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[ "imagen" => "gr1.jpeg" "Alto" => 1515 "Ancho" => 1667 "Tamanyo" => 94872 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Seasonal distribution of causative pathogens of community-acquired pneumonia.</p> <p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Winter: December to February, Spring: March to May, Summer: June to August, Fall: September to November.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Agustín Julián-Jiménez, Manuel Flores Chacartegui, Ana Nieves Piqueras-Martínez" "autores" => array:3 [ 0 => array:2 [ "nombre" => "Agustín" "apellidos" => "Julián-Jiménez" ] 1 => array:2 [ "nombre" => "Manuel" "apellidos" => "Flores Chacartegui" ] 2 => array:2 [ "nombre" => "Ana Nieves" "apellidos" => "Piqueras-Martínez" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0300289613002366" "doi" => "10.1016/j.arbres.2013.08.001" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0300289613002366?idApp=UINPBA00003Z" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212914000755?idApp=UINPBA00003Z" "url" => "/15792129/0000005000000004/v1_201404030045/S1579212914000755/v1_201404030045/en/main.assets" ] "en" => array:15 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>" "titulo" => "Bronchioloalveolar Carcinoma: Time for a New Term" "tieneTextoCompleto" => true "saludo" => "To the Editor:" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "157" "paginaFinal" => "158" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "José Sanz-Santos, Felipe Andreo, Juan Ruiz-Manzano" "autores" => array:3 [ 0 => array:4 [ "nombre" => "José" "apellidos" => "Sanz-Santos" "email" => array:1 [ 0 => "34057jss@comb.es" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "Felipe" "apellidos" => "Andreo" ] 2 => array:2 [ "nombre" => "Juan" "apellidos" => "Ruiz-Manzano" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Servicio de Neumología, Hospital Universitario Germans Trias i Pujol, Badalona, Barcelona, Spain" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Carcinoma broncoalveolar: un término a actualizar" ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">In the July issue of <span class="elsevierStyleItalic">Archivos de Bronconeumología</span>, Dr. Paraschiv and partners published a case in the Letters to the Editor section.<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> These authors describe a case of a male, 35-year smoker with a 35 pack-year history, consulting with symptoms of fatigue, cough and chest pain of 2-week duration. Chest X-ray revealed airspace involvement in the form of patchy consolidation with air bronchogram that was confirmed on a computed tomography (CT) scan of the chest. The initial working diagnosis was an infectious process, although the lack of response to antibiotic therapy led to the clinical suspicion of malignancy. The patient died and definitive diagnosis of bronchioloalveolar carcinoma was established at necropsy. Although the unusual nature of this clinical case makes it interesting, we consider the final diagnosis of bronchioloalveolar carcinoma unclear.</p><p id="par0010" class="elsevierStylePara elsevierViewall">The term “bronchioloalveolar carcinoma” has been used traditionally to describe lung adenocarcinomas presenting lepidic growth in the pathological specimen. Lepidic growth is the proliferation of neoplastic cells that line the surfaces of the alveolar walls, preserving lung architecture. The radiologic correlation of this type of tumor is usually the finding of ground-glass opacities or affected alveolar airspace areas that may be associated with consolidated and/or air bronchogram areas. From the clinical point of view, this type of tumor includes an amalgam of entities with completely different treatments and prognosis, ranging from adenocarcinomas presenting as ground-glass opacities in chest CT,<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> with very good prognosis after surgical resection (survival rates of 100% at 5 years after surgery),<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> to tumors, such as the one described in the clinical case that begins with extensive multilobar disease. Accordingly, the terminology “bronchioloalveolar carcinoma” is considered imprecise, since it encompasses tumors with very different clinical behaviors. For this reason, the recent classification of lung adenocarcinoma jointly published in February 2011 by the European Respiratory Society (ERS), the American Thoracic Society (ATS), and the International Association for the Study of Lung Cancer (IASLC)<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> recommends forsaking the term “bronchioloalveolar carcinoma”. In this new classification of lung adenocarcinoma, five categories that were encompassed under the concept of bronchioloalveolar carcinoma are considered:<ul class="elsevierStyleList" id="lis0005"><li class="elsevierStyleListItem" id="lsti0005"><span class="elsevierStyleLabel">1)</span><p id="par0015" class="elsevierStylePara elsevierViewall">In situ adenocarcinoma.