Recommendations of the Spanish Society of Pulmonology and Thoracic Surgery (Separ)
Guidelines on Asthma in Extreme Environmental Conditions
Guía del asma en condiciones ambientales extremas
a Servicios Médicos, FC Barcelona, Departamento de Fisiología del Deporte, Centro de Alto Rendimiento, Sant Cugat del Vallès, Barcelona, Spain
b Sección de Respiratorio, Hospital San Jorge, Departamento de Patología Médica, Facultad de Ciencias de la Salud y del Deporte, Campus de Huesca, Universidad de Zaragoza, Huesca, Spain
Read
7452
Timeswas read the article
2177
Total PDF
5275
Total HTML
Share statistics
array:23 [ "pii" => "S1579212909717884" "issn" => "15792129" "doi" => "10.1016/S1579-2129(09)71788-4" "estado" => "S300" "fechaPublicacion" => "2009-01-01" "aid" => "71788" "copyright" => "Sociedad Española de Neumología y Cirugía Torácica" "copyrightAnyo" => "2009" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Arch Bronconeumol. 2009;45:48-56" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 5285 "formatos" => array:3 [ "EPUB" => 112 "HTML" => 4314 "PDF" => 859 ] ] "itemSiguiente" => array:18 [ "pii" => "S1579212909717896" "issn" => "15792129" "doi" => "10.1016/S1579-2129(09)71789-6" "estado" => "S300" "fechaPublicacion" => "2009-01-01" "aid" => "71789" "copyright" => "Sociedad Española de Neumología y Cirugía Torácica" "documento" => "article" "crossmark" => 0 "subdocumento" => "sco" "cita" => "Arch Bronconeumol. 2009;45:57-9" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 4300 "formatos" => array:3 [ "EPUB" => 91 "HTML" => 3323 "PDF" => 886 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case Report</span>" "titulo" => "Diffuse Interstitial Lung Disease Related to Peribronchiolar Metaplasia" "tienePdf" => "en" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "57" "paginaFinal" => "59" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Enfermedad pulmonar intersticial difusa por metaplasia peribronquiolar" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Esteban Cano-Jiménez, María Molina-Molina, José Ramírez, Marcelo Sánchez, Joan Lluís Aliag, Antoni Xaubet" "autores" => array:6 [ 0 => array:2 [ "nombre" => "Esteban" "apellidos" => "Cano-Jiménez" ] 1 => array:2 [ "nombre" => "María" "apellidos" => "Molina-Molina" ] 2 => array:2 [ "nombre" => "José" "apellidos" => "Ramírez" ] 3 => array:2 [ "nombre" => "Marcelo" "apellidos" => "Sánchez" ] 4 => array:2 [ "nombre" => "Joan Lluís" "apellidos" => "Aliag" ] 5 => array:2 [ "nombre" => "Antoni" "apellidos" => "Xaubet" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212909717896?idApp=UINPBA00003Z" "url" => "/15792129/0000004500000001/v1_201305150402/S1579212909717896/v1_201305150402/en/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S1579212909717872" "issn" => "15792129" "doi" => "10.1016/S1579-2129(09)71787-2" "estado" => "S300" "fechaPublicacion" => "2009-01-01" "aid" => "71787" "copyright" => "Sociedad Española de Neumología y Cirugía Torácica" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Arch Bronconeumol. 2009;45:41-7" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 3246 "formatos" => array:3 [ "EPUB" => 108 "HTML" => 2241 "PDF" => 897 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Special Article</span>" "titulo" => "The EPI-SCAN Survey to Assess the Prevalence of Chronic Obstructive Pulmonary Disease in Spanish 40-to-80-Year-Olds: Protocol Summary" "tienePdf" => "en" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "41" "paginaFinal" => "47" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Estudio EPI-SCAN: resumen del protocolo de un estudio para estimar la prevalencia de EPOC en personas de 40 a 80 años en España" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Julio Ancochea, Carlos Badiola, Enric Duran-Tauleria, Francisco García Río, Marc Miravitlles, Luis Muñoz, Víctor Sobradillo, Juan B. Soriano" "autores" => array:8 [ 0 => array:2 [ "nombre" => "Julio" "apellidos" => "Ancochea" ] 1 => array:2 [ "nombre" => "Carlos" "apellidos" => "Badiola" ] 2 => array:2 [ "nombre" => "Enric" "apellidos" => "Duran-Tauleria" ] 3 => array:2 [ "nombre" => "Francisco García" "apellidos" => "Río" ] 4 => array:2 [ "nombre" => "Marc" "apellidos" => "Miravitlles" ] 5 => array:2 [ "nombre" => "Luis" "apellidos" => "Muñoz" ] 6 => array:2 [ "nombre" => "Víctor" "apellidos" => "Sobradillo" ] 7 => array:2 [ "nombre" => "Juan B." "apellidos" => "Soriano" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212909717872?idApp=UINPBA00003Z" "url" => "/15792129/0000004500000001/v1_201305150402/S1579212909717872/v1_201305150402/en/main.assets" ] "en" => array:15 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Recommendations of the Spanish Society of Pulmonology and Thoracic Surgery (Separ)</span>" "titulo" => "Guidelines on Asthma in Extreme Environmental Conditions" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "48" "paginaFinal" => "56" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Franchek Drobnic, Luis Borderías Clau" "autores" => array:2 [ 0 => array:4 [ "nombre" => "Franchek" "apellidos" => "Drobnic" "email" => array:1 [ 0 => "drobnic@car.edu" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor1" ] ] ] 1 => array:3 [ "nombre" => "Luis Borderías" "apellidos" => "Clau" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicios Médicos, FC Barcelona, Departamento de Fisiología del Deporte, Centro de Alto