array:23 [
  "pii" => "S1579212908600890"
  "issn" => "15792129"
  "doi" => "10.1016/S1579-2129(08)60089-0"
  "estado" => "S300"
  "fechaPublicacion" => "2008-01-01"
  "aid" => "60089"
  "copyright" => "Sociedad Española de Neumología y Cirugía Torácica (SEPAR)"
  "copyrightAnyo" => "2008"
  "documento" => "article"
  "crossmark" => 0
  "subdocumento" => "rev"
  "cita" => "Arch Bronconeumol. 2008;44:493-8"
  "abierto" => array:3 [
    "ES" => false
    "ES2" => false
    "LATM" => false
  ]
  "gratuito" => false
  "lecturas" => array:2 [
    "total" => 2622
    "formatos" => array:3 [
      "EPUB" => 108
      "HTML" => 1926
      "PDF" => 588
    ]
  ]
  "itemSiguiente" => array:18 [
    "pii" => "S1579212908600907"
    "issn" => "15792129"
    "doi" => "10.1016/S1579-2129(08)60090-7"
    "estado" => "S300"
    "fechaPublicacion" => "2008-01-01"
    "aid" => "60090"
    "copyright" => "Sociedad Española de Neumología y Cirugía Torácica (SEPAR)"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "sco"
    "cita" => "Arch Bronconeumol. 2008;44:499-503"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 6053
      "formatos" => array:3 [
        "EPUB" => 117
        "HTML" => 5065
        "PDF" => 871
      ]
    ]
    "en" => array:10 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Case Reports</span>"
      "titulo" => "Desquamative Interstitial Pneumonia and Respiratory Bronchiolitis-Associated Interstitial Lung Disease&#58; Data From the Spanish Patient Registry"
      "tienePdf" => "en"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "499"
          "paginaFinal" => "503"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Adolfo Baloira, Antoni Xaubet, Eulogio Rodr&#237;guez Becerra, Ana Dolores Romero, &#193;lvaro Casanova, Julio Ancochea"
          "autores" => array:6 [
            0 => array:2 [
              "nombre" => "Adolfo"
              "apellidos" => "Baloira"
            ]
            1 => array:2 [
              "nombre" => "Antoni"
              "apellidos" => "Xaubet"
            ]
            2 => array:2 [
              "nombre" => "Eulogio"
              "apellidos" => "Rodr&#237;guez Becerra"
            ]
            3 => array:2 [
              "nombre" => "Ana Dolores"
              "apellidos" => "Romero"
            ]
            4 => array:2 [
              "nombre" => "&#193;lvaro"
              "apellidos" => "Casanova"
            ]
            5 => array:2 [
              "nombre" => "Julio"
              "apellidos" => "Ancochea"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212908600907?idApp=UINPBA00003Z"
    "url" => "/15792129/0000004400000009/v1_201305150400/S1579212908600907/v1_201305150400/en/main.assets"
  ]
  "itemAnterior" => array:18 [
    "pii" => "S1579212908600889"
    "issn" => "15792129"
    "doi" => "10.1016/S1579-2129(08)60088-9"
    "estado" => "S300"
    "fechaPublicacion" => "2008-01-01"
    "aid" => "60088"
    "copyright" => "Sociedad Espa&#241;ola de Neumolog&#237;a y Cirug&#237;a Tor&#225;cica &#40;SEPAR&#41;"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Arch Bronconeumol. 2008;44:489-92"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 2150
      "formatos" => array:3 [
        "EPUB" => 101
        "HTML" => 1403
        "PDF" => 646
      ]
    ]
    "en" => array:8 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Special Article</span>"
      "titulo" => "CIBER of Respiratory Diseases &#40;CibeRes&#41;"
      "tienePdf" => "en"
      "tieneTextoCompleto" => 0
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "489"
          "paginaFinal" => "492"
        ]
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "&#192;lvar Agust&#237;, Francisco Pozo, Paloma Vaquer"
          "autores" => array:3 [
            0 => array:2 [
              "nombre" => "&#192;lvar"
              "apellidos" => "Agust&#237;"
            ]
            1 => array:2 [
              "nombre" => "Francisco"
              "apellidos" => "Pozo"
            ]
            2 => array:2 [
              "nombre" => "Paloma"
              "apellidos" => "Vaquer"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212908600889?idApp=UINPBA00003Z"
    "url" => "/15792129/0000004400000009/v1_201305150400/S1579212908600889/v1_201305150400/en/main.assets"
  ]
  "en" => array:14 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Review Article</span>"
    "titulo" => "Positron Emission Tomography for the Study of Solitary Pulmonary Nodules"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "493"
        "paginaFinal" => "498"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "Iv&#225;n M&#225;rquez Rodas, Javier de Miguel D&#237;ez, Jos&#233; Luis &#193;lvarez-Sala"
        "autores" => array:3 [
          0 => array:3 [
            "nombre" => "Iv&#225;n"
            "apellidos" => "M&#225;rquez Rodas"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff1"
              ]
            ]
          ]
          1 => array:4 [
            "nombre" => "Javier"
            "apellidos" => "de Miguel D&#237;ez"
            "email" => array:1 [
              0 => "jmiguel&#46;hgugm&#64;salud&#46;madrid&#46;org"
            ]
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff2"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor1"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "Jos&#233; Luis"
            "apellidos" => "&#193;lvarez-Sala"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">c</span>"
                "identificador" => "aff3"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:3 [
          0 => array:3 [
            "entidad" => "Servicio de Oncolog&#237;a M&#233;dica&#44; Hospital Universitario Gregorio Mara&#241;&#243;n&#44; Departamento de Fisiolog&#237;a&#44; Facultad de Medicina&#44; Universidad Aut&#243;noma de Madrid&#44; Madrid&#44; Spain"
            "etiqueta" => "<span class="elsevierStyleSup">a</span>"
            "identificador" => "aff1"
          ]
          1 => array:3 [
            "entidad" => "Servicio de Neumolog&#237;a&#44; Hospital Universitario Gregorio Mara&#241;&#243;n&#44; Universidad Complutense de Madrid&#44; Madrid&#44; Spain"
            "etiqueta" => "<span class="elsevierStyleSup">b</span>"
            "identificador" => "aff2"
          ]
          2 => array:3 [
            "entidad" => "Servicio de Neumolog&#237;a&#44; Hospital Cl&#237;nico San Carlos&#44; Universidad Complutense de Madrid&#44; Madrid&#44; Spain"
            "etiqueta" => "<span class="elsevierStyleSup">c</span>"
            "identificador" => "aff3"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor1"
            "etiqueta" => "&#42;"
            "correspondencia" => "Correspondencia&#58; Dr J&#46; de Miguel D&#237;ez Servicio de Neumolog&#237;a Hospital Universitario Gregorio Mara&#241;&#243;n Dr&#46; Esquerdo&#44; 46 28007 Madrid&#44; Spain"
          ]
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2007-10-22"
    "fechaAceptado" => "2007-11-07"
    "PalabrasClave" => array:2 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Key words"
          "identificador" => "xpalclavsec155401"
          "palabras" => array:3 [
            0 => "Solitary pulmonary nodule"
            1 => "Positron emission tomography"
            2 => "Diagnostic yield"
          ]
        ]
      ]
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec155402"
          "palabras" => array:3 [
            0 => "N&#243;dulo pulmonar solitario"
            1 => "Tomograf&#237;a por emisi&#243;n de positrones"
            2 => "Rentabilidad diagn&#243;stica"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "en" => array:1 [
        "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">Solitary pulmonary nodules are a major clinical challenge for all doctors involved in their study&#46; The aim is always to avoid missing malignant lesions but also to avoid performing unnecessary diagnostic tests&#46; The most recent research suggests that in the near future chest computed tomography will become even more widely used for the early detection of lung cancer&#46; If this occurs&#44; there is likely to be a marked increase in the number of solitary pulmonary nodules detected&#44; making it essential to develop techniques that enable us to manage this problem with an optimal risk-benefit ratio&#46; We review the underlying principles of positron emission tomography and the advances that have been made in its use for the study of solitary pulmonary nodules&#46; In addition&#44; we discuss the possible causes of false positives and negatives in this technique and the strategies aimed at increasing diagnostic yield&#46;</p>"
      ]
      "es" => array:1 [
