Original article
Incidence and Characteristics of Asthma Exacerbations in Barcelona (ASMAB II)
Incidencia y características de las agudizaciones asmáticas en Barcelona (ASMAB II)
Ferran Morella,
, Ferran Morellb, Teresa Genoverb, Teresa Genoverc, Esther Benaqued, César Picadob, César Picadoe, Xavier Muñoza, Xavier Muñozb, María Jesús Cruza, María Jesús Cruzb
Corresponding author
a Servei de Pneumologia, Hospital Universitari Vall d’Hebron, Departament de Medicina, Universitat Autònoma de Barcelona, Barcelona, Spain
b CIBER de Enfermedades Respiratorias (CibeRes)
c Centro de Asistencia Primaria Sant Rafael, Barcelona, Spain
d Centro de Asistencia Primaria Río de Janeiro, SAP Muntanya, Institut Català de la Salut, Barcelona, Spain
e Servei de Pneumologia i Al lèrgia Respiratoria, Hospital Clínic, IDIBAPS, Departament de Medicina, Universitat de Barcelona, Barcelona, Spain
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Asistencia Primaria Río de Janeiro, SAP Muntanya, Institut Català de la Salut, Barcelona, Spain" "etiqueta" => "<span class="elsevierStyleSup">d</span>" "identificador" => "aff4" ] 4 => array:3 [ "entidad" => "Servei de Pneumologia i Al lèrgia Respiratoria, Hospital Clínic, IDIBAPS, Departament de Medicina, Universitat de Barcelona, Barcelona, Spain" "etiqueta" => "<span class="elsevierStyleSup">e</span>" "identificador" => "aff5" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Incidencia y características de las agudizaciones asmáticas en Barcelona (ASMAB II)" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2009-04-07" "fechaAceptado" => "2009-06-19" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec155514" "palabras" => array:3 [ 0 => "Bronchial asthma" 1 => "Asthma exacerbations" 2 => "Epidemiology of asthma" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec155513" "palabras" => array:3 [ 0 => "Asma bronquial" 1 => "Exacerbaciones del asma" 2 => "Epidemiología del asma" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<span class="elsevierStyleSectionTitle">Introduction</span><p class="elsevierStyleSimplePara elsevierViewall">A study has been carried out on the incidence and clinical characteristics of asthma exacerbations (AE) seen in hospital accident and emergency departments (HA&ED) and domiciliary services (DS) in Barcelona.</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p class="elsevierStyleSimplePara elsevierViewall">AEs were identified over a 56-day-period during the October and November 2003 and the patients seen in university hospitals were interviewed.</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">A total of 262 AE were identified, 188 in hospital accident and emergency departments and 82 in domiciliary care, which was a mean of 4.6 AE/day, giving an incidence of 0.37 AE/10<span class="elsevierStyleSup">5</span> inhabitants. This incidence was no different from that obtained in the same months in 2002 (<span class="elsevierStyleItalic">P</span> > 0.05). The mean age (±standard deviation) of the143 cases of AE seen in university hospitals was 41±17 years; 87/143 (60%) were women and 57/138 (41%) smokers. In 36/61 (59%) the AE started in the home; in 88/132 (61%) it began 24 hours before arriving at the hospital centre. In 78/123 cases (63%) slow onset of nasal cold was noted before the AE and a viral infection was suspected. Inhaled corticosteroids were administered to 45/112 patients (40%), and only one was also given oral corticosteroids 12 hours before admission. The AEs were mild in 38/75 cases (51%), moderate in 28/75 (37%), severe in 8/75 (11%) and almost fatal in one patient (1.3%). Around 10% (13/137) of patients (10%) were readmitted.