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Usefulness CT-guided F.N.A.C. in the Diagnosis of Mediastinal Lesions
Utilidad de la PAAF guiada por TC en el diagnóstico de lesiones mediastínicas
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"Mohammad" "apellidos" => "Hossein Boskabady" ] 1 => array:2 [ "nombre" => "Mohamad" "apellidos" => "Javad Eslamizade" ] 2 => array:2 [ "nombre" => "Abas" "apellidos" => "Tabatabaei" ] 3 => array:2 [ "nombre" => "Habib" "apellidos" => "Nemati" ] 4 => array:2 [ "nombre" => "Fariba" "apellidos" => "Mansouri" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212910700562?idApp=UINPBA00003Z" "url" => "/15792129/0000004600000005/v1_201305150453/S1579212910700562/v1_201305150453/en/main.assets" ] "en" => array:15 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Original Article</span>" "titulo" => "Usefulness CT-guided F.N.A.C. in the Diagnosis of Mediastinal Lesions" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "223" "paginaFinal" => "229" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Virginia Pérez Dueñas, Isabel Torres Sánchez, Francisco García Río, Emilio Valbuena Durán, Blanca Vicandi Plaza, Jose María Viguer García-Moreno" "autores" => array:6 [ 0 => array:4 [ "nombre" => "Virginia" "apellidos" => "Pérez Dueñas" "email" => array:1 [ 0 => "virpedue@gmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor1" ] ] ] 1 => array:3 [ "nombre" => "Isabel" "apellidos" => "Torres Sánchez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 2 => array:3 [ "nombre" => "Francisco" "apellidos" => "García Río" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] ] 3 => array:3 [ "nombre" => "Emilio" "apellidos" => "Valbuena Durán" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 4 => array:3 [ "nombre" => "Blanca" "apellidos" => "Vicandi Plaza" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff3" ] ] ] 5 => array:3 [ "nombre" => "Jose" "apellidos" => "María Viguer García-Moreno" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff3" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Servicios de Radiología, Hospital Universitario La Paz, Madrid, Spain" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:3 [ "entidad" => "Servicios de Neumología, Hospital Universitario La Paz, Madrid, Spain" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] 2 => array:3 [ "entidad" => "Servicios de Anatomía Patológica, Hospital Universitario La Paz, Madrid, Spain" "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff3" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Utilidad de la PAAF guiada por TC en el diagnóstico de lesiones mediastínicas" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2009-09-20" "fechaAceptado" => "2010-02-28" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec156021" "palabras" => array:6 [ 0 => "Mediastinal lesions" 1 => "Computed tomography" 2 => "Fine needle aspiration" 3 => "Cytology" 4 => "Sensitivity" 5 => "Specificity" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec156022" "palabras" => array:6 [ 0 => "Lesiones mediastínicas" 1 => "Tomografía computerizada" 2 => "Punción aspiración con aguja fina" 3 => "Citología" 4 => "Sensibilidad" 5 => "Especificidad" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">To evaluate the diagnostic accuracy of the percutaneous fine needle aspiration cytology (FNAC) for mediastinal lesions by using histology or follow-up clinical diagnosis as gold standard.</p> <span class="elsevierStyleSectionTitle">Patients and Methods</span><p class="elsevierStyleSimplePara elsevierViewall">CT-guided percutaneous FNAC was performed on 131 patients with mediastinal lesions. Helical CT was used with 3–10mm image thickness range and low radiation dose (40mAs, 120kV). Samples were immediately examined by a cytologist to determine if they were representative. Histological samples were obtained by means of biopsy or resection specimens in 73 patients and clinical follow-up in 50.