Clinical Image
Chemotherapy-Induced Secondary Pneumothorax
Neumotórax secundario inducido por quimioterapia
Fernando Bazan
, Ivan Vollmer, Angel Gayete
Corresponding author
Servicio de Radiodiagnóstico, Hospital del Mar, Parc de Salut Mar, Barcelona, Spain
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He had received his third chemotherapy session two days previously (temozolamide and bevacizumab).</p><p id="par0010" class="elsevierStylePara elsevierViewall">A chest X-ray (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>A) and computed tomography (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>B, C) were performed which showed right humeral-axillary sarcoma, multiple lung metastases, some which were cavitated, and mild bilateral pneumothorax. In view of the radiological findings and the correlating clinical picture, a diagnosis was made of pneumothorax due to cavitation of metastases induced by chemotherapy, since the metastases were not cavitated in the previous examination.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">The bilateral pneumothorax was treated conservatively and resolved fully 10 days later. Unfortunately, the patient died several weeks later due to complications from his lung metastases.</p><p id="par0020" class="elsevierStylePara elsevierViewall">Primary and metastatic lung neoplasms can cavitate spontaneously or after chemotherapy: if a cavitated lesion is located peripherally, it can open into the pleural space and cause spontaneous pneumothorax.<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1,2</span></a> The neoplasms that most frequently present this characteristic are the peripheral sarcomas: osteosarcoma, synovial sarcoma and angiosarcoma.<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1,2</span></a></p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Bazan F, Vollmer I, Gayete A. Neumotórax secundario inducido por quimioterapia. Arch Bronconeumol. 2014;50:44.</p>" ] ] "multimedia" => array:1 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 606 "Ancho" => 1800 "Tamanyo" => 212232 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Radiograph (A) and computed tomography (B, C) of the chest in which the sarcoma-axillary level right humerus (orange star) mass in the left lung (white arrow), several solid nodules (orange arrows) are visualized and cavitation (blue arrows) and mild bilateral pneumothorax (blue stars).</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:2 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Spontaneous pneumothorax after chemotherapy for sarcoma with lung metastases: case report and consideration of pathogenesis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "A. Fiorelli" 1 => "G. Vicidomini" 2 => "F. Napolitano" 3 => "M. Santini" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.3978/j.issn.2072-1439.2010.12.01" "Revista" => array:6 [ "tituloSerie" => "J Thorac Dis" "fecha" => "2011" "volumen" => "3" "paginaInicial" => "138" "paginaFinal" => "140" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22263077" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A comprehensive review of spontaneous pneumothorax complicating sarcoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "J.B. Hoag" 1 => "M. Sherman" 2 => "Q. Fasihuddin" 3 => "M.E. Lund" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1378/chest.09-2292" "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "2010" "volumen" => "138" "paginaInicial" => "510" "paginaFinal" => "518" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20382720" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15792129/0000005000000001/v1_201402160026/S1579212913002061/v1_201402160026/en/main.assets" "Apartado" => array:4 [ "identificador" => "21342" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Clinical Image" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/15792129/0000005000000001/v1_201402160026/S1579212913002061/v1_201402160026/en/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212913002061?idApp=UINPBA00003Z" ]
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