        "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">El n&#243;dulo pulmonar solitario &#40;NPS&#41; es un reto cl&#237;nico importante para todo m&#233;dico implicado en su estudio&#46; El objetivo se cifra siempre en impedir que una lesi&#243;n maligna pase inadvertida&#44; pero tambi&#233;n en evitar que se realicen pruebas diagn&#243;sticas innecesarias&#46; Si en el futuro inmediato se generaliza todav&#237;a m&#225;s&#44; como parecen indicar las investigaciones m&#225;s recientes&#44; el uso de la tomograf&#237;a computarizada de t&#243;rax como m&#233;todo de detecci&#243;n precoz del c&#225;ncer de pulm&#243;n&#44; es probable que se produzca un notable aumento del n&#250;mero de NPS diagnosticados&#46; En tal caso se har&#237;a imprescindible desarrollar t&#233;cnicas que permitan abordar este problema con una &#243;ptima relaci&#243;n riesgo-beneficio&#46; En este trabajo se revisan los fundamentos y los avances que se han producido en el uso de la tomograf&#237;a por emisi&#243;n de positrones como t&#233;cnica de estudio del NPS&#46; Se discuten&#44; asimismo&#44; las causas que explican los posibles falsos positivos y negativos de la prueba&#44; as&#237; como las estrategias dirigidas a incrementar la rentabilidad diagn&#243;stica de este procedimiento&#46;</p>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:1 [
          "bibliografiaReferencia" => array:29 [
            0 => array:3 [
              "identificador" => "bib1"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The solitary pulmonary nodule"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "D Ost"
                            1 => "AM Fein"
                            2 => "SH Feinsilver"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1056/NEJMcp012290"
                      "Revista" => array:6 [
                        "tituloSerie" => "N Engl J Med"
                        "fecha" => "2003"
                        "volumen" => "348"
                        "paginaInicial" => "2535"
                        "paginaFinal" => "2542"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12815140"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib2"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Evaluation of the solitary pulmonary nodule by positron emission tomography imaging"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "T Bury"
                            1 => "A Dowlati"
                            2 => "P Paulus"
                            3 => "JL Corhay"
                            4 => "T Benoit"
                            5 => "JM Kayembe"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur Respir J"
                        "fecha" => "1996"
                        "volumen" => "9"
                        "paginaInicial" => "410"
                        "paginaFinal" => "414"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8729997"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib3"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The probability of malignancy in solitary pulmonary nodules&#46; Application to small radiologically indeterminate nodules"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "SJ Swensen"
                            1 => "MD Silverstein"
                            2 => "DM Ilstrup"
                            3 => "CD Schleck"
                            4 => "ES Edell"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Intern Med"
                        "fecha" => "1997"
                        "volumen" => "157"
                        "paginaInicial" => "849"
                        "paginaFinal" => "855"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9129544"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib4"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Survival of patients with stage I lung cancer detected on CT screening"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "The International Early Lung Cancer Action Program investigators"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1056/NEJMoa060476"
                      "Revista" => array:6 [
                        "tituloSerie" => "N Engl J Med"
                        "fecha" => "2006"
                        "volumen" => "355"
                        "paginaInicial" => "1763"
                        "paginaFinal" => "1771"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17065637"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib5"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Glucose utilization in vivo by human pulmonary neoplasms"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "KB Nolop"
                            1 => "CG Rhodes"
                            2 => "LH Brudin"
                            3 => "RP Beaney"
                            4 => "T Krausz"
                            5 => "T Jones"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Cancer"
                        "fecha" => "1987"
                        "volumen" => "60"
                        "paginaInicial" => "2682"
                        "paginaFinal" => "2689"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3499969"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib6"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Controlled prospective study of positron emission tomography using the glucose analogue 18F-fluorodeoxyglucose in the evaluation of pulmonary nodules"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "HW Pra&#252;er"
                            1 => "WA Weber"
                            2 => "W R&#246;mer"
                            3 => "T Treuman"
                            4 => "SI Ziegler"
                            5 => "M Schwaiger"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1046/j.1365-2168.1998.00915.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "Br J Surg"
                        "fecha" => "1998"
                        "volumen" => "85"
                        "paginaInicial" => "1506"
                        "paginaFinal" => "1511"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9823912"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib7"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Valor del PET-18FDG en el c&#225;ncer de pulm&#243;n"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "JA Richter"
                            1 => "W Torre"
                            2 => "C G&#225;mez"
                            3 => "JM Aramend&#237;a"
                            4 => "A Crespo"
                            5 => "A Nicol&#225;s"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Med Clin &#40;Barc&#41;"
                        "fecha" => "1999"
                        "volumen" => "113"
                        "paginaInicial" => "567"
                        "paginaFinal" => "571"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib8"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The performance of 18-F-fluorodeoxyglucose positron emission tomography in small solitary pulmonary nodules"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "GJ Herder"
                            1 => "RP Golding"
                            2 => "OS Hoekstra"
                            3 => "EF Comans"
                            4 => "GJ Teule"
                            5 => "PE Postmus"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Eur J Nucl Mol Imaging"
                        "fecha" => "2004"
                        "volumen" => "31"
                        "paginaInicial" => "1231"
                        "paginaFinal" => "1236"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib9"
              "etiqueta" => "9"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Exactitud diagn&#243;stica del an&#225;lisis semicuantitativo de la tomograf&#237;a por emisi&#243;n de positrones en lesiones pulmonares radiol&#243;gicamente indeterminadas"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "G Ruiz Hern&#225;ndez"
                            1 => "A Gonz&#225;lez"
                            2 => "R de Juan"
                            3 => "H Verea"
                            4 => "LM Callol"
                            5 => "M Domper"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Rev Esp Med Nucl"
                        "fecha" => "2002"
                        "volumen" => "21"
                        "paginaInicial" => "403"
                        "paginaFinal" => "409"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12425887"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib10"
              "etiqueta" => "10"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Accuracy of positron emission tomography for diagnosis of pulmonary nodules and mass lesions&#46; A meta-analysis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "MK Gould"
                            1 => "CC Maclean"
                            2 => "WG Kuschner"
                            3 => "CE Rydzak"
                            4 => "DK Owens"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "JAMA"
                        "fecha" => "2001"
                        "volumen" => "285"
                        "paginaInicial" => "936"
                        "paginaFinal" => "937"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11180738"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib11"
              "etiqueta" => "11"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Textiloma intrator&#225;cico interpretado como carcinoma broncog&#233;nico&#46; Otro falso positivo de la tomograf&#237;a por emisi&#243;n de positrones"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "C Garc&#237;a de Llanos"
                            1 => "P Cabrera Navarro"