</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">The material was satisfactory for diagnosis in 126 patients (95.2 %), in whom 103 lesions (78.6%) were considered malignant (62 primary tumours and 41 metastases) and 23 (17.6%) benign. In the 123 patients with clinical monitoring or pathological diagnosis, using FNAC led to the identification of malignancy with a sensitivity of 95.2 % (95%CI: 89.2–97.9%), specificity 84.2% (95%CI: 62.4–94.5%), positive predictive value 97.1% (95%-CI: 91.7–99.0%), negative predictive value 76.2% (95%CI: 54.9–89.4%), likelihoodratio positive 6.03 (95%CI: 2.13–17.05) and accuracy 93.5% (95%CI: 87.7–96.7%). Pneumothorax was the most frequent complication (3 cases). There was good agreement between the cytological findings and the histological findings, not only for malignant lesions (kappa coefficient: 0.641) but also for benign (kappa 0.607).</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">CT-guided percutaneous FNAC is a safe and effective technique for the diagnosis of the mediastinal masses, with a high diagnostic yield for malignancy depicting.</p>" ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<span class="elsevierStyleSectionTitle">Objetivos</span><p class="elsevierStyleSimplePara elsevierViewall">Evaluar la validez diagnóstica de la punción aspiración con aguja fina (PAAF) percutánea en lesiones mediastínicas considerando la biopsia o el seguimiento clínico como patrón de referencia.</p> <span class="elsevierStyleSectionTitle">Pacientes y métodos</span><p class="elsevierStyleSimplePara elsevierViewall">Se realizó PAAF percutánea guiada por TC a 131 pacientes con lesiones mediastínicas. Se usó un TC helicoidal con cortes de 3–10 mm y baja dosis de radiación (40 mAs, 120 kV). Las muestras fueron examinadas in situ por un citólogo para determinar su validez. Se obtuvo comprobación histológica mediante biopsia o estudio de pieza quirúrgica en 73 pacientes y seguimiento clínico en 50, comparándose los resultados globales y en subgrupos.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">En 126 pacientes (96,2%) el material fue válido para diagnóstico. Ciento tres lesiones (78,6%) fueron consideradas malignas (62 tumores primarios y 41 metástasis) y 23 (17,6%) benignas. En los 123 pacientes de los que se dispuso de seguimiento clínico o patológico, la PAAF permitió identificar malignidad con una sensibilidad del 95,2% (IC95%: 89,2–97,9%), especificidad 84,2% (IC95%: 62,4–94,5%), valor predictivo positivo 97,1% (IC95%: 91,7–99,0%), valor predictivo negativo 76,2% (IC95%: 54,9–89,4%), razón de verosi- militud positiva 6,03 (IC95%: 2,13–17,05) y exactitud 93,5% (IC95%: 87,7–96,7%). La complicación más frecuente fue el neumotórax (3 casos). La correlación citohistológica fue elevada tanto en las lesiones malignas (kappa 0,641) como en las benignas (kappa 0,607).</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">La PAAF percutánea guiada por TC es una técnica segura y eficaz para el diagnóstico de masas mediastínicas con alta rentabilidad para la detección de malignidad.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:30 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Usefulness of endoscopic ultrasound-guided fine needle aspiration in the diagnosis of mediastinal lesions" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "G. Fernández-Esparrach" 1 => "M. Pellisé" 2 => "M. Solé" 3 => "J. Belda" 4 => "O. Sendino" 5 => "J. 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| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 6 | 1 | 7 |
| 2024 October | 28 | 15 | 43 |
| 2024 September | 26 | 12 | 38 |
| 2024 August | 42 | 43 | 85 |