</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">The daily incidence of AE is 0.37/10<span class="elsevierStyleSup">5</span> inhabitants. More than half of the exacerbations started after nasal cold and 11% of the AEs were severe.</p>" ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<span class="elsevierStyleSectionTitle">Introducción</span><p class="elsevierStyleSimplePara elsevierViewall">Se ha estudiado la tasa de agudizaciones asmáticas (AA) atendidas en los servicios de urgencias hospitalarios (SUH) y domiciliarios (SEM), así como sus características clínicas.</p> <span class="elsevierStyleSectionTitle">Pacientes y métodos</span><p class="elsevierStyleSimplePara elsevierViewall">Durante los meses de octubre y noviembre de 2003 se identificaron durante 56 días las AA y se entrevistó a los pacientes atendidos en los hospitales universitarios.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Se identificaron 262 AA, 188 en los servicios de urgencias hospitalarios y 82 en los domiciliarios, es decir, una media de 4,6 AA/día, lo que significa una tasa de 0,37 AA/10<span class="elsevierStyleSup">5</span> habitantes, incidencia no diferente de la obtenida en los mismos meses de 2002 (p > 0,05). La edad media (± desviación estándar) de los 143 casos de AA atendidas en los hospitales universitarios era de 41 ± 17 años; 87/143 (60%) eran mujeres y 57/138 (41%), fumadores. En 36/61 (59%) la AA se inició en el domicilio; en 88/132 (61%) comenzó 24 h antes de la llegada al centro hospitalario. En 78/123 casos (63%) se registró catarro nasal de instauración lenta antes de la AA y se sospechó una infección vírica. Recibían corticosteroides inhalados 45/112 pacientes (40%), y únicamente uno añadió corticosteroides orales en las 12h previas al ingreso. La AA era leve en 38/75 casos (51%), moderada en 28/75 (37%), grave en 8/75 (11%) y casi fatal en un paciente (1,3%). Fueron readmitidos 13/137 pacientes (10%).</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">La incidencia diaria de AA es de 0,37/10<span class="elsevierStyleSup">5</span> habitantes. Más de la mitad de las agudizaciones se habían iniciado tras un catarro nasal. Un 11% de las AA eran graves.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:24 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Clinical management of asthma in 1999: the Asthma Insights and Reality in Europe (AIRE) study" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "K.F. Rabe" 1 => "P.A. Vermeire" 2 => "J.B. Soriano" 3 => "W.C. 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| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 4 | 1 | 5 |
| 2024 October | 29 | 37 | 66 |
| 2024 September | 32 | 25 | 57 |
| 2024 August | 46 | 45 | 91 |
| 2024 July | 25 | 22 | 47 |
| 2024 June | 35 | 18 | 53 |
| 2024 May | 39 | 22 | 61 |
| 2024 April | 18 | 22 | 40 |
| 2024 March | 17 | 14 | 31 |
| 2024 February | 28 | 16 | 44 |
| 2023 March | 3 | 0 | 3 |
| 2023 February | 19 | 20 | 39 |
| 2023 January | 22 | 29 | 51 |
| 2022 December | 17 | 35 | 52 |
| 2022 November | 17 | 21 | 38 |
