Review article
Chronic Obstructive Pulmonary Disease and Heart Failure
Enfermedad pulmonar obstructiva crónica e insuficiencia cardíaca
Read
7835
Timeswas read the article
2285
Total PDF
5550
Total HTML
Share statistics
array:23 [ "pii" => "S1579212909729374" "issn" => "15792129" "doi" => "10.1016/S1579-2129(09)72937-4" "estado" => "S300" "fechaPublicacion" => "2009-08-01" "aid" => "72937" "copyright" => "Sociedad Española de Neumología y Cirugía Torácica" "copyrightAnyo" => "2009" "documento" => "article" "crossmark" => 0 "subdocumento" => "rev" "cita" => "Arch Bronconeumol. 2009;45:387-93" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 5429 "formatos" => array:3 [ "EPUB" => 102 "HTML" => 4380 "PDF" => 947 ] ] "itemSiguiente" => array:18 [ "pii" => "S1579212909729386" "issn" => "15792129" "doi" => "10.1016/S1579-2129(09)72938-6" "estado" => "S300" "fechaPublicacion" => "2009-08-01" "aid" => "72938" "copyright" => "Sociedad Española de Neumología y Cirugía Torácica" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Arch Bronconeumol. 2009;45:394-404" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1778 "formatos" => array:3 [ "EPUB" => 85 "HTML" => 1157 "PDF" => 536 ] ] "en" => array:9 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Special article</span>" "titulo" => "Postgraduate Training Program in Respiratory Medicine" "tienePdf" => "en" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "394" "paginaFinal" => "404" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Programa de formación posgraduada en neumología" ] ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Felipe Rodríguez de Castro, José Luis Álvarez-Sala, Fernando Sánchez Gascón" "autores" => array:4 [ 0 => array:2 [ "nombre" => "Felipe Rodríguez" "apellidos" => "de Castro" ] 1 => array:2 [ "nombre" => "José Luis" "apellidos" => "Álvarez-Sala" ] 2 => array:2 [ "nombre" => "Fernando Sánchez" "apellidos" => "Gascón" ] 3 => array:1 [ "colaborador" => "other members of the Spanish National Pulmonology Commission (2002 to 2008)" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212909729386?idApp=UINPBA00003Z" "url" => "/15792129/0000004500000008/v1_201305150428/S1579212909729386/v1_201305150428/en/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S1579212909729362" "issn" => "15792129" "doi" => "10.1016/S1579-2129(09)72936-2" "estado" => "S300" "fechaPublicacion" => "2009-08-01" "aid" => "72936" "copyright" => "Sociedad Española de Neumología y Cirugía Torácica" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Arch Bronconeumol. 2009;45:383-6" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 2346 "formatos" => array:3 [ "EPUB" => 111 "HTML" => 1540 "PDF" => 695 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Original article</span>" "titulo" => "Home Mechanical Ventilation: Dependency and Burden of Care in the Home" "tienePdf" => "en" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "383" "paginaFinal" => "386" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Ventilación mecánica domiciliaria: dependencia y carga de cuidados en el domicilio" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Ramón Fernández-Álvarez, Gemma Rubinos-Cuadrado, Cristina Cabrera-Lacalzada, Rosa Galindo-Morales, José Antonio Gullón-Blanco, Isidro González-Martín" "autores" => array:6 [ 0 => array:2 [ "nombre" => "Ramón" "apellidos" => "Fernández-Álvarez" ] 1 => array:2 [ "nombre" => "Gemma" "apellidos" => "Rubinos-Cuadrado" ] 2 => array:2 [ "nombre" => "Cristina" "apellidos" => "Cabrera-Lacalzada" ] 3 => array:2 [ "nombre" => "Rosa" "apellidos" => "Galindo-Morales" ] 4 => array:2 [ "nombre" => "José Antonio" "apellidos" => "Gullón-Blanco" ] 5 => array:2 [ "nombre" => "Isidro" "apellidos" => "González-Martín" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212909729362?idApp=UINPBA00003Z" "url" => "/15792129/0000004500000008/v1_201305150428/S1579212909729362/v1_201305150428/en/main.assets" ] "en" => array:15 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Review article</span>" "titulo" => "Chronic Obstructive Pulmonary Disease and Heart Failure" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "387" "paginaFinal" => "393" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Felipe Villar Álvarez, Manuel Méndez Bailón, Javier de Miguel Díez" "autores" => array:3 [ 0 => array:3 [ "nombre" => "Felipe Villar" "apellidos" => "Álvarez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 1 => array:3 [ "nombre" => "Manuel Méndez" "apellidos" => "Bailón" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] ] 2 => array:4 [ "nombre" => "Javier de Miguel" "apellidos" => "Díez" "email" => array:1 [ 0 => "jmiguel.hgugm@salud.madrid.org" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff3" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor1" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Servicio de Neumología, Fundación Jiménez Díaz - CAPIO, Madrid, Spain" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:3 [ "entidad" => "Servicio de Medicina Interna, Hospital Infanta Leonor, Madrid, Spain" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] 2 => array:3 [ "entidad" => "Servicio de Neumología, Hospital General Universitario Gregorio Marañón, Universidad Complutense de Madrid. Madrid, Spain" "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff3" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Enfermedad pulmonar obstructiva crónica e insuficiencia cardíaca" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2008-02-25" "fechaAceptado" => "2008-05-29" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec155787" "palabras" => array:5 [ 0 => "Chronic obstructive pulmonary disease" 1 => "Heart failure" 2 => "Biological markers" 3 => "Pharmacological treatment" 4 => "Nonpharmacological treatment" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec155786" "palabras" => array:5 [ 0 => "Enfermedad pulmonar obstructiva crónica" 1 => "Insuficiencia cardíaca" 2 => "Marcadores biológicos" 3 => "Tratamiento farmacológico" 4 => "Tratamientos no farmacológicos" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">Chronic obstructive pulmonary disease (COPD) is commonly associated with heart failure. Individuals with COPD have a 4.5-fold greater risk of developing heart failure than those without. The sensitivity and specificity of clinical judgment in the diagnosis of heart failure in patients with COPD can be enhanced by biological markers such as B-type natriuretic peptide and N-terminal pro-B-type natriuretic peptide. Correct interpretation of imaging results (mainly echocardiographic findings) and lung function tests can also help establish the co-occurrence of both conditions. There is little evidence on the management of patients with COPD and heart failure, although treatment of COPD undeniably affects the clinical course of patients with heart failure and viceversa.