array:23 [
  "pii" => "S1579212907601268"
  "issn" => "15792129"
  "doi" => "10.1016/S1579-2129(07)60126-8"
  "estado" => "S300"
  "fechaPublicacion" => "2007-01-01"
  "aid" => "60126"
  "copyright" => "Sociedad Española de Neumología y Cirugía Torácica (SEPAR)"
  "copyrightAnyo" => "2007"
  "documento" => "article"
  "crossmark" => 0
  "subdocumento" => "fla"
  "cita" => "Arch Bronconeumol. 2007;43:549-56"
  "abierto" => array:3 [
    "ES" => false
    "ES2" => false
    "LATM" => false
  ]
  "gratuito" => false
  "lecturas" => array:2 [
    "total" => 2389
    "formatos" => array:3 [
      "EPUB" => 88
      "HTML" => 1689
      "PDF" => 612
    ]
  ]
  "itemSiguiente" => array:18 [
    "pii" => "S157921290760127X"
    "issn" => "15792129"
    "doi" => "10.1016/S1579-2129(07)60127-X"
    "estado" => "S300"
    "fechaPublicacion" => "2007-01-01"
    "aid" => "60127"
    "copyright" => "Sociedad Española de Neumología y Cirugía Torácica (SEPAR)"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Arch Bronconeumol. 2007;43:557-61"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 2878
      "formatos" => array:3 [
        "EPUB" => 88
        "HTML" => 1974
        "PDF" => 816
      ]
    ]
    "en" => array:10 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Original Articles</span>"
      "titulo" => "Pulmonary and Nonpulmonary Alterations in Duchenne Muscular Dystrophy"
      "tienePdf" => "en"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "557"
          "paginaFinal" => "561"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Mar&#237;a Rosa G&#252;ell, M&#243;nica Avendano, Janet Fraser, Roger Goldstein"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "Mar&#237;a Rosa"
              "apellidos" => "G&#252;ell"
            ]
            1 => array:2 [
              "nombre" => "M&#243;nica"
              "apellidos" => "Avendano"
            ]
            2 => array:2 [
              "nombre" => "Janet"
              "apellidos" => "Fraser"
            ]
            3 => array:2 [
              "nombre" => "Roger"
              "apellidos" => "Goldstein"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S157921290760127X?idApp=UINPBA00003Z"
    "url" => "/15792129/0000004300000010/v1_201305150259/S157921290760127X/v1_201305150259/en/main.assets"
  ]
  "itemAnterior" => array:18 [
    "pii" => "S1579212907601256"
    "issn" => "15792129"
    "doi" => "10.1016/S1579-2129(07)60125-6"
    "estado" => "S300"
    "fechaPublicacion" => "2007-01-01"
    "aid" => "60125"
    "copyright" => "Sociedad Espa&#241;ola de Neumolog&#237;a y Cirug&#237;a Tor&#225;cica &#40;SEPAR&#41;"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Arch Bronconeumol. 2007;43:542-8"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 2064
      "formatos" => array:3 [
        "EPUB" => 79
        "HTML" => 1336
        "PDF" => 649
      ]
    ]
    "en" => array:10 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Original Articles</span>"
      "titulo" => "Interleukin-8 Expression in Lung Tissue During Ischemia-Reperfusion"
      "tienePdf" => "en"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "542"
          "paginaFinal" => "548"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Jos&#233; Mar&#237;a Matilla, Mariano Garc&#237;a-Yuste, Mariano S&#225;nchez Crespo, Manuel J&#46; Gayoso, F&#233;lix Heras, Marta Jim&#233;nez Prada, Andr&#233;s Alonso, Guillermo Ramos"
          "autores" => array:8 [
            0 => array:2 [
              "nombre" => "Jos&#233; Mar&#237;a"
              "apellidos" => "Matilla"
            ]
            1 => array:2 [
              "nombre" => "Mariano"
              "apellidos" => "Garc&#237;a-Yuste"
            ]
            2 => array:2 [
              "nombre" => "Mariano S&#225;nchez"
              "apellidos" => "Crespo"
            ]
            3 => array:2 [
              "nombre" => "Manuel J&#46;"
              "apellidos" => "Gayoso"
            ]
            4 => array:2 [
              "nombre" => "F&#233;lix"
              "apellidos" => "Heras"
            ]
            5 => array:2 [
              "nombre" => "Marta Jim&#233;nez"
              "apellidos" => "Prada"
            ]
            6 => array:2 [
              "nombre" => "Andr&#233;s"
              "apellidos" => "Alonso"
            ]
            7 => array:2 [
              "nombre" => "Guillermo"
              "apellidos" => "Ramos"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212907601256?idApp=UINPBA00003Z"
    "url" => "/15792129/0000004300000010/v1_201305150259/S1579212907601256/v1_201305150259/en/main.assets"
  ]
  "en" => array:15 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Original Articles</span>"
    "titulo" => "Trends in Prognostic Factors for Neuroendocrine Lung Tumors"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "549"
