Original Articles
Image-Guided Minimally Invasive Treatment of Pulmonary Arterial Hypertension Due to Embolic Disease
Miguel Ángel de Gregorioa,
, Alicia Labordaa, Rosario Ortasa, Teresa Higuerab, Javier Gómez-Arruea, Joaquín Medranoa, Antonio Mainara
Corresponding author
mgregori@unizar.es
Correspondence: Dr M.A. de Gregorio Unidad de Cirugía Mínimamente Invasiva Guiada por Imagen Hospital Clínico Universitario Lozano Blesa. Juan Bosco, 1550006 Zaragoza. Spain
Correspondence: Dr M.A. de Gregorio Unidad de Cirugía Mínimamente Invasiva Guiada por Imagen Hospital Clínico Universitario Lozano Blesa. Juan Bosco, 1550006 Zaragoza. Spain
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Gregorio, Alicia Laborda, Rosario Ortas, Teresa Higuera, Javier Gómez-Arrue, Joaquín Medrano, Antonio Mainar" "autores" => array:7 [ 0 => array:4 [ "nombre" => "Miguel Ángel" "apellidos" => "de Gregorio" "email" => array:1 [ 0 => "mgregori@unizar.es" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor1" ] ] ] 1 => array:3 [ "nombre" => "Alicia" "apellidos" => "Laborda" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 2 => array:3 [ "nombre" => "Rosario" "apellidos" => "Ortas" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 3 => array:3 [ "nombre" => "Teresa" "apellidos" => "Higuera" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] ] 4 => array:3 [ "nombre" => "Javier" "apellidos" => "Gómez-Arrue" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 5 => array:3 [ "nombre" => "Joaquín" "apellidos" => "Medrano" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 6 => array:3 [ "nombre" => "Antonio" "apellidos" => "Mainar" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Unidad de Cirugía Mínimamente Invasiva Guiada por Imagen, Hospital Clínico Universitario Lozano Blesa, Zaragoza, Spain" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:3 [ "entidad" => "Unidad de Hemodinámica, Hospital Clínico Universitario Lozano Blesa, Zaragoza, Spain" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "*" "correspondencia" => "Correspondence: Dr M.A. de Gregorio Unidad de Cirugía Mínimamente Invasiva Guiada por Imagen Hospital Clínico Universitario Lozano Blesa. Juan Bosco, 1550006 Zaragoza. Spain" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec155275" "palabras" => array:3 [ 0 => "Minimally invasive surgical procedures" 1 => "Chronicpulmonary embolic disease" 2 => "Pulmonary artery hypertension" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec155274" "palabras" => array:3 [ 0 => "Mínima invasión" 1 => "Embolia pulmonar crónica" 2 => "Hipertensión arterial pulmonar" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">Although surgical pulmonarythromboendarterectomy is the treatment of choice forpulmonary hypertension due to chronic thrombotic and/orembolic disease, minimally invasive endovasculartechniques such as angioplasty or placement of a metallicstent can provide acceptable results when surgery is notindicated or has been refused by the patient.</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p class="elsevierStyleSimplePara elsevierViewall">Eight patients (5 men, 3 women;mean age, 62.6 years) were treated. The patients were in New York Heart Association (NYHA) class III or IV andhad a mean pulmonary artery pressure of 40 mm Hg ormore, a capillary wedge pressure of 15 mm Hg or less, and a Miller index greater than 0.5. In all cases, diagnosis was based on Doppler echocardiography, pulmonaryangiography, hemodynamic evaluation, and ventilation-perfusion scintigraphy. All patients received fibrinolytictherapy and underwent angioplasty. A metallic stent wasimplanted in 3 patients. Follow-up echocardiographicassessment and ventilation-perfusion scans were scheduledat 1, 3, 6, and 12 months.</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">The procedures were technically successful in allcases. The mean follow-up period was 18.7 months. Minorcomplications were extrasystoles (3 cases), slight bruising atthe site of puncture (1 case), and rectal bleeding thatresolved without treatment (1 case). One patient died froman unknown cause 24 hours after the procedure. In all othercases, improvements were noted in NYHA functional class, in hemodynamics demonstrated by echocardiography, andin vascular structure as shown by arteriography andscintigraphy.</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">Minimally invasive endovascularinterventions can help improve pulmonary arterialhypertension due to chronic thrombotic and/or embolicdisease in patients for whom medical or surgical treatmentis not possible.