Correspondencia: Dr J. de Miguel Díez Servicio de Neumología Hospital Universitario Gregorio Marañón Dr. Esquerdo, 46 28007 Madrid, Spain
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"aff2" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor1" ] ] ] 2 => array:3 [ "nombre" => "José Luis" "apellidos" => "Álvarez-Sala" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff3" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Servicio de Oncología Médica, Hospital Universitario Gregorio Marañón, Departamento de Fisiología, Facultad de Medicina, Universidad Autónoma de Madrid, Madrid, Spain" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:3 [ "entidad" => "Servicio de Neumología, Hospital Universitario Gregorio Marañón, Universidad Complutense de Madrid, Madrid, Spain" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] 2 => array:3 [ "entidad" => "Servicio de Neumología, Hospital Clínico San Carlos, Universidad Complutense de Madrid, Madrid, Spain" "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff3" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "*" "correspondencia" => "Correspondencia: Dr J. de Miguel Díez Servicio de Neumología Hospital Universitario Gregorio Marañón Dr. Esquerdo, 46 28007 Madrid, Spain" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2007-10-22" "fechaAceptado" => "2007-11-07" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec155401" "palabras" => array:3 [ 0 => "Solitary pulmonary nodule" 1 => "Positron emission tomography" 2 => "Diagnostic yield" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec155402" "palabras" => array:3 [ 0 => "Nódulo pulmonar solitario" 1 => "Tomografía por emisión de positrones" 2 => "Rentabilidad diagnóstica" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:1 [ "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">Solitary pulmonary nodules are a major clinical challenge for all doctors involved in their study. The aim is always to avoid missing malignant lesions but also to avoid performing unnecessary diagnostic tests. The most recent research suggests that in the near future chest computed tomography will become even more widely used for the early detection of lung cancer. If this occurs, there is likely to be a marked increase in the number of solitary pulmonary nodules detected, making it essential to develop techniques that enable us to manage this problem with an optimal risk-benefit ratio. We review the underlying principles of positron emission tomography and the advances that have been made in its use for the study of solitary pulmonary nodules. In addition, we discuss the possible causes of false positives and negatives in this technique and the strategies aimed at increasing diagnostic yield.</p>" ] "es" => array:1 [ "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">El nódulo pulmonar solitario (NPS) es un reto clínico importante para todo médico implicado en su estudio. El objetivo se cifra siempre en impedir que una lesión maligna pase inadvertida, pero también en evitar que se realicen pruebas diagnósticas innecesarias. Si en el futuro inmediato se generaliza todavía más, como parecen indicar las investigaciones más recientes, el uso de la tomografía computarizada de tórax como método de detección precoz del cáncer de pulmón, es probable que se produzca un notable aumento del número de NPS diagnosticados. En tal caso se haría imprescindible desarrollar técnicas que permitan abordar este problema con una óptima relación riesgo-beneficio. En este trabajo se revisan los fundamentos y los avances que se han producido en el uso de la tomografía por emisión de positrones como técnica de estudio del NPS. Se discuten, asimismo, las causas que explican los posibles falsos positivos y negativos de la prueba, así como las estrategias dirigidas a incrementar la rentabilidad diagnóstica de este procedimiento.