        "paginaFinal" => "556"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "Mariano Garc&#237;a-Yuste, Laureano Molins, Jos&#233; M&#46; Matilla, Federico Gonz&#225;lez-Aragoneses, Javier L&#243;pez-Pujol, Guillermo Ramos, Mercedes de la Torre"
        "autores" => array:8 [
          0 => array:4 [
            "nombre" => "Mariano"
            "apellidos" => "Garc&#237;a-Yuste"
            "email" => array:1 [
              0 => "mgyuste2&#64;wanadoo&#46;es"
            ]
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff1"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor1"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "Laureano"
            "apellidos" => "Molins"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff2"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "Jos&#233; M&#46;"
            "apellidos" => "Matilla"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff1"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "Federico"
            "apellidos" => "Gonz&#225;lez-Aragoneses"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">c</span>"
                "identificador" => "aff3"
              ]
            ]
          ]
          4 => array:3 [
            "nombre" => "Javier"
            "apellidos" => "L&#243;pez-Pujol"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">d</span>"
                "identificador" => "aff4"
              ]
            ]
          ]
          5 => array:3 [
            "nombre" => "Guillermo"
            "apellidos" => "Ramos"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff1"
              ]
            ]
          ]
          6 => array:3 [
            "nombre" => "Mercedes"
            "apellidos" => "de la Torre"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">e</span>"
                "identificador" => "aff5"
              ]
            ]
          ]
          7 => array:2 [
            "colaborador" => "members of the Spanish Multicenter Study of Neuroendocrine Lung Tumors of the Spanish Society of Pulmonology and Thoracic Surgery &#40;EMETNE-SEPAR&#41;"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "fn1"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:5 [
          0 => array:3 [
            "entidad" => "Servicio de Cirug&#237;a Tor&#225;cica&#44; Hospital Cl&#237;nico Universitario&#44; Valladolid&#44; Spain"
            "etiqueta" => "<span class="elsevierStyleSup">a</span>"
            "identificador" => "aff1"
          ]
          1 => array:3 [
            "entidad" => "Servicio de Cirug&#237;a Tor&#225;cica&#44; Hospital Sagrado Coraz&#243;n&#44; Barcelona&#44; Spain"
            "etiqueta" => "<span class="elsevierStyleSup">b</span>"
            "identificador" => "aff2"
          ]
          2 => array:3 [
            "entidad" => "Servicio de Cirug&#237;a Tor&#225;cica&#44; Hospital Gregorio Mara&#241;&#243;n&#44; Madrid&#44; Spain"
            "etiqueta" => "<span class="elsevierStyleSup">c</span>"
            "identificador" => "aff3"
          ]
          3 => array:3 [
            "entidad" => "Servicio de Cirug&#237;a Tor&#225;cica&#44; Hospital Reina Sof&#237;a&#44; C&#243;rdoba&#44; Spain"
            "etiqueta" => "<span class="elsevierStyleSup">d</span>"
            "identificador" => "aff4"
          ]
          4 => array:3 [
            "entidad" => "Servicio de Cirug&#237;a Tor&#225;cica&#44; Hospital Juan Canalejo&#44; A Coru&#241;a&#44; Spain"
            "etiqueta" => "<span class="elsevierStyleSup">e</span>"
            "identificador" => "aff5"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor1"
            "etiqueta" => "&#42;"
            "correspondencia" => "Correspondence&#58; Dr&#46; M&#46; Garc&#237;a-Yuste&#46; Servicio de Cirug&#237;a Tor&#225;cica&#46; Hospital Cl&#237;nico Universitario&#46; Ram&#243;n y Cajal&#44; 3&#46; 47005 Valladolid&#46; Espa&#241;a"
          ]
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2006-10-05"
    "fechaAceptado" => "2007-11-22"
    "PalabrasClave" => array:2 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Key words"
          "identificador" => "xpalclavsec154626"
          "palabras" => array:3 [
            0 => "Neuroendocrine lung tumor"
            1 => "Staging"
            2 => "Mediastinal lymph node excision"
          ]
        ]
      ]
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec154625"
          "palabras" => array:3 [
            0 => "Tumor pulmonar neuroendocrino"
            1 => "Estadificaci&#243;n"
            2 => "Disecci&#243;n ganglionar mediast&#237;nica"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "en" => array:1 [
