Original Articles
Assessment of Patient Satisfaction and Preferences With Inhalers in Asthma With the FSI-10 Questionnaire
Miguel Perpiñá Torderaa,
, José Luis Viejob, Joaquín Sanchosc, Xavier Badiad, Nicolás Cobose, César Picadof, Víctor Sobradillog, Jaime Martínez González del Ríoh, Fernando Ducei, Luis Muñoz Cabreraj
Corresponding author
perpinya_mig@gva.es
Correspondence: Dr M. Perpiñá Tordera, Servicio de Neumología, Hospital Universitario La Fe, Avda de Campanar, 21, 46009 Valencia, Spain
Correspondence: Dr M. Perpiñá Tordera, Servicio de Neumología, Hospital Universitario La Fe, Avda de Campanar, 21, 46009 Valencia, Spain
a Servicio de Neumología, Hospital Universitario La Fe, Valencia, Spain
b Servicio de Neumología, Hospital General Yagüe, Burgos, Spain
c Servicio de Neumología, Hospital de Sant Pau, Barcelona, Spain
d Health Outcomes Research, Barcelona, Spain
e Unidad de Neumología Pediátrica, Hospital Vail d'Hebron, Barcelona, Spain
f Servicio de Neumología, Hospital Clínic, Barcelona, Spain
g Servicio de Neumología, Hospital de Cruces, Baracaldo, Vizcaya, Spain
h Servicio de Neumología, Hospital Universitario Central de Asturias, Oviedo, Asturias, Spain
i Servicio de Alergia, Hospital Clínico Lozano Blesa, Zaragoza, Spain
j Servicio de Neumología, Hospital Reina Sofía, Córdoba, Spain
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Hospital Universitario Central de Asturias, Oviedo, Asturias, Spain" "etiqueta" => "<span class="elsevierStyleSup">h</span>" "identificador" => "aff8" ] 8 => array:3 [ "entidad" => "Servicio de Alergia, Hospital Clínico Lozano Blesa, Zaragoza, Spain" "etiqueta" => "<span class="elsevierStyleSup">i</span>" "identificador" => "aff9" ] 9 => array:3 [ "entidad" => "Servicio de Neumología, Hospital Reina Sofía, Córdoba, Spain" "etiqueta" => "<span class="elsevierStyleSup">j</span>" "identificador" => "aff10" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "*" "correspondencia" => "Correspondence: Dr M. Perpiñá Tordera, Servicio de Neumología, Hospital Universitario La Fe, Avda de Campanar, 21, 46009 Valencia, Spain" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2007-05-10" "fechaAceptado" => "2008-02-05" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec155300" "palabras" => array:4 [ 0 => "<span class="elsevierStyleItalic">Preference</span>" 1 => "<span class="elsevierStyleItalic">Inhalation devices</span>" 2 => "<span class="elsevierStyleItalic">Corticosteroids</span>" 3 => "<span class="elsevierStyleItalic">Asthma</span>" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec155299" "palabras" => array:4 [ 0 => "Preferencias" 1 => "Dispositivos de inhalacion" 2 => "Corticoides" 3 => "Asma" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Background and objective</span><p class="elsevierStyleSimplePara elsevierViewall">Lack of adherence to inhaled corticosteroid therapy is common in patients with asthma, and it has been suggested that allowing patients to choose their own inhalers would resolve this problem. The FSI-10 (Feeling of Satisfaction with Inhaler) is a self-completed questionnaire to assess patient opinions regarding ease or difficulty of use, portability, and usability of devices for delivery of inhaled corticosteroids. The aim of this study was to define the measurement properties of the FSI-10 questionnaire and to use this inventory to compare satisfaction and preferences of patients with asthma regarding 3 different devices for delivery of inhaled corticosteroids: Turbuhaler, Accuhaler, and Novolizer.</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p class="elsevierStyleSimplePara elsevierViewall">We performed a multicenter, prospective, observational study in 112 stable asthmatic patients (64 women; mean [SD] age, 37 [22] years) treated on a regular basis with inhaled corticosteroids. The use of the devices was explained to the patients and the order in which they should be used in each case was randomly assigned. The devices were used for 7-day periods and at the end of each the FSI-10 questionnaire was completed for the device used. Once the protocol was completed, patients stated their preference for the different devices used.