                            2 => "J Freixinet Gilart"
                            3 => "P Rodr&#237;guez Su&#225;rez"
                            4 => "M Hussein Serhald"
                            5 => "T Romero Saavedra"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Bronconeumol"
                        "fecha" => "2007"
                        "volumen" => "43"
                        "paginaInicial" => "292"
                        "paginaFinal" => "294"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17519142"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib12"
              "etiqueta" => "12"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Diagnostic efficacy of PET-FDG imaging in solitary pulmonary nodules&#46; Potential role in evaluation and management"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "NA Dewan"
                            1 => "NC Gupta"
                            2 => "LS Redepenning"
                            3 => "JJ Phalen"
                            4 => "MP Frick"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "1993"
                        "volumen" => "104"
                        "paginaInicial" => "997"
                        "paginaFinal" => "1002"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8404239"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib13"
              "etiqueta" => "13"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Use of a corrected standardized uptake value based on the lesion size on CT permits accurate characterization of lung nodules on FDG-PET"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M Hickeson"
                            1 => "M Yun"
                            2 => "A Matthies"
                            3 => "H Zhuang"
                            4 => "LE Adam"
                            5 => "L Lacorte"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Eur J Nucl Med"
                        "fecha" => "2002"
                        "volumen" => "29"
                        "paginaInicial" => "1639"
                        "paginaFinal" => "1647"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib14"
              "etiqueta" => "14"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Effect of dietary intake before F-18 FDG positron emission tomographic scanning on the evaluation of a solitary pulmonary nodule"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "B Ojha"
                            1 => "SC Bartley"
                            2 => "S Gundlapalli"
                            3 => "JM Mountz"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Nucl Med"
                        "fecha" => "2001"
                        "volumen" => "26"
                        "paginaInicial" => "908"
                        "paginaFinal" => "909"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11595840"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib15"
              "etiqueta" => "15"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The maximum standardized uptake values on integrated FDG-PET&#47;CT is useful in differentiating benign from malignant pulmonary nodules"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "AS Bryant"
                            1 => "RJ Cerfolio"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.athoracsur.2006.03.095"
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Thorac Surg"
                        "fecha" => "2006"
                        "volumen" => "82"
                        "paginaInicial" => "1016"
                        "paginaFinal" => "1020"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16928527"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib16"
              "etiqueta" => "16"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Bronchioalveolar cell carcinoma&#58; radiologic appearance and dilemmas in the assessment of response"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "BS Sabloff"
                            1 => "MT Truong"
                            2 => "II Wistuba"
                            3 => "JJ Erasmus"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.3816/CLC.2004.n.024"
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Lung Cancer"
                        "fecha" => "2004"
                        "volumen" => "6"
                        "paginaInicial" => "108"
                        "paginaFinal" => "112"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15476596"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib17"
              "etiqueta" => "17"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Correlation of glut-1 glucose transporter expression with &#91;18F&#93;FDG uptake in non-small cell lung cancer"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "K Higashi"
                            1 => "Y Ueda"
                            2 => "A Sakurai"
                            3 => "XM Wang"
                            4 => "L Xu"
                            5 => "M Murakami"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur J Nucl Med"
                        "fecha" => "2000"
                        "volumen" => "27"
                        "paginaInicial" => "1778"
                        "paginaFinal" => "1785"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11189940"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib18"
              "etiqueta" => "18"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Fluorine-18-FDG PET imaging is negative in bronchioloalveolar lung carcinoma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "K Higashi"
                            1 => "Y Ueda"
                            2 => "H Seki"
                            3 => "K Yuasa"
                            4 => "M Oguchi"
                            5 => "T Noguchi"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Nucl Med"
                        "fecha" => "1998"
                        "volumen" => "39"
                        "paginaInicial" => "1016"
                        "paginaFinal" => "1020"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9627336"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib19"
              "etiqueta" => "19"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Developments in PET for the detection of endocrine tumors"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "B Eriksson"
                            1 => "H &#214;rlefors"
                            2 => "K Oberg"
                            3 => "A Sundin"
                            4 => "M Bergstr&#246;m"
                            5 => "B L&#229;ngstr&#246;m"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.beem.2004.11.001"
                      "Revista" => array:6 [
                        "tituloSerie" => "Best Pract Res Clin Endocrinol Metab"
                        "fecha" => "2005"
                        "volumen" => "19"
                        "paginaInicial" => "311"
                        "paginaFinal" => "324"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15763703"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib20"
              "etiqueta" => "20"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Evaluation of primary pulmonary carcinoid tumors using FDG-PET"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "JJ Erasmus"
                            1 => "HP McAdams"
                            2 => "EF Patz Jr"
                            3 => "RE Coleman"
                            4 => "V Ahuja"
                            5 => "PC Goodman"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.2214/ajr.170.5.9574618"
                      "Revista" => array:6 [
                        "tituloSerie" => "AJR"
                        "fecha" => "1998"
                        "volumen" => "170"
                        "paginaInicial" => "1369"
                        "paginaFinal" => "1373"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9574618"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bib21"
              "etiqueta" => "21"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Factores pron&#243;sticos en met&#225;stasis pulmonares resecables de carcinoma colorrectal"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "A Mu&#241;oz Llarena"
                            1 => "S Carrera Revilla"
                            2 => "A Gil-Negrete Laborda"
                            3 => "J Pac Ferrer"
                            4 => "R Barcel&#243; Gal&#237;ndez"
                            5 => "G L&#243;pez Vivanco"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Bronconeumol"
                        "fecha" => "2007"
                        "volumen" => "43"
                        "paginaInicial" => "309"
                        "paginaFinal" => "316"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17583640"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            21 => array:3 [
              "identificador" => "bib22"
              "etiqueta" => "22"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Value of whole body FDG-PET in management of lung cancer"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "K Higashi"
