Clinical Image
A Case of Angioinvasive Aspergillosis
Un caso de aspergilosis angioinvasiva
Read
4823
Timeswas read the article
1624
Total PDF
3199
Total HTML
Share statistics
array:24 [ "pii" => "S1579212916303226" "issn" => "15792129" "doi" => "10.1016/j.arbr.2016.11.024" "estado" => "S300" "fechaPublicacion" => "2017-05-01" "aid" => "1475" "copyright" => "SEPAR" "copyrightAnyo" => "2016" "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Arch Bronconeumol. 2017;53:273" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1458 "formatos" => array:3 [ "EPUB" => 139 "HTML" => 1038 "PDF" => 281 ] ] "Traduccion" => array:1 [ "es" => array:19 [ "pii" => "S0300289616302587" "issn" => "03002896" "doi" => "10.1016/j.arbres.2016.09.013" "estado" => "S300" "fechaPublicacion" => "2017-05-01" "aid" => "1475" "copyright" => "SEPAR" "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Arch Bronconeumol. 2017;53:273" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 2244 "formatos" => array:3 [ "EPUB" => 117 "HTML" => 1569 "PDF" => 558 ] ] "es" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Imagen clínica</span>" "titulo" => "Un caso de aspergilosis angioinvasiva" "tienePdf" => "es" "tieneTextoCompleto" => "es" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "273" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "A Case of Angioinvasive Aspergillosis" ] ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figura 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 596 "Ancho" => 1400 "Tamanyo" => 112026 ] ] "descripcion" => array:1 [ "es" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">A) La TC inicial muestra nódulos con bordes mal definidos (flecha) predominantes en ambos lóbulos superiores. B) La TC de seguimiento, practicada 3 semanas después de iniciarse el tratamiento muestra cavitación de los nódulos previamente observados.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Víctor Vázquez Sánchez, Armando Gozalo García, Fermín Sáez Garmendia" "autores" => array:3 [ 0 => array:2 [ "nombre" => "Víctor" "apellidos" => "Vázquez Sánchez" ] 1 => array:2 [ "nombre" => "Armando" "apellidos" => "Gozalo García" ] 2 => array:2 [ "nombre" => "Fermín" "apellidos" => "Sáez Garmendia" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S1579212916303226" "doi" => "10.1016/j.arbr.2016.11.024" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212916303226?idApp=UINPBA00003Z" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289616302587?idApp=UINPBA00003Z" "url" => "/03002896/0000005300000005/v1_201704280943/S0300289616302587/v1_201704280943/es/main.assets" ] ] "itemSiguiente" => array:19 [ "pii" => "S1579212917300927" "issn" => "15792129" "doi" => "10.1016/j.arbr.2017.03.014" "estado" => "S300" "fechaPublicacion" => "2017-05-01" "aid" => "1489" "copyright" => "SEPAR" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "crp" "cita" => "Arch Bronconeumol. 2017;53:274-6" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1928 "formatos" => array:3 [ "EPUB" => 134 "HTML" => 1338 "PDF" => 456 ] ] "en" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Scientific Letter</span>" "titulo" => "<span class="elsevierStyleItalic">Actinomyces Meyeri</span> Empyema" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "274" "paginaFinal" => "276" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Empiema por <span class="elsevierStyleItalic">Actinomyces meyeri</span>" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Lucía Ferreiro, María Luisa Pérez del Molino, Carlos Rábade, Luis Valdés" "autores" => array:4 [ 0 => array:2 [ "nombre" => "Lucía" "apellidos" => "Ferreiro" ] 1 => array:2 [ "nombre" => "María Luisa" "apellidos" => "Pérez del Molino" ] 2 => array:2 [ "nombre" => "Carlos" "apellidos" => "Rábade" ] 3 => array:2 [ "nombre" => "Luis" "apellidos" => "Valdés" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0300289616302721" "doi" => "10.1016/j.arbres.2016.09.016" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289616302721?idApp=UINPBA00003Z" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212917300927?idApp=UINPBA00003Z" "url" => "/15792129/0000005300000005/v1_201704280925/S1579212917300927/v1_201704280925/en/main.assets" ] "itemAnterior" => array:19 [ "pii" => "S1579212917300903" "issn" => "15792129" "doi" => "10.1016/j.arbr.2017.03.012" "estado" => "S300" "fechaPublicacion" => "2017-05-01" "aid" => "1487" "copyright" => "SEPAR" "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Arch Bronconeumol. 