</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">The FSI-10 was easily understood and rapidly completed, and it exhibited acceptable measurement properties. Factor analysis showed that the measure was unidimensional. Although acceptance of all 3 devices assessed was reasonable, the FSI-10 questionnaire detected significant differences between them: Turbuhaler and Novolizer scored higher than Accuhaler on a number of questions. This preference is partly explained by Turbuhaler having been the device that was commonly used by the patients prior to the study. However, the highest scoring and most often preferred inhaler in patients under 16 years of age was the Novolizer, even though the Turbuhaler had also usually been used by those patients prior to the study.</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">The FSI-10 is a useful instrument for assessing the degree of satisfaction of asthmatic patients regarding available inhalation devices. It is easy to understand and complete, and able to identify differences in patient satisfaction with the different inhalers.</p>" ] "es" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Antecedentes y objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">El incumplimiento terapéutico con los corticoides inhalados (CI) es frecuente en los pacientes con asma. Se ha señalado que la elección del dispensador por el paciente facilitaría la solución del problema. El FSI-10 (Evaluación de la Satisfacción con el Inhalador) es un cuestionario autorrellenable que valora las opiniones sobre comodidad, dificultad, transportabilidad y manejabilidad de los dispositivos para CI. El objetivo de este trabajo ha sido definir las propiedades métricas del FSI-10 y comparar, mediante este inventario, la satisfacción y las preferencias de los pacientes con asma respecto a 3 dispositivos para CI: Turbuhaler® (T), Accuhaler® (A) y Novolizer® (N).</p> <span class="elsevierStyleSectionTitle">Pacientes y métodos</span><p class="elsevierStyleSimplePara elsevierViewall">Hemos realizado un estudio observacional, prospectivo y multicéntrico en 112 asmáticos (64 mujeres; edad media ± desviación estándar: 37 ± 22 años) estables y tratados regularmente con CI. Se les explicó la técnica de utilizatión de los dispositivos a evaluar y, aleatoriamente, se asignó el orden en que debían emplearlos. Usaron los dispositivos durante períodos de 7 días, tras los cuales cumplimentaron el FSI-10. Completado el protocolo, todos ellos expresaron el grado de preferencia por los dispositivos empleados.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">El FSI-10 resultó fácil de comprender y rápido de cumplimentar, y mostró propiedades métricas aceptables. El analisis factorial exploratorio muestra la unidimensionalidad de la medida. La aceptacion de los 3 dispositivos evaluados fue razonable, pero el FSI-10 detect» diferencias signiflcativas entre ellos: los sistemas T y N se valoraron mejor que A en bastantes preguntas del cuestionario. Esta pre-ferencia responde en parte al hecho de que T era el dispositi-vo comunmente utilizado con anterioridad por los pacientes. Sin embargo, para los menores de 16 afios el inhalador prefe-rido y mejor puntuado fue N, a pesar de que en este subgrupo tambien era el T el habitualmente manejado.</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">El FSI-10 es un instrumento util para evaluar el grado de satisfaction del paciente asmatico con los dispositivos de inhalacion disponibles. Es comprensible, de facil manejo y capaz de identificar diferencias de satisfaccion entre distintos inhaladores.</p>" ] ] "NotaPie" => array:1 [ 0 => array:1 [ "nota" => "<p class="elsevierStyleNotepara">This study was funded by Meda Pharma and grant FIS PI05/0583 from the Health Research Fund of the Spanish Ministry of Health.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:20 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "New trends in aerosol therapy: the clinicians view" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "J Sanchis" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Eur Respir Rev" "fecha" => "1994" "volumen" => "18" "paginaInicial" => "106" "paginaFinal" => "107" ] ] ] ] ] ] 1 => array:3 [ "identificador" 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| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 4 | 2 | 6 |