                            1 => "I Matsunari"
                            2 => "Y Ueda"
                            3 => "R Ikeda"
                            4 => "J Guo"
                            5 => "M Oguchi"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Nucl Med"
                        "fecha" => "2003"
                        "volumen" => "17"
                        "paginaInicial" => "1"
                        "paginaFinal" => "14"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12691125"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            22 => array:3 [
              "identificador" => "bib23"
              "etiqueta" => "23"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "P-glycoprotein expression is associated with FDG uptake and cell differentiation in patients with untreated lung cancer"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "K Higashi"
                            1 => "Y Ueda"
                            2 => "R Ikeda"
                            3 => "Y Kodama"
                            4 => "J Guo"
                            5 => "I Matsunari"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Nucl Med Commun"
                        "fecha" => "2004"
                        "volumen" => "25"
                        "paginaInicial" => "19"
                        "paginaFinal" => "27"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15061261"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            23 => array:3 [
              "identificador" => "bib24"
              "etiqueta" => "24"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Clinical prediction model to characterize pulmonary nodules&#46; Validation and added value of 18F-fluorodeoxy-glucose positron emission tomography"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "GJ Herder"
                            1 => "H Van Tinteren"
                            2 => "RP Golding"
                            3 => "PJ Kostense"
                            4 => "EF Comans"
                            5 => "EF Smit"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1378/chest.128.4.2490"
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "2005"
                        "volumen" => "128"
                        "paginaInicial" => "2490"
                        "paginaFinal" => "2496"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16236914"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            24 => array:3 [
              "identificador" => "bib25"
              "etiqueta" => "25"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Likelihood of malignancy in a solitary pulmonary nodule&#46; Comparison of Bayesian analysis and results of FDG-PET scan"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "NA Dewan"
                            1 => "CJ Shehan"
                            2 => "SD Reer"
                            3 => "LS Gobar"
                            4 => "WJ Scott"
                            5 => "K Ryschon"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "1997"
                        "volumen" => "112"
                        "paginaInicial" => "416"
                        "paginaFinal" => "422"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9266877"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            25 => array:3 [
              "identificador" => "bib26"
              "etiqueta" => "26"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Dual time point 18F-FDG PET imaging for differentiating malignant from inflammatory processes"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "H Zhuang"
                            1 => "M Pourdehnad"
                            2 => "ES Lambright"
                            3 => "AJ Yamamoto"
                            4 => "M Lanuti"
                            5 => "P Li"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Nucl Med"
                        "fecha" => "2001"
                        "volumen" => "42"
                        "paginaInicial" => "1412"
                        "paginaFinal" => "1417"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11535734"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            26 => array:3 [
              "identificador" => "bib27"
              "etiqueta" => "27"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Reproducibility of common semi-quantitative parameters for evaluating lung cancer glucose metabolism with positron emission tomography using 2-deoxy-2-18F-fluoro-D-glucose"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "Y Nakamoto"
                            1 => "KR Zasadny"
                            2 => "H Minn"
                            3 => "RL Wahl"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Mol Imaging Biol"
                        "fecha" => "2002"
                        "volumen" => "4"
                        "paginaInicial" => "171"
                        "paginaFinal" => "178"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14537140"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0140673600049709"
                          "estado" => "S300"
                          "issn" => "01406736"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            27 => array:3 [
              "identificador" => "bib28"
              "etiqueta" => "28"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Utilidad de la tomograf&#237;a por emisi&#243;n de positrones-tomograf&#237;a computarizada &#40;PET-TC&#41; en neumolog&#237;a"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "A Maldonado"
                            1 => "FJ Gonz&#225;lez-Alenda"
                            2 => "M Alonso"
                            3 => "JM Sierra"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Bronconeumol"
                        "fecha" => "2007"
                        "volumen" => "43"
                        "paginaInicial" => "562"
                        "paginaFinal" => "572"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17939911"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            28 => array:3 [
              "identificador" => "bib29"
              "etiqueta" => "29"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Accuracy of PET&#47;CT in characterization of solitary pulmonary lesions"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "SK Kim"
                            1 => "M Allen-Auerbach"
                            2 => "J Goldin"
                            3 => "BJ Fueger"
                            4 => "M Dahlbom"
                            5 => "M Brown"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Nucl Med"
                        "fecha" => "2007"
                        "volumen" => "48"
                        "paginaInicial" => "214"
                        "paginaFinal" => "220"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17268017"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/15792129/0000004400000009/v1_201305150400/S1579212908600890/v1_201305150400/en/main.assets"
  "Apartado" => null
  "PDF" => "https://static.elsevier.es/multimedia/15792129/0000004400000009/v1_201305150400/S1579212908600890/v1_201305150400/en/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212908600890?idApp=UINPBA00003Z"
]
Share
Journal Information

Statistics

Follow this link to access the full text of the article

Review Article
Positron Emission Tomography for the Study of Solitary Pulmonary Nodules
Iván Márquez Rodasa, Javier de Miguel Díezb,
Corresponding author
jmiguel.hgugm@salud.madrid.org

Correspondencia: Dr J. de Miguel Díez Servicio de Neumología Hospital Universitario Gregorio Marañón Dr. Esquerdo, 46 28007 Madrid, Spain
, José Luis Álvarez-Salac
a Servicio de Oncología Médica, Hospital Universitario Gregorio Marañón, Departamento de Fisiología, Facultad de Medicina, Universidad Autónoma de Madrid, Madrid, Spain
b Servicio de Neumología, Hospital Universitario Gregorio Marañón, Universidad Complutense de Madrid, Madrid, Spain
c Servicio de Neumología, Hospital Clínico San Carlos, Universidad Complutense de Madrid, Madrid, Spain
Read
4508
Times
was read the article
1811
Total PDF
2697
Total HTML
Share statistics
 array:23 [
  "pii" => "S1579212908600890"
  "issn" => "15792129"
  "doi" => "10.1016/S1579-2129(08)60089-0"
  "estado" => "S300"
  "fechaPublicacion" => "2008-01-01"
  "aid" => "60089"
  "copyright" => "Sociedad Espa&#241;ola de Neumolog&#237;a y Cirug&#237;a Tor&#225;cica &#40;SEPAR&#41;"
  "copyrightAnyo" => "2008"
  "documento" => "article"
  "crossmark" => 0
  "subdocumento" => "rev"
  "cita" => "Arch Bronconeumol. 2008;44:493-8"
  "abierto" => array:3 [
    "ES" => false
    "ES2" => false
    "LATM" => false
  ]
  "gratuito" => false
  "lecturas" => array:2 [
    "total" => 2622
    "formatos" => array:3 [
      "EPUB" => 108
      "HTML" => 1926
      "PDF" => 588
    ]
  ]
  "itemSiguiente" => array:18 [
    "pii" => "S1579212908600907"
    "issn" => "15792129"
    "doi" => "10.1016/S1579-2129(08)60090-7"
    "estado" => "S300"
    "fechaPublicacion" => "2008-01-01"
    "aid" => "60090"