2017;53:272" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1415 "formatos" => array:3 [ "EPUB" => 133 "HTML" => 950 "PDF" => 332 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Clinical Image</span>" "titulo" => "Foreign Body Aspiration During Inhaled Bronchodilator Administration" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "272" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Aspiración de cuerpo extraño en relación con la aplicación de broncodilatador inhalado" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1001 "Ancho" => 2461 "Tamanyo" => 260092 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Posteroanterior and lateral chest radiograph, showing the foreign body (LED light bulb) lodged in the right main bronchus.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "M. Teresa Gómez Hernández, Nuria M. Novoa, Marcelo F. Jiménez" "autores" => array:3 [ 0 => array:2 [ "nombre" => "M. Teresa" "apellidos" => "Gómez Hernández" ] 1 => array:2 [ "nombre" => "Nuria M." "apellidos" => "Novoa" ] 2 => array:2 [ "nombre" => "Marcelo F." "apellidos" => "Jiménez" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0300289616302708" "doi" => "10.1016/j.arbres.2016.11.001" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289616302708?idApp=UINPBA00003Z" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212917300903?idApp=UINPBA00003Z" "url" => "/15792129/0000005300000005/v1_201704280925/S1579212917300903/v1_201704280925/en/main.assets" ] "en" => array:14 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Clinical Image</span>" "titulo" => "A Case of Angioinvasive Aspergillosis" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "273" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Víctor Vázquez Sánchez, Armando Gózalo García, Fermín Sáez Garmendia" "autores" => array:3 [ 0 => array:4 [ "nombre" => "Víctor" "apellidos" => "Vázquez Sánchez" "email" => array:1 [ 0 => "victor_becedillas@hotmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "Armando" "apellidos" => "Gózalo García" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "Fermín" "apellidos" => "Sáez Garmendia" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Radiodiagnóstico, Hospital Nuestra Señora de la Candelaria, Santa Cruz de Tenerife, Tenerife, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Sección de Radiología Pediátrica, Hospital de Cruces, Barakaldo, Vizcaya, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Un caso de aspergilosis angioinvasiva" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 642 "Ancho" => 1500 "Tamanyo" => 116648 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Initial CT scan (left image) showing ill-defined nodules (arrow) with upper lobe predominance. Follow-up CT scan (right image) performed 3 weeks after starting treatment showing cavitation of known nodules.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">We present the case of a 13-year-old female with febrile neutropenia in the context of medullary aplasia secondary to chemotherapy treatment for acute lymphocytic leukemia. An opportunistic infection was suspected and Galactomannan test was performed with a positive result.</p><p id="par0010" class="elsevierStylePara elsevierViewall">A CT-scan performed to evaluate any possible lung involvement, revealed multiple solid pulmonary nodules with bilateral distribution and upper-lobe predominance. These nodules showed ill-defined margins and exhibited a halo of ground-glass attenuation, or “halo sign” (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a> – left). In the clinical context, these findings corresponded to hemorrhagic infarcts and were highly suggestive of angioinvasive aspergillosis. Nevertheless, other much less common entities, such as Mucor and Candida, herpes simplex and cytomegalovirus, Wegener granulomatosis, Kaposi sarcoma and hemorrhagic metastases may present with similar findings on CT.<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">1</span></a></p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">Antifungal therapy for aspergillosis was administered and the patient made good progress. A follow-up CT performed after 3 weeks of treatment showed cavitation within the nodules, with a small solid component. This is called the “air crescent sign” (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a> – right), and appears in 50% of the cases.<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">2</span></a> When it is seen after the “halo sign”, it reaffirms the diagnosis of aspergillosis and represents the separation of necrotic and healthy parenchyma.<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">1</span></a></p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Sánchez VV, García AG, Garmendia FS. Un caso de aspergilosis angioinvasiva. Arch Bronconeumol. 