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Clinical and Functional Characteristics of Patients Prior to Lung Transplantation: Report of Experience at the Clínica Puerta de Hierro
Rosalía Laporta
, Piedad Ussetti, Gema Mora, Cristina López, David Gómez, Alicia de Pablo, M. Teresa Lázaro, M. Cruz Carreño, M. José Ferreiro
Corresponding author
Servicio de Neumología, Clínica Puerta de Hierro, Madrid, Spain
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Moro, Luis Almenar, Estrella Fernández-Fabrellas, Silvia Ponce, Rafael Blanquer, Antonio Salvador" "autores" => array:6 [ 0 => array:2 [ "nombre" => "José A." "apellidos" => "Moro" ] 1 => array:2 [ "nombre" => "Luis" "apellidos" => "Almenar" ] 2 => array:2 [ "nombre" => "Estrella" "apellidos" => "Fernández-Fabrellas" ] 3 => array:2 [ "nombre" => "Silvia" "apellidos" => "Ponce" ] 4 => array:2 [ "nombre" => "Rafael" "apellidos" => "Blanquer" ] 5 => array:2 [ "nombre" => "Antonio" "apellidos" => "Salvador" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212908600749?idApp=UINPBA00003Z" "url" => "/15792129/0000004400000008/v1_201305150357/S1579212908600749/v1_201305150357/en/main.assets" ] "en" => array:14 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Original Articles</span>" "titulo" => "Clinical and Functional Characteristics of Patients Prior to Lung Transplantation: Report of Experience at the Clínica Puerta de Hierro" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "424" "paginaFinal" => "427" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Rosalía Laporta, Piedad Ussetti, Gema Mora, Cristina López, David Gómez, Alicia de Pablo, M. Teresa Lázaro, M. Cruz Carreño, M. José Ferreiro" "autores" => array:9 [ 0 => array:4 [ "nombre" => "Rosalía" "apellidos" => "Laporta" "email" => array:1 [ 0 => "roslaporta@terra.es" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor1" ] ] ] 1 => array:2 [ "nombre" => "Piedad" "apellidos" => "Ussetti" ] 2 => array:2 [ "nombre" => "Gema" "apellidos" => "Mora" ] 3 => array:2 [ "nombre" => "Cristina" "apellidos" => "López" ] 4 => array:2 [ "nombre" => "David" "apellidos" => "Gómez" ] 5 => array:2 [ "nombre" => "Alicia" "apellidos" => "de Pablo" ] 6 => array:2 [ "nombre" => "M." "apellidos" => "Teresa Lázaro" ] 7 => array:2 [ "nombre" => "M." "apellidos" => "Cruz Carreño" ] 8 => array:2 [ "nombre" => "M." "apellidos" => "José Ferreiro" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Servicio de Neumología, Clínica Puerta de Hierro, Madrid, Spain" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "*" "correspondencia" => "Correspondence: Dr R. Laporta Luna, 1 (2º, 2ª) 28220 Majadahonda, Madrid, Spain" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2007-06-25" "fechaAceptado" => "2007-12-12" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec155348" "palabras" => array:4 [ 0 => "Lung transplantation" 1 => "Lung disease" 2 => "Spirometry" 3 => "Selection of patients" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec155349" "palabras" => array:4 [ 0 => "Trasplante pulmonar" 1 => "Enfermedad pulmonar" 2 => "Espirometría" 3 => "Selección de pacientes" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">The time at which lung transplantation is indicated is determined by clinical and functional criteria that vary according to the particular disease. The aim of our study was to present the criteria according to which patients were placed on waiting lists for lung transplantation in our hospital.</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p class="elsevierStyleSimplePara elsevierViewall">We analyzed retrospectively the clinical characteristics, lung function, heart function, and 6-minute walk test results of patients who had received a lung transplant in our hospital from January 2002 through September 2005.