</p>" ] "es" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">Aunque la tromboendarterectomía pulmonarquirúrgica es el tratamiento de elección en la hipertensiónarterial crónica de origen tromboembólico, cuando no hayindicación quirúrgica o el paciente rechaza la cirugía sepuede recurrir a técnicas endovasculares de mínima inva-sión (angioplastia y prótesis metálica) con aceptables resul-tados.</p> <span class="elsevierStyleSectionTitle">Pacientes y métodos</span><p class="elsevierStyleSimplePara elsevierViewall">Se trató a 8 pacientes (5 varones y3 mujeres) con una media de edad de 62,6 años, en clase IIIo IV de la clasificación de la New York Heart Association(NYHA), con presión arterial pulmonar media de 40 mmHgo superior, presión capilar enclavada de 15 mmHg o menore índice de Miller mayor de 0,5. En todos los casos el diag-nóstico se estableció por ecografía Doppler cardíaca, angio-grafía pulmonar, estudio hemodinámico y gammagrafía deventilación-perfusión. Se realizó tratamiento fibrinolítico se-guido de angioplastia en todos los casos, y se colocó una pró-tesis metálica en 3. Se realizaron revisiones clínicas al cabode 1, 3, 6 y 12 meses mediante ecografía y gammagrafía.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">El éxito técnico del procedimiento fue del100%. El seguimiento medio fue de 18,7 meses. Como com-plicaciones menores se produjeron extrasístoles en 3 casos;hematoma leve en la zona de punción en un caso, y rectorra-gia, que remitió sin tratamiento, en otro. Una paciente mu-rió por causa desconocida al cabo de 24 h. En todos los casosrevisados se observaron una mejoría en la clasificación de laNYHA, mejora hemodinámica evidenciada por ecografía ymejora morfológica objetivada por arteriografía y gamma-grafía.</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">Las técnicas endovasculares de mínimainvasión pueden contribuir a mejorar la hipertensión arte-rial pulmonar crónica debida a tromboembolia en la que noes posible otro tratamiento (farmacológico o quirúrgico).</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:26 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Diagnosis and management of pulmonary arterial hypertension: ACCP evidence-based clinical practice guidelines" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "LJ Rubin" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1378/chest.126.1_suppl.7S" "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "2004" "volumen" => "126" "paginaInicial" => "7S" "paginaFinal" => "10S" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15249491" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Primary pulmonary hypertension: a national prospective study" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "S Rich" 1 => "DR Dantzker" 2 => "SM Ayres" 3 => "E Bergofsky" 4 => "BH Brundage" 5 => "KM Detr" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Ann Intern Med" "fecha" => "1987" "volumen" => "107" "paginaInicial" => "216" "paginaFinal" => "223" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3605900" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib3" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "ACCP consensus statement: primary pulmonary hypertension" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "LJ Rubin" 1 => "RJ Barst" 2 => "LR Kaiser" 3 => "SK Koerner" 4 => "JE Loyd" 5 => "MD McGoon" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "1993" "volumen" => "104" "paginaInicial" => "236" "paginaFinal" => "250" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8325077" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib4" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Surgical treatments/interventions for pulmonary arterial hypertension. ACCP evidence-based clinical practice guidelines" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "RM Doyle" 1 => "D McCrory" 2 => "RN Channick" 3 => "G Simonneau" 4 => "J Cont" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1378/chest.126.1_suppl.63S" "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "2004" "volumen" => "126" "paginaInicial" => "63S" "paginaFinal" => "71S" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15249495" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib5" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Long-term outcome after pulmonary