    "copyright" => "Sociedad Espa&#241;ola de Neumolog&#237;a y Cirug&#237;a Tor&#225;cica &#40;SEPAR&#41;"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "sco"
    "cita" => "Arch Bronconeumol. 2008;44:499-503"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 6053
      "formatos" => array:3 [
        "EPUB" => 117
        "HTML" => 5065
        "PDF" => 871
      ]
    ]
    "en" => array:10 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Case Reports</span>"
      "titulo" => "Desquamative Interstitial Pneumonia and Respiratory Bronchiolitis-Associated Interstitial Lung Disease&#58; Data From the Spanish Patient Registry"
      "tienePdf" => "en"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "499"
          "paginaFinal" => "503"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Adolfo Baloira, Antoni Xaubet, Eulogio Rodr&#237;guez Becerra, Ana Dolores Romero, &#193;lvaro Casanova, Julio Ancochea"
          "autores" => array:6 [
            0 => array:2 [
              "nombre" => "Adolfo"
              "apellidos" => "Baloira"
            ]
            1 => array:2 [
              "nombre" => "Antoni"
              "apellidos" => "Xaubet"
            ]
            2 => array:2 [
              "nombre" => "Eulogio"
              "apellidos" => "Rodr&#237;guez Becerra"
            ]
            3 => array:2 [
              "nombre" => "Ana Dolores"
              "apellidos" => "Romero"
            ]
            4 => array:2 [
              "nombre" => "&#193;lvaro"
              "apellidos" => "Casanova"
            ]
            5 => array:2 [
              "nombre" => "Julio"
              "apellidos" => "Ancochea"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212908600907?idApp=UINPBA00003Z"
    "url" => "/15792129/0000004400000009/v1_201305150400/S1579212908600907/v1_201305150400/en/main.assets"
  ]
  "itemAnterior" => array:18 [
    "pii" => "S1579212908600889"
    "issn" => "15792129"
    "doi" => "10.1016/S1579-2129(08)60088-9"
    "estado" => "S300"
    "fechaPublicacion" => "2008-01-01"
    "aid" => "60088"
    "copyright" => "Sociedad Espa&#241;ola de Neumolog&#237;a y Cirug&#237;a Tor&#225;cica &#40;SEPAR&#41;"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Arch Bronconeumol. 2008;44:489-92"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 2150
      "formatos" => array:3 [
        "EPUB" => 101
        "HTML" => 1403
        "PDF" => 646
      ]
    ]
    "en" => array:8 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Special Article</span>"
      "titulo" => "CIBER of Respiratory Diseases &#40;CibeRes&#41;"
      "tienePdf" => "en"
      "tieneTextoCompleto" => 0
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "489"
          "paginaFinal" => "492"
        ]
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "&#192;lvar Agust&#237;, Francisco Pozo, Paloma Vaquer"
          "autores" => array:3 [
            0 => array:2 [
              "nombre" => "&#192;lvar"
              "apellidos" => "Agust&#237;"
            ]
            1 => array:2 [
              "nombre" => "Francisco"
              "apellidos" => "Pozo"
            ]
            2 => array:2 [
              "nombre" => "Paloma"
              "apellidos" => "Vaquer"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212908600889?idApp=UINPBA00003Z"
    "url" => "/15792129/0000004400000009/v1_201305150400/S1579212908600889/v1_201305150400/en/main.assets"
  ]
  "en" => array:14 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Review Article</span>"
    "titulo" => "Positron Emission Tomography for the Study of Solitary Pulmonary Nodules"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "493"
        "paginaFinal" => "498"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "Iv&#225;n M&#225;rquez Rodas, Javier de Miguel D&#237;ez, Jos&#233; Luis &#193;lvarez-Sala"
        "autores" => array:3 [
          0 => array:3 [
            "nombre" => "Iv&#225;n"
            "apellidos" => "M&#225;rquez Rodas"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff1"
              ]
            ]
          ]
          1 => array:4 [
            "nombre" => "Javier"
            "apellidos" => "de Miguel D&#237;ez"
            "email" => array:1 [
              0 => "jmiguel&#46;hgugm&#64;salud&#46;madrid&#46;org"
            ]
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff2"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor1"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "Jos&#233; Luis"
            "apellidos" => "&#193;lvarez-Sala"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">c</span>"
                "identificador" => "aff3"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:3 [
          0 => array:3 [
            "entidad" => "Servicio de Oncolog&#237;a M&#233;dica&#44; Hospital Universitario Gregorio Mara&#241;&#243;n&#44; Departamento de Fisiolog&#237;a&#44; Facultad de Medicina&#44; Universidad Aut&#243;noma de Madrid&#44; Madrid&#44; Spain"
            "etiqueta" => "<span class="elsevierStyleSup">a</span>"
            "identificador" => "aff1"
          ]
          1 => array:3 [
            "entidad" => "Servicio de Neumolog&#237;a&#44; Hospital Universitario Gregorio Mara&#241;&#243;n&#44; Universidad Complutense de Madrid&#44; Madrid&#44; Spain"
            "etiqueta" => "<span class="elsevierStyleSup">b</span>"
            "identificador" => "aff2"
          ]
          2 => array:3 [
            "entidad" => "Servicio de Neumolog&#237;a&#44; Hospital Cl&#237;nico San Carlos&#44; Universidad Complutense de Madrid&#44; Madrid&#44; Spain"
            "etiqueta" => "<span class="elsevierStyleSup">c</span>"
            "identificador" => "aff3"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor1"
            "etiqueta" => "&#42;"
            "correspondencia" => "Correspondencia&#58; Dr J&#46; de Miguel D&#237;ez Servicio de Neumolog&#237;a Hospital Universitario Gregorio Mara&#241;&#243;n Dr&#46; Esquerdo&#44; 46 28007 Madrid&#44; Spain"
          ]
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2007-10-22"
    "fechaAceptado" => "2007-11-07"
    "PalabrasClave" => array:2 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Key words"
          "identificador" => "xpalclavsec155401"
          "palabras" => array:3 [
            0 => "Solitary pulmonary nodule"
            1 => "Positron emission tomography"
            2 => "Diagnostic yield"
          ]
        ]
      ]
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec155402"
          "palabras" => array:3 [
            0 => "N&#243;dulo pulmonar solitario"
            1 => "Tomograf&#237;a por emisi&#243;n de positrones"
            2 => "Rentabilidad diagn&#243;stica"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "en" => array:1 [
        "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">Solitary pulmonary nodules are a major clinical challenge for all doctors involved in their study&#46; The aim is always to avoid missing malignant lesions but also to avoid performing unnecessary diagnostic tests&#46; The most recent research suggests that in the near future chest computed tomography will become even more widely used for the early detection of lung cancer&#46; If this occurs&#44; there is likely to be a marked increase in the number of solitary pulmonary nodules detected&#44; making it essential to develop techniques that enable us to manage this problem with an optimal risk-benefit ratio&#46; We review the underlying principles of positron emission tomography and the advances that have been made in its use for the study of solitary pulmonary nodules&#46; In addition&#44; we discuss the possible causes of false positives and negatives in this technique and the strategies aimed at increasing diagnostic yield&#46;</p>"
      ]
      "es" => array:1 [
        "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">El n&#243;dulo pulmonar solitario &#40;NPS&#41; es un reto cl&#237;nico importante para todo m&#233;dico implicado en su estudio&#46; El objetivo se cifra siempre en impedir que una lesi&#243;n maligna pase inadvertida&#44; pero tambi&#233;n en evitar que se realicen pruebas diagn&#243;sticas innecesarias&#46; Si en el futuro inmediato se generaliza todav&#237;a m&#225;s&#44; como parecen indicar las investigaciones m&#225;s recientes&#44; el uso de la tomograf&#237;a computarizada de t&#243;rax como m&#233;todo de detecci&#243;n precoz del c&#225;ncer de pulm&#243;n&#44; es probable que se produzca un notable aumento del n&#250;mero de NPS diagnosticados&#46; En tal caso se har&#237;a imprescindible desarrollar t&#233;cnicas que permitan abordar este problema con una &#243;ptima relaci&#243;n riesgo-beneficio&#46; En este trabajo se revisan los fundamentos y los avances que se han producido en el uso de la tomograf&#237;a por emisi&#243;n de positrones como t&#233;cnica de estudio del NPS&#46; Se discuten&#44; asimismo&#44; las causas que explican los posibles falsos positivos y negativos de la prueba&#44; as&#237; como las estrategias dirigidas a incrementar la rentabilidad diagn&#243;stica de este procedimiento&#46;</p>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:1 [
          "bibliografiaReferencia" => array:29 [
            0 => array:3 [