| 2022 October | 27 | 35 | 62 |
| 2022 September | 16 | 20 | 36 |
| 2022 August | 19 | 36 | 55 |
| 2022 July | 22 | 37 | 59 |
| 2022 June | 18 | 37 | 55 |
| 2022 May | 14 | 28 | 42 |
| 2022 April | 13 | 21 | 34 |
| 2022 March | 20 | 43 | 63 |
| 2022 February | 15 | 20 | 35 |
| 2022 January | 17 | 38 | 55 |
| 2021 December | 22 | 60 | 82 |
| 2021 November | 13 | 47 | 60 |
| 2021 October | 49 | 56 | 105 |
| 2021 September | 31 | 59 | 90 |
| 2021 August | 21 | 43 | 64 |
| 2021 July | 24 | 27 | 51 |
| 2021 June | 17 | 35 | 52 |
| 2021 May | 11 | 25 | 36 |
| 2021 April | 22 | 56 | 78 |
| 2021 March | 29 | 26 | 55 |
| 2021 February | 17 | 21 | 38 |
| 2021 January | 15 | 18 | 33 |
| 2020 December | 25 | 15 | 40 |
| 2020 November | 16 | 12 | 28 |
| 2020 October | 4 | 7 | 11 |
| 2020 September | 11 | 5 | 16 |
| 2020 August | 15 | 5 | 20 |
| 2020 July | 15 | 15 | 30 |
| 2020 June | 16 | 2 | 18 |
| 2020 May | 29 | 14 | 43 |
| 2020 April | 18 | 10 | 28 |
| 2020 March | 14 | 8 | 22 |
| 2020 February | 19 | 13 | 32 |
| 2020 January | 12 | 17 | 29 |
| 2019 December | 12 | 12 | 24 |
| 2019 November | 20 | 11 | 31 |
| 2019 October | 18 | 3 | 21 |
| 2019 September | 12 | 9 | 21 |
| 2019 August | 11 | 8 | 19 |
| 2019 July | 11 | 13 | 24 |
| 2019 June | 4 | 6 | 10 |
| 2019 May | 9 | 5 | 14 |
| 2019 April | 6 | 29 | 35 |
| 2019 March | 11 | 12 | 23 |
| 2019 February | 7 | 9 | 16 |
| 2019 January | 4 | 4 | 8 |
| 2018 December | 10 | 15 | 25 |
| 2018 November | 11 | 10 | 21 |
| 2018 October | 25 | 12 | 37 |
| 2018 September | 11 | 12 | 23 |
| 2018 May | 5 | 0 | 5 |
| 2018 April | 5 | 5 | 10 |
| 2018 March | 5 | 5 | 10 |
| 2018 February | 11 | 6 | 17 |
| 2018 January | 3 | 6 | 9 |
| 2017 December | 8 | 6 | 14 |
| 2017 November | 8 | 7 | 15 |
| 2017 October | 6 | 6 | 12 |
| 2017 September | 4 | 7 | 11 |
| 2017 August | 13 | 9 | 22 |
| 2017 July | 11 | 5 | 16 |
| 2017 June | 11 | 10 | 21 |
| 2017 May | 12 | 4 | 16 |
| 2017 April | 5 | 2 | 7 |
| 2017 March | 37 | 5 | 42 |
| 2017 February | 3 | 2 | 5 |
| 2017 January | 3 | 2 | 5 |
| 2016 December | 3 | 5 | 8 |
| 2016 November | 6 | 7 | 13 |
| 2016 October | 9 | 5 | 14 |
| 2016 September | 11 | 5 | 16 |
| 2016 August | 5 | 3 | 8 |
| 2016 July | 6 | 4 | 10 |
| 2016 May | 1 | 0 | 1 |
| 2016 March | 7 | 0 | 7 |
| 2016 February | 7 | 0 | 7 |
| 2016 January | 6 | 0 | 6 |
| 2015 December | 3 | 0 | 3 |
| 2015 October | 37 | 9 | 46 |
| 2015 September | 51 | 6 | 57 |
| 2015 August | 31 | 6 | 37 |
| 2015 July | 37 | 2 | 39 |
| 2015 June | 34 | 5 | 39 |
| 2015 May | 44 | 13 | 57 |
| 2015 April | 27 | 8 | 35 |
| 2015 March | 27 | 12 | 39 |
| 2015 February | 16 | 3 | 19 |
| 2015 January | 30 | 3 | 33 |
| 2014 December | 24 | 2 | 26 |
| 2014 November | 30 | 11 | 41 |
| 2014 October | 50 | 6 | 56 |
| 2014 September | 45 | 7 | 52 |
| 2014 August | 24 | 5 | 29 |
| 2014 July | 30 | 9 | 39 |
| 2014 June | 48 | 3 | 51 |
| 2014 May | 46 | 10 | 56 |
| 2014 April | 57 | 8 | 65 |
| 2014 March | 57 | 4 | 61 |
| 2014 February | 43 | 11 | 54 |
| 2014 January | 40 | 6 | 46 |
| 2013 December | 33 | 11 | 44 |
| 2013 November | 31 | 3 | 34 |
| 2013 October | 32 | 10 | 42 |
| 2013 September | 27 | 5 | 32 |
| 2013 August | 30 | 5 | 35 |
| 2013 July | 54 | 9 | 63 |
| 2013 June | 40 | 6 | 46 |
| 2013 May | 33 | 4 | 37 |
| 2013 April | 11 | 2 | 13 |
| 2013 March | 13 | 3 | 16 |
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