thromboendarterectomy" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "CJ Archibald" 1 => "WR Auger" 2 => "PF Fedullo" 3 => "RN Channick" 4 => "KM Kerr" 5 => "SW Jamieson" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/ajrccm.160.2.9808109" "Revista" => array:6 [ "tituloSerie" => "Am J Respir Crit Care Med" "fecha" => "1999" "volumen" => "160" "paginaInicial" => "523" "paginaFinal" => "528" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10430723" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib6" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:1 [ "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "American Heart Association" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:4 [ "titulo" => "Revisions to classification of functional capacity and objective assessment of patients with disease of the heart. Nomenclature and criteria for diagnosis of diseases of the heart and great vessels" "fecha" => "1994" "editorial" => "Little Brown & Co." "editorialLocalizacion" => "New York" ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib7" "etiqueta" => "7" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Chronic thromboembolic pulmonary hypertension" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "PF Fedullo" 1 => "WR Auger" 2 => "KM Kerr" 3 => "LJ Rubin" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1056/NEJMra010902" "Revista" => array:6 [ "tituloSerie" => "N Engl J Med" "fecha" => "2001" "volumen" => "345" "paginaInicial" => "1465" "paginaFinal" => "1472" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11794196" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib8" "etiqueta" => "8" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Chronic thromboembolic pulmonary hypertension – not so rare after all" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "IM Lang" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1056/NEJMp048088" "Revista" => array:6 [ "tituloSerie" => "N Engl J Med" "fecha" => "2004" "volumen" => "350" "paginaInicial" => "2236" "paginaFinal" => "2238" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15163772" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib9" "etiqueta" => "9" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Incidence of chronic thromboembolic pulmonary hypertension after pulmonary embolism" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "V Pengo" 1 => "AW Lensing" 2 => "MH Prins" 3 => "A Marchiori" 4 => "BL Davidson" 5 => "F Tiozzo" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1056/NEJMoa032274" "Revista" => array:6 [ "tituloSerie" => "N Engl J Med" "fecha" => "2004" "volumen" => "350" "paginaInicial" => "2257" "paginaFinal" => "2264" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15163775" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib10" "etiqueta" => "10" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Chronic, massive thrombotic obstruction of the pulmonary arteries: analysis of four operated cases" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "KM Moser" 1 => "VN Houk" 2 => "RC Jones" 3 => "CC Hufnagel" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Circulation" "fecha" => "1965" "volumen" => "32" "paginaInicial" => "377" "paginaFinal" => "385" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5830602" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0140673606685541" "estado" => "S300" "issn" => "01406736" ] ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib11" "etiqueta" => "11" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pulmonary endarterectomy: experience and lessons learned in 1,500 cases" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "SW Jamieson" 1 => "DP Kapelanski" 2 => "N Sakakibara" 3 => "GR Menecke" 4 => "PA Thistlewaite" 5 => "KM Kerr" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Ann Thorac Surg" "fecha" => "2003" "volumen" => "76" "paginaInicial" => "1457" "paginaFinal" => "1464" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14602267" "web" => "Medline" ] ] ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib12" "etiqueta" => "12" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Hemodynamic effects of nonionic contrast bolus injection and oxygen inhalation during pulmonary angiography in patients with chronic major vessel thromboembolic pulmonary hypertension" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "MB Pitton" 1 => "C Düber" 2 => "E Mayer" 3 => "M