        "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">The aim of this study was to analyze trends in a variety of prognostic factors for neuroendocrine lung carcinomas through analysis of 2 groups of surgically treated patients&#46;</p> <span class="elsevierStyleSectionTitle">PATIENTS AND METHODS</span><p class="elsevierStyleSimplePara elsevierViewall">Group A contained the first 361 patients&#44; treated between 1980 and 1997&#46; That group was analyzed retrospectively and contained 261 patients with typical carcinoid tumors&#44; 43 with atypical carcinoid tumors&#44; 22 with large-cell neuroendocrine carcinoma&#44; and 35 with small-cell neuroendocrine carcinoma&#46; Group B contained 404 patients enrolled prospectively between 1998 and 2002&#58; 308 with typical carcinoid tumors&#44; 49 with atypical carcinoid tumors&#44; 18 with large-cell neuroendocrine carcinoma&#44; and 29 with small-cell neuroendocrine carcinoma&#46; The following clinical variables were considered&#58; sex&#44; mean age&#44; tumor site&#44; tumor size&#44; lymph node involvement&#44; stage&#44; metastasis&#44; and local recurrence&#46; The 1997 TNM classification was used for staging of lung cancer and survival analysis was performed along with assessment of factors influencing survival&#46; Statistical analysis of the data involved univariate and multivariate analysis&#46;</p> <span class="elsevierStyleSectionTitle">RESULTS</span><p class="elsevierStyleSimplePara elsevierViewall">In both groups&#44; significant differences were observed between patients with typical and atypical carcinoid tumors in terms of mean age&#44; tumor size&#44; node involvement&#44; and recurrence&#46; In group A&#44; female sex&#44; node involvement&#44; and recurrence differed between patients with atypical carcinoid tumors and those with large-cell neuroendocrine carcinoma&#59; the same was true for group B&#44; with the exception of lymph node involvement&#46; Node involvement differed between patients with small-cell versus large-cell neuroendocrine carcinoma in group A but not group B&#46;</p><p class="elsevierStyleSimplePara elsevierViewall">Both groups displayed significant differences in overall survival and survival of patients with lymph node involvement between patients with typical and atypical carcinoid tumors and between patients with atypical carcinoid tumors and those with large- cell neuroendocrine carcinoma&#59; no differences were observed between patients with large-cell versus small-cell neuroendocrine carcinoma&#46; Histological type and lymph node involvement had the greatest influence on prognosis in the multivariate analysis&#46;</p> <span class="elsevierStyleSectionTitle">CONCLUSIONS</span><p class="elsevierStyleSimplePara elsevierViewall">A well-defined trend is observed in prognostic factors for neuroendocrine lung tumors&#46; Histological type and lymph node involvement show the greatest influence on survival&#46;</p>"
      ]
      "es" => array:1 [
        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">Este estudio tiene como objetivo determinar la tendencia de distintos factores pron&#243;sticos en carcinomas neuroendocrinos del pulm&#243;n a trav&#233;s del an&#225;lisis de 2 grupos de pacientes tratados quir&#250;rgicamente&#46;</p> <span class="elsevierStyleSectionTitle">PACIENTES Y M&#201;TODOS</span><p class="elsevierStyleSimplePara elsevierViewall">En el grupo A se incluyeron los primeros 361 casos&#44; tratados entre 1980 y 1997 &#8212;261 carcinoides t&#237;picos &#40;CT&#41;&#44; 43 carcinoides at&#237;picos &#40;CA&#41;&#44; 22 carcinomas neuroendocrinos de c&#233;lulas grandes &#40;CNECG&#41; y 35 carcinomas neuroendocrinos de c&#233;lulas peque&#241;as &#40;CNECP&#41;&#8212;&#44; que se estudiaron retrospectivamente&#46; El grupo B estuvo compuesto por 404 casos&#44; recogidos desde 1998 a 2002 &#8212;308 CT&#44; 49 CA&#44; 18 CNECG y 29 CNECP&#8212;&#44; que se estudiaron prospectivamente&#46; Las variables cl&#237;nicas consideradas fueron&#58; sexo&#44; edad media&#44; localizaci&#243;n tumoral&#44; tama&#241;o tumoral&#44; afectaci&#243;n ganglionar&#44; estadio&#44; met&#225;stasis y recurrencia local&#46; Se utiliz&#243; la clasificaci&#243;n TNM del carcinoma broncog&#233;nico de 1997 y se practic&#243; un estudio de supervivencia y de factores que influyen en ella&#46; Se realiz&#243; un an&#225;lisis estad&#237;stico uni y multivariante con los datos obtenidos&#46;</p> <span class="elsevierStyleSectionTitle">RESULTADOS</span><p class="elsevierStyleSimplePara elsevierViewall">Por lo que se refiere al CT y al CA&#44; se observaron diferencias significativas en los 2 grupos de pacientes en cuanto a la edad media&#44; el tama&#241;o tumoral&#44; la afectaci&#243;n ganglionar y la recurrencia&#46; Entre CA y CNECG&#44; el sexo&#44; la afectaci&#243;n ganglionar y la recurrencia difirieron en el grupo A&#59; lo mismo ocurri&#243; en el grupo B&#44; con la excepci&#243;n de la afectaci&#243;n ganglionar&#46; Entre CNECG y CNECP&#44; la diferencia en la afectaci&#243;n ganglionar observada en el grupo A no estuvo presente en los pacientes del grupo B&#46; Respecto