| 2024 October | 31 | 14 | 45 |
| 2024 September | 36 | 14 | 50 |
| 2024 August | 37 | 41 | 78 |
| 2024 July | 27 | 25 | 52 |
| 2024 June | 35 | 26 | 61 |
| 2024 May | 46 | 28 | 74 |
| 2024 April | 22 | 27 | 49 |
| 2024 March | 17 | 19 | 36 |
| 2024 February | 21 | 21 | 42 |
| 2023 May | 0 | 2 | 2 |
| 2023 March | 4 | 7 | 11 |
| 2023 February | 16 | 15 | 31 |
| 2023 January | 15 | 48 | 63 |
| 2022 December | 19 | 41 | 60 |
| 2022 November | 25 | 25 | 50 |
| 2022 October | 29 | 33 | 62 |
| 2022 September | 20 | 22 | 42 |
| 2022 August | 21 | 33 | 54 |
| 2022 July | 21 | 39 | 60 |
| 2022 June | 15 | 33 | 48 |
| 2022 May | 20 | 27 | 47 |
| 2022 April | 16 | 27 | 43 |
| 2022 March | 22 | 40 | 62 |
| 2022 February | 22 | 20 | 42 |
| 2022 January | 14 | 36 | 50 |
| 2021 December | 26 | 60 | 86 |
| 2021 November | 22 | 46 | 68 |
| 2021 October | 27 | 55 | 82 |
| 2021 September | 22 | 55 | 77 |
| 2021 August | 15 | 42 | 57 |
| 2021 July | 15 | 36 | 51 |
| 2021 June | 23 | 33 | 56 |
| 2021 May | 19 | 36 | 55 |
| 2021 April | 61 | 115 | 176 |
| 2021 March | 40 | 17 | 57 |
| 2021 February | 17 | 27 | 44 |
| 2021 January | 15 | 23 | 38 |
| 2020 December | 12 | 26 | 38 |
| 2020 November | 6 | 14 | 20 |
| 2020 October | 14 | 14 | 28 |
| 2020 September | 5 | 9 | 14 |
| 2020 August | 10 | 15 | 25 |
| 2020 July | 12 | 20 | 32 |
| 2020 June | 12 | 7 | 19 |
| 2020 May | 19 | 30 | 49 |
| 2020 April | 20 | 28 | 48 |
| 2020 March | 13 | 13 | 26 |
| 2020 February | 18 | 21 | 39 |
| 2020 January | 19 | 23 | 42 |
| 2019 December | 18 | 21 | 39 |
| 2019 November | 14 | 17 | 31 |
| 2019 October | 6 | 14 | 20 |
| 2019 September | 12 | 22 | 34 |
| 2019 August | 14 | 22 | 36 |
| 2019 July | 9 | 24 | 33 |
| 2019 June | 10 | 11 | 21 |
| 2019 May | 13 | 10 | 23 |
| 2019 April | 27 | 17 | 44 |
| 2019 March | 21 | 26 | 47 |
| 2019 February | 17 | 10 | 27 |
| 2019 January | 9 | 16 | 25 |
| 2018 December | 7 | 21 | 28 |
| 2018 November | 22 | 31 | 53 |
| 2018 October | 41 | 25 | 66 |
| 2018 September | 40 | 21 | 61 |
| 2018 May | 6 | 1 | 7 |
| 2018 April | 10 | 11 | 21 |
| 2018 March | 6 | 5 | 11 |
| 2018 February | 6 | 7 | 13 |
| 2018 January | 8 | 6 | 14 |
| 2017 December | 4 | 17 | 21 |
| 2017 November | 6 | 37 | 43 |
| 2017 October | 7 | 38 | 45 |
| 2017 September | 6 | 26 | 32 |
| 2017 August | 8 | 34 | 42 |
| 2017 July | 4 | 20 | 24 |
| 2017 June | 13 | 65 | 78 |
| 2017 May | 3 | 25 | 28 |
| 2017 April | 1 | 45 | 46 |
| 2017 March | 7 | 49 | 56 |
| 2017 February | 2 | 30 | 32 |
| 2017 January | 3 | 22 | 25 |
| 2016 December | 6 | 17 | 23 |
| 2016 November | 11 | 27 | 38 |
| 2016 October | 16 | 25 | 41 |
| 2016 September | 23 | 18 | 41 |
| 2016 August | 38 | 11 | 49 |
| 2016 July | 9 | 18 | 27 |
| 2016 March | 1 | 0 | 1 |
| 2016 February | 1 | 0 | 1 |
| 2015 December | 2 | 0 | 2 |
| 2015 October | 83 | 13 | 96 |
| 2015 September | 69 | 9 | 78 |
| 2015 August | 48 | 9 | 57 |
| 2015 July | 107 | 11 | 118 |
| 2015 June | 53 | 7 | 60 |
| 2015 May | 58 | 14 | 72 |
| 2015 April | 56 | 11 | 67 |
| 2015 March | 65 | 7 | 72 |
| 2015 February | 43 | 3 | 46 |
| 2015 January | 49 | 7 | 56 |
| 2014 December | 56 | 7 | 63 |
| 2014 November | 70 | 5 | 75 |
| 2014 October | 101 | 11 | 112 |
| 2014 September | 72 | 3 | 75 |
| 2014 August | 60 | 16 | 76 |
| 2014 July | 60 | 14 | 74 |
| 2014 June | 74 | 13 | 87 |
| 2014 May | 75 | 17 | 92 |
| 2014 April | 80 | 6 | 86 |
| 2014 March | 86 | 14 | 100 |
| 2014 February | 76 | 12 | 88 |
| 2014 January | 57 | 9 | 66 |
| 2013 December | 61 | 5 | 66 |
| 2013 November | 47 | 10 | 57 |
| 2013 October | 71 | 11 | 82 |
| 2013 September | 61 | 11 | 72 |
| 2013 August | 59 | 22 | 81 |
| 2013 July | 69 | 12 | 81 |
| 2013 June | 58 | 13 | 71 |
| 2013 May | 61 | 10 | 71 |
| 2013 April | 33 | 11 | 44 |
| 2013 March | 9 | 5 | 14 |
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