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        "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">To assess the cost-effectiveness of automatic continuous positive airway pressure &#40;CPAP&#41; titration at home on 1 night or 2 consecutive nights in patients with the sleep apnea-hypopnea syndrome &#40;SAHS&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p class="elsevierStyleSimplePara elsevierViewall">A home titration study was performed using automatic CPAP for 2 consecutive nights on 100 patients with SAHS and an indication for CPAP&#46; The number of successful studies and the costs of the first night and both nights were analyzed&#46; The pressure requirements on each night and the agreement between the pressures selected visually by 2 different observers were compared&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">CPAP titration was successful in 85&#37; and 80&#37; of patients on the first night and second night&#44; respectively&#44; and in 88&#37; of patients after both nights&#46; No significant differences between the 2 nights were found for the following parameters&#58; 95th percentile pressure &#40;mean &#91;SD&#93;&#44; 10&#46;2 &#91;1&#46;8&#93; cm H<span class="elsevierStyleInf">2</span>O and 10&#46;2 &#91;1&#46;6&#93; cm H<span class="elsevierStyleInf">2</span>O on the first and second nights&#44; respectively&#41;&#44; mean pressure &#40;7&#46;8 &#91;1&#46;7&#93; cm H<span class="elsevierStyleInf">2</span>O and 7&#46;7 &#91;1&#46;7&#93; cm H<span class="elsevierStyleInf">2</span>O&#41;&#44; or the pressure selected visually &#40;9&#46;4 &#91;1&#46;5&#93; cm H<span class="elsevierStyleInf">2</span>O and 9&#46;4 &#91;1&#46;4&#93; cm H<span class="elsevierStyleInf">2</span>O&#41;&#46; Interobserver agreement on the pressure selected was good&#58; the &#954; statistics were 0&#46;956 for the first night and 0&#46;91 for the second night&#46; The 1-night study cost &#8364;232&#46;63 and the 2-night study cost &#8364;227&#46;93&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">Automatic CPAP titration at home for 1 night enables a substantially greater number of patients to be studied at a similar cost than is possible when titration is accomplished in 2 consecutive nights&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">Evaluar el coste-eficacia de la graduaci&#243;n autom&#225;tica de la presi&#243;n positiva continua de la v&#237;a a&#233;rea &#40;CPAP&#41; en el domicilio&#44; en una y 2 noches consecutivas&#44; en pacientes con s&#237;ndrome de apneas-hiponeas durante el sue&#241;o&#46;</p> <span class="elsevierStyleSectionTitle">Pacientes y m&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">Se practic&#243; un estudio de graduaci&#243;n domiciliaria con un equipo de CPAP autom&#225;tica &#40;APAP&#41; durante 2 noches consecutivas a 100 pacientes con s&#237;ndrome de apneas-hipopneas durante el sue&#241;o e indicaci&#243;n de tratamiento con CPAP&#46; Se evaluaron el n&#250;mero de estudios satisfactorios y el coste resultante de la primera noche y de las 2 noches&#46; Se compararon las necesidades de presi&#243;n durante cada noche y la concordancia entre la presi&#243;n seleccionada visualmente por 2 observadores&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">La graduaci&#243;n de CPAP fue satisfactoria en el 85 y el 80&#37; de los pacientes en la primera y la segunda noches&#44; respectivamente&#44; y en el 88&#37; despu&#233;s de las 2 noches&#46; No hubo diferencias significativas entre las 2 noches en la presi&#243;n percentil 95&#37; &#40;media &#177; desviaci&#243;n est&#225;ndar&#58; 10&#44;2 &#177; 1&#44;8 y 10&#44;2 &#177; 1&#44;6 cmH<span class="elsevierStyleInf">2</span>O&#41;&#44; la presi&#243;n media &#40;7&#44;8 &#177; 1&#44;7 y 7&#44;7 &#177; 1&#44;7 cmH<span class="elsevierStyleInf">2</span>O&#41; y la presi&#243;n visual &#40;9&#44;4 &#177; 1&#44;5 y 9&#44;4 &#177; 1&#44;4 cmH<span class="elsevierStyleInf">2</span>O&#41;&#46; Se obtuvo un buen grado de concordancia entre 2 observadores en la selecci&#243;n de presi&#243;n &#40;kappa &#61; 0&#44;956 para la noche 1&#59; kappa &#61; 0&#44;91 para la noche 2&#41;&#46; El coste de los estudios fue 232&#44;63 &#8364; para la primera noche y 227&#44;93 &#8364; para las 2 noches consecutivas&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">Con un coste similar&#44; la adopci&#243;n de un protocolo de graduaci&#243;n autom&#225;tica de la CPAP una noche en el domicilio permite incrementar sustancialmente el n&#250;mero de pacientes estudiados&#44; respecto a 2 noches consecutivas&#46;</p>"
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Original Articles
Cost-Effectiveness Analysis of Automatic Titration of Continuous Positive Airway Pressure at Home in 1 Night Versus 2 Nights
Nicolás Roldána,b, Gabriel Sampola,b, Teresa Sagalésc, Odile Romeroc, María José Juradoc, José Ríosd, Patricia Lloberesa,b,
Corresponding author
plloberes@vhebron.net

Correspondence: Dr P. Lloberes Servei de Pneumologia, Hospital Universitari Vall d'Hebron Pg. Vall d'Hebron, 119-12908035 Barcelona, Spain