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:29 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The solitary pulmonary nodule" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "D Ost" 1 => "AM Fein" 2 => "SH Feinsilver" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1056/NEJMcp012290" "Revista" => array:6 [ "tituloSerie" => "N Engl J Med" "fecha" => "2003" "volumen" => "348" "paginaInicial" => "2535" "paginaFinal" => "2542" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12815140" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Evaluation of the solitary pulmonary nodule by positron emission tomography imaging" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "T Bury" 1 => "A Dowlati" 2 => "P Paulus" 3 => "JL Corhay" 4 => "T Benoit" 5 => "JM Kayembe" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Eur Respir J" "fecha" => "1996" "volumen" => "9" "paginaInicial" => "410" "paginaFinal" => "414" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8729997" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib3" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The probability of malignancy in solitary pulmonary nodules. 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Year/Month | Html | Total | |
---|---|---|---|
2024 November | 6 | 3 | 9 |
2024 October | 29 | 15 | 44 |
2024 September | 24 | 15 | 39 |
2024 August | 40 | 31 | 71 |
2024 July | 23 | 26 | 49 |
2024 June | 40 | 32 | 72 |
2024 May | 40 | 35 | 75 |
2024 April | 17 | 26 | 43 |
2024 March | 21 | 15 | 36 |
2024 February | 15 | 16 | 31 |
2023 March | 3 | 2 | 5 |
2023 February | 22 | 20 | 42 |
2023 January | 16 | 25 | 41 |
2022 December | 22 | 30 | 52 |
2022 November | 19 | 26 | 45 |
2022 October | 18 | 34 | 52 |
2022 September | 20 | 21 | 41 |
2022 August | 16 | 31 | 47 |
2022 July | 19 | 41 | 60 |
2022 June | 16 | 33 | 49 |
2022 May | 16 | 22 | 38 |
2022 April | 15 | 32 | 47 |
2022 March | 14 | 34 | 48 |
2022 February | 14 | 34 | 48 |
2022 January | 10 | 30 | 40 |
2021 December | 13 | 50 | 63 |
2021 November | 18 | 54 | 72 |
2021 October | 21 | 56 | 77 |
2021 September | 18 | 63 | 81 |
2021 August | 15 | 29 | 44 |
2021 July | 7 | 32 | 39 |
2021 June | 12 | 35 | 47 |
2021 May | 10 | 27 | 37 |
2021 April | 20 | 69 | 89 |
2021 March | 13 | 21 | 34 |
2021 February | 13 | 20 | 33 |
2021 January | 9 | 14 | 23 |
2020 December | 8 | 11 | 19 |
2020 November | 5 | 15 | 20 |
2020 October | 5 | 13 | 18 |
2020 September | 4 | 3 | 7 |
2020 August | 9 | 13 | 22 |
2020 July | 12 | 17 | 29 |
2020 June | 6 | 4 | 10 |
2020 May | 14 | 12 | 26 |
2020 April | 20 | 18 | 38 |
2020 March | 11 | 13 | 24 |
2020 February | 22 | 15 | 37 |
2020 January | 14 | 16 | 30 |
2019 December | 10 | 15 | 25 |
2019 November | 11 | 12 | 23 |
2019 October | 6 | 7 | 13 |
2019 September | 6 | 7 | 13 |
2019 August | 12 | 13 | 25 |
2019 July | 9 | 26 | 35 |
2019 June | 7 | 7 | 14 |
2019 May | 10 | 9 | 19 |
2019 April | 14 | 37 | 51 |
2019 March | 11 | 11 | 22 |
2019 February | 7 | 8 | 15 |
2019 January | 5 | 7 | 12 |
2018 December | 10 | 9 | 19 |
2018 November | 16 | 12 | 28 |
2018 October | 13 | 14 | 27 |
2018 September | 11 | 5 | 16 |
2018 May | 2 | 0 | 2 |
2018 April | 8 | 8 | 16 |
2018 March | 5 | 5 | 10 |
2018 February | 2 | 5 | 7 |
2018 January | 3 | 5 | 8 |
2017 December | 3 | 4 | 7 |
2017 November | 2 | 4 | 6 |
2017 October | 5 | 6 | 11 |
2017 September | 8 | 8 | 16 |
2017 August | 9 | 12 | 21 |
2017 July | 6 | 5 | 11 |
2017 June | 7 | 12 | 19 |
2017 May | 5 | 3 | 8 |
2017 April | 6 | 5 | 11 |
2017 March | 9 | 4 | 13 |
2017 February | 4 | 6 | 10 |
2017 January | 4 | 4 | 8 |
2016 December | 4 | 6 | 10 |
2016 November | 4 | 4 | 8 |
2016 October | 12 | 11 | 23 |
2016 September | 6 | 11 | 17 |
2016 August | 8 | 4 | 12 |
2016 July | 7 | 3 | 10 |
2016 March | 2 | 0 | 2 |
2016 February | 1 | 0 | 1 |
2015 December | 2 | 0 | 2 |
2015 October | 42 | 12 | 54 |
2015 September | 63 | 8 | 71 |
2015 August | 58 | 11 | 69 |
2015 July | 88 | 6 | 94 |
2015 June | 43 | 2 | 45 |
2015 May | 53 | 3 | 56 |
2015 April | 50 | 9 | 59 |
2015 March | 48 | 7 | 55 |
2015 February | 37 | 0 | 37 |
2015 January | 37 | 5 | 42 |
2014 December | 43 | 4 | 47 |
2014 November | 50 | 4 | 54 |
2014 October | 54 | 6 | 60 |
2014 September | 38 | 4 | 42 |
2014 August | 59 | 9 | 68 |
2014 July | 39 | 7 | 46 |
2014 June | 76 | 8 | 84 |
2014 May | 51 | 10 | 61 |
2014 April | 65 | 4 | 69 |
2014 March | 77 | 9 | 86 |
2014 February | 77 | 9 | 86 |
2014 January | 45 | 9 | 54 |
2013 December | 52 | 8 | 60 |
2013 November | 46 | 7 | 53 |
2013 October | 51 | 9 | 60 |
2013 September | 59 | 10 | 69 |
2013 August | 48 | 5 | 53 |
2013 July | 53 | 17 | 70 |
2013 June | 42 | 10 | 52 |
2013 May | 43 | 9 | 52 |
2013 April | 18 | 5 | 23 |
2013 March | 6 | 2 | 8 |