a la supervivencia&#44; global y por afectaci&#243;n ganglionar&#44; se observaron diferencias significativas en ambos grupos al comparar CT frente a CA y CA frente a CNECG&#59; no se encontraron diferencias entre CNECG y CNECP&#46; El tipo histol&#243;gico y la afectaci&#243;n ganglionar mostraron la mayor influencia pron&#243;stica en an&#225;lisis multivariante&#46;</p> <span class="elsevierStyleSectionTitle">CONCLUSIONES</span><p class="elsevierStyleSimplePara elsevierViewall">En los carcinomas neuroendocrinos de pulm&#243;n se observa una tendencia definida en sus factores pron&#243;sticos&#46; El tipo histol&#243;gico y la detecci&#243;n de afectaci&#243;n ganglionar se muestran como los factores con mayor influencia en la supervivencia&#46;</p>"
      ]
    ]
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#42;"
        "nota" => "<p class="elsevierStyleNotepara">The names of the EMETNE-SEPAR members are provided at the end of the article&#46;</p>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "REFERENCES"
      "seccion" => array:1 [
        0 => array:1 [
          "bibliografiaReferencia" => array:20 [
            0 => array:3 [
              "identificador" => "bib1"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Survival analysis of 200 pulmonary neuroendocrine tumors with clarification of criteria for atypical carcinoid and its separation from typical carcinoid"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "WD Travis"
                            1 => "W Rush"
                            2 => "DB Flieder"
                            3 => "R Falk"
                            4 => "M Fleming"
                            5 => "A Gal"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Surg Pathol"
                        "fecha" => "1998"
                        "volumen" => "22"
                        "paginaInicial" => "934"
                        "paginaFinal" => "944"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9706973"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib2"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Bronchial carcinoid tumors&#58; surgical management and longterm outcome"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "PL Filosso"
                            1 => "O Rena"
                            2 => "G Donati"
                            3 => "C Casadio"
                            4 => "E Ruffini"
                            5 => "E Papalia"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Thorac Cardiovasc Surg"
                        "fecha" => "2002"
                        "volumen" => "123"
                        "paginaInicial" => "303"
                        "paginaFinal" => "309"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11828290"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib3"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Assessment of outcomes in typical and atypical carcinoids according to latest WHO classification"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M Mezzetti"
                            1 => "F Raveglia"
                            2 => "T Panigalli"
                            3 => "L Giuliani"
                            4 => "F lo Giudice"
                            5 => "S Meda"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Thorac Surg"
                        "fecha" => "2003"
                        "volumen" => "76"
                        "paginaInicial" => "1838"
                        "paginaFinal" => "1842"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14667595"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib4"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Neuroendocrine tumors of the bronchopulmonary tract&#46; A reappraisal of their classification after 20 years"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "WH Warren"
                            1 => "VE Gould"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Surg Clin N Am"
                        "fecha" => "2002"
                        "volumen" => "82"
                        "paginaInicial" => "525"
                        "paginaFinal" => "540"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12371583"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib5"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prognostic factors in neuroendocrine lung tumors&#58; a Spanish multicenter study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:7 [
                            0 => "M Garc&#237;a-Yuste"
                            1 => "JM Matilla"
                            2 => "T &#193;lvarez Gago"
                            3 => "JL Duque"
                            4 => "F Heras"
                            5 => "LJ Cerezal"
                            6 => "the Spanish Multicenter Study of Neuroendocrine Tumors of the Lung &#40;EMETNE-SEPAR&#41;"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Thorac Surg"
