was read the article
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"en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>" "titulo" => "Etiological Pattern of Community-Acquired Pneumonia: Importance of the Geographical Factor" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "156" "paginaFinal" => "157" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Patrón etiológico de la neumonía adquirida en la comunidad: importancia del factor geográfico" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1515 "Ancho" => 1667 "Tamanyo" => 94872 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Seasonal distribution of causative pathogens of community-acquired pneumonia.</p> <p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Winter: December to February, Spring: March to May, Summer: June to August, Fall: September to November.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Agustín Julián-Jiménez, Manuel Flores Chacartegui, Ana Nieves Piqueras-Martínez" "autores" => array:3 [ 0 => array:2 [ "nombre" => "Agustín" "apellidos" => "Julián-Jiménez" ] 1 => array:2 [ "nombre" => "Manuel" "apellidos" => "Flores Chacartegui" ] 2 => array:2 [ "nombre" => "Ana Nieves" "apellidos" => "Piqueras-Martínez" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0300289613002366" "doi" => "10.1016/j.arbres.2013.08.001" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 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"tieneTextoCompleto" => true "saludo" => "<span class="elsevierStyleItalic">To the Editor</span>:" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "156" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Felipe Andreo García, José Sanz Santos, Maria Llatjós Sanuy, Juan Ruiz Manzano" "autores" => array:4 [ 0 => array:4 [ "nombre" => "Felipe" "apellidos" => "Andreo García" "email" => array:1 [ 0 => "fandreo@separ.es" ] "referencia" => array:3 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff0015" ] 2 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "José" "apellidos" => "Sanz Santos" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 2 => array:3 [ "nombre" => "Maria" "apellidos" => "Llatjós Sanuy" "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff0015" ] ] ] 3 => array:3 [ "nombre" => "Juan" "apellidos" => "Ruiz Manzano" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Servicio de Neumología, Hospital Universitario Germans Trias i Pujol, Badalona, Barcelona, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicio de Anatomía Patológica, Hospital Universitario Germans Trias i Pujol, Badalona, Barcelona, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] 2 => array:3 [ "entidad" => "Centro de Investigación Biomédica en Red de Enfermedades Respiratorias, Instituto de Salud Carlos III, Bunyola, Mallorca, Spain" "etiqueta" => "c" "identificador" => "aff0015" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Punción guiada por ultrasonografía endobronquial sin aspiración: ¿y el bloque celular?" ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">We read with great interest the article by Rodriguez et al.<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> in which the authors present a study on mediastinal sampling using endobronchial ultrasound guided fine-needle capillary sampling (EBUS-FNC) instead of transbronchial needle aspiration (EBUS-TBNA), in which a negative pressure is applied via syringe. The authors report the interesting benefits of not applying suction to EBUS-guided puncture: the technique is simpler, procedure time is reduced, and adequate and representative material comparable to that of EBUS-TBNA may be obtained with less contamination from bleeding. However, a very important issue not highlighted in the article is the efficiency of the technique in obtaining cell blocks (CB). Madan and Guleria<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> recently expressed concern regarding the possible differential yield when the histological core is obtained without the application of suction.</p><p id="par0010" class="elsevierStylePara elsevierViewall">The preparation of CB from EBUS-TBNA samples is a simple way to provide additional information in the diagnosis of lung cancer. In our experience<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> in lung cancer, CB obtained by EBUS-TBNA generally provided clinically relevant information in 83 of 270 patients (30.7%). Puncture was repeated up to three times and preservation of material for CB was possible in almost half of the aspirates. Of a total of 697 transbronchial aspirates, CB were available in 334 (47.9%). In 50 cases (7.2%), conventional extensions were not diagnostic while the CB were, and the malignancy diagnosed from extensions could be subtyped in four patients. Genetic analyses could also be performed from CB in 60% of patients with adenocarcinoma. CB samples were processed by air drying and coagulation on filter paper. For this, a blood sample is needed, and that is more likely to be obtained when negative pressure is applied with a syringe. Since the absence of suction produces less trauma, this technique is less likely to ensure a clot formation.