Thelen" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Circulation" "fecha" => "1996" "volumen" => "94" "paginaInicial" => "2485" "paginaFinal" => "2491" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8921792" "web" => "Medline" ] ] ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib13" "etiqueta" => "13" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pulmonary thromboendarterectomy in patients with chronic thromboembolic hypertension: hemodynamic characteristics and changes" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "A D'Armini" 1 => "B Cattadori" 2 => "C Monterosso" 3 => "C Klersy" 4 => "V Emmi" 5 => "F Piovella" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Eur J Cardiothorac Surg" "fecha" => "2000" "volumen" => "18" "paginaInicial" => "696" "paginaFinal" => "702" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11113678" "web" => "Medline" ] ] ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib14" "etiqueta" => "14" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Acute and chronic effects of surgical thromboendarterectomy on exercise capacity and ventilatory efficiency in patients with chronic thromboembolic hypertension" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "T Iwase" 1 => "N Nagaya" 2 => "M Ando" 3 => "T Satoh" 4 => "F Sakamaki" 5 => "S Kyotani" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Heart" "fecha" => "2001" "volumen" => "86" "paginaInicial" => "188" "paginaFinal" => "192" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11454839" "web" => "Medline" ] ] ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib15" "etiqueta" => "15" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Surgical treatment of chronic thromboembolic pulmonary hypertension" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "F Rubens" 1 => "P Wells" 2 => "S Bencze" 3 => "M Bourke" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Can Respir J" "fecha" => "2000" "volumen" => "7" "paginaInicial" => "49" "paginaFinal" => "57" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10700671" "web" => "Medline" ] ] ] ] ] ] ] ] 15 => array:3 [ "identificador" => "bib16" "etiqueta" => "16" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Mid-term effects of pulmonary thromboendarterectomy on clinical and cardiopulmonary function status" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "M Zoia" 1 => "A D'Armini" 2 => "M Beccaria" 3 => "A Corsico" 4 => "P Fulgoni" 5 => "C Klersy" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Thorax" "fecha" => "2002" "volumen" => "57" "paginaInicial" => "608" "paginaFinal" => "612" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12096204" "web" => "Medline" ] ] ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bib17" "etiqueta" => "17" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Mid-term results of pulmonary thromboendarterectomy for chronic thromboembolic pulmonary hypertension" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "E Mayer" 1 => "M Dahm" 2 => "U Hake" 3 => "FX Schmid" 4 => "M Pitton" 5 => "I Kupferwasser" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/0003-4975(96)00169-5" "Revista" => array:6 [ "tituloSerie" => "Ann Thorac Surg" "fecha" => "1996" "volumen" => "61" "paginaInicial" => "1788" "paginaFinal" => "1792" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8651785" "web" => "Medline" ] ] ] ] ] ] ] ] 17 => array:3 [ "identificador" => "bib18" "etiqueta" => "18" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The Seventh ACCP Conference on antithrombotic and thrombolytic therapy. Evidence-based guidelines" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "J Hirsh" 1 => "G Guyatt" 2 => "GW Albers" 3 => "HJ Schünemann" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1378/chest.126.3_suppl.172S" "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "2004" "volumen" => "126" "paginaInicial" => "172S" "paginaFinal" => "173S" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15383469" "web" => "Medline" ] ] ] ] ] ] ] ] 18 => array:3 [ "identificador" => "bib19" "etiqueta" => "19" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Balloon pulmonary angioplasty for treatment of chronic thromboembolic pulmonary hypertension" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "JA Feinstein" 1 => "S Goldhaber" 2 => "JE Lock" 3 => "SM Ferndandes" 4 => "MJ Landzberg" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Circulation" "fecha" => "2001" "volumen" => "103" "paginaInicial" => "10" "paginaFinal" => "13" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11136677" "web" => "Medline" ] ] ] ] ] ] ] ] 