                        "fecha" => "2000"
                        "volumen" => "70"
                        "paginaInicial" => "258"
                        "paginaFinal" => "263"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10921719"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib6"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Small cell lung cancer&#58; how should be treated it&#63; What is it&#63;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "RJ Ginsberg"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Thorac Surg"
                        "fecha" => "2000"
                        "volumen" => "70"
                        "paginaInicial" => "1453"
                        "paginaFinal" => "1454"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11093468"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib7"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:1 [
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "WD Travis"
                            1 => "LH Sobin"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:4 [
                        "titulo" => "Histologic typing of lung and pleural tumours&#59; International Histologic Classification of Tumours"
                        "fecha" => "1999"
                        "editorial" => "Springer-Verlag"
                        "editorialLocalizacion" => "New York"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib8"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Clinical-pathologic analysis of 40 patients with large cell neuroendocrine carcinoma of the lung"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "CM Dresler"
                            1 => "JH Ritter"
                            2 => "GA Patterson"
                            3 => "E Ross"
                            4 => "MS Biley"
                            5 => "MR Wick"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Thorac Surg"
                        "fecha" => "1997"
                        "volumen" => "63"
                        "paginaInicial" => "180"
                        "paginaFinal" => "185"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8993262"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib9"
              "etiqueta" => "9"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Revisions in the international system for staging lung cancer"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "CF Mountain"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "1997"
                        "volumen" => "111"
                        "paginaInicial" => "1710"
                        "paginaFinal" => "1717"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9187198"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib10"
              "etiqueta" => "10"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Typical and atypical pulmonary carcinoids&#46; Outcome in patients presenting with regional limph node involvement"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "CHF Thomas"
                            1 => "HD Tazelaar"
                            2 => "JR Jett"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "2001"
                        "volumen" => "119"
                        "paginaInicial" => "1143"
                        "paginaFinal" => "1150"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11296182"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib11"
              "etiqueta" => "11"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Bronchial carcinoid tumors&#58; nodal status and long-term survival after resection"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "G Cardillo"
                            1 => "F Sera"
                            2 => "M Di Martino"
                            3 => "P Graziano"
                            4 => "R Giunti"
                            5 => "L Carbone"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.athoracsur.2003.10.089"
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Thorac Surg"
                        "fecha" => "2004"
                        "volumen" => "77"
                        "paginaInicial" => "1781"
                        "paginaFinal" => "1785"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15111186"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib12"
              "etiqueta" => "12"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Large cell neuroendocrine carcinoma of the lung&#58; an aggressive disease potentially treatable with surgery"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "CH Dodoli"
                            1 => "F Barlesi"
                            2 => "B Chetaille"
                            3 => "L Garbe"
                            4 => "P Thomas"