</p>" ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">La enfermedad pulmonar obstructiva crónica (EPOC) es una enfermedad frecuentemente asociada a la insuficiencia cardíaca (IC). El riesgo de desarrollar IC en los pacientes con EPOC es 4,5 veces superior al de los sujetos sin este trastorno. Distintos marcadores biológicos, entre los que se encuentran el péptido natriurético tipo B y el fragmento N-terminal del propétpido natriurético tipo B, pueden aumentar la sensibilidad y la especificidad del propio juicio clínico a la hora de establecer el diagnóstico de IC en los pacientes con EPOC. La interpretación correcta de las técnicas de imagen (fundamentalmente el ecocardiograma) y de las pruebas de función pulmonar puede ayudar también a diagnosticar la concurrencia de ambos procesos. Existen pocas evidencias acerca del tratamiento combinado de la EPOC y la IC. Lo que es incuestionable es que el tratamiento de la EPOC puede influir en la evolución clínica de la IC, y viceversa.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:71 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Diagnostic and therapeutic challenges in patients with coexistent chronic obstructive pulmonary disease and chronic heart failure" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "T.H. Le Jemtel" 1 => "M. Padeletti" 2 => "S. Jelic" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.jacc.2006.08.046" "Revista" => array:6 [ "tituloSerie" => "J Am Coll Cardiol" "fecha" => "2007" "volumen" => "49" "paginaInicial" => "171" "paginaFinal" => "180" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17222727" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Managed care and outcomes of hospitalization among elderly patients with congestive heart failure" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "H. Ni" 1 => "D. Nauman" 2 => "R.E. Hershberger" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Arch Int Med" "fecha" => "1998" "volumen" => "158" "paginaInicial" => "1231" "paginaFinal" => "1236" ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib3" "etiqueta" => "3." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cardiovascular disease in patients with chronic obstructive pulmonary disease, Saskatchewan Canada cardiovascular disease in COPD patients" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "S.M. Curkendall" 1 => "C. DeLuise" 2 => "J.K. Jones" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.annepidem.2005.04.008" "Revista" => array:6 [ "tituloSerie" => "Ann Epidemiol" "fecha" => "2006" "volumen" => "16" "paginaInicial" => "63" "paginaFinal" => "70" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16039877" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib4" "etiqueta" => "4." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Impaired lung function and mortality risk in men and women: findings from the Renfrew and Paisley prospective population study" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "D.J. Hole" 1 => "G.C. Watt" 2 => "G. Davey-Smith" 3 => "C.L. Hart" 4 => "C.R. Gillis" 5 => "V.M. Hawthorne" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "BMJ" "fecha" => "1996" "volumen" => "313" "paginaInicial" => "711" "paginaFinal" => "715" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8819439" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib5" "etiqueta" => "5." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) workshop summary" "autores" => array:1 [ 0 => array:3 [ "colaboracion" => "GOLD Scientific Committee" "etal" => false "autores" => array:5 [ 0 => "R.A. Pauwels" 1 => "A.S. Buist" 2 => "P.M. Calverley" 3 => "C.R. Jenkins" 4 => "S.S. Hurd" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/ajrccm.163.5.2101039" "Revista" => array:6 [ "tituloSerie" => "Am J Respir Crit Care Med" "fecha" => "2001" "volumen" => "163" "paginaInicial" => "1256" "paginaFinal" => "1276" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11316667" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib6" "etiqueta" => "6." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The prognostic influence of chronic obstructive pulmonary disease in patients hospitalised for chronic heart failure" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "A. Macchia" 1 => "S. Monte" 2 => "M. Romero" 3 => "A. D’Ettorre" 4 => "G. Tognoni" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.ejheart.2007.06.004" "Revista" => array:6 [ "tituloSerie" => "Eur J Heart Fail" "fecha" => "2007" "volumen" => "9" "paginaInicial" => "942" "paginaFinal" => "948" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17627878" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib7" "etiqueta" => "7." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Are patients with chronic obstructive pulmonary disease at increased risk of cardiovascular morbidity and mortality?" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "D.D. Sin" 1 => "J. Hogg" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1002/nbm.3282" "Revista" => array:6 [ "tituloSerie" => "CVR&R" "fecha" => "2004" "volumen" => "25" "paginaInicial" => "168" "paginaFinal" => "170" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25788020" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib8" "etiqueta" => "8." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Why are patients with chronic obstructive pulmonary disease at increased risk of cardiovascular diseases? The potential role of systemic inflammation in chronic obstructive pulmonary disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "D.D. Sin" 1 => "S.F. Man" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Circulation" "fecha" => "2003" "volumen" => "107" "paginaInicial" => "1514" "paginaFinal" => "1519" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12654609" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib9" "etiqueta" => "9." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Left ventricular ejection fraction in severe chronic obstructive airways disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "P. Steele" 1 => "J.H. Ellis" 2 => "D. van Dyke" 3 => "F. Sutton" 4 => "E. Creagh" 5 => "H. Davies" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Med" "fecha" => "1975" "volumen" => "59" "paginaInicial" => "21" "paginaFinal" => "28" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1138548" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib10" "etiqueta" => "10." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Striking similarities in systemic factors contributing to decreased exercise capacity in patients with severe chronic heart failure or COPD" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "H.R. Gosker" 1 => "N.H. Lencer" 2 => "F.M. Franssen" 3 => "G.J. van der Vusse" 4 => "E.F. Wouters" 5 => "A.M. Schols" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "2003" "volumen" => "123" "paginaInicial" => "1416" "paginaFinal" => "1424" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12740256" "web" => "Medline" ] ] ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib11" "etiqueta" => "11." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Skeletal muscle dysfunction in chronic obstructive pulmonary disease and chronic heart failure: underlying mechanisms and therapy perspectives" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "H.R. Gosker" 1 => "E.F. Wouters" 2 => "G.J. van der Vusse" 3 => "A.M. Schols" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Clin Nutr" "fecha" => "2000" "volumen" => "71" "paginaInicial" => "1033" "paginaFinal" => "1047" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10799364" "web" => "Medline" ] ] ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib12" "etiqueta" => "12." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Active skeletal muscle mass and cardiopulmonary reserve. Failure to attain peak aerobic capacity during maximal bicycle exercise in patients with severe congestive heart failure" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "G. Jondeau" 1 => "S.D. Katz" 2 => "L. Zohman" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Circulation" "fecha" => "1992" "volumen" => "86" "paginaInicial" => "1351" "paginaFinal" => "1356" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1423946" "web" => "Medline" ] ] ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib13" "etiqueta" => "13." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Skeletal muscle function and its relation to exercise tolerance in chronic heart failure" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "D. Harrington" 1 => "S.D. Anker" 2 => "T.P. Chua" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Am Coll Cardiol" "fecha" => "1997" "volumen" => "30" "paginaInicial" => "1758" "paginaFinal" => "1764" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9385904" "web" => "Medline" ] ] ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib14" "etiqueta" => "14." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The molecular basis of skeletal muscle atrophy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "R.W. Jackman" 1 => "S.C. Kandarian" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1152/ajpcell.00579.2003" "Revista" => array:6 [ "tituloSerie" => "Am J Physiol Cell Physiol" "fecha" => "2004" "volumen" => "287" "paginaInicial" => "C834" "paginaFinal" => "C843" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15355854" "web" => "Medline" ] ] ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib15" "etiqueta" => "15." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Association between chronic obstructive pulmonary disease and systemic inflammation: a systematic review and a metaanalysis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "W.Q. Gan" 1 => "S.F. Man" 2 => "A. Senthilselvan" 3 => "D.D. Sin" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Thorax" "fecha" => "2004" "volumen" => "59" "paginaInicial" => "574" "paginaFinal" => "580" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15223864" "web" => "Medline" ] ] ] ] ] ] ] ] 15 => array:3 [ "identificador" => "bib16" "etiqueta" => "16." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Plasma A- and B-type natriuretic peptides: physiology, methodology and clinical use" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "F. Boomama" 1 => "A.H. van der Meiracker" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Cardiovasc Res" "fecha" => "2001" "volumen" => "51" "paginaInicial" => "442" "paginaFinal" => "449" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11476734" "web" => "Medline" ] ] ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bib17" "etiqueta" => "17." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Rapid measurement of B-type natriuretic peptide in the emergency diagnosis of heart failure" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "A.S. Maisel" 1 => "P. Krishnaswamy" 2 => "R.M. Nowak" 3 => "J. McCord" 4 => "J.E. Hollander" 5 => "P. Duc" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1056/NEJMoa020233" "Revista" => array:6 [ "tituloSerie" => "N Engl J Med" "fecha" => "2002" "volumen" => "347" "paginaInicial" => "161" "paginaFinal" => "167" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12124404" "web" => "Medline" ] ] ] ] ] ] ] ] 17 => array:3 [ "identificador" => "bib18" "etiqueta" => "18." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "NT-proBNP testing for diagnosis and short-term prognosis in acute destabilized heart failure: an international pooled analysis of 1256 patients: the international collaborative of NT-proBNP study" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "J.L. Januzzi" 1 => "R. van Kimmenade" 2 => "J. Lainchbury" 3 => "A. Bayes-Genis" 4 => "J. Ordonez-Llanos" 5 => "M. Santalo-Bel" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1093/eurheartj/ehi631" "Revista" => array:6 [ "tituloSerie" => "Eur Heart J" "fecha" => "2006" "volumen" => "27" "paginaInicial" => "330" "paginaFinal" => "337" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16293638" "web" => "Medline" ] ] ] ] ] ] ] ] 18 => array:3 [ "identificador" => "bib19" "etiqueta" => "19." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Unrecognized heart failure in elderly patients with stable chronic obstructive pulmonary disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "F. Rutten" 1 => "M. Cramer" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1093/eurheartj/ehi291" "Revista" => array:6 [ "tituloSerie" => "Eur Heart J" "fecha" => "2005" "volumen" => "26" "paginaInicial" => "1887" "paginaFinal" => "1894" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15860516" "web" => "Medline" ] ] ] ] ] ] ] ] 19 => array:3 [ "identificador" => "bib20" "etiqueta" => "20." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Obesity and suppressed B-type natriuretic peptide levels in heart failure" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "M.R. Mehra" 1 => "P.A. Uber" 2 => "M.H. Park" 3 => "R.L. Scott" 4 => "H.O. Ventura" 5 => "B.C. Harris" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.jacc.2003.10.066" "Revista" => array:6 [ "tituloSerie" => "J Am Coll Cardiol" "fecha" => "2004" "volumen" => "43" "paginaInicial" => "1590" "paginaFinal" => "1595" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15120816" "web" => "Medline" ] ] ] ] ] ] ] ] 20 => array:3 [ "identificador" => "bib21" "etiqueta" => "21." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Expression of natriuretic peptide receptors in human adipose and other tissues" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "R. Sarzani" 1 => "P. Dessi-Fulgheri" 2 => "V.M. Paci" 3 => "E. Espinosa" 4 => "A. Rappelli" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Endocrinol Invest" "fecha" => "1996" "volumen" => "19" "paginaInicial" => "581" "paginaFinal" => "585" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8957740" "web" => "Medline" ] ] ] ] ] ] ] ] 21 => array:3 [ "identificador" => "bib22" "etiqueta" => "22." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "B-type natriuretic peptide and renal function in the diagnosis of heart failure: an analysis from the Breathing Not Properly Multinational Study" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "P.A. McCullough" 1 => "P. Duc" 2 => "T. Omland" 3 => "J. McCord" 4 => "R.M. Nowak" 5 => "J.E. Hollander" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1053/ajkd.2003.50118" "Revista" => array:6 [ "tituloSerie" => "Am J Kidney Dis" "fecha" => "2003" "volumen" => "41" "paginaInicial" => "571" "paginaFinal" => "579" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12612980" "web" => "Medline" ] ] ] ] ] ] ] ] 22 => array:3 [ "identificador" => "bib23" "etiqueta" => "23." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Determinación del fragmento N-terminal del propéptido natriurético cerebral (NTproBNP) en pacientes de edad avanzada con disnea aguda: valor diagnóstico y pronóstico" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "M. Méndez-Bailón" 1 => "N. Muñoz-Rivas" 2 => "C. Romero Román" 3 => "C. Pérez de Oteyza" 4 => "P. Conthe Gutiérrez" 5 => "L. Audibert Mena" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Med Clin (Barc)" "fecha" => "2007" "volumen" => "12" "paginaInicial" => "453" "paginaFinal" => "455" ] ] ] ] ] ] 23 => array:3 [ "identificador" => "bib24" "etiqueta" => "24." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "C-reactive protein and interleukin-6 in vascular disease: culprits or passive bystanders?" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "M. Rattazzi" 1 => "M. Puato" 2 => "E. Faggin" 3 => "B. Bertipaglia" 4 => "A. Zambon" 5 => "P. Pauletto" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/01.hjh.0000084735.53355.44" "Revista" => array:6 [ "tituloSerie" => "J Hypertens" "fecha" => "2003" "volumen" => "21" "paginaInicial" => "1787" "paginaFinal" => "1803" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14508181" "web" => "Medline" ] ] ] ] ] ] ] ] 24 => array:3 [ "identificador" => "bib25" "etiqueta" => "25." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Function of C-reactive protein" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "T.W. du Clos" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Ann Med" "fecha" => "2000" "volumen" => "32" "paginaInicial" => "274" "paginaFinal" => "278" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10852144" "web" => "Medline" ] ] ] ] ] ] ] ] 25 => array:3 [ "identificador" => "bib26" "etiqueta" => "26." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "P.M. Ridker" 1 => "N. Rifai" 2 => "L. Rose" 3 => "J.E. Buring" 4 => "N.R. Cook" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1056/NEJMoa021993" "Revista" => array:6 [ "tituloSerie" => "N Engl J Med" "fecha" => "2002" "volumen" => "347" "paginaInicial" => "1557" "paginaFinal" => "1565" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12432042" "web" => "Medline" ] ] ] ] ] ] ] ] 26 => array:3 [ "identificador" => "bib27" "etiqueta" => "27." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "C-reactive protein elevation and disease activity in patients with coronary artery disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "R. Arroyo Espliguero" 1 => "P. Avanzas" 2 => "J. Cosin Sales" 3 => "G. Aldama" 4 => "C. Pizzi" 5 => "J.C. Kaski" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.ehj.2003.12.017" "Revista" => array:6 [ "tituloSerie" => "Eur Heart J" "fecha" => "2004" "volumen" => "25" "paginaInicial" => "401" "paginaFinal" => "408" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15033252" "web" => "Medline" ] ] ] ] ] ] ] ] 27 => array:3 [ "identificador" => "bib28" "etiqueta" => "28." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "C-reactive protein modulates risk prediction based on the Framingham score: implications for future risk assessment: results from a large cohort study in southern Germany" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "W. Koenig" 1 => "H. Lowel" 2 => "J. Baumert" 3 => "C. Meisinger" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1161/01.CIR.0000120707.98922.E3" "Revista" => array:6 [ "tituloSerie" => "Circulation" "fecha" => "2004" "volumen" => "109" "paginaInicial" => "1349" "paginaFinal" => "1353" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15023871" "web" => "Medline" ] ] ] ] ] ] ] ] 28 => array:3 [ "identificador" => "bib29" "etiqueta" => "29." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Adipose tissue, adipokines, and inflammation" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "G. Fantuzzi" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.jaci.2005.02.023" "Revista" => array:6 [ "tituloSerie" => "J Allergy Clin Immunol" "fecha" => "2005" "volumen" => "115" "paginaInicial" => "911" "paginaFinal" => "919" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15867843" "web" => "Medline" ] ] ] ] ] ] ] ] 29 => array:3 [ "identificador" => "bib30" "etiqueta" => "30." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Differences in interleukin-8 and tumor necrosis factor-alpha in induced sputum from patients with chronic obstructive pulmonary disease or asthma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "V.M. Keatings" 1 => "P.D. Collins" 2 => "D.M. Scott" 3 => "P.J. Barnes" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/ajrccm.153.2.8564092" "Revista" => array:6 [ "tituloSerie" => "Am J Respir Crit Care Med" "fecha" => "1996" "volumen" => "153" "paginaInicial" => "530" "paginaFinal" => "534" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8564092" "web" => "Medline" ] ] ] ] ] ] ] ] 30 => array:3 [ "identificador" => "bib31" "etiqueta" => "31." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Exhaled markers of pulmonary disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "S.A. Kharitonov" 1 => "P. Barnes" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Am J Crit Care Med" "fecha" => "2001" "volumen" => "163" "paginaInicial" => "1693" "paginaFinal" => "1722" ] ] ] ] ] ] 31 => array:3 [ "identificador" => "bib32" "etiqueta" => "32." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The genetics of chronic obstructive pulmonary disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "A.M. Wood" 1 => "R.A. Stockley" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1186/1465-9921-7-130" "Revista" => array:6 [ "tituloSerie" => "Respir Res" "fecha" => "2006" "volumen" => "7" "paginaInicial" => "130" "paginaFinal" => "144" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17054776" "web" => "Medline" ] ] ] ] ] ] ] ] 32 => array:3 [ "identificador" => "bib33" "etiqueta" => "33." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Skeletal muscle metabolites and fiber types in patients with advanced chronic obstructive pulmonary disease (COPD), with and without chronic respiratory failure" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "P. Jakobsson" 1 => "L. Jorfeldt" 2 => "A. Brundin" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Eur Respir J" "fecha" => "1990" "volumen" => "3" "paginaInicial" => "192" "paginaFinal" => "196" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2311744" "web" => "Medline" ] ] ] ] ] ] ] ] 33 => array:3 [ "identificador" => "bib34" "etiqueta" => "34." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The limited reliability of physical signs for estimating hemodynamics in chronic heart failure" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "L. Stevenson" 1 => "J. Perloff" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "JAMA" "fecha" => "1989" "volumen" => "261" "paginaInicial" => "884" "paginaFinal" => "888" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2913385" "web" => "Medline" ] ] ] ] ] ] ] ] 34 => array:3 [ "identificador" => "bib35" "etiqueta" => "35." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Value of ECGs in identifying heart failure due to left ventricular systolic dysfunction" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "A.P. Davie" 1 => "J.J. McMurray" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "BMJ" "fecha" => "1996" "volumen" => "313" "paginaInicial" => "300" "paginaFinal" => "301" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8704562" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0212656711000941" "estado" => "S300" "issn" => "02126567" ] ] ] ] ] ] ] 35 => array:3 [ "identificador" => "bib36" "etiqueta" => "36." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "B type natriuretic peptide in cardiovascular disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "J.A. de Lemos" 1 => "D.K. McGuire" 2 => "M.H. Drazner" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/S0140-6736(03)13976-1" "Revista" => array:6 [ "tituloSerie" => "Lancet" "fecha" => "2003" "volumen" => "362" "paginaInicial" => "316" "paginaFinal" => "322" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12892964" "web" => "Medline" ] ] ] ] ] ] ] ] 36 => array:3 [ "identificador" => "bib37" "etiqueta" => "37." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Breathing not properly multinational study investigators. B-type natriuretic peptide and renal function in the diagnosis of heart failure: an analysis from the Breathing Not Properly Multinational Study" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "P.A. McCullough" 1 => "P. Duc" 2 => "T. Omland" 3 => "J. McCord" 4 => "R.M. Nowak" 5 => "J.E. Hollander" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1053/ajkd.2003.50118" "Revista" => array:6 [ "tituloSerie" => "Am J Kidney Dis" "fecha" => "2003" "volumen" => "41" "paginaInicial" => "571" "paginaFinal" => "579" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12612980" "web" => "Medline" ] ] ] ] ] ] ] ] 37 => array:3 [ "identificador" => "bib38" "etiqueta" => "38." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Natriuretic peptides, respiratory disease, and the right heart" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "L.B. Yap" 1 => "D. Mukerjee" 2 => "P. Timms" 3 => "H. Ashrafian" 4 => "J.G. Coghlan" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1378/chest.126.4.1330" "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "2004" "volumen" => "126" "paginaInicial" => "1330" "paginaFinal" => "1336" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15486400" "web" => "Medline" ] ] ] ] ] ] ] ] 38 => array:3 [ "identificador" => "bib39" "etiqueta" => "39." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Left ventricular dysfunction in deteriorating patients with chronic obstructive pulmonary disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "M.L. Render" 1 => "A.S. Weinstein" 2 => "A.S. Blaustein" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "1995" "volumen" => "107" "paginaInicial" => "162" "paginaFinal" => "168" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7813269" "web" => "Medline" ] ] ] ] ] ] ] ] 39 => array:3 [ "identificador" => "bib40" "etiqueta" => "40." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pulmonary hypertension and right ventricular function in patients with COPD" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "W. Biernacki" 1 => "D.C. Flenley" 2 => "A.L. Muir" 3 => "W. MacNee" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Chest" "fecha" => "1988" "volumen" => "94" "paginaInicial" => "1169" "paginaFinal" => "1175" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3191757" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0140673604162570" "estado" => "S300" "issn" => "01406736" ] ] ] ] ] ] ] 40 => array:3 [ "identificador" => "bib41" "etiqueta" => "41." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Recommendations concerning use of echocardiography in hypertension and general population research" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "R.B. Devereaux" 1 => "P.R. Liebson" 2 => "M.J. Horan" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Hypertension" "fecha" => "1987" "volumen" => "9" "paginaInicial" => "935" "paginaFinal" => "970" ] ] ] ] ] ] 41 => array:3 [ "identificador" => "bib42" "etiqueta" => "42." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Striking similarities in systemic factors contributing to decreased exercise capacity in patients with severe chronic heart failure or COPD" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "H.R. Gosker" 1 => "N.H. Lencer" 2 => "F.M. Franssen" 3 => "G.J. van der Vusse" 4 => "E.F. Wouters" 5 => "A.M. Schols" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "2003" "volumen" => "123" "paginaInicial" => "1416" "paginaFinal" => "1424" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12740256" "web" => "Medline" ] ] ] ] ] ] ] ] 42 => array:3 [ "identificador" => "bib43" "etiqueta" => "43." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Insuficiencia cardiaca y enfermedad pulmonar obstructiva crónica" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "J. Navarro Esteva" 1 => "B. Alonso" ] ] ] ] ] "host" => array:2 [ 0 => array:1 [ "Revista" => array:3 [ "tituloSerie" => "Arch Med" "fecha" => "2005" "volumen" => "1" ] ] 1 => array:1 [ "WWW" => array:1 [ "link" => "www.archivosdemedicina.com" ] ] ] ] ] ] 43 => array:3 [ "identificador" => "bib44" "etiqueta" => "44." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Beta-blockers in chronic heart failure" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "M. Gheorghiade" 1 => "W.S. Colucci" 2 => "K. Swedberg" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1161/01.CIR.0000065187.80707.18" "Revista" => array:6 [ "tituloSerie" => "Circulation" "fecha" => "2003" "volumen" => "107" "paginaInicial" => "1570" "paginaFinal" => "1575" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12668487" "web" => "Medline" ] ] ] ] ] ] ] ] 44 => array:3 [ "identificador" => "bib45" "etiqueta" => "45." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cardioselective beta-blockers in patients with reactive airway disease: a meta-analysis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "S.R. Salpeter" 1 => "T.M. Ormiston" 2 => "E.E. Salpeter" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Ann Intern Med" "fecha" => "2002" "volumen" => "137" "paginaInicial" => "715" "paginaFinal" => "725" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12416945" "web" => "Medline" ] ] ] ] ] ] ] ] 45 => array:3 [ "identificador" => "bib46" "etiqueta" => "46." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Reduction of morbidity and mortality by statins, angiotensinconverting enzyme inhibitors, and angiotensin receptor blockers in patients with chronic obstructive pulmonary disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "G.B. Mancini" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.jacc.2006.04.039" "Revista" => array:6 [ "tituloSerie" => "J Am Coll Cardiol" "fecha" => "2006" "volumen" => "47" "paginaInicial" => "2554" "paginaFinal" => "2560" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16781387" "web" => "Medline" ] ] ] ] ] ] ] ] 46 => array:3 [ "identificador" => "bib47" "etiqueta" => "47." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Meta-analyses of mortality and morbidity effects of an angiotensin receptor blocker in patients with chronic heart failure already receiving an ACE inhibitor (alone or with a beta-blocker)" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "K. Dimopoulos" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.ijcard.2003.10.001" "Revista" => array:6 [ "tituloSerie" => "Int J Cardiol" "fecha" => "2004" "volumen" => "93" "paginaInicial" => "105" "paginaFinal" => "111" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14975535" "web" => "Medline" ] ] ] ] ] ] ] ] 47 => array:3 [ "identificador" => "bib48" "etiqueta" => "48." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Treatment of heart failure in older persons. Dilemmas with coexisting conditions: diabetes mellitus, chronic obstructive pulmonary disease, and arthritis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "W.S. Aronow" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Congest Heart Fail" "fecha" => "2003" "volumen" => "9" "paginaInicial" => "142" "paginaFinal" => "147" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12826772" "web" => "Medline" ] ] ] ] ] ] ] ] 48 => array:3 [ "identificador" => "bib49" "etiqueta" => "49." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Relation of loop diuretic dose to mortality in advanced heart failure" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "M. Eshaghian" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.amjcard.2005.12.072" "Revista" => array:6 [ "tituloSerie" => "Am J Cardiol" "fecha" => "2006" "volumen" => "97" "paginaInicial" => "1759" "paginaFinal" => "1764" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16765130" "web" => "Medline" ] ] ] ] ] ] ] ] 49 => array:3 [ "identificador" => "bib50" "etiqueta" => "50." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Risk of mortality and heart failure exacerbations associated with inhaled beta-adrenoceptor agonists among patients with known left ventricular systolic dysfunction" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "D.H. Au" 1 => "E.M. Udris" 2 => "V.S. Fan" 3 => "J.R. Curtis" 4 => "M.B. McDonell" 5 => "S.D. Fihn" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "2003" "volumen" => "123" "paginaInicial" => "1964" "paginaFinal" => "1969" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12796175" "web" => "Medline" ] ] ] ] ] ] ] ] 50 => array:3 [ "identificador" => "bib51" "etiqueta" => "51." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Left ventricular diastolic dysfunction in patients with bronchial asthma with long-term oral beta2-adrenoceptor agonists" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "O. Hirono" 1 => "I. Kubota" 2 => "O. Minamihaba" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1067/mhj.2001.118117" "Revista" => array:6 [ "tituloSerie" => "Am Heart J" "fecha" => "2001" "volumen" => "142" "paginaInicial" => "E11" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11717622" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0014256510005199" "estado" => "S300" "issn" => "00142565" ] ] ] ] ] ] ] 51 => array:3 [ "identificador" => "bib52" "etiqueta" => "52." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A long-term evaluation of once-daily inhaled tiotropium in chronic obstructive pulmonary disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "R. Casaburi" 1 => "D.A. Mahler" 2 => "P.W. Jones" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Eur Respir J" "fecha" => "2002" "volumen" => "19" "paginaInicial" => "217" "paginaFinal" => "224" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11866001" "web" => "Medline" ] ] ] ] ] ] ] ] 52 => array:3 [ "identificador" => "bib53" "etiqueta" => "53." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Use of oral glucocorticoids and risk of cardiovascular and cerebrovascular disease in a population based case-control study" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "D.C. Souverein" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1136/hrt.2003.020180" "Revista" => array:6 [ "tituloSerie" => "Heart" "fecha" => "2004" "volumen" => "90" "paginaInicial" => "859" "paginaFinal" => "865" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15253953" "web" => "Medline" ] ] ] ] ] ] ] ] 53 => array:3 [ "identificador" => "bib54" "etiqueta" => "54." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pulmonary hypertension in chronic obstructive pulmonary disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "J.A. Barbera" 1 => "V.I. Peinado" 2 => "S. Santos" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Eur Respir J" "fecha" => "2003" "volumen" => "21" "paginaInicial" => "892" "paginaFinal" => "905" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12765440" "web" => "Medline" ] ] ] ] ] ] ] ] 54 => array:3 [ "identificador" => "bib55" "etiqueta" => "55." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Severe pulmonary hypertension in COPD: is it a distinct disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "E. Weitzenblum" 1 => "A. Chaouat" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1378/chest.127.5.1480" "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "2005" "volumen" => "127" "paginaInicial" => "1480" "paginaFinal" => "1482" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15888814" "web" => "Medline" ] ] ] ] ] ] ] ] 55 => array:3 [ "identificador" => "bib56" "etiqueta" => "56." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Factors contributing to the reversible pulmonary hypertension of patients with acute respiratory failure studied by serial observations during recovery" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "A.S. Abraham" 1 => "R.B. Cole" 2 => "I.D. Green" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Circ Res" "fecha" => "1969" "volumen" => "24" "paginaInicial" => "51" "paginaFinal" => "60" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5763739" "web" => "Medline" ] ] ] ] ] ] ] ] 56 => array:3 [ "identificador" => "bib57" "etiqueta" => "57." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Right ventricular function and pulmonary hemodynamics during exercise in patients with chronic obstructive bronchopulmonary disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "V. Jezek" 1 => "F. Schrijen" 2 => "P. Sadoul" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Cardiology" "fecha" => "1973" "volumen" => "58" "paginaInicial" => "20" "paginaFinal" => "31" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4710797" "web" => "Medline" ] ] ] ] ] ] ] ] 57 => array:3 [ "identificador" => "bib58" "etiqueta" => "58." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cardiopulmonary hemodynamics during sleep in subjects with chronic obstructive pulmonary disease: the effect of short and long term oxygen" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "E.C. Fletcher" 1 => "D.C. Levin" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "1984" "volumen" => "85" "paginaInicial" => "6" "paginaFinal" => "14" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6690253" "web" => "Medline" ] ] ] ] ] ] ] ] 58 => array:3 [ "identificador" => "bib59" "etiqueta" => "59." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pulmonary hemodynamics in advanced COPD candidates for lung volume reduction surgery or lung transplantation" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "G. Thabut" 1 => "G. Dauriat" 2 => "J.B. Stern" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1378/chest.127.5.1531" "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "2005" "volumen" => "127" "paginaInicial" => "1531" "paginaFinal" => "1536" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15888824" "web" => "Medline" ] ] ] ] ] ] ] ] 59 => array:3 [ "identificador" => "bib60" "etiqueta" => "60." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Sildenafil improves hemodynamic parameters in COPD - An investigation of six patients" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "S. Alp" 1 => "M. Skrygan" 2 => "W.E. Schmidt" 3 => "A. Bastian" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.pupt.2005.09.006" "Revista" => array:6 [ "tituloSerie" => "Pulm Pharmacol Ther" "fecha" => "2006" "volumen" => "19" "paginaInicial" => "386" "paginaFinal" => "390" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16291503" "web" => "Medline" ] ] ] ] ] ] ] ] 60 => array:3 [ "identificador" => "bib61" "etiqueta" => "61." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Long-term oxygen therapy can reverse the progression of pulmonary hypertension in patients with chronic obstructive pulmonary disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "E. Weitzenblum" 1 => "A. Sautegeau" 2 => "M. Ehrhart" 3 => "M. Mammosser" 4 => "A. Pelletier" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/arrd.1985.131.4.493" "Revista" => array:6 [ "tituloSerie" => "Am Rev Respir Dis" "fecha" => "1985" "volumen" => "131" "paginaInicial" => "493" "paginaFinal" => "498" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3922267" "web" => "Medline" ] ] ] ] ] ] ] ] 61 => array:3 [ "identificador" => "bib62" "etiqueta" => "62." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effects of removing oxygen from patients with chronic obstructive pulmonary disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "S.R. Selinger" 1 => "T.P. Kennedy" 2 => "P. Buescher" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/ajrccm/136.1.85" "Revista" => array:6 [ "tituloSerie" => "Am Rev Respir Dis" "fecha" => "1987" "volumen" => "136" "paginaInicial" => "85" "paginaFinal" => "91" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3605848" "web" => "Medline" ] ] ] ] ] ] ] ] 62 => array:3 [ "identificador" => "bib63" "etiqueta" => "63." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pulmonary circulation" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "R. Naeije" 1 => "W. MacNee" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:5 [ "titulo" => "Chronic obstructive pulmonary disease" "paginaInicial" => "228" "paginaFinal" => "242" "edicion" => "2nd ed." "serieFecha" => "2003" ] ] ] ] ] ] 63 => array:3 [ "identificador" => "bib64" "etiqueta" => "64." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pulmonary Hypertension and right heart failure in chronic obstructive pulmonary disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "R. Naeije" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1513/pats.200407-037MS" "Revista" => array:6 [ "tituloSerie" => "Proc Am Thorac Soc" "fecha" => "2005" "volumen" => "2" "paginaInicial" => "20" "paginaFinal" => "22" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16113464" "web" => "Medline" ] ] ] ] ] ] ] ] 64 => array:3 [ "identificador" => "bib65" "etiqueta" => "65." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Should pulmonary hypertension be treated in chronic obstructive pulmonary disease?" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "R. Naeije" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:4 [ "titulo" => "The diagnosis and treatment of pulmonary hypertension" "paginaInicial" => "209" "paginaFinal" => "239" "serieFecha" => "1992" ] ] ] ] ] ] 65 => array:3 [ "identificador" => "bib66" "etiqueta" => "66." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Ventilación mecánica no invasiva en la agudización de EPOC. Fisiopatología. Metodología I" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "V. Cabriada Nuño" 1 => "J. Camino" 2 => "M. Temprano" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:4 [ "titulo" => "Tratado de ventilación mecánica no invasiva. Práctica clínica y metodología" "paginaInicial" => "709" "paginaFinal" => "715" "serieFecha" => "2006" ] ] ] ] ] ] 66 => array:3 [ "identificador" => "bib67" "etiqueta" => "67." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Evolución comparativa con ventilación no invasiva de pacientes con EPOC, síndrome de hipoventilaciónobesidad e insuficiencia cardiaca congestiva ingresados en una unidad de monitorización respiratoria" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "A. Ortega González" 1 => "G. Peces-Barba Romero" 2 => "I. Fernández Ormaechea" 3 => "R. Chumbi Flores" 4 => "N. Cubero de Frutos" 5 => "N. González Mangado" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Bronconeumol" "fecha" => "2006" "volumen" => "42" "paginaInicial" => "423" "paginaFinal" => "429" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17040656" "web" => "Medline" ] ] ] ] ] ] ] ] 67 => array:3 [ "identificador" => "bib68" "etiqueta" => "68." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Ventilación mecánica domiciliaria en la enfermedad pulmonar obstructiva crónica" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "S. López Martín" 1 => "B. López-Muñíz Ballesteros" 2 => "J.M. Rodríguez González-Moro" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:4 [ "titulo" => "Insuficiencia respiratoria" "paginaInicial" => "291" "paginaFinal" => "300" "serieFecha" => "2006" ] ] ] ] ] ] 68 => array:3 [ "identificador" => "bib69" "etiqueta" => "69." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Insuficiencia cardiaca y ventilación no invasiva" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "A. Caníbal Berlanga" 1 => "D. Cabestero Alonso" 2 => "C. Martín Parra" 3 => "M.L. Rodríguez Blanco" 4 => "S Sáez Noguero" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:4 [ "titulo" => "Tratado de ventilación mecánica no invasiva. Práctica clínica y metodología" "paginaInicial" => "321" "paginaFinal" => "325" "serieFecha" => "2006" ] ] ] ] ] ] 69 => array:3 [ "identificador" => "bib70" "etiqueta" => "70." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Haemodynamic and endocrinological effects of noninvasive mechanical ventilation in respiratory failure" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "J.B. Thorens" 1 => "M. Ritz" 2 => "C. Reynard" 3 => "A. Righetti" 4 => "M. Vallotton" 5 => "H. Favre" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Eur Respir J" "fecha" => "1997" "volumen" => "10" "paginaInicial" => "2553" "paginaFinal" => "2559" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9426094" "web" => "Medline" ] ] ] ] ] ] ] ] 70 => array:3 [ "identificador" => "bib71" "etiqueta" => "71." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Ventilación mecánica no invasiva en el edema agudo de pulmón" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "J. Masip" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Rev Esp Cardiol" "fecha" => "2001" "volumen" => "9" "paginaInicial" => "1023" "paginaFinal" => "1028" ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15792129/0000004500000008/v1_201305150428/S1579212909729374/v1_201305150428/en/main.assets" "Apartado" => array:4 [ "identificador" => "14573" "tipo" => "SECCION" "es" => array:2 [ "titulo" => "Review article" "idiomaDefecto" => true ] "idiomaDefecto" => "es" ] "PDF" => "https://static.elsevier.es/multimedia/15792129/0000004500000008/v1_201305150428/S1579212909729374/v1_201305150428/en/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212909729374?idApp=UINPBA00003Z" ]
| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 7 | 4 | 11 |
| 2024 October | 40 | 17 | 57 |
| 2024 September | 39 | 16 | 55 |
| 2024 August | 77 | 44 | 121 |
| 2024 July | 39 | 26 | 65 |
| 2024 June | 37 | 40 | 77 |
| 2024 May | 72 | 50 | 122 |
| 2024 April | 33 | 25 | 58 |
| 2024 March | 49 | 15 | 64 |
| 2024 February | 20 | 15 | 35 |
| 2023 October | 0 | 1 | 1 |
| 2023 September | 1 | 4 | 5 |
| 2023 March | 0 | 1 | 1 |
| 2023 February | 20 | 19 | 39 |
| 2023 January | 18 | 24 | 42 |
| 2022 December | 25 | 26 | 51 |
| 2022 November | 23 | 25 | 48 |
| 2022 October | 31 | 39 | 70 |
| 2022 September | 17 | 25 | 42 |
| 2022 August | 25 | 43 | 68 |
| 2022 July | 20 | 36 | 56 |
| 2022 June | 17 | 27 | 44 |
| 2022 May | 25 | 34 | 59 |
| 2022 April | 15 | 23 | 38 |
| 2022 March | 18 | 38 | 56 |
| 2022 February | 32 | 25 | 57 |
| 2022 January | 20 | 45 | 65 |
| 2021 December | 25 | 49 | 74 |
| 2021 November | 28 | 59 | 87 |
| 2021 October | 44 | 56 | 100 |
| 2021 September | 49 | 68 | 117 |
| 2021 August | 23 | 40 | 63 |
| 2021 July | 22 | 32 | 54 |
| 2021 June | 29 | 35 | 64 |
| 2021 May | 19 | 35 | 54 |
| 2021 April | 25 | 64 | 89 |
| 2021 March | 16 | 18 | 34 |
| 2021 February | 15 | 20 | 35 |
| 2021 January | 11 | 16 | 27 |
| 2020 December | 10 | 17 | 27 |
| 2020 November | 12 | 22 | 34 |
| 2020 October | 17 | 14 | 31 |
| 2020 September | 7 | 6 | 13 |
| 2020 August | 18 | 18 | 36 |
| 2020 July | 13 | 14 | 27 |
| 2020 June | 8 | 8 | 16 |
| 2020 May | 17 | 20 | 37 |
| 2020 April | 16 | 16 | 32 |
| 2020 March | 18 | 18 | 36 |
| 2020 February | 25 | 38 | 63 |
| 2020 January | 21 | 34 | 55 |
| 2019 December | 18 | 24 | 42 |
| 2019 November | 10 | 24 | 34 |
| 2019 October | 5 | 14 | 19 |
| 2019 September | 8 | 17 | 25 |
| 2019 August | 16 | 11 | 27 |
| 2019 July | 7 | 19 | 26 |
| 2019 June | 8 | 9 | 17 |
| 2019 May | 14 | 14 | 28 |
| 2019 April | 11 | 15 | 26 |
| 2019 March | 17 | 26 | 43 |
| 2019 February | 7 | 11 | 18 |
| 2019 January | 2 | 28 | 30 |
| 2018 December | 10 | 42 | 52 |
| 2018 November | 22 | 14 | 36 |
| 2018 October | 15 | 14 | 29 |
| 2018 September | 13 | 10 | 23 |
| 2018 May | 7 | 0 | 7 |
| 2018 April | 7 | 2 | 9 |
| 2018 March | 4 | 5 | 9 |
| 2018 February | 7 | 5 | 12 |
| 2018 January | 7 | 9 | 16 |
| 2017 December | 4 | 11 | 15 |
| 2017 November | 3 | 2 | 5 |
| 2017 October | 7 | 7 | 14 |
| 2017 September | 4 | 6 | 10 |
| 2017 August | 6 | 13 | 19 |
| 2017 July | 16 | 10 | 26 |
| 2017 June | 11 | 11 | 22 |
| 2017 May | 4 | 8 | 12 |
| 2017 April | 4 | 5 | 9 |
| 2017 March | 5 | 26 | 31 |
| 2017 February | 4 | 5 | 9 |
| 2017 January | 2 | 4 | 6 |
| 2016 December | 8 | 6 | 14 |
| 2016 November | 11 | 10 | 21 |
| 2016 October | 10 | 18 | 28 |
| 2016 September | 8 | 12 | 20 |
| 2016 August | 5 | 3 | 8 |
| 2016 July | 5 | 5 | 10 |
| 2016 May | 1 | 0 | 1 |
| 2016 April | 1 | 0 | 1 |
| 2016 March | 8 | 0 | 8 |
| 2016 February | 6 | 0 | 6 |
| 2016 January | 6 | 0 | 6 |
| 2015 December | 4 | 0 | 4 |
| 2015 October | 157 | 14 | 171 |
| 2015 September | 166 | 18 | 184 |
| 2015 August | 127 | 11 | 138 |
| 2015 July | 226 | 18 | 244 |
| 2015 June | 149 | 14 | 163 |
| 2015 May | 172 | 12 | 184 |
| 2015 April | 164 | 19 | 183 |
| 2015 March | 170 | 9 | 179 |
| 2015 February | 169 | 9 | 178 |
| 2015 January | 106 | 7 | 113 |
| 2014 December | 94 | 13 | 107 |
| 2014 November | 134 | 13 | 147 |
| 2014 October | 165 | 18 | 183 |
| 2014 September | 141 | 15 | 156 |
| 2014 August | 145 | 16 | 161 |
| 2014 July | 168 | 16 | 184 |
| 2014 June | 167 | 7 | 174 |
| 2014 May | 161 | 21 | 182 |
| 2014 April | 144 | 6 | 150 |
| 2014 March | 130 | 22 | 152 |
| 2014 February | 115 | 16 | 131 |
| 2014 January | 97 | 7 | 104 |
| 2013 December | 84 | 8 | 92 |
| 2013 November | 91 | 12 | 103 |
| 2013 October | 88 | 12 | 100 |
| 2013 September | 103 | 25 | 128 |
| 2013 August | 103 | 6 | 109 |
| 2013 July | 91 | 14 | 105 |
| 2013 June | 59 | 12 | 71 |
| 2013 May | 59 | 6 | 65 |
| 2013 April | 31 | 5 | 36 |
| 2013 March | 8 | 5 | 13 |
Show all