</p><p id="par0015" class="elsevierStylePara elsevierViewall">Several oncology societies<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> have published guidelines recommending the necessary identification of molecular abnormalities for the initiation of specific treatment. Even today and certainly in the near future, EBUS will face the challenge of demonstrating its usefulness in the comprehensive analysis of all the newly available molecular studies<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a> in advanced neoplastic diseases, for which histopathological samples obtained by biopsy or surgical techniques have been routinely used.</p><p id="par0020" class="elsevierStylePara elsevierViewall">It must be shown that useful CB can be obtained (even if they are prepared in liquid medium) by FNC instead of TBNA in an adequate proportion of cases, without increasing the number of punctures. A direct comparison is needed of the equivalence of the yield of the CB material obtained by each technique in terms of amounts (differences in cellularity) and quality for immunohistochemistry and molecular analyses, and not only the purely diagnostic yield. Until such evidence is available, we believe that FNC can be considered a useful alternative in cases where contamination by bleeding for immediate examination may render the sample inadequate.</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflicts of Interest</span><p id="par0025" class="elsevierStylePara elsevierViewall">The authors declare no conflicts of interest.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:2 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Conflicts of Interest" ] 1 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Andreo García F, Sanz Santos J, Llatjós Sanuy M, Ruiz Manzano J. Punción guiada por ultrasonografía endobronquial sin aspiración: ¿y el bloque celular? Arch Bronconeumol. 2014;50:156.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:5 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Modified technique for obtaining mediastinal samples with endobronchial ultrasound-guided transbronchial needle aspiration: results from a prospective observational study" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "F. Rodríguez" 1 => "L.M. Seijo" 2 => "P.A. Sánchez" 3 => "J.J. Zulueta" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.arbres.2012.10.006" "Revista" => array:6 [ "tituloSerie" => "Arch Bronconeumol" "fecha" => "2013" "volumen" => "49" "paginaInicial" => "135" "paginaFinal" => "139" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23265621" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Endobronchial ultrasound needle biopsy with and without aspiration: the “core” issue" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "K. Madan" 1 => "R. Guleria" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1378/chest.12-2291" "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "2013" "volumen" => "143" "paginaInicial" => "281" "paginaFinal" => "282" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23276872" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Contribution of cell blocks obtained through endobronchial ultrasound-guided transbronchial needle aspiration to the diagnosis of lung cancer" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "J. Sanz-Santos" 1 => "P. Serra" 2 => "F. Andreo" 3 => "M. Llatjós" 4 => "E. Castellà" 5 => "E. Monsó" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1186/1471-2407-12-34" "Revista" => array:5 [ "tituloSerie" => "BMC Cancer" "fecha" => "2012" "volumen" => "12" "paginaInicial" => "34" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22264305" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Recomendaciones para la determinación de biomarcadores en el carcinoma de pulmón no microcítico avanzado. Consenso nacional de la Sociedad Española de Anatomía Patológica y de la Sociedad Española de Oncología Médica" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "J.J. Gómez" 1 => "J. de Castro" 2 => "A. Concha" 3 => "E. Felip" 4 => "D. Isla" 5 => "F. López-Ríos" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Rev Esp Patol" "fecha" => "2012" "volumen" => "45" "paginaInicial" => "14" "paginaFinal" => "28" ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "New driver mutations in non-small-cell lung cancer" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "W. Pao" 1 => "N. Girard" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/S1470-2045(10)70087-5" "Revista" => array:6 [ "tituloSerie" => "Lancet Oncol" "fecha" => "2011" "volumen" => "12" "paginaInicial" => "175" "paginaFinal" => "180" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21277552" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15792129/0000005000000004/v1_201404030045/S1579212914000767/v1_201404030045/en/main.assets" "Apartado" => array:4 [ "identificador" => "14576" "tipo" => "SECCION" "es" => array:2 [ "titulo" => "Letters to the editor" "idiomaDefecto" => true ] "idiomaDefecto" => "es" ] "PDF" => "https://static.elsevier.es/multimedia/15792129/0000005000000004/v1_201404030045/S1579212914000767/v1_201404030045/en/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212914000767?idApp=UINPBA00003Z" ]
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2014 October | 21 | 14 | 35 |
2014 September | 27 | 11 | 38 |
2014 August | 32 | 12 | 44 |
2014 July | 30 | 13 | 43 |
2014 May | 0 | 2 | 2 |
2014 April | 1 | 0 | 1 |