              "identificador" => "bib1"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The solitary pulmonary nodule"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "D Ost"
                            1 => "AM Fein"
                            2 => "SH Feinsilver"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1056/NEJMcp012290"
                      "Revista" => array:6 [
                        "tituloSerie" => "N Engl J Med"
                        "fecha" => "2003"
                        "volumen" => "348"
                        "paginaInicial" => "2535"
                        "paginaFinal" => "2542"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12815140"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib2"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Evaluation of the solitary pulmonary nodule by positron emission tomography imaging"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "T Bury"
                            1 => "A Dowlati"
                            2 => "P Paulus"
                            3 => "JL Corhay"
                            4 => "T Benoit"
                            5 => "JM Kayembe"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur Respir J"
                        "fecha" => "1996"
                        "volumen" => "9"
                        "paginaInicial" => "410"
                        "paginaFinal" => "414"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8729997"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib3"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The probability of malignancy in solitary pulmonary nodules&#46; Application to small radiologically indeterminate nodules"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "SJ Swensen"
                            1 => "MD Silverstein"
                            2 => "DM Ilstrup"
                            3 => "CD Schleck"
                            4 => "ES Edell"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Intern Med"
                        "fecha" => "1997"
                        "volumen" => "157"
                        "paginaInicial" => "849"
                        "paginaFinal" => "855"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9129544"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib4"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Survival of patients with stage I lung cancer detected on CT screening"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "The International Early Lung Cancer Action Program investigators"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1056/NEJMoa060476"
                      "Revista" => array:6 [
                        "tituloSerie" => "N Engl J Med"
                        "fecha" => "2006"
                        "volumen" => "355"
                        "paginaInicial" => "1763"
                        "paginaFinal" => "1771"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17065637"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib5"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Glucose utilization in vivo by human pulmonary neoplasms"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "KB Nolop"
                            1 => "CG Rhodes"
                            2 => "LH Brudin"
                            3 => "RP Beaney"
                            4 => "T Krausz"
                            5 => "T Jones"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Cancer"
                        "fecha" => "1987"
                        "volumen" => "60"
                        "paginaInicial" => "2682"
                        "paginaFinal" => "2689"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3499969"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib6"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Controlled prospective study of positron emission tomography using the glucose analogue 18F-fluorodeoxyglucose in the evaluation of pulmonary nodules"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "HW Pra&#252;er"
                            1 => "WA Weber"
                            2 => "W R&#246;mer"
                            3 => "T Treuman"
                            4 => "SI Ziegler"
                            5 => "M Schwaiger"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1046/j.1365-2168.1998.00915.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "Br J Surg"
                        "fecha" => "1998"
                        "volumen" => "85"
                        "paginaInicial" => "1506"
                        "paginaFinal" => "1511"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9823912"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib7"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Valor del PET-18FDG en el c&#225;ncer de pulm&#243;n"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "JA Richter"
                            1 => "W Torre"
                            2 => "C G&#225;mez"
                            3 => "JM Aramend&#237;a"
                            4 => "A Crespo"
                            5 => "A Nicol&#225;s"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Med Clin &#40;Barc&#41;"
                        "fecha" => "1999"
                        "volumen" => "113"
                        "paginaInicial" => "567"
                        "paginaFinal" => "571"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib8"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The performance of 18-F-fluorodeoxyglucose positron emission tomography in small solitary pulmonary nodules"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "GJ Herder"
                            1 => "RP Golding"
                            2 => "OS Hoekstra"
                            3 => "EF Comans"
                            4 => "GJ Teule"
                            5 => "PE Postmus"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Eur J Nucl Mol Imaging"
                        "fecha" => "2004"
                        "volumen" => "31"
                        "paginaInicial" => "1231"
                        "paginaFinal" => "1236"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib9"
              "etiqueta" => "9"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Exactitud diagn&#243;stica del an&#225;lisis semicuantitativo de la tomograf&#237;a por emisi&#243;n de positrones en lesiones pulmonares radiol&#243;gicamente indeterminadas"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "G Ruiz Hern&#225;ndez"
                            1 => "A Gonz&#225;lez"
                            2 => "R de Juan"
                            3 => "H Verea"
                            4 => "LM Callol"
                            5 => "M Domper"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Rev Esp Med Nucl"
                        "fecha" => "2002"
                        "volumen" => "21"
                        "paginaInicial" => "403"
                        "paginaFinal" => "409"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12425887"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib10"
              "etiqueta" => "10"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Accuracy of positron emission tomography for diagnosis of pulmonary nodules and mass lesions&#46; A meta-analysis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "MK Gould"
                            1 => "CC Maclean"
                            2 => "WG Kuschner"
                            3 => "CE Rydzak"
                            4 => "DK Owens"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "JAMA"
                        "fecha" => "2001"
                        "volumen" => "285"
                        "paginaInicial" => "936"
                        "paginaFinal" => "937"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11180738"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib11"
              "etiqueta" => "11"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Textiloma intrator&#225;cico interpretado como carcinoma broncog&#233;nico&#46; Otro falso positivo de la tomograf&#237;a por emisi&#243;n de positrones"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "C Garc&#237;a de Llanos"
                            1 => "P Cabrera Navarro"
                            2 => "J Freixinet Gilart"
                            3 => "P Rodr&#237;guez Su&#225;rez"
                            4 => "M Hussein Serhald"
                            5 => "T Romero Saavedra"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Bronconeumol"
                        "fecha" => "2007"
                        "volumen" => "43"
                        "paginaInicial" => "292"
                        "paginaFinal" => "294"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17519142"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib12"
              "etiqueta" => "12"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Diagnostic efficacy of PET-FDG imaging in solitary pulmonary nodules&#46; Potential role in evaluation and management"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "NA Dewan"
                            1 => "NC Gupta"
