleSup">&#174;</span> 2 for endoscopic sealing of BPF was a feasible&#44; safe procedure&#44; offering immediate closure with no subsequent complications&#46;</p></span>"
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                      "titulo" => "Bronchopleural fistulas&#58; an overview of the problem with special focus on endoscopic management"
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                          "autores" => array:2 [
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                        "volumen" => "18"
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Article information
ISSN: 15792129
Original language: English
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2021 October 51 64 115
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2021 August 39 39 78
2021 July 35 17 52
2021 June 54 38 92
2021 May 66 34 100
2021 April 147 86 233
2021 March 75 27 102
2021 February 44 30 74
2021 January 36 11 47
2020 December 36 11 47
2020 November 39 25 64
2020 October 59 24 83
2020 September 46 18 64
2020 August 32 20 52
2020 July 44 25 69
2020 June 41 12 53
2020 May 42 15 57
2020 April 50 25 75
2020 March 26 12 38
2020 February 52 25 77
2020 January 52 19 71
2019 December 57 28 85
2019 November 75 31 106
2019 October 25 14 39
2019 September 32 22 54
2019 August 43 21 64
2019 July 37 25 62
2019 June 43 16 59
2019 May 45 31 76
2019 April 36 32 68
2019 March 36 25 61
2019 February 27 19 46
2019 January 18 13 31
2018 December 23 16 39
2018 November 73 25 98
2018 October 59 21 80
2018 September 38 8 46
2018 May 16 0 16
2018 April 15 6 21
2018 March 25 6 31
2018 February 33 10 43
2018 January 86 6 92
2017 December 84 5 89
2017 November 31 11 42
2017 October 20 10 30
2017 September 17 6 23
2017 August 25 23 48
2017 July 22 12 34
2017 June 28 16 44
2017 May 2 1 3
2017 April 0 0 0
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