</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">During the study period 100 lung transplants were performed. The mean age of the patients was 45 years (range, 15–67 years) and 57% were men. The diseases that most often led to a lung transplant were chronic obstructive pulmonary disease (COPD) (35%), pulmonary fibrosis (29%), and bronchiectasis (21%). Lung function values differed by disease: mean (SD) forced expiratory volume in 1 second (FEV<span class="elsevierStyleInf">1</span>) was 20% (11%) and forced vital capacity (FVC) was 37% (15%) in patients with COPD; FEV<span class="elsevierStyleInf">1</span> was 41% (15%) and FVC, 40% (17%) in patients with pulmonary fibrosis; and FEV<span class="elsevierStyleInf">1</span> was 23% (7%) and FVC, 37% (10%) in patients with bronchiectasis.</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">The patients who received lung transplants in our hospital were in advanced phases of their disease and met the inclusion criteria accepted by the various medical associations when they were placed on the waiting list.</p>" ] "es" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">El momento para indicar un trasplante pulmonar está definido por criterios clínicos y funcionales diferentes para cada enfermedad. El objetivo de este estudio es presentar cuáles fueron los criterios por los que en nuestro hospital se incluyó a los pacientes en lista de espera de trasplante pulmonar.</p> <span class="elsevierStyleSectionTitle">Pacientes y métodos</span><p class="elsevierStyleSimplePara elsevierViewall">Se ha realizado un análisis retrospectivo de las características clínicas, la función respiratoria, la prueba de la marcha de 6 minutos y el estudio cardiológico de los pacientes que recibieron un trasplante pulmonar entre enero de 2002 y septiembre de 2005.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">En el período estudiado se realizaron 100 trasplantes pulmonares. La edad media de los pacientes era de 45 años (rango: 15–67) y el 57% eran varones. Las enfermedades que con mayor frecuencia motivaron el trasplante pulmonar fueron la enfermedad pulmonar obstructiva crónica (EPOC, 35%), la fibrosis pulmonar (29%) y las bronquiectasias (BQ) (21%). La media ± desviación estándar de la función pulmonar osciló entre el 20 ± 11% del volumen espiratorio forzado en el primer segundo (FEV<span class="elsevierStyleInf">1</span>) y el 37 ± 15% de la capacidad vital forzada (FVC) en la EPOC; del 41 ± 15% del FEV<span class="elsevierStyleInf">1</span> y el 40 ± 17% de la FVC en la fibrosis pulmonar, y del 23 ± 7% del FEV<span class="elsevierStyleInf">1</span> y el 37 ± 10% de la FVC en las BQ.</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">Los pacientes que recibieron un trasplante pulmonar en nuestro centro se encontraban en fases muy evolucionadas de su enfermedad y cumplían los criterios de inclusión admitidos por las diferentes sociedades médicas cuando se les incluyó en lista de espera.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:23 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Trasplante pulmonar en España" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "A Salvatierra Velázquez" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Arch Bronconeumol" "fecha" => "2004" "volumen" => "40" "numero" => "Suppl 6" "paginaInicial" => "41" "paginaFinal" => "48" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16137466" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Actualización del trasplante pulmonar en España" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "JM Borro" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Bronconeumol" "fecha" => "2005" "volumen" => "41" "paginaInicial" => "457" "paginaFinal" => "467" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16117951" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib3" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "International guidelines for the selection of lung transplant candidates" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "JB Orens" 1 => "M Estenne" 2 => "S Arcasoy" 3 => "JV Conte" 4 => "P Corris" 5 => "JJ Egan" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.healun.2006.03.011" "Revista" => array:6 [ "tituloSerie" => "J Heart Lung Transplant" "fecha" => "2006" "volumen" => "25" "paginaInicial" => "745" "paginaFinal" => "755" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16818116" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib4" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Normativa SEPAR. 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| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 2 | 3 | 5 |