</p></li><li class="elsevierStyleListItem" id="lsti0010"><span class="elsevierStyleLabel">2)</span><p id="par0020" class="elsevierStylePara elsevierViewall">Minimally invasive adenocarcinoma.</p></li><li class="elsevierStyleListItem" id="lsti0015"><span class="elsevierStyleLabel">3)</span><p id="par0025" class="elsevierStylePara elsevierViewall">Predominantly lepidic adenocarcinoma (non-mucinous).</p></li><li class="elsevierStyleListItem" id="lsti0020"><span class="elsevierStyleLabel">4)</span><p id="par0030" class="elsevierStylePara elsevierViewall">Predominantly invasive adenocarcinoma with non-mucinous lepidic component.</p></li><li class="elsevierStyleListItem" id="lsti0025"><span class="elsevierStyleLabel">5)</span><p id="par0035" class="elsevierStylePara elsevierViewall">Invasive mucinous adenocarcinoma.</p></li></ul></p><p id="par0040" class="elsevierStylePara elsevierViewall">In conclusion, the diagnosis of bronchioloalveolar carcinoma should be avoided, as recommended by the new adenocarcinoma classification, and we should refer instead to any of the five specified categories.</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Funding</span><p id="par0045" class="elsevierStylePara elsevierViewall">None.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:3 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Funding" ] 1 => array:2 [ "identificador" => "xack77687" "titulo" => "Acknowledgements" ] 2 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Sanz-Santos J, Andreo F, Ruiz-Manzano J. Carcinoma broncoalveolar: un término a actualizar. Arch Bronconeumol. 2014;50:157–158.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:4 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Carcinoma broncoalveolar en un paciente joven: caso clínico" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "B. Paraschiv" 1 => "C.L. Toma" 2 => "C. Diacomu" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.arbres.2013.01.005" "Revista" => array:6 [ "tituloSerie" => "Arch Bronconeumol" "fecha" => "2013" "volumen" => "49" "paginaInicial" => "315" "paginaFinal" => "316" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23490086" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Small adenocarcinoma of the lung. Histologic characteristics and prognosis" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "M. Noguchi" 1 => "A. Morikawa" 2 => "M. Kawasaki" 3 => "Y. Matsuno" 4 => "T. Yamada" 5 => "S. Hirohashi" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Cancer" "fecha" => "1995" "volumen" => "75" "paginaInicial" => "2844" "paginaFinal" => "2852" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7773933" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Peripheral lung adenocarcinoma: correlation of thin-section CT findings with histologic prognostic factors and survival" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "T. Aoki" 1 => "Y. Tomoda" 2 => "H. Watanabe" 3 => "H. Nakata" 4 => "T. Kasai" 5 => "H. Hashimoto" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Radiology" "fecha" => "2001" "volumen" => "3" "paginaInicial" => "803" "paginaFinal" => "809" ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society international multidisciplinary classification of lung adenocarcinoma" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "W.D. Travis" 1 => "E. Brambilla" 2 => "M. Noguchi" 3 => "A.G. Nicholson" 4 => "K.R. Geisinger" 5 => "Y. Yatabe" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/JTO.0b013e318206a221" "Revista" => array:7 [ "tituloSerie" => "J Thorac Oncol" "fecha" => "2011" "volumen" => "6" "paginaInicial" => "244" "paginaFinal" => "285" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21252716" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0140673600028154" "estado" => "S300" "issn" => "01406736" ] ] ] ] ] ] ] ] ] ] ] "agradecimientos" => array:1 [ 0 => array:4 [ "identificador" => "xack77687" "titulo" => "Acknowledgements" "texto" => "<p id="par0050" class="elsevierStylePara elsevierViewall">None.</p>" "vista" => "all" ] ] ] "idiomaDefecto" => "en" "url" => "/15792129/0000005000000004/v1_201404030045/S1579212914000706/v1_201404030045/en/main.assets" "Apartado" => array:4 [ "identificador" => "14576" "tipo" => "SECCION" "es" => array:2 [ "titulo" => "Letters to the editor" "idiomaDefecto" => true ] "idiomaDefecto" => "es" ] "PDF" => "https://static.elsevier.es/multimedia/15792129/0000005000000004/v1_201404030045/S1579212914000706/v1_201404030045/en/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212914000706?idApp=UINPBA00003Z" ]
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