Editorial
Noninvasive Mechanical Ventilation. Reflections on Home Monitoring
Ventilación mecánica no invasiva. Reflexiones sobre la monitorización a domicilio
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Reflections on Home Monitoring" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "85" "paginaFinal" => "86" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Manel Luján, Xavier Pomares" "autores" => array:2 [ 0 => array:4 [ "nombre" => "Manel" "apellidos" => "Luján" "email" => array:1 [ 0 => "mlujan@tauli.cat" ] "referencia" => array:3 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] 2 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "Xavier" "apellidos" => "Pomares" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servei de Pneumologia, Hospital de Sabadell, Corporació Parc Taulí, Universitat Autònoma de Barcelona, Sabadell , Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "CIBERES, Ciber de enfermedades respiratorias, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Ventilación mecánica no invasiva. Reflexiones sobre la monitorización a domicilio" ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Home-based noninvasive ventilation (NIV) was initiated in the early nineties in our environment as a treatment for patients with chronic respiratory failure, secondary to restrictive ventilatory disorders or neuromuscular disease. Subsequently, NIV also proved effective in patients with obesity-related hypoventilation syndromes, and to a lesser extent in some patients with chronic obstructive pulmonary disease in stable phase. There was a simultaneous growth in interest in whether the selected parameters suited the patients’ needs when using NIV in the home setting. Thus, the use of continuous overnight pulse oximetry monitoring as the gold standard for home monitoring in centers prescribing ventilation became widespread. The main issue with pulse oximetry has undoubtedly been its lack of specificity for correlation with certain patterns of patient–ventilator interaction. In other words, the effects of adverse events (desaturation) were detected, but there was a limited understanding of the underlying causes, and therefore of the potential solutions.</p><p id="par0010" class="elsevierStylePara elsevierViewall">In order to improve the performance of pulse oximetry, a series of simplified polygraphic systems have appeared in recent years, mostly in association with the ventilator manufacturers. These systems provide a set of data on the patient's respiratory mechanics that can be downloaded from the ventilator's internal memory. The main purpose is to provide the clinician with additional information on the potential reasons for inadequate ventilation periods and the pathophysiological causes (unintentional interface leaks, uncorrected upper airway episodes, asynchrony, etc.). Over the years, almost all manufacturers of ventilation systems have developed their own download system and data display.<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> However, in our view, the performance and reliability of these devices, which are widely used today, should be analyzed in depth.</p><p id="par0015" class="elsevierStylePara elsevierViewall">The first premise to be considered by the clinician is that a number of values provided by these software systems are not measured directly. In single-tube systems, the most widely used in home NIV, these values are actually estimated from the internal measurements of the ventilator. In such systems, the ventilator's single tube detects all the gas provided during the different phases of the respiratory cycle, but must discriminate between the amount corresponding to the tidal volume and leaks (both intentional and unintentional). It follows that these two parameters are estimated from a series of algorithms. The first surprising aspect is that virtually no home ventilator has a system to discriminate the value of intentional leak, either by enabling a leak test (building a pressure–leakage curve, with occlusion distal to the leakage site) or by selecting the specific interface used in a ventilator-integrated menu. Obviously, the value of intentional leak is different depending on whether a full-face interface, a nasal interface or an Adams model is used. It is important to take this parameter into account in order to discriminate between intentional and unintentional leaks, and also to estimate the tidal volume.</p><p id="par0020" class="elsevierStylePara elsevierViewall">To assess reliability in the laboratory setting, Contal et al.<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> carried out one of the first validation analyses of these estimations. The study analyzed seven ventilators in a controlled environment with specific respiratory mechanics, effort and level of continuous incremental leak. The results showed that all ventilators analyzed underestimated the tidal volume to a greater or lesser extent. Also, there was a great disparity between leakage estimations. In our view, the most important issue in this study is not the magnitude of the deviations, but the differences between devices, which are attributable more to differences in estimation algorithms than to the variability of the sensors used. Using a similar experimental model, our group showed that a possible reason for underestimation could be a lack of compensation for pressure loss in the tube.<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> Assuming that ventilators calculate leakage as a pressure function, it is understandable that estimations may vary depending on whether the pressure is measured within the ventilator itself or at the end of a 2-m long tube.</p><p id="par0025" class="elsevierStylePara elsevierViewall">These results were obtained in experimental designs of continuous leakage. However, the actual behavior of leakage in the clinical setting should not be simplified to such an extent. A subsequent design analyzed the behavior of these parameters using a dynamic random leak model, with predominance in one or other phase of the cycle. The results of the inspiration-dominant leakage model (the most plausible from a clinical point of view) were diametrically opposed to those of the continuous leakage model. That is to say, tidal volume was overestimated in percentages of up to 30% of the actual volume.