a Servei de Pneumologia, Hospital Universitari Vall d'Hebron, Barcelona, Spain
b CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain
c Servei de Neurofisiología, Hospital Universitari Vall d'Hebron, Barcelona, Spain
d Laboratorio de Bioestadística y Epidemiología, Universitat Autònoma de Barcelona, Barcelona, Spain
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">To assess the cost-effectiveness of automatic continuous positive airway pressure &#40;CPAP&#41; titration at home on 1 night or 2 consecutive nights in patients with the sleep apnea-hypopnea syndrome &#40;SAHS&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p class="elsevierStyleSimplePara elsevierViewall">A home titration study was performed using automatic CPAP for 2 consecutive nights on 100 patients with SAHS and an indication for CPAP&#46; The number of successful studies and the costs of the first night and both nights were analyzed&#46; The pressure requirements on each night and the agreement between the pressures selected visually by 2 different observers were compared&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">CPAP titration was successful in 85&#37; and 80&#37; of patients on the first night and second night&#44; respectively&#44; and in 88&#37; of patients after both nights&#46; No significant differences between the 2 nights were found for the following parameters&#58; 95th percentile pressure &#40;mean &#91;SD&#93;&#44; 10&#46;2 &#91;1&#46;8&#93; cm H<span class="elsevierStyleInf">2</span>O and 10&#46;2 &#91;1&#46;6&#93; cm H<span class="elsevierStyleInf">2</span>O on the first and second nights&#44; respectively&#41;&#44; mean pressure &#40;7&#46;8 &#91;1&#46;7&#93; cm H<span class="elsevierStyleInf">2</span>O and 7&#46;7 &#91;1&#46;7&#93; cm H<span class="elsevierStyleInf">2</span>O&#41;&#44; or the pressure selected visually &#40;9&#46;4 &#91;1&#46;5&#93; cm H<span class="elsevierStyleInf">2</span>O and 9&#46;4 &#91;1&#46;4&#93; cm H<span class="elsevierStyleInf">2</span>O&#41;&#46; Interobserver agreement on the pressure selected was good&#58; the &#954; statistics were 0&#46;956 for the first night and 0&#46;91 for the second night&#46; The 1-night study cost &#8364;232&#46;63 and the 2-night study cost &#8364;227&#46;93&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">Automatic CPAP titration at home for 1 night enables a substantially greater number of patients to be studied at a similar cost than is possible when titration is accomplished in 2 consecutive nights&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">Evaluar el coste-eficacia de la graduaci&#243;n autom&#225;tica de la presi&#243;n positiva continua de la v&#237;a a&#233;rea &#40;CPAP&#41; en el domicilio&#44; en una y 2 noches consecutivas&#44; en pacientes con s&#237;ndrome de apneas-hiponeas durante el sue&#241;o&#46;</p> <span class="elsevierStyleSectionTitle">Pacientes y m&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">Se practic&#243; un estudio de graduaci&#243;n domiciliaria con un equipo de CPAP autom&#225;tica &#40;APAP&#41; durante 2 noches consecutivas a 100 pacientes con s&#237;ndrome de apneas-hipopneas durante el sue&#241;o e indicaci&#243;n de tratamiento con CPAP&#46; Se evaluaron el n&#250;mero de estudios satisfactorios y el coste resultante de la primera noche y de las 2 noches&#46; Se compararon las necesidades de presi&#243;n durante cada noche y la concordancia entre la presi&#243;n seleccionada visualmente por 2 observadores&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">La graduaci&#243;n de CPAP fue satisfactoria en el 85 y el 80&#37; de los pacientes en la primera y la segunda noches&#44; respectivamente&#44; y en el 88&#37; despu&#233;s de las 2 noches&#46; No hubo diferencias significativas entre las 2 noches en la presi&#243;n percentil 95&#37; &#40;media &#177; desviaci&#243;n est&#225;ndar&#58; 10&#44;2 &#177; 1&#44;8 y 10&#44;2 &#177; 1&#44;6 cmH<span class="elsevierStyleInf">2</span>O&#41;&#44; la presi&#243;n media &#40;7&#44;8 &#177; 1&#44;7 y 7&#44;7 &#177; 1&#44;7 cmH<span class="elsevierStyleInf">2</span>O&#41; y la presi&#243;n visual &#40;9&#44;4 &#177; 1&#44;5 y 9&#44;4 &#177; 1&#44;4 cmH<span class="elsevierStyleInf">2</span>O&#41;&#46; Se obtuvo un buen grado de concordancia entre 2 observadores en la selecci&#243;n de presi&#243;n &#40;kappa &#61; 0&#44;956 para la noche 1&#59; kappa &#61; 0&#44;91 para la noche 2&#41;&#46; El coste de los estudios fue 232&#44;63 &#8364; para la primera noche y 227&#44;93 &#8364; para las 2 noches consecutivas&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">Con un coste similar&#44; la adopci&#243;n de un protocolo de graduaci&#243;n autom&#225;tica de la CPAP una noche en el domicilio permite incrementar sustancialmente el n&#250;mero de pacientes estudiados&#44; respecto a 2 noches consecutivas&#46;</p>"
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ISSN: 15792129
Original language: English
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Archivos de Bronconeumología

Are you a health professional able to prescribe or dispense drugs?