| 2024 July | 22 | 23 | 45 |
| 2024 June | 32 | 26 | 58 |
| 2024 May | 43 | 25 | 68 |
| 2024 April | 13 | 20 | 33 |
| 2024 March | 21 | 15 | 36 |
| 2024 February | 18 | 16 | 34 |
| 2023 March | 5 | 3 | 8 |
| 2023 February | 21 | 22 | 43 |
| 2023 January | 13 | 25 | 38 |
| 2022 December | 17 | 25 | 42 |
| 2022 November | 22 | 18 | 40 |
| 2022 October | 18 | 27 | 45 |
| 2022 September | 18 | 26 | 44 |
| 2022 August | 18 | 29 | 47 |
| 2022 July | 19 | 40 | 59 |
| 2022 June | 14 | 40 | 54 |
| 2022 May | 27 | 45 | 72 |
| 2022 April | 20 | 34 | 54 |
| 2022 March | 27 | 48 | 75 |
| 2022 February | 16 | 23 | 39 |
| 2022 January | 20 | 44 | 64 |
| 2021 December | 25 | 55 | 80 |
| 2021 November | 20 | 47 | 67 |
| 2021 October | 22 | 49 | 71 |
| 2021 September | 21 | 53 | 74 |
| 2021 August | 16 | 32 | 48 |
| 2021 July | 12 | 27 | 39 |
| 2021 June | 23 | 43 | 66 |
| 2021 May | 18 | 31 | 49 |
| 2021 April | 21 | 32 | 53 |
| 2021 March | 26 | 31 | 57 |
| 2021 February | 15 | 24 | 39 |
| 2021 January | 12 | 23 | 35 |
| 2020 December | 19 | 27 | 46 |
| 2020 November | 9 | 30 | 39 |
| 2020 October | 23 | 21 | 44 |
| 2020 September | 9 | 13 | 22 |
| 2020 August | 9 | 21 | 30 |
| 2020 July | 16 | 26 | 42 |
| 2020 June | 15 | 14 | 29 |
| 2020 May | 14 | 25 | 39 |
| 2020 April | 19 | 20 | 39 |
| 2020 March | 18 | 13 | 31 |
| 2020 February | 11 | 18 | 29 |
| 2020 January | 21 | 22 | 43 |
| 2019 December | 18 | 20 | 38 |
| 2019 November | 12 | 22 | 34 |
| 2019 October | 12 | 19 | 31 |
| 2019 September | 19 | 33 | 52 |
| 2019 August | 14 | 20 | 34 |
| 2019 July | 15 | 17 | 32 |
| 2019 June | 15 | 14 | 29 |
| 2019 May | 14 | 11 | 25 |
| 2019 April | 41 | 21 | 62 |
| 2019 March | 17 | 58 | 75 |
| 2019 February | 15 | 20 | 35 |
| 2019 January | 8 | 6 | 14 |
| 2018 December | 8 | 16 | 24 |
| 2018 November | 10 | 18 | 28 |
| 2018 October | 8 | 19 | 27 |
| 2018 September | 14 | 15 | 29 |
| 2018 May | 3 | 0 | 3 |
| 2018 April | 9 | 12 | 21 |
| 2018 March | 3 | 7 | 10 |
| 2018 February | 7 | 7 | 14 |
| 2018 January | 6 | 12 | 18 |
| 2017 December | 3 | 17 | 20 |
| 2017 November | 6 | 9 | 15 |
| 2017 October | 10 | 7 | 17 |
| 2017 September | 4 | 8 | 12 |
| 2017 August | 8 | 11 | 19 |
| 2017 July | 15 | 12 | 27 |
| 2017 June | 11 | 17 | 28 |
| 2017 May | 6 | 8 | 14 |
| 2017 April | 4 | 7 | 11 |
| 2017 March | 5 | 20 | 25 |
| 2017 February | 5 | 19 | 24 |
| 2017 January | 3 | 7 | 10 |
| 2016 December | 3 | 9 | 12 |
| 2016 November | 13 | 14 | 27 |
| 2016 October | 11 | 21 | 32 |
| 2016 September | 12 | 30 | 42 |
| 2016 August | 11 | 11 | 22 |
| 2016 July | 7 | 5 | 12 |
| 2016 June | 1 | 0 | 1 |
| 2016 May | 1 | 0 | 1 |
| 2016 April | 1 | 0 | 1 |
| 2016 March | 9 | 0 | 9 |
| 2016 February | 3 | 0 | 3 |
| 2016 January | 7 | 0 | 7 |
| 2015 December | 4 | 0 | 4 |
| 2015 October | 61 | 28 | 89 |
| 2015 September | 54 | 20 | 74 |
| 2015 August | 66 | 17 | 83 |
| 2015 July | 52 | 10 | 62 |
| 2015 June | 49 | 12 | 61 |
| 2015 May | 51 | 20 | 71 |
| 2015 April | 52 | 30 | 82 |
| 2015 March | 35 | 18 | 53 |
| 2015 February | 41 | 14 | 55 |
| 2015 January | 58 | 20 | 78 |
| 2014 December | 111 | 19 | 130 |
| 2014 November | 42 | 15 | 57 |
| 2014 October | 52 | 15 | 67 |
| 2014 September | 50 | 20 | 70 |
| 2014 August | 53 | 19 | 72 |
| 2014 July | 34 | 16 | 50 |
| 2014 June | 55 | 15 | 70 |
| 2014 May | 50 | 19 | 69 |
| 2014 April | 67 | 13 | 80 |
| 2014 March | 73 | 12 | 85 |
| 2014 February | 62 | 21 | 83 |
| 2014 January | 53 | 17 | 70 |
| 2013 December | 53 | 12 | 65 |
| 2013 November | 50 | 5 | 55 |
| 2013 October | 63 | 9 | 72 |
| 2013 September | 47 | 11 | 58 |
| 2013 August | 60 | 10 | 70 |
| 2013 July | 66 | 12 | 78 |
| 2013 June | 39 | 11 | 50 |
| 2013 May | 47 | 8 | 55 |
| 2013 April | 29 | 4 | 33 |
| 2013 March | 11 | 3 | 14 |
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