Rendimiento, Sant Cugat del Vallès, Barcelona, Spain" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:3 [ "entidad" => "Sección de Respiratorio, Hospital San Jorge, Departamento de Patología Médica, Facultad de Ciencias de la Salud y del Deporte, Campus de Huesca, Universidad de Zaragoza, Huesca, Spain" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Guía del asma en condiciones ambientales extremas" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2008-08-27" "fechaAceptado" => "2008-09-02" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec155450" "palabras" => array:6 [ 0 => "Asthma" 1 => "Extreme conditions" 2 => "Mountain" 3 => "Winter sports" 4 => "Desert" 5 => "Underwater activities" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec155449" "palabras" => array:6 [ 0 => "Asma" 1 => "Condiciones extremas" 2 => "Montaña" 3 => "Deportes de invierno" 4 => "Desierto" 5 => "Actividad subacuática" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">Asthma is a highly prevalent chronic disease which, if not properly controlled, can limit the patient's activities and lifestyle. In recent decades, owing to the diffusion of educational materials, the application of clinical guidelines and, most importantly, the availability of effective pharmacological treatment, most patients with asthma are now able to lead normal lives.</p><p class="elsevierStyleSimplePara elsevierViewall">Significant social changes have also taken place during the same period, including more widespread pursuit of sporting activities and tourism. As a result of these changes, individuals with asthma can now participate in certain activities that were inconceivable for these patients only a few years ago, including winter sports, underwater activities, air flight, and travel to remote places with unusual environmental conditions (deserts, high mountain environments, and tropical regions). In spite of the publication of several studies on this subject, our understanding of the effects of these situations on patients with asthma is still limited. The Spanish Society of Pulmonology and Thoracic Surgery (SEPAR) has decided to publish these recommendations based on the available evidence and expert opinion in order to provide information on this topic to both doctors and patients and to avert potentially dangerous situations that could endanger the lives of these patients.</p>" ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">El asma es una enfermedad crónica de alta prevalencia que puede condicionar la vida del paciente si no se logra un control adecuado. En las últimas décadas, gracias a la difusión de los programas de educación, la aplicación de las guías clínicas y, fundamentalmente, la aparición de fármacos efectivos, la mayoría de los pacientes logra llevar un régimen de vida normal.</p><p class="elsevierStyleSimplePara elsevierViewall">Por otra parte, en estos mismos años se han producido importantes cambios sociales, como la generalización de la práctica deportiva y del turismo. Ambas situaciones permiten al paciente asmático realizar determinadas actividades que hace sólo unos años parecían impensables, como los deportes de invierno, las actividades subacuáticas y los viajes a lugares remotos con condiciones ambientales inusuales (desierto, alta montaña, trópicos o vuelos en avión). A pesar de la publicación de algunos estudios, el conocimiento de las consecuencias de estas situaciones en el paciente con asma es limitado. La Sociedad Española de Neumología y Cirugía Torácica (SEPAR) ha decidido publicar estas Recomendaciones, basadas en la información disponible y/o en consejos de expertos, en un intento de facilitar la información a medicos y pacientes, con el fin de evitar situaciones peligrosas que puedan poner en peligro la vida de los pacientes.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:54 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Exercise-induced asthma, respiratory and allergic disorders in elite athletes: epidemiology, mechanisms and diagnosis: part I of the report from the Joint Task Force of the European Respiratory Society (ERS) and the European Academy of Allergy and Clinical Immunology (EAACI) in cooperation with GA<span class="elsevierStyleSup">2</span>LEN" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "K.H. Carlsen" 1 => "S.D. Anderson" 2 => "L. Bjermer" 3 => "S. Bonini" 4 => "V. Brusasco" 5 => "W. Canonica" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1398-9995.2008.01662.x" "Revista" => array:6 [ "tituloSerie" => "Allergy" "fecha" => "2008" "volumen" => "63" "paginaInicial" => "387" "paginaFinal" => "403" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18315727" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Asthma in athletes. Exercise-induced bronchoconstriction in figure skaters" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "W. Corrao" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "1996" "volumen" => "109" "paginaInicial" => "298" "paginaFinal" => "299" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8620691" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib3" "etiqueta" => "3." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Prevalence and characteristics of late asthmatic responses to exercise" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "L.P. Boulet" 1 => "C. Legris" 2 => "M. Turcotte" 3 => "J. Hebert" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Allergy Clin Immunol" "fecha" => "1987" "volumen" => "80" "paginaInicial" => "665" "paginaFinal" => "672" ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib4" "etiqueta" => "4." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Exercise-induced asthma: clinical, physiological, and therapeutic implications" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "S. Godfrey" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Allergy Clin Immunol" "fecha" => "1975" "volumen" => "56" "paginaInicial" => "1" "paginaFinal" => "17" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/805807" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib5" "etiqueta" => "5." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Duration of protective effect of terbutaline sulphate and cromolyn sodium a combination on exercise-induced asthma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "M. Wooley" 1 => "S.D. Anderson" 2 => "B.M. Quigley" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "1990" "volumen" => "97" "paginaInicial" => "39" "paginaFinal" => "45" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2104792" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib6" "etiqueta" => "6." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Montelukast a leukotriene-receptor antagonist, for the treatment of mild asthma and exercise-induced bronchoconstriction" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "J.A. Leff" 1 => "W.W. Busse" 2 => "D. Pearlman" 3 => "E.A. Bronsky" 4 => "J. Kemp" 5 => "L. Hendeles" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1056/NEJM199807163390302" "Revista" => array:6 [ "tituloSerie" => "N Engl J Med" "fecha" => "1998" "volumen" => "339" "paginaInicial" => "147" "paginaFinal" => "152" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9664090" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib7" "etiqueta" => "7." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Exercise-induced asthma. Stimulus, mechanism and management" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "S.D. Anderson" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:4 [ "titulo" => "Asthma: basic mechanisms and clinical management" "paginaInicial" => "503" "paginaFinal" => "522" "serieFecha" => "1988" ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib8" "etiqueta" => "8." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The effect of an inhaled corticosteroid (budesonide) on exercise-induced asthma in children" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "H.J. Waalkens" 1 => "E.E. Van Essen-Zanduliel" 2 => "J. Gerrilsen" 3 => "E.J. Duiverman" 4 => "K. Knol" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Eur Respir J" "fecha" => "1993" "volumen" => "6" "paginaInicial" => "652" "paginaFinal" => "656" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8519374" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib9" "etiqueta" => "9." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Heat and water loss from the airways and exercise-induced asthma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "W.Y. Chen" 1 => "D.J. Horton" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Respiration" "fecha" => "1977" "volumen" => "34" "paginaInicial" => "305" "paginaFinal" => "313" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/918355" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib10" "etiqueta" => "10." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A reinterpretation of the effect of temperature and water content of the inspired air in exercise-induced asthma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "A. Hahn" 1 => "S.D. Anderson" 2 => "A. Morton" 3 => "J.L. Black" 4 => "K.D. Fitch" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/arrd.1984.130.4.575" "Revista" => array:6 [ "tituloSerie" => "Am Rev Respir Dis" "fecha" => "1984" "volumen" => "130" "paginaInicial" => "575" "paginaFinal" => "579" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6486555" "web" => "Medline" ] ] ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib11" "etiqueta" => "11." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The bronchoconstrictor effect of strenuous exercise at low temperatures in normal athletes" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "D.W. Paul" 1 => "J.M. Bogaard" 2 => "W.C. Hop" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1055/s-2007-1021205" "Revista" => array:6 [ "tituloSerie" => "Int J Sports Med" "fecha" => "1993" "volumen" => "14" "paginaInicial" => "433" "paginaFinal" => "436" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8300267" "web" => "Medline" ] ] ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib12" "etiqueta" => "12." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Postexertional airway rewarming and thermally induced asthma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "E.R. McFadden" 1 => "K.A. Lenner" 2 => "K.P. Strohl" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1172/JCI112549" "Revista" => array:6 [ "tituloSerie" => "J Clin Invest" "fecha" => "1986" "volumen" => "78" "paginaInicial" => "18" "paginaFinal" => "25" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3722374" "web" => "Medline" ] ] ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib13" "etiqueta" => "13." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The role of the environment and climate in relation to outdoor and indoor sports" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "F. Drobnic" 1 => "T. Haahtela" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Respir Monogr" "fecha" => "2005" "volumen" => "33" "paginaInicial" => "35" "paginaFinal" => "47" ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib14" "etiqueta" => "14." "referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "World Antidoping Agency. Available from: <a class="elsevierStyleInterRef" href="http://www.wada-ama.org/">http://www.wada-ama.org</a>" ] ] ] 14 => array:3 [ "identificador" => "bib15" "etiqueta" => "15." "referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "Consejo Superior de Deportes. Available from: <a class="elsevierStyleInterRef" href="http://www.csd.mec.es/">http://www.csd.mec.es</a>" ] ] ] 15 => array:3 [ "identificador" => "bib16" "etiqueta" => "16." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Nasal mucociliary transport is impaired at altitude" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "P.W. Barry" 1 => "N.P. Mason" 2 => "C. O’Callaghan" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Eur Respir J" "fecha" => "1997" "volumen" => "10" "paginaInicial" => "35" "paginaFinal" => "37" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9032488" "web" => "Medline" ] ] ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bib17" "etiqueta" => "17." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "La consultation de medicine de montagne" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "J.P. Richalet" 1 => "J.P. Herry" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:5 [ "titulo" => "Mèdecine de l’alpinisme et des sports de montagne" "paginaInicial" => "235" "paginaFinal" => "255" "edicion" => "3<span class="elsevierStyleSup">rd</span> ed." "serieFecha" => "2003" ] ] ] ] ] ] 17 => array:3 [ "identificador" => "bib18" "etiqueta" => "18." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lack of effects of moderate-high altitude upon lung function in healthy middle-age volunteers" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "P. Casan" 1 => "B. Togores" 2 => "J. Giner" 3 => "I. Nerín" 4 => "F. Drobnic" 5 => "L. Borderías" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Respir Med" "fecha" => "1999" "volumen" => "93" "paginaInicial" => "739" "paginaFinal" => "743" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10581664" "web" => "Medline" ] ] ] ] ] ] ] ] 18 => array:3 [ "identificador" => "bib19" "etiqueta" => "19." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Asthma bronchiale und klima" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "S. van Leeuven" 1 => "H. Varekamp" 2 => "Z. Bien" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Klin Wochenschr" "fecha" => "1924" "volumen" => "3" "paginaInicial" => "250" ] ] ] ] ] ] 19 => array:3 [ "identificador" => "bib20" "etiqueta" => "20." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "High altitude and house dust mites" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "F. Spieksma" 1 => "P. Zuidema" 2 => "H.J. Leuden" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Br Med J" "fecha" => "1971" "volumen" => "1" "paginaInicial" => "82" "paginaFinal" => "84" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/761002" "web" => "Medline" ] ] ] ] ] ] ] ] 20 => array:3 [ "identificador" => "bib21" "etiqueta" => "21." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pulmonary function and bronchial hyperreactivity in asthmatic children with house dust mite allergy during prolonged stay in the Italian Alps (Misurina 1756 m)" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "A.L. Boner" 1 => "E. Niero" 2 => "I. Antolini" 3 => "A. Valletta" 4 => "D. Gaburro" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Ann Allergy" "fecha" => "1985" "volumen" => "54" "paginaInicial" => "42" "paginaFinal" => "45" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3966688" "web" => "Medline" ] ] ] ] ] ] ] ] 21 => array:3 [ "identificador" => "bib22" "etiqueta" => "22." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Donnés objectives cliniques et inmunologiques observées au cours d’une cure d’altitude a Briançon chez es enfants asthmatiques allergiques a la poussière de maison et <span class="elsevierStyleItalic">Dermatophagoides</span>" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "D. Vervloet" 1 => "P. Bongrand" 2 => "A. Arnaud" 3 => "C. Boutin" 4 => "J. Charpin" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Rev Fr Mal Resp" "fecha" => "1979" "volumen" => "7" "paginaInicial" => "19" "paginaFinal" => "27" ] ] ] ] ] ] 22 => array:3 [ "identificador" => "bib23" "etiqueta" => "23." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Benefits of high altitude allergen avoidance in atopic adolescents with moderate to severe asthma, over and above treatment with high dose inhaled steroids" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "D.C. Grootendorst" 1 => "S.E. Dahlen" 2 => "J.W. van den Bos" 3 => "E.J. Duiverman" 4 => "M. Veselic-Charvat" 5 => "E.J. Vrijlandt" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Clin Exper Allergy" "fecha" => "2001" "volumen" => "31" "paginaInicial" => "400" "paginaFinal" => "408" ] ] ] ] ] ] 23 => array:3 [ "identificador" => "bib24" "etiqueta" => "24." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Highaltitude climate therapy reduces local airway inflammation and modulates lymphocyte activation" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "C. Karagiannidis" 1 => "B. Hense" 2 => "P. Rueckert" 3 => "Y. Mantel" 4 => "B. Ichters" 5 => "K. Blaser" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Scand J Inmunol" "fecha" => "2006" "volumen" => "63" "paginaInicial" => "304" "paginaFinal" => "310" ] ] ] ] ] ] 24 => array:3 [ "identificador" => "bib25" "etiqueta" => "25." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effect of acetazolamide on overnight oxygenation and acute mountain sickness in patients with asthma" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "M. Mirrakhimov" 1 => "N. Brimkulov" 2 => "J. Cieslicki" 3 => "M. Tobias" 4 => "Z. Kudiaverdiev" 5 => "I. Moldotashev" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Eur Respir J" "fecha" => "1993" "volumen" => "6" "paginaInicial" => "536" "paginaFinal" => "540" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8491304" "web" => "Medline" ] ] ] ] ] ] ] ] 25 => array:3 [ "identificador" => "bib26" "etiqueta" => "26." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Medical conditions at altitude" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "M.P. Ward" 1 => "J.S. Milledge" 2 => "J.B. West" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:5 [ "titulo" => "High altitude medicine and physiology" "paginaInicial" => "322" "paginaFinal" => "328" "edicion" => "3<span class="elsevierStyleSup">rd</span> ed." "serieFecha" => "2000" ] ] ] ] ] ] 26 => array:3 [ "identificador" => "bib27" "etiqueta" => "27." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pathologie liée à l’hypoxie d’altitude" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "J.P. Richalet" 1 => "J.P. Herry" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:5 [ "titulo" => "Mèdecine de l’alpinisme et des sports de montagne" "paginaInicial" => "139" "paginaFinal" => "162" "edicion" => "3<span class="elsevierStyleSup">rd</span> ed." "serieFecha" => "2003" ] ] ] ] ] ] 27 => array:3 [ "identificador" => "bib28" "etiqueta" => "28." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cough frequency and cough receptor sensitivity to citric acid challenge during a simulated ascent to extreme altitude" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "N.P. Mason" 1 => "P.W. Barry" 2 => "G. Despiau" 3 => "D. Gardette" 4 => "J.P. Richalet" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Eur Respir J" "fecha" => "1999" "volumen" => "13" "paginaInicial" => "508" "paginaFinal" => "513" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10232417" "web" => "Medline" ] ] ] ] ] ] ] ] 28 => array:3 [ "identificador" => "bib29" "etiqueta" => "29." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Short term exposure to high altitude causes coagulation activation and inhibits fibrinolysis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "P.M. Manucci" 1 => "A. Gringeri" 2 => "F. Peyvandi" 3 => "T. di Paolantonio" 4 => "G. Mariano" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Tromb Haemost" "fecha" => "2002" "volumen" => "87" "paginaInicial" => "342" "paginaFinal" => "343" ] ] ] ] ] ] 29 => array:3 [ "identificador" => "bib30" "etiqueta" => "30." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Tromboembolismo pulmonar en alta montaña" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "I. Soteras" 1 => "M. Bernabé" 2 => "E. Capella" 3 => "J. Molinos" 4 => "J.M. Fácil" 5 => "M. Montañés" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:4 [ "titulo" => "Progresos en medicina de montaña" "paginaInicial" => "413" "paginaFinal" => "414" "serieFecha" => "2004" ] ] ] ] ] ] 30 => array:3 [ "identificador" => "bib31" "etiqueta" => "31." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "El flujo espiratorio máximo en expediciones al Himalaya" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "L. Borderías" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Arch Bronconeumol" "fecha" => "1999" "volumen" => "35" "numero" => "Supl 3" "paginaInicial" => "49" "paginaFinal" => "54" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10410225" "web" => "Medline" ] ] ] ] ] ] ] ] 31 => array:3 [ "identificador" => "bib32" "etiqueta" => "32." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effects of extreme temperatures on drug delivery of albuterol sulfate hydrofluoroalkane inhalation aerosols" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "W.L. Hoye" 1 => "E.M. Mogalian" 2 => "P.B. Myrdal" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.2146/ajhp050067" "Revista" => array:7 [ "tituloSerie" => "Am J Health Syst Pharm" "fecha" => "2005" "volumen" => "62" "paginaInicial" => "2271" "paginaFinal" => "2277" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16239418" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0140673604165914" "estado" => "S300" "issn" => "01406736" ] ] ] ] ] ] ] 32 => array:3 [ "identificador" => "bib33" "etiqueta" => "33." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Salmeterol for the prevention of high altitude pulmonary edema" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "C. Sartori" 1 => "Y. Allemann" 2 => "H. Duplain" 3 => "M. Lepori" 4 => "M. Egli" 5 => "E. Lipp" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1056/NEJMoa013183" "Revista" => array:6 [ "tituloSerie" => "N Engl J Med" "fecha" => "2002" "volumen" => "346" "paginaInicial" => "1631" "paginaFinal" => "1636" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12023995" "web" => "Medline" ] ] ] ] ] ] ] ] 33 => array:3 [ "identificador" => "bib34" "etiqueta" => "34." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effect of zolpidem on sleep and ventilatory patterns at simulated altitude of 4000 meters" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "M. Beaumont" 1 => "F. Goldenberg" 2 => "D. Lejeune" 3 => "H. Marotte" 4 => "A. Harf" 5 => "F. Lofaso" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/ajrccm.153.6.8665047" "Revista" => array:6 [ "tituloSerie" => "Am J Respir Crit Care Med" "fecha" => "1996" "volumen" => "153" "paginaInicial" => "1864" "paginaFinal" => "1869" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8665047" "web" => "Medline" ] ] ] ] ] ] ] ] 34 => array:3 [ "identificador" => "bib35" "etiqueta" => "35." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Inhalation of cold air increases the number of inflammatory cells in the lungs in healthy subjects" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "K. Larsson" 1 => "G. Tornling" 2 => "D. Gavhed" 3 => "C. Müller-Suur" 4 => "L. Palmberg" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Eur Respir J" "fecha" => "1998" "volumen" => "12" "paginaInicial" => "825" "paginaFinal" => "830" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9817153" "web" => "Medline" ] ] ] ] ] ] ] ] 35 => array:3 [ "identificador" => "bib36" "etiqueta" => "36." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Evidence of airway inflammation and remodeling in ski athletes with and without bronchial hyperresponsiveness to methacholine" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "E.M. Karjalainen" 1 => "A. Latineen" 2 => "M. Sue Chu" 3 => "A. Altraja" 4 => "L. Bjermer" 5 => "L.A. Laitinen" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/ajrccm.161.6.9907025" "Revista" => array:6 [ "tituloSerie" => "Am J Respir Crit Care Med" "fecha" => "2000" "volumen" => "161" "paginaInicial" => "2086" "paginaFinal" => "2091" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10852791" "web" => "Medline" ] ] ] ] ] ] ] ] 36 => array:3 [ "identificador" => "bib37" "etiqueta" => "37." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Bronchial hyperresponsiveness in athletes: mechanisms for development" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "L. Bjermer" 1 => "S.D. Anderson" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Resp Monograph" "fecha" => "2005" "volumen" => "33" "paginaInicial" => "19" "paginaFinal" => "34" ] ] ] ] ] ] 37 => array:3 [ "identificador" => "bib38" "etiqueta" => "38." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Asthma in children exposed to nitrogen dioxide in ice arenas" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "P. Thunqvist" 1 => "G. Lilja" 2 => "M. Wickman" 3 => "G. Pershagen" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Eur Respir J" "fecha" => "2002" "volumen" => "20" "paginaInicial" => "646" "paginaFinal" => "650" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12358342" "web" => "Medline" ] ] ] ] ] ] ] ] 38 => array:3 [ "identificador" => "bib39" "etiqueta" => "39." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pulmonary responses of asthmatic and normal subjects to different temperature and humidity conditions in an environmental chamber" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "W.L. Eschenbacher" 1 => "T.B. Moore" 2 => "T.J. Lorenzen" 3 => "J.G. Weg" 4 => "K.B. Gross" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Lung" "fecha" => "1992" "volumen" => "170" "paginaInicial" => "51" "paginaFinal" => "62" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1732684" "web" => "Medline" ] ] ] ] ] ] ] ] 39 => array:3 [ "identificador" => "bib40" "etiqueta" => "40." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Influence of climate factors on emergency visits for childhood asthma attack" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "M. Hashimoto" 1 => "T. Fukuda" 2 => "T. Shimizu" 3 => "S. Watanabe" 4 => "S. Watanuki" 5 => "Y. Eto" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1442-200X.2004.01835.x" "Revista" => array:6 [ "tituloSerie" => "Pediatr Int" "fecha" => "2004" "volumen" => "46" "paginaInicial" => "48" "paginaFinal" => "52" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15043664" "web" => "Medline" ] ] ] ] ] ] ] ] 40 => array:3 [ "identificador" => "bib41" "etiqueta" => "41." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Mild dehydration: a risk factor of broncho-pulmonary disorders?" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "H. Kalhoff" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Eur J Clin Nutr" "fecha" => "2003" "volumen" => "57" "numero" => "Suppl 2" "paginaInicial" => "381" "paginaFinal" => "387" ] ] ] ] ] ] 41 => array:3 [ "identificador" => "bib42" "etiqueta" => "42." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effects of Asian dust storm events on daily admissions for asthma in Taipei, Taiwan" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "C.Y. Yang" 1 => "S.S. Tsai" 2 => "C.C. Chang" 3 => "S.C. Ho" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1080/08958370500241254" "Revista" => array:6 [ "tituloSerie" => "Inhal Toxicol" "fecha" => "2005" "volumen" => "17" "paginaInicial" => "817" "paginaFinal" => "821" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16282159" "web" => "Medline" ] ] ] ] ] ] ] ] 42 => array:3 [ "identificador" => "bib43" "etiqueta" => "43." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Exacerbation of asthma after pyridostigmine during Operation Desert Storm" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "S.F. Gouge" 1 => "D.J. Daniels" 2 => "C.E. Smith" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Mil Med" "fecha" => "1994" "volumen" => "159" "paginaInicial" => "108" "paginaFinal" => "111" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8202234" "web" => "Medline" ] ] ] ] ] ] ] ] 43 => array:3 [ "identificador" => "bib44" "etiqueta" => "44." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Particulate air pollution from bushfires: human exposure and possible health effects" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "S. Karthikeyan" 1 => "R. Balasubramanian" 2 => "K. Iouri" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Toxicol Environ Health" "fecha" => "2006" "volumen" => "69" "paginaInicial" => "1895" "paginaFinal" => "1908" ] ] ] ] ] ] 44 => array:3 [ "identificador" => "bib45" "etiqueta" => "45." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Adaptación al aire enrarecido de las simas y cuevas. Estudio de laboratorio" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "I. Yzaguirre" 1 => "V. Escoda" 2 => "V. Bosch" 3 => "J.A. Gutiérrez" 4 => "D. Dulanto" 5 => "R. Segura" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Apunts Medicina de l’Esport" "fecha" => "2008" "volumen" => "43" "paginaInicial" => "135" "paginaFinal" => "141" ] ] ] ] ] ] 45 => array:3 [ "identificador" => "bib46" "etiqueta" => "46." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Acute respiratory effects of particulate air pollution" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "D.W. Dockery" 1 => "C.A. Pope III" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1146/annurev.pu.15.050194.000543" "Revista" => array:6 [ "tituloSerie" => "Annu Rev Public Health" "fecha" => "1994" "volumen" => "15" "paginaInicial" => "107" "paginaFinal" => "132" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8054077" "web" => "Medline" ] ] ] ] ] ] ] ] 46 => array:3 [ "identificador" => "bib47" "etiqueta" => "47." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Asthma in exercising children exposed to ozone: a cohort study" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "R. McConnell" 1 => "K. Berhane" 2 => "F. Gilliland" 3 => "S.J. London" 4 => "T. Islam" 5 => "W.J. Gauderman" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/S0140-6736(02)07597-9" "Revista" => array:6 [ "tituloSerie" => "Lancet" "fecha" => "2002" "volumen" => "359" "paginaInicial" => "386" "paginaFinal" => "391" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11844508" "web" => "Medline" ] ] ] ] ] ] ] ] 47 => array:3 [ "identificador" => "bib48" "etiqueta" => "48." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Short term association between air pollution and emergency room visits for asthma in Barcelona" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "J. Castellsague" 1 => "J. Sunyer" 2 => "M. Saez" 3 => "J.M. Antó" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Thorax" "fecha" => "1995" "volumen" => "50" "paginaInicial" => "1051" "paginaFinal" => "1056" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7491552" "web" => "Medline" ] ] ] ] ] ] ] ] 48 => array:3 [ "identificador" => "bib49" "etiqueta" => "49." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Asthma and diving" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "C. Edmonds" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "SPUMPS Journal" "fecha" => "1991" "volumen" => "21" "paginaInicial" => "70" "paginaFinal" => "74" ] ] ] ] ] ] 49 => array:3 [ "identificador" => "bib50" "etiqueta" => "50." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Risk-assessment of asthma for decompression illness" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "K.E. Corson" 1 => "J.A. Dovenbarger" 2 => "R.E. Moon" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Undersea Biomed Res" "fecha" => "1991" "volumen" => "18" "numero" => "Suppl:16" ] ] ] ] ] ] 50 => array:3 [ "identificador" => "bib51" "etiqueta" => "51." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Diving practices of scuba divers with asthma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "P.J.S. Farrell" 1 => "P. Glanwill" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "BMJ" "fecha" => "1990" "volumen" => "300" "paginaInicial" => "166" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2105799" "web" => "Medline" ] ] ] ] ] ] ] ] 51 => array:3 [ "identificador" => "bib52" "etiqueta" => "52." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Scuba death due to asthmatic bronchitis, air embolism, and drowning" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "J.V. Marraccini" 1 => "P.L. Friedman" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Forensic Pathology" "fecha" => "1986" "volumen" => "28" "paginaInicial" => "1" "paginaFinal" => "4" ] ] ] ] ] ] 52 => array:3 [ "identificador" => "bib53" "etiqueta" => "53." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Patología respiratoria y vuelos en avión" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "F. García" 1 => "L. Borderías" 2 => "C. Casanova" 3 => "B.R. Celli" 4 => "J. Escarrabill" 5 => "N. González" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Bronconeumol" "fecha" => "2007" "volumen" => "43" "paginaInicial" => "101" "paginaFinal" => "125" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17288899" "web" => "Medline" ] ] ] ] ] ] ] ] 53 => array:3 [ "identificador" => "bib54" "etiqueta" => "54." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Development of the asthma control test: a survey for assessing asthma control" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "R.A. Nathan" 1 => "C.A. Sorkness" 2 => "M. Kosinski" 3 => "M. Schatz" 4 => "J.T. Li" 5 => "P. Marcus" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.jaci.2003.09.008" "Revista" => array:6 [ "tituloSerie" => "J Allergy Clin Immunol" "fecha" => "2004" "volumen" => "113" "paginaInicial" => "59" "paginaFinal" => "65" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14713908" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15792129/0000004500000001/v1_201305150402/S1579212909717884/v1_201305150402/en/main.assets" "Apartado" => array:4 [ "identificador" => "14574" "tipo" => "SECCION" "es" => array:2 [ "titulo" => "Recommendations of the Spanish Society of Pulmonology and Thoracic Surgery (SEPAR)" "idiomaDefecto" => true ] "idiomaDefecto" => "es" ] "PDF" => "https://static.elsevier.es/multimedia/15792129/0000004500000001/v1_201305150402/S1579212909717884/v1_201305150402/en/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212909717884?idApp=UINPBA00003Z" ]
| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 1 | 5 | 6 |
| 2024 October | 30 | 16 | 46 |
| 2024 September | 26 | 17 | 43 |
| 2024 August | 53 | 33 | 86 |
| 2024 July | 24 | 19 | 43 |
| 2024 June | 34 | 27 | 61 |
| 2024 May | 43 | 38 | 81 |
| 2024 April | 17 | 16 | 33 |
| 2024 March | 19 | 15 | 34 |
| 2024 February | 16 | 21 | 37 |
| 2023 March | 7 | 3 | 10 |
| 2023 February | 24 | 17 | 41 |
| 2023 January | 18 | 32 | 50 |
| 2022 December | 22 | 22 | 44 |
| 2022 November | 22 | 21 | 43 |
| 2022 October | 24 | 38 | 62 |
| 2022 September | 18 | 25 | 43 |
| 2022 August | 22 | 38 | 60 |
| 2022 July | 20 | 41 | 61 |
| 2022 June | 19 | 34 | 53 |
| 2022 May | 19 | 23 | 42 |
| 2022 April | 19 | 26 | 45 |
| 2022 March | 20 | 38 | 58 |
| 2022 February | 17 | 30 | 47 |
| 2022 January | 16 | 34 | 50 |
| 2021 December | 19 | 46 | 65 |
| 2021 November | 24 | 48 | 72 |
| 2021 October | 19 | 55 | 74 |
| 2021 September | 19 | 68 | 87 |
| 2021 August | 18 | 35 | 53 |
| 2021 July | 11 | 36 | 47 |
| 2021 June | 18 | 28 | 46 |
| 2021 May | 16 | 25 | 41 |
| 2021 April | 39 | 62 | 101 |
| 2021 March | 33 | 28 | 61 |
| 2021 February | 15 | 22 | 37 |
| 2021 January | 19 | 16 | 35 |
| 2020 December | 11 | 24 | 35 |
| 2020 November | 14 | 27 | 41 |
| 2020 October | 13 | 19 | 32 |
| 2020 September | 12 | 21 | 33 |
| 2020 August | 12 | 26 | 38 |
| 2020 July | 19 | 26 | 45 |
| 2020 June | 8 | 10 | 18 |
| 2020 May | 13 | 26 | 39 |
| 2020 April | 23 | 22 | 45 |
| 2020 March | 24 | 10 | 34 |
| 2020 February | 31 | 24 | 55 |
| 2020 January | 28 | 21 | 49 |
| 2019 December | 8 | 14 | 22 |
| 2019 November | 15 | 17 | 32 |
| 2019 October | 14 | 9 | 23 |
| 2019 September | 11 | 18 | 29 |
| 2019 August | 12 | 17 | 29 |
| 2019 July | 23 | 17 | 40 |
| 2019 June | 7 | 17 | 24 |
| 2019 May | 14 | 12 | 26 |
| 2019 April | 21 | 19 | 40 |
| 2019 March | 15 | 16 | 31 |
| 2019 February | 12 | 12 | 24 |
| 2019 January | 11 | 5 | 16 |
| 2018 December | 13 | 11 | 24 |
| 2018 November | 19 | 15 | 34 |
| 2018 October | 25 | 12 | 37 |
| 2018 September | 11 | 11 | 22 |
| 2018 May | 5 | 0 | 5 |
| 2018 April | 7 | 12 | 19 |
| 2018 March | 6 | 10 | 16 |
| 2018 February | 13 | 14 | 27 |
| 2018 January | 9 | 13 | 22 |
| 2017 December | 11 | 3 | 14 |
| 2017 November | 6 | 6 | 12 |
| 2017 October | 10 | 11 | 21 |
| 2017 September | 7 | 5 | 12 |
| 2017 August | 13 | 14 | 27 |
| 2017 July | 13 | 7 | 20 |
| 2017 June | 19 | 22 | 41 |
| 2017 May | 10 | 14 | 24 |
| 2017 April | 10 | 11 | 21 |
| 2017 March | 12 | 14 | 26 |
| 2017 February | 6 | 5 | 11 |
| 2017 January | 3 | 7 | 10 |
| 2016 December | 9 | 8 | 17 |
| 2016 November | 10 | 12 | 22 |
| 2016 October | 15 | 20 | 35 |
| 2016 September | 11 | 7 | 18 |
| 2016 August | 12 | 7 | 19 |
| 2016 July | 8 | 6 | 14 |
| 2016 March | 1 | 0 | 1 |
| 2016 February | 1 | 0 | 1 |
| 2015 December | 3 | 0 | 3 |
| 2015 October | 210 | 9 | 219 |
| 2015 September | 195 | 10 | 205 |
| 2015 August | 155 | 8 | 163 |
| 2015 July | 247 | 18 | 265 |
| 2015 June | 146 | 4 | 150 |
| 2015 May | 150 | 20 | 170 |
| 2015 April | 149 | 16 | 165 |
| 2015 March | 131 | 6 | 137 |
| 2015 February | 141 | 10 | 151 |
| 2015 January | 150 | 9 | 159 |
| 2014 December | 178 | 8 | 186 |
| 2014 November | 178 | 9 | 187 |
| 2014 October | 249 | 12 | 261 |
| 2014 September | 138 | 11 | 149 |
| 2014 August | 107 | 22 | 129 |
| 2014 July | 109 | 14 | 123 |
| 2014 June | 114 | 9 | 123 |
| 2014 May | 106 | 17 | 123 |
| 2014 April | 114 | 11 | 125 |
| 2014 March | 118 | 11 | 129 |
| 2014 February | 85 | 12 | 97 |
| 2014 January | 62 | 12 | 74 |
| 2013 December | 67 | 13 | 80 |
| 2013 November | 62 | 8 | 70 |
| 2013 October | 56 | 13 | 69 |
| 2013 September | 62 | 22 | 84 |
| 2013 August | 88 | 14 | 102 |
| 2013 July | 63 | 15 | 78 |
| 2013 June | 68 | 10 | 78 |
| 2013 May | 51 | 9 | 60 |
| 2013 April | 44 | 7 | 51 |
| 2013 March | 13 | 4 | 17 |
Show all