19 => array:3 [ "identificador" => "bib20" "etiqueta" => "20" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Mechanical and enzymatic thrombolysis for massive pulmonary embolism" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "MAD Gregorio" 1 => "MJ Gimeno" 2 => "A Mainar" 3 => "M Herrera" 4 => "R Tobío" 5 => "R Alfonso" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Vasc Interv Radiol" "fecha" => "2000" "volumen" => "13" "paginaInicial" => "163" "paginaFinal" => "169" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11830622" "web" => "Medline" ] ] ] ] ] ] ] ] 20 => array:3 [ "identificador" => "bib21" "etiqueta" => "21" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Life threatening pulmonary emboli and cor pulmonale: treatment with percutaneous pulmonary artery stent placement" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "ZJ Haskal" 1 => "MC Soulen" 2 => "EA Huettl" 3 => "HI Palevsky" 4 => "C Cope" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1148/radiology.191.2.8153324" "Revista" => array:6 [ "tituloSerie" => "Radiology" "fecha" => "1994" "volumen" => "191" "paginaInicial" => "473" "paginaFinal" => "475" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8153324" "web" => "Medline" ] ] ] ] ] ] ] ] 21 => array:3 [ "identificador" => "bib22" "etiqueta" => "22" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Temporary pulmonary stent placement as emergency treatment of pulmonary embolism: first experimental evaluation" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "T Schmitz-Rode" 1 => "R Verma" 2 => "JG Pfeffer" 3 => "RD Hilgers" 4 => "RW Gunther" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.jacc.2006.04.079" "Revista" => array:6 [ "tituloSerie" => "J Am Coll Cardiol" "fecha" => "2006" "volumen" => "48" "paginaInicial" => "812" "paginaFinal" => "816" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16904554" "web" => "Medline" ] ] ] ] ] ] ] ] 22 => array:3 [ "identificador" => "bib23" "etiqueta" => "23" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Retrieval of Günther tulip optional vena cava filter 30 days after implantation – a prospective clinical study" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "MA de Gregorio" 1 => "P Gamboa" 2 => "D Bonilla" 3 => "M Sánchez" 4 => "T Higuera" 5 => "J Medrano" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/01.RVI.0000244837.46324.72" "Revista" => array:6 [ "tituloSerie" => "J Vasc Interv Radiol" "fecha" => "2006" "volumen" => "17" "paginaInicial" => "1781" "paginaFinal" => "1789" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17142708" "web" => "Medline" ] ] ] ] ] ] ] ] 23 => array:3 [ "identificador" => "bib24" "etiqueta" => "24" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Balloon angioplasty and stenting of multiple intralobar pulmonary arterial stenoses in adult patients" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "A Rothman" 1 => "DJ Levy" 2 => "MS Sklansky" 3 => "PD Grossfeld" 4 => "WR Auger" 5 => "GH Ajami" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1002/ccd.10407" "Revista" => array:6 [ "tituloSerie" => "Catheter Cardiovasc Interv" "fecha" => "2003" "volumen" => "58" "paginaInicial" => "252" "paginaFinal" => "260" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12552552" "web" => "Medline" ] ] ] ] ] ] ] ] 24 => array:3 [ "identificador" => "bib25" "etiqueta" => "25" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pulmonary arterial stent implantation in an adult with Williams syndrome" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "HJ Reesink" 1 => "OD Henneman" 2 => "OM van Delden" 3 => "JD Biervliet" 4 => "JJ Kloek" 5 => "JA Reekers" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1007/s00270-007-9009-6" "Revista" => array:6 [ "tituloSerie" => "Cardiovasc Intervent Radiol" "fecha" => "2007" "volumen" => "30" "paginaInicial" => "782" "paginaFinal" => "785" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17401760" "web" => "Medline" ] ] ] ] ] ] ] ] 25 => array:3 [ "identificador" => "bib26" "etiqueta" => "26" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Hipertensión pulmonar: eficacia clínica del sildenafilo en clases funcionales II-III" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "I Otero González" 1 => "M Blanco Aparicio" 2 => "A Souto Alonso" 3 => "I Raposo Sonnenfeld" 4 => "V Verea