Correspondence: Dr F. Barbé Servei de Pneumologia, Hospital Universitari Arnau de Vilanova Rovira Roure, 8025198 Lleida, Spain
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Barbé Servei de Pneumologia, Hospital Universitari Arnau de Vilanova Rovira Roure, 8025198 Lleida, Spain" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2007-04-17" "fechaAceptado" => "2008-05-20" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec155139" "palabras" => array:3 [ 0 => "<span class="elsevierStyleItalic">Sex</span>" 1 => "<span class="elsevierStyleItalic">Polysomnography</span>" 2 => "<span class="elsevierStyleItalic">Sleep apnea syndrome</span>" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec155138" "palabras" => array:3 [ 0 => "<span class="elsevierStyleItalic">Sexo</span>" 1 => "<span class="elsevierStyleItalic">Polisomnografía</span>" 2 => "<span class="elsevierStyleItalic">Síndrome de apneas del sueño</span>" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">The aim of this study was to compare the clinical, anthropometric, and polysomnographic characteristics of a broad group of patients with sleep apnea-hypopnea syndrome according to sex.</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p class="elsevierStyleSimplePara elsevierViewall">The study, conducted in 6 Spanish university hospitals, included consecutive patients attended from 2003 through 2005 with an apnea-hypopnea index greater than 5. Groups were formed according to sex and then stratified into age subgroups of younger (≤ 45 years) and older patients (>45 years) for further comparison.</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">The study included 2464 men and 424 women. Women were older (mean [SD] age, 56 [12] years vs 51 [12] years), weighed more (body mass index, 31 [6] kg/m<span class="elsevierStyleSup">2</span> vs 30 [5] kg/m<span class="elsevierStyleSup">2</span>), and had a larger hip circumference (119 [15] cm vs 111 [12] cm) and smaller neck circumference (38 [3] cm vs 42 [9] cm) than men (<span class="elsevierStyleItalic">P</span><.001 in all cases). The degree of daytime sleepiness (Epworth scale) and the apnea-hypopnea index were similar in both groups, although women had a longer sleep latency (23[28] minutes vs 27 [32] minutes; <span class="elsevierStyleItalic">P</span><.004) and a higher mean oxygen saturation (92% [4%] vs 91% [5%]) and minimum oxygen saturation (78% [11%] vs 75% [12%]; <span class="elsevierStyleItalic">P</span><.0001) than men. On stratification by age, only weight differences between men and women were observed in the younger group whereas the older group also showed differences in oxygen saturation during sleep.</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">Women with sleep apnea-hypopnea are more overweight than men and tend to seek medical attention at an older age. The clinical and polysomnographic variables were generally similar for men and women—the only differences were that sleep latency was longer and hypoxemia during sleep was more accentuated in women.</p>" ] "es" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">Comparar, en una cohorte amplia de pacientes con síndrome de apneas-hipopneas durante el sueño, las características clínicas, antropométricas y polisomnográficas en función del sexo.</p> <span class="elsevierStyleSectionTitle">Pacientes y métodos</span><p class="elsevierStyleSimplePara elsevierViewall">En el estudio, realizado en 6 hospitales universitarios españoles, se incluyó a pacientes consecutivos con un índice de apneas-hipopneas del sueño mayor de 5 h<span class="elsevierStyleSup">−1</span>, que fueron evaluados entre 2003 y 2005. Se dividieron en función del sexo y, posteriormente, en función de la edad: pacientes jóvenes (≤ 45 años) y adultos (> 45 años).</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Se ha estudiado a 2.464 varones y 424 mujeres. Las mujeres eran mayores (edad media ± desviación estándar: 56 ± 12 frente a 51 ± 12 años; p < 0,0001), pesaban más (índice de masa corporal: 31 ± 6 frente a 30 ± 5 kg/m<span class="elsevierStyleSup">2</span>; p < 0,0001) y presentaban una mayor circunferencia de cadera (119 ± 15 frente a 111 ± 12 cm; p < 0,0001) y una menor circunferencia de cuello (38 ± 3 frente a 42 ± 9 cm; p < 0,0001) que los varones. El grado de somnolencia diurna (escala de Epworth) y el índice de apneas-hipopneas eran similares en ambos grupos, aunque el de mujeres presentaba una latencia de sueño más larga (23 ± 28 frente a 27 ± 32 min; p < 0,004) y una saturación de oxígeno media (un 92 ± 4 frente a un 91 ± 5%) y mínima menor (un 78 ± 11 frente a un 75 ± 12%; p < 0,0001) que los varones. Al diferenciar los grupos por edad, en el grupo de jóvenes sólo se mantenían las diferencias ponderales, mientras que entre los adultos reaparecían las diferencias en los valores de saturación nocturna.</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">Las mujeres con síndrome de apneas-hipopneas durante el sueño son más obesas que los varones y consultan a una edad más avanzada. Desde el punto de vista clínico y polisomnográfico, no hay grandes diferencias en función del sexo. Únicamente la latencia de sueño es superior y la hipoxemia nocturna más acentuada.