                            2 => "LS Redepenning"
                            3 => "JJ Phalen"
                            4 => "MP Frick"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "1993"
                        "volumen" => "104"
                        "paginaInicial" => "997"
                        "paginaFinal" => "1002"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8404239"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib13"
              "etiqueta" => "13"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Use of a corrected standardized uptake value based on the lesion size on CT permits accurate characterization of lung nodules on FDG-PET"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M Hickeson"
                            1 => "M Yun"
                            2 => "A Matthies"
                            3 => "H Zhuang"
                            4 => "LE Adam"
                            5 => "L Lacorte"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Eur J Nucl Med"
                        "fecha" => "2002"
                        "volumen" => "29"
                        "paginaInicial" => "1639"
                        "paginaFinal" => "1647"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib14"
              "etiqueta" => "14"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Effect of dietary intake before F-18 FDG positron emission tomographic scanning on the evaluation of a solitary pulmonary nodule"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "B Ojha"
                            1 => "SC Bartley"
                            2 => "S Gundlapalli"
                            3 => "JM Mountz"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Nucl Med"
                        "fecha" => "2001"
                        "volumen" => "26"
                        "paginaInicial" => "908"
                        "paginaFinal" => "909"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11595840"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib15"
              "etiqueta" => "15"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The maximum standardized uptake values on integrated FDG-PET&#47;CT is useful in differentiating benign from malignant pulmonary nodules"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "AS Bryant"
                            1 => "RJ Cerfolio"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.athoracsur.2006.03.095"
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Thorac Surg"
                        "fecha" => "2006"
                        "volumen" => "82"
                        "paginaInicial" => "1016"
                        "paginaFinal" => "1020"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16928527"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib16"
              "etiqueta" => "16"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Bronchioalveolar cell carcinoma&#58; radiologic appearance and dilemmas in the assessment of response"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "BS Sabloff"
                            1 => "MT Truong"
                            2 => "II Wistuba"
                            3 => "JJ Erasmus"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.3816/CLC.2004.n.024"
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Lung Cancer"
                        "fecha" => "2004"
                        "volumen" => "6"
                        "paginaInicial" => "108"
                        "paginaFinal" => "112"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15476596"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib17"
              "etiqueta" => "17"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Correlation of glut-1 glucose transporter expression with &#91;18F&#93;FDG uptake in non-small cell lung cancer"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "K Higashi"
                            1 => "Y Ueda"
                            2 => "A Sakurai"
                            3 => "XM Wang"
                            4 => "L Xu"
                            5 => "M Murakami"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur J Nucl Med"
                        "fecha" => "2000"
                        "volumen" => "27"
                        "paginaInicial" => "1778"
                        "paginaFinal" => "1785"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11189940"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib18"
              "etiqueta" => "18"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Fluorine-18-FDG PET imaging is negative in bronchioloalveolar lung carcinoma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "K Higashi"
                            1 => "Y Ueda"
                            2 => "H Seki"
                            3 => "K Yuasa"
                            4 => "M Oguchi"
                            5 => "T Noguchi"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Nucl Med"
                        "fecha" => "1998"
                        "volumen" => "39"
                        "paginaInicial" => "1016"
                        "paginaFinal" => "1020"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9627336"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib19"
              "etiqueta" => "19"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Developments in PET for the detection of endocrine tumors"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "B Eriksson"
                            1 => "H &#214;rlefors"
                            2 => "K Oberg"
                            3 => "A Sundin"
                            4 => "M Bergstr&#246;m"
                            5 => "B L&#229;ngstr&#246;m"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.beem.2004.11.001"
                      "Revista" => array:6 [
                        "tituloSerie" => "Best Pract Res Clin Endocrinol Metab"
                        "fecha" => "2005"
                        "volumen" => "19"
                        "paginaInicial" => "311"
                        "paginaFinal" => "324"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15763703"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib20"
              "etiqueta" => "20"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Evaluation of primary pulmonary carcinoid tumors using FDG-PET"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "JJ Erasmus"
                            1 => "HP McAdams"
                            2 => "EF Patz Jr"
                            3 => "RE Coleman"
                            4 => "V Ahuja"
                            5 => "PC Goodman"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.2214/ajr.170.5.9574618"
                      "Revista" => array:6 [
                        "tituloSerie" => "AJR"
                        "fecha" => "1998"
                        "volumen" => "170"
                        "paginaInicial" => "1369"
                        "paginaFinal" => "1373"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9574618"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bib21"
              "etiqueta" => "21"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Factores pron&#243;sticos en met&#225;stasis pulmonares resecables de carcinoma colorrectal"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "A Mu&#241;oz Llarena"
                            1 => "S Carrera Revilla"
                            2 => "A Gil-Negrete Laborda"
                            3 => "J Pac Ferrer"
                            4 => "R Barcel&#243; Gal&#237;ndez"
                            5 => "G L&#243;pez Vivanco"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Bronconeumol"
                        "fecha" => "2007"
                        "volumen" => "43"
                        "paginaInicial" => "309"
                        "paginaFinal" => "316"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17583640"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            21 => array:3 [
              "identificador" => "bib22"
              "etiqueta" => "22"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Value of whole body FDG-PET in management of lung cancer"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "K Higashi"
                            1 => "I Matsunari"
                            2 => "Y Ueda"
                            3 => "R Ikeda"
                            4 => "J Guo"
                            5 => "M Oguchi"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Nucl Med"
                        "fecha" => "2003"
                        "volumen" => "17"
                        "paginaInicial" => "1"
                        "paginaFinal" => "14"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12691125"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            22 => array:3 [
              "identificador" => "bib23"
              "etiqueta" => "23"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "P-glycoprotein expression is associated with FDG uptake and cell differentiation in patients with untreated lung cancer"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "K Higashi"