Hernando" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Arch Bronconeumol" "fecha" => "2007" "volumen" => "43" "paginaInicial" => "272" "paginaFinal" => "276" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17519138" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0300289608000318" "estado" => "S300" "issn" => "03002896" ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15792129/0000004400000006/v1_201305150352/S1579212908600518/v1_201305150352/en/main.assets" "Apartado" => null "PDF" => "https://static.elsevier.es/multimedia/15792129/0000004400000006/v1_201305150352/S1579212908600518/v1_201305150352/en/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212908600518?idApp=UINPBA00003Z" ]
| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 3 | 5 | 8 |
| 2024 October | 38 | 24 | 62 |
| 2024 September | 35 | 17 | 52 |
| 2024 August | 44 | 28 | 72 |
| 2024 July | 26 | 19 | 45 |
| 2024 June | 29 | 25 | 54 |
| 2024 May | 47 | 36 | 83 |
| 2024 April | 20 | 24 | 44 |
| 2024 March | 24 | 18 | 42 |
| 2024 February | 25 | 18 | 43 |
| 2023 March | 2 | 4 | 6 |
| 2023 February | 22 | 19 | 41 |
| 2023 January | 17 | 25 | 42 |
| 2022 December | 17 | 20 | 37 |
| 2022 November | 25 | 15 | 40 |
| 2022 October | 29 | 28 | 57 |
| 2022 September | 15 | 19 | 34 |
| 2022 August | 23 | 28 | 51 |
| 2022 July | 21 | 45 | 66 |
| 2022 June | 23 | 27 | 50 |
| 2022 May | 22 | 27 | 49 |
| 2022 April | 21 | 23 | 44 |
| 2022 March | 24 | 38 | 62 |
| 2022 February | 16 | 18 | 34 |
| 2022 January | 22 | 33 | 55 |
| 2021 December | 15 | 43 | 58 |
| 2021 November | 29 | 47 | 76 |
| 2021 October | 21 | 50 | 71 |
| 2021 September | 19 | 62 | 81 |
| 2021 August | 21 | 31 | 52 |
| 2021 July | 12 | 16 | 28 |
| 2021 June | 17 | 31 | 48 |
| 2021 May | 18 | 43 | 61 |
| 2021 April | 35 | 29 | 64 |
| 2021 March | 30 | 18 | 48 |
| 2021 February | 20 | 23 | 43 |
| 2021 January | 8 | 10 | 18 |
| 2020 December | 14 | 15 | 29 |
| 2020 November | 11 | 17 | 28 |
| 2020 October | 19 | 7 | 26 |
| 2020 September | 7 | 3 | 10 |
| 2020 August | 15 | 18 | 33 |
| 2020 July | 11 | 17 | 28 |
| 2020 June | 19 | 4 | 23 |
| 2020 May | 13 | 16 | 29 |
| 2020 April | 19 | 19 | 38 |
| 2020 March | 13 | 14 | 27 |
| 2020 February | 22 | 15 | 37 |
| 2020 January | 21 | 18 | 39 |
| 2019 December | 17 | 14 | 31 |
| 2019 November | 12 | 11 | 23 |
| 2019 October | 6 | 7 | 13 |
| 2019 September | 3 | 5 | 8 |
| 2019 August | 16 | 8 | 24 |
| 2019 July | 6 | 11 | 17 |
| 2019 June | 5 | 8 | 13 |
| 2019 May | 10 | 8 | 18 |
| 2019 April | 20 | 18 | 38 |
| 2019 March | 14 | 15 | 29 |
| 2019 February | 9 | 6 | 15 |
| 2019 January | 3 | 6 | 9 |
| 2018 December | 7 | 14 | 21 |
| 2018 November | 30 | 13 | 43 |
| 2018 October | 26 | 10 | 36 |
| 2018 September | 12 | 13 | 25 |
| 2018 May | 6 | 0 | 6 |
| 2018 April | 10 | 5 | 15 |
| 2018 March | 9 | 3 | 12 |
| 2018 February | 3 | 4 | 7 |
| 2018 January | 15 | 9 | 24 |
| 2017 December | 5 | 4 | 9 |
| 2017 November | 1 | 2 | 3 |
| 2017 October | 10 | 10 | 20 |
| 2017 September | 8 | 5 | 13 |
| 2017 August | 13 | 10 | 23 |
| 2017 July | 14 | 11 | 25 |
| 2017 June | 15 | 9 | 24 |
| 2017 May | 5 | 3 | 8 |
| 2017 April | 3 | 0 | 3 |
| 2017 March | 4 | 5 | 9 |
| 2017 February | 4 | 1 | 5 |
| 2017 January | 1 | 2 | 3 |
| 2016 December | 6 | 10 | 16 |
| 2016 November | 10 | 12 | 22 |
| 2016 October | 14 | 15 | 29 |
| 2016 September | 13 | 13 | 26 |
| 2016 August | 12 | 2 | 14 |
| 2016 July | 17 | 5 | 22 |
| 2016 March | 2 | 0 | 2 |
| 2015 December | 3 | 0 | 3 |
| 2015 October | 55 | 8 | 63 |
| 2015 September | 61 | 7 | 68 |
| 2015 August | 46 | 6 | 52 |
| 2015 July | 43 | 8 | 51 |
| 2015 June | 31 | 3 | 34 |
| 2015 May | 53 | 5 | 58 |
| 2015 April | 38 | 7 | 45 |
| 2015 March | 46 | 4 | 50 |
| 2015 February | 60 | 4 | 64 |
| 2015 January | 50 | 3 | 53 |
| 2014 December | 56 | 7 | 63 |
| 2014 November | 109 | 7 | 116 |
| 2014 October | 67 | 9 | 76 |
| 2014 September | 57 | 9 | 66 |
| 2014 August | 55 | 16 | 71 |
| 2014 July | 51 | 5 | 56 |
| 2014 June | 48 | 16 | 64 |
| 2014 May | 68 | 9 | 77 |
| 2014 April | 67 | 5 | 72 |
| 2014 March | 69 | 5 | 74 |
| 2014 February | 59 | 7 | 66 |
| 2014 January | 57 | 10 | 67 |
| 2013 December | 47 | 8 | 55 |
| 2013 November | 51 | 4 | 55 |
| 2013 October | 42 | 8 | 50 |
| 2013 September | 39 | 5 | 44 |
| 2013 August | 32 | 5 | 37 |
| 2013 July | 45 | 7 | 52 |
| 2013 June | 40 | 6 | 46 |
| 2013 May | 34 | 6 | 40 |
| 2013 April | 27 | 2 | 29 |
| 2013 March | 11 | 2 | 13 |
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