| 2024 October | 29 | 13 | 42 |
| 2024 September | 26 | 16 | 42 |
| 2024 August | 47 | 32 | 79 |
| 2024 July | 23 | 19 | 42 |
| 2024 June | 35 | 22 | 57 |
| 2024 May | 29 | 26 | 55 |
| 2024 April | 21 | 25 | 46 |
| 2024 March | 22 | 18 | 40 |
| 2024 February | 16 | 17 | 33 |
| 2023 March | 2 | 3 | 5 |
| 2023 February | 22 | 13 | 35 |
| 2023 January | 16 | 37 | 53 |
| 2022 December | 16 | 39 | 55 |
| 2022 November | 27 | 24 | 51 |
| 2022 October | 34 | 28 | 62 |
| 2022 September | 17 | 29 | 46 |
| 2022 August | 25 | 38 | 63 |
| 2022 July | 16 | 43 | 59 |
| 2022 June | 25 | 29 | 54 |
| 2022 May | 43 | 36 | 79 |
| 2022 April | 27 | 21 | 48 |
| 2022 March | 23 | 34 | 57 |
| 2022 February | 19 | 29 | 48 |
| 2022 January | 16 | 28 | 44 |
| 2021 December | 27 | 46 | 73 |
| 2021 November | 22 | 44 | 66 |
| 2021 October | 21 | 44 | 65 |
| 2021 September | 19 | 63 | 82 |
| 2021 August | 14 | 31 | 45 |
| 2021 July | 12 | 28 | 40 |
| 2021 June | 17 | 28 | 45 |
| 2021 May | 16 | 29 | 45 |
| 2021 April | 47 | 78 | 125 |
| 2021 March | 29 | 28 | 57 |
| 2021 February | 19 | 23 | 42 |
| 2021 January | 15 | 15 | 30 |
| 2020 December | 12 | 22 | 34 |
| 2020 November | 13 | 18 | 31 |
| 2020 October | 11 | 16 | 27 |
| 2020 September | 9 | 6 | 15 |
| 2020 August | 12 | 15 | 27 |
| 2020 July | 15 | 22 | 37 |
| 2020 June | 9 | 4 | 13 |
| 2020 May | 15 | 11 | 26 |
| 2020 April | 18 | 23 | 41 |
| 2020 March | 12 | 10 | 22 |
| 2020 February | 20 | 19 | 39 |
| 2020 January | 18 | 18 | 36 |
| 2019 December | 19 | 12 | 31 |
| 2019 November | 17 | 18 | 35 |
| 2019 October | 9 | 12 | 21 |
| 2019 September | 11 | 9 | 20 |
| 2019 August | 18 | 8 | 26 |
| 2019 July | 11 | 14 | 25 |
| 2019 June | 10 | 9 | 19 |
| 2019 May | 26 | 5 | 31 |
| 2019 April | 53 | 13 | 66 |
| 2019 March | 24 | 11 | 35 |
| 2019 February | 21 | 16 | 37 |
| 2019 January | 23 | 8 | 31 |
| 2018 December | 26 | 17 | 43 |
| 2018 November | 33 | 17 | 50 |
| 2018 October | 16 | 6 | 22 |
| 2018 September | 13 | 10 | 23 |
| 2018 May | 3 | 1 | 4 |
| 2018 April | 10 | 5 | 15 |
| 2018 March | 8 | 5 | 13 |
| 2018 February | 7 | 5 | 12 |
| 2018 January | 9 | 9 | 18 |
| 2017 December | 9 | 5 | 14 |
| 2017 November | 2 | 4 | 6 |
| 2017 October | 9 | 6 | 15 |
| 2017 September | 3 | 3 | 6 |
| 2017 August | 4 | 7 | 11 |
| 2017 July | 11 | 7 | 18 |
| 2017 June | 8 | 12 | 20 |
| 2017 May | 7 | 5 | 12 |
| 2017 April | 2 | 3 | 5 |
| 2017 March | 4 | 4 | 8 |
| 2017 February | 6 | 9 | 15 |
| 2017 January | 2 | 2 | 4 |
| 2016 December | 6 | 5 | 11 |
| 2016 November | 10 | 5 | 15 |
| 2016 October | 11 | 9 | 20 |
| 2016 September | 12 | 8 | 20 |
| 2016 August | 14 | 3 | 17 |
| 2016 July | 13 | 3 | 16 |
| 2016 March | 4 | 0 | 4 |
| 2016 January | 1 | 0 | 1 |
| 2015 December | 2 | 0 | 2 |
| 2015 October | 29 | 4 | 33 |
| 2015 September | 40 | 6 | 46 |
| 2015 August | 51 | 10 | 61 |
| 2015 July | 41 | 4 | 45 |
| 2015 June | 27 | 2 | 29 |
| 2015 May | 50 | 6 | 56 |
| 2015 April | 33 | 17 | 50 |
| 2015 March | 44 | 5 | 49 |
| 2015 February | 32 | 5 | 37 |
| 2015 January | 26 | 6 | 32 |
| 2014 December | 25 | 4 | 29 |
| 2014 November | 44 | 5 | 49 |
| 2014 October | 47 | 11 | 58 |
| 2014 September | 39 | 9 | 48 |
| 2014 August | 32 | 12 | 44 |
| 2014 July | 40 | 5 | 45 |
| 2014 June | 55 | 13 | 68 |
| 2014 May | 45 | 8 | 53 |
| 2014 April | 53 | 8 | 61 |
| 2014 March | 63 | 7 | 70 |
| 2014 February | 61 | 10 | 71 |
| 2014 January | 45 | 7 | 52 |
| 2013 December | 45 | 9 | 54 |
| 2013 November | 35 | 4 | 39 |
| 2013 October | 40 | 6 | 46 |
| 2013 September | 37 | 6 | 43 |
| 2013 August | 48 | 13 | 61 |
| 2013 July | 47 | 24 | 71 |
| 2013 June | 38 | 7 | 45 |
| 2013 May | 36 | 9 | 45 |
| 2013 April | 22 | 5 | 27 |
| 2013 March | 6 | 3 | 9 |
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