                            1 => "Y Ueda"
                            2 => "R Ikeda"
                            3 => "Y Kodama"
                            4 => "J Guo"
                            5 => "I Matsunari"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Nucl Med Commun"
                        "fecha" => "2004"
                        "volumen" => "25"
                        "paginaInicial" => "19"
                        "paginaFinal" => "27"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15061261"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            23 => array:3 [
              "identificador" => "bib24"
              "etiqueta" => "24"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Clinical prediction model to characterize pulmonary nodules&#46; Validation and added value of 18F-fluorodeoxy-glucose positron emission tomography"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "GJ Herder"
                            1 => "H Van Tinteren"
                            2 => "RP Golding"
                            3 => "PJ Kostense"
                            4 => "EF Comans"
                            5 => "EF Smit"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1378/chest.128.4.2490"
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "2005"
                        "volumen" => "128"
                        "paginaInicial" => "2490"
                        "paginaFinal" => "2496"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16236914"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            24 => array:3 [
              "identificador" => "bib25"
              "etiqueta" => "25"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Likelihood of malignancy in a solitary pulmonary nodule&#46; Comparison of Bayesian analysis and results of FDG-PET scan"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "NA Dewan"
                            1 => "CJ Shehan"
                            2 => "SD Reer"
                            3 => "LS Gobar"
                            4 => "WJ Scott"
                            5 => "K Ryschon"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "1997"
                        "volumen" => "112"
                        "paginaInicial" => "416"
                        "paginaFinal" => "422"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9266877"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            25 => array:3 [
              "identificador" => "bib26"
              "etiqueta" => "26"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Dual time point 18F-FDG PET imaging for differentiating malignant from inflammatory processes"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "H Zhuang"
                            1 => "M Pourdehnad"
                            2 => "ES Lambright"
                            3 => "AJ Yamamoto"
                            4 => "M Lanuti"
                            5 => "P Li"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Nucl Med"
                        "fecha" => "2001"
                        "volumen" => "42"
                        "paginaInicial" => "1412"
                        "paginaFinal" => "1417"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11535734"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            26 => array:3 [
              "identificador" => "bib27"
              "etiqueta" => "27"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Reproducibility of common semi-quantitative parameters for evaluating lung cancer glucose metabolism with positron emission tomography using 2-deoxy-2-18F-fluoro-D-glucose"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "Y Nakamoto"
                            1 => "KR Zasadny"
                            2 => "H Minn"
                            3 => "RL Wahl"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Mol Imaging Biol"
                        "fecha" => "2002"
                        "volumen" => "4"
                        "paginaInicial" => "171"
                        "paginaFinal" => "178"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14537140"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0140673600049709"
                          "estado" => "S300"
                          "issn" => "01406736"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            27 => array:3 [
              "identificador" => "bib28"
              "etiqueta" => "28"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Utilidad de la tomograf&#237;a por emisi&#243;n de positrones-tomograf&#237;a computarizada &#40;PET-TC&#41; en neumolog&#237;a"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "A Maldonado"
                            1 => "FJ Gonz&#225;lez-Alenda"
                            2 => "M Alonso"
                            3 => "JM Sierra"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Bronconeumol"
                        "fecha" => "2007"
                        "volumen" => "43"
                        "paginaInicial" => "562"
                        "paginaFinal" => "572"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17939911"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            28 => array:3 [
              "identificador" => "bib29"
              "etiqueta" => "29"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Accuracy of PET&#47;CT in characterization of solitary pulmonary lesions"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "SK Kim"
                            1 => "M Allen-Auerbach"
                            2 => "J Goldin"
                            3 => "BJ Fueger"
                            4 => "M Dahlbom"
                            5 => "M Brown"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Nucl Med"
                        "fecha" => "2007"
                        "volumen" => "48"
                        "paginaInicial" => "214"
                        "paginaFinal" => "220"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17268017"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/15792129/0000004400000009/v1_201305150400/S1579212908600890/v1_201305150400/en/main.assets"
  "Apartado" => null
  "PDF" => "https://static.elsevier.es/multimedia/15792129/0000004400000009/v1_201305150400/S1579212908600890/v1_201305150400/en/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212908600890?idApp=UINPBA00003Z"
]
Article information
ISSN: 15792129
Original language: English
The statistics are updated each day
Year/Month Html Pdf Total
2024 November 6 3 9
2024 October 29 15 44
2024 September 24 15 39
2024 August 40 31 71
2024 July 23 26 49
2024 June 40 32 72
2024 May 40 35 75
2024 April 17 26 43
2024 March 21 15 36
2024 February 15 16 31
2023 March 3 2 5
2023 February 22 20 42
2023 January 16 25 41
2022 December 22 30 52
2022 November 19 26 45
2022 October 18 34 52
2022 September 20 21 41
2022 August 16 31 47
2022 July 19 41 60
2022 June 16 33 49
2022 May 16 22 38
2022 April 15 32 47
2022 March 14 34 48
2022 February 14 34 48
2022 January 10 30 40
2021 December 13 50 63
2021 November 18 54 72
2021 October 21 56 77
2021 September 18 63 81
2021 August 15 29 44
2021 July 7 32 39
2021 June 12 35 47
2021 May 10 27 37
2021 April 20 69 89
2021 March 13 21 34
2021 February 13 20 33
2021 January 9 14 23
2020 December 8 11 19
2020 November 5 15 20
2020 October 5 13 18
2020 September 4 3 7
2020 August 9 13 22
2020 July 12 17 29
2020 June 6 4 10
2020 May 14 12 26
2020 April 20 18 38
2020 March 11 13 24
2020 February 22 15 37
2020 January 14 16 30
2019 December 10 15 25
2019 November 11 12 23
2019 October 6 7 13
2019 September 6 7 13
2019 August 12 13 25
2019 July 9 26 35
2019 June 7 7 14
2019 May 10 9 19
2019 April 14 37 51
2019 March 11 11 22
2019 February 7 8 15
2019 January 5 7 12
2018 December 10 9 19
2018 November 16 12 28
2018 October 13 14 27
2018 September 11 5 16
2018 May 2 0 2
2018 April 8 8 16
2018 March 5 5 10
2018 February 2 5 7
2018 January 3 5 8
2017 December 3 4 7
2017 November 2 4 6
2017 October 5 6 11
2017 September 8 8 16
2017 August 9 12 21
2017 July 6 5 11
2017 June 7 12 19
2017 May 5 3 8
2017 April 6 5 11
2017 March 9 4 13
2017 February 4 6 10
2017 January 4 4 8
2016 December 4 6 10
2016 November 4 4 8
2016 October 12 11 23
2016 September 6 11 17
2016 August 8 4 12
2016 July 7 3 10
2016 March 2 0 2
2016 February 1 0 1
2015 December 2 0 2
2015 October 42 12 54
2015 September 63 8 71
2015 August 58 11 69
2015 July 88 6 94
2015 June 43 2 45
2015 May 53 3 56
2015 April 50 9 59
2015 March 48 7 55
2015 February 37 0 37
2015 January 37 5 42
2014 December 43 4 47
2014 November 50 4 54
2014 October 54 6 60
2014 September 38 4 42
2014 August 59 9 68
2014 July 39 7 46
2014 June 76 8 84
2014 May 51 10 61
2014 April 65 4 69
2014 March 77 9 86
2014 February 77 9 86
2014 January 45 9 54
2013 December 52 8 60
2013 November 46 7 53
2013 October 51 9 60
2013 September 59 10 69
2013 August 48 5 53
2013 July 53 17 70
2013 June 42 10 52
2013 May 43 9 52
2013 April 18 5 23
2013 March 6 2 8
Show all

Follow this link to access the full text of the article

Archivos de Bronconeumología

Are you a health professional able to prescribe or dispense drugs?