</p>" ] ] "NotaPie" => array:1 [ 0 => array:1 [ "nota" => "<p class="elsevierStyleNotepara">Study financed by the Spanish Health Research Fund (Fondo de Investigaciones Sanitarias de España) (Grant 0300022*), the National Institute for Health (Grant HL65270), the Children's Foundation Endowment for Sleep Research, an award from the Commonwealth of Kentucky Challenge for Excellence Trust Fund to David Gozal, and the CIBER for Respiratory Diseases (CibeRes).</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:16 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Documento de consenso nacional sobre el síndrome de apneas-hipopneas del sueño (SAHS)" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "Grupo Español de Sueño (GES)" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Bronconeumol" "fecha" => "2005" "volumen" => "41" "numero" => "Suppl 4" "paginaInicial" => "12" "paginaFinal" => "29" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The occurrence of sleep-disordered breathing among middle-aged adults" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "T Young" 1 => "M Palta" 2 => "J Dempsey" 3 => "J Skatrud" 4 => "S Weber" 5 => "S Badr" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1056/NEJM199304293281704" "Revista" => array:6 [ "tituloSerie" => "N Engl J Med" "fecha" => "1993" "volumen" => "328" "paginaInicial" => "1230" "paginaFinal" => "1235" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8464434" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib3" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Prevalence of sleep-disordered breathing in women – effects of gender" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "EO Bixler" 1 => "AN Vgontzas" 2 => "HM Lin" 3 => "T Ten Have" 4 => "J Rein" 5 => "A Vela-Bueno" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/ajrccm.163.3.9911064" "Revista" => array:6 [ "tituloSerie" => "Am J Respir Crit Care Med" "fecha" => "2001" "volumen" => "163" "paginaInicial" => "608" "paginaFinal" => "613" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11254512" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib4" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Obstructive sleep apneahypopnea and related clinical features in a population-based sample of subjects aged 30 to 70 yr" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "J Durán" 1 => "S Esnaola" 2 => "R Rubio" 3 => "A Iztueta" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/ajrccm.163.3.2005065" "Revista" => array:6 [ "tituloSerie" => "Am J Respir Crit Care Med" "fecha" => "2001" "volumen" => "163" "paginaInicial" => "685" "paginaFinal" => "689" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11254524" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib5" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Gender differences in sleep disordered breathing in a community-based sample" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "S Redline" 1 => "K Kump" 2 => "PV Tishler" 3 => "I Browner" 4 => "V Ferrette" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/ajrccm.149.3.8118642" "Revista" => array:6 [ "tituloSerie" => "Am J Respir Crit Care Med" "fecha" => "1994" "volumen" => "149" "paginaInicial" => "722" "paginaFinal" => "726" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8118642" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib6" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Sleep apnea, hypopnea and oxygen desaturation in normal subjects. 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Year/Month | Html | Total | |
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2019 January | 6 | 10 | 16 |
2018 December | 9 | 9 | 18 |
2018 November | 18 | 18 | 36 |
2018 October | 15 | 16 | 31 |
2018 September | 8 | 7 | 15 |
2018 May | 5 | 0 | 5 |
2018 April | 8 | 6 | 14 |
2018 March | 6 | 4 | 10 |
2018 February | 4 | 8 | 12 |
2018 January | 5 | 3 | 8 |
2017 December | 5 | 12 | 17 |
2017 November | 4 | 5 | 9 |
2017 October | 4 | 7 | 11 |
2017 September | 5 | 7 | 12 |
2017 August | 7 | 8 | 15 |
2017 June | 9 | 11 | 20 |
2017 May | 7 | 6 | 13 |
2017 April | 4 | 3 | 7 |
2017 March | 4 | 1 | 5 |
2017 February | 2 | 1 | 3 |
2017 January | 4 | 2 | 6 |
2016 December | 8 | 11 | 19 |
2016 November | 12 | 10 | 22 |
2016 October | 20 | 11 | 31 |
2016 September | 16 | 5 | 21 |
2016 August | 7 | 2 | 9 |
2016 July | 10 | 0 | 10 |
2016 March | 1 | 0 | 1 |
2016 February | 1 | 0 | 1 |
2015 December | 2 | 0 | 2 |
2015 October | 55 | 9 | 64 |
2015 September | 58 | 11 | 69 |
2015 August | 29 | 10 | 39 |
2015 July | 44 | 10 | 54 |
2015 June | 40 | 3 | 43 |
2015 May | 46 | 11 | 57 |
2015 April | 36 | 11 | 47 |
2015 March | 33 | 6 | 39 |
2015 February | 52 | 3 | 55 |
2015 January | 42 | 7 | 49 |
2014 December | 41 | 6 | 47 |
2014 November | 42 | 7 | 49 |
2014 October | 49 | 8 | 57 |
2014 September | 37 | 15 | 52 |
2014 August | 35 | 10 | 45 |
2014 July | 44 | 6 | 50 |
2014 June | 53 | 13 | 66 |
2014 May | 51 | 12 | 63 |
2014 April | 50 | 6 | 56 |
2014 March | 65 | 11 | 76 |
2014 February | 58 | 12 | 70 |
2014 January | 45 | 15 | 60 |
2013 December | 37 | 8 | 45 |
2013 November | 56 | 7 | 63 |
2013 October | 56 | 9 | 65 |
2013 September | 51 | 10 | 61 |
2013 August | 54 | 9 | 63 |
2013 July | 42 | 9 | 51 |
2013 June | 40 | 7 | 47 |
2013 May | 34 | 5 | 39 |
2013 April | 18 | 7 | 25 |
2013 March | 6 | 1 | 7 |