<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> The fact that many of these ventilators also incorporate dual control ventilation modes (pressure support with guaranteed volume) is particularly worrying, since the device makes decisions independently in these modes (increase or decrease in pressure support) based on the estimated tidal volume.</p><p id="par0030" class="elsevierStylePara elsevierViewall">Clearly, all these issues are food for thought for manufacturers and NIV-prescribing specialists. It is little wonder, then, that the SomnoNIV expert panel grants a low level of evidence to software monitoring systems, since they are not clinically validated or based on the recommendations of scientific societies.<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a> Nor does the limited clinical experience in the literature invite confidence.<a class="elsevierStyleCrossRefs" href="#bib0030"><span class="elsevierStyleSup">6,7</span></a> Obviously, the estimation algorithms for ventilator settings are developed by manufacturers, and are the responsibility of their respective departments for research and development. However, in view of the reliability results observed by independent groups, such algorithms should be reported and homogenized. If this is not possible, the alternative should be the development of independent monitoring tools offering the parameters needed to provide the minimal required information on patient–ventilator interaction in the patient's usual environment. Such devices should be able to serve the dual function of transmitting real-time information, while storing it for later analysis. In other words, there is a requirement for independent polygraph systems, with real signal capture in the ventilator branches, that are simple enough to be used in the patient's home, similar to the monitors used in sleep disordered breathing units.</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Funding</span><p id="par0035" class="elsevierStylePara elsevierViewall">None.</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Conflicts of Interest</span><p id="par0040" class="elsevierStylePara elsevierViewall">The authors declare no conflict of interest.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:3 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Funding" ] 1 => array:2 [ "identificador" => "sec0010" "titulo" => "Conflicts of Interest" ] 2 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Luján M, Pomares X. Ventilación mecánica no invasiva. Reflexiones sobre la monitorización a domicilio. Arch Bronconeumol. 2014;50:85–86.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:7 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Software de monitorización de ventilación mecánica domiciliaria: ¿medir más o medir mejor?" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "M. Luján" 1 => "A. Sogo" 2 => "E. Monsó" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.arbres.2011.10.010" "Revista" => array:6 [ "tituloSerie" => "Arch Bronconeumol" "fecha" => "2012" "volumen" => "48" "paginaInicial" => "170" "paginaFinal" => "178" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22206599" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Monitoring of non-invasive ventilation by built-in software of home bi-level ventilators: a bench study" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "O. Contal" 1 => "L. Vignaux" 2 => "C. Combescure" 3 => "J.L. Pepin" 4 => "P. Jolliet" 5 => "J.P. 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Sogo" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Bronconeumol" "fecha" => "2013" "volumen" => "49" "numero" => "Suppl. 2" "paginaInicial" => "302" "paginaFinal" => "303" ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Nocturnal monitoring of home noninvasive ventilation: the contribution of simple tools such as pulse oximetry, capnography, built-in ventilator software and autonomic markers of sleep fragmentation" "autores" => array:1 [ 0 => array:3 [ "colaboracion" => "SomnoNIV group" "etal" => false "autores" => array:3 [ 0 => "J.P. Janssens" 1 => "J.C. Borel" 2 => "J.L. 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Casan" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1159/000341983" "Revista" => array:6 [ "tituloSerie" => "Respiration" "fecha" => "2013" "volumen" => "85" "paginaInicial" => "132" "paginaFinal" => "136" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23018542" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15792129/0000005000000003/v1_201403120155/S157921291400038X/v1_201403120155/en/main.assets" "Apartado" => array:4 [ "identificador" => "14568" "tipo" => "SECCION" "es" => array:2 [ "titulo" => "Editorial" "idiomaDefecto" => true ] "idiomaDefecto" => "es" ] "PDF" => "https://static.elsevier.es/multimedia/15792129/0000005000000003/v1_201403120155/S157921291400038X/v1_201403120155/en/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S157921291400038X?idApp=UINPBA00003Z" ]
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| 2017 August | 39 | 13 | 52 |
| 2017 July | 45 | 10 | 55 |
| 2017 June | 45 | 11 | 56 |
| 2017 May | 45 | 10 | 55 |
| 2017 April | 26 | 6 | 32 |
| 2017 March | 34 | 17 | 51 |
| 2017 February | 16 | 5 | 21 |
| 2017 January | 16 | 5 | 21 |
| 2016 December | 24 | 5 | 29 |
| 2016 November | 33 | 9 | 42 |
| 2016 October | 33 | 23 | 56 |
| 2016 September | 47 | 17 | 64 |
| 2016 August | 46 | 12 | 58 |
| 2016 July | 36 | 11 | 47 |
| 2016 March | 2 | 0 | 2 |
| 2016 February | 1 | 0 | 1 |
| 2015 December | 3 | 0 | 3 |
| 2015 October | 57 | 4 | 61 |
| 2015 September | 111 | 11 | 122 |
| 2015 August | 165 | 14 | 179 |
| 2015 July | 71 | 11 | 82 |
| 2015 June | 36 | 3 | 39 |
| 2015 May | 55 | 11 | 66 |
| 2015 April | 31 | 9 | 40 |
| 2015 March | 37 | 5 | 42 |
| 2015 February | 31 | 7 | 38 |
| 2015 January | 35 | 12 | 47 |
| 2014 December | 27 | 8 | 35 |
| 2014 November | 26 | 4 | 30 |
| 2014 October | 52 | 17 | 69 |
| 2014 September | 33 | 11 | 44 |
| 2014 August | 24 | 13 | 37 |
| 2014 July | 40 | 11 | 51 |
| 2014 June | 43 | 24 | 67 |
| 2014 May | 2 | 2 | 4 |
| 2014 April | 0 | 1 | 1 |
| 2014 March | 1 | 1 | 2 |
Show all