2017;53:273.</p>" ] ] "multimedia" => array:1 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 642 "Ancho" => 1500 "Tamanyo" => 116648 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Initial CT scan (left image) showing ill-defined nodules (arrow) with upper lobe predominance. Follow-up CT scan (right image) performed 3 weeks after starting treatment showing cavitation of known nodules.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:2 [ 0 => array:3 [ "identificador" => "bib0015" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Spectrum of pulmonary aspergillosis: histologic, clinical, and radiologic findings" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "T. Franquet" 1 => "N.L. Müller" 2 => "A. Giménez" 3 => "P. Guembe" 4 => "J. de La Torre" 5 => "S. Bagué" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1148/radiographics.21.4.g01jl03825" "Revista" => array:6 [ "tituloSerie" => "Radiographics" "fecha" => "2001" "volumen" => "21" "paginaInicial" => "825" "paginaFinal" => "837" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11452056" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0020" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pulmonary aspergillosis: what CT can offer before it is too late!" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "A. Prasad" 1 => "K. Agarwal" 2 => "D. Deepak" 3 => "S.S. Atwal" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.7860/JCDR/2016/21443.8210" "Revista" => array:6 [ "tituloSerie" => "JCDR" "fecha" => "2016" "volumen" => "10" "paginaInicial" => "TE01" "paginaFinal" => "TE05" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/27630924" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15792129/0000005300000005/v1_201704280925/S1579212916303226/v1_201704280925/en/main.assets" "Apartado" => array:4 [ "identificador" => "21342" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Clinical Image" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/15792129/0000005300000005/v1_201704280925/S1579212916303226/v1_201704280925/en/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212916303226?idApp=UINPBA00003Z" ]
| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 4 | 2 | 6 |
| 2024 October | 51 | 17 | 68 |
| 2024 September | 53 | 13 | 66 |
| 2024 August | 74 | 35 | 109 |
| 2024 July | 50 | 24 | 74 |
| 2024 June | 60 | 44 | 104 |
| 2024 May | 77 | 39 | 116 |
| 2024 April | 45 | 27 | 72 |
| 2024 March | 43 | 15 | 58 |
| 2024 February | 39 | 19 | 58 |
| 2023 June | 1 | 0 | 1 |
| 2023 March | 11 | 3 | 14 |
| 2023 February | 50 | 21 | 71 |
| 2023 January | 48 | 32 | 80 |
| 2022 December | 62 | 37 | 99 |
| 2022 November | 69 | 35 | 104 |
| 2022 October | 70 | 36 | 106 |
| 2022 September | 50 | 32 | 82 |
| 2022 August | 52 | 34 | 86 |
| 2022 July | 53 | 55 | 108 |
| 2022 June | 53 | 32 | 85 |
| 2022 May | 42 | 33 | 75 |
| 2022 April | 71 | 39 | 110 |
| 2022 March | 37 | 57 | 94 |
| 2022 February | 50 | 42 | 92 |
| 2022 January | 44 | 42 | 86 |
| 2021 December | 49 | 43 | 92 |
| 2021 November | 43 | 41 | 84 |
| 2021 October | 65 | 46 | 111 |
| 2021 September | 36 | 40 | 76 |
| 2021 August | 40 | 33 | 73 |
| 2021 July | 49 | 23 | 72 |
| 2021 June | 49 | 29 | 78 |
| 2021 May | 38 | 38 | 76 |
| 2021 April | 94 | 89 | 183 |
| 2021 March | 42 | 25 | 67 |
| 2021 February | 42 | 23 | 65 |
| 2021 January | 43 | 15 | 58 |
| 2020 December | 32 | 18 | 50 |
| 2020 November | 34 | 10 | 44 |
| 2020 October | 44 | 17 | 61 |
| 2020 September | 20 | 7 | 27 |
| 2020 August | 40 | 15 | 55 |
| 2020 July | 26 | 25 | 51 |
| 2020 June | 14 | 6 | 20 |
| 2020 May | 36 | 8 | 44 |
| 2020 April | 34 | 13 | 47 |
| 2020 March | 16 | 9 | 25 |
| 2020 February | 35 | 13 | 48 |
| 2020 January | 36 | 14 | 50 |
| 2019 December | 38 | 15 | 53 |
| 2019 November | 46 | 11 | 57 |
| 2019 October | 14 | 10 | 24 |
| 2019 September | 12 | 4 | 16 |
| 2019 August | 29 | 10 | 39 |
| 2019 July | 30 | 9 | 39 |
| 2019 June | 11 | 12 | 23 |
| 2019 May | 27 | 14 | 41 |
| 2019 April | 96 | 10 | 106 |
| 2019 March | 26 | 20 | 46 |
| 2019 February | 28 | 12 | 40 |
| 2019 January | 17 | 10 | 27 |
| 2018 December | 18 | 13 | 31 |
| 2018 November | 52 | 14 | 66 |
| 2018 October | 69 | 17 | 86 |
| 2018 September | 22 | 6 | 28 |
| 2018 May | 14 | 0 | 14 |
| 2018 April | 42 | 10 | 52 |
| 2018 March | 49 | 3 | 52 |
| 2018 February | 64 | 5 | 69 |
| 2018 January | 104 | 6 | 110 |
| 2017 December | 67 | 7 | 74 |
| 2017 November | 32 | 7 | 39 |
| 2017 October | 26 | 11 | 37 |
| 2017 September | 27 | 10 | 37 |
| 2017 August | 23 | 13 | 36 |
Show all