                            5 => "R Giudicelli"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.athoracsur.2003.09.049"
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Thorac Surg"
                        "fecha" => "2004"
                        "volumen" => "77"
                        "paginaInicial" => "1168"
                        "paginaFinal" => "1172"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15063228"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib13"
              "etiqueta" => "13"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Surgical results for small cell lung cancer based on the new TNM staging system"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:8 [
                            0 => "M Inoue"
                            1 => "S Miyoshi"
                            2 => "T Yasumitsu"
                            3 => "T Mori"
                            4 => "K Iuchi"
                            5 => "H Maeda"
                            6 => "al et"
                            7 => "the Thoracic Surgery Study Group of Osaka"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Ann Thorac Surg"
                        "fecha" => "2000"
                        "volumen" => "70"
                        "paginaInicial" => "1615"
                        "paginaFinal" => "1619"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11093496"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0161642008012700"
                          "estado" => "S300"
                          "issn" => "01616420"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib14"
              "etiqueta" => "14"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Large cell neuroendocrine carcinoma and large cell carcinomas with neuroendocrine morphology of the lung&#58; prognosis after complete resection and systematic nodal dissection"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "J Zacharias"
                            1 => "AG Nicholson"
                            2 => "GP Ladas"
                            3 => "P Goldstraw"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Thorac Surg"
                        "fecha" => "2003"
                        "volumen" => "75"
                        "paginaInicial" => "348"
                        "paginaFinal" => "352"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12607637"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib15"
              "etiqueta" => "15"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Large cell neuroendocrine carcinoma of the lung&#58; pathological study and clinical outcome of 18 resected cases"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "J Mazi&#232;res"
                            1 => "GH Daste"
                            2 => "L Molinier"
                            3 => "J Berjaud"
                            4 => "M Dahan"
                            5 => "M Delsol"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Lung Cancer"
                        "fecha" => "2002"
                        "volumen" => "37"
                        "paginaInicial" => "287"
                        "paginaFinal" => "292"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12234698"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib16"
              "etiqueta" => "16"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Large cell neuroendocrine carcinoma of the lung&#58; a 10 year clinicopathologic retrospective study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M Paci"
                            1 => "A Cavazza"
                            2 => "V Annessi"
                            3 => "I Putrino"
                            4 => "G Ferrari"
                            5 => "S de Franco"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.athoracsur.2003.09.070"
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Thorac Surg"
                        "fecha" => "2004"
                        "volumen" => "77"
                        "paginaInicial" => "1163"
                        "paginaFinal" => "1167"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15063227"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib17"
              "etiqueta" => "17"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pulmonary large cell carcinomas with neuroendocrine features are high-grade neuroendocrine tumors"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "A Iyoda"
                            1 => "K Hiroshima"
                            2 => "M Baba"
                            3 => "Y Saitoh"
                            4 => "H Ohwada"
                            5 => "T Fujisawa"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Thorac Surg"
                        "fecha" => "2002"
                        "volumen" => "73"
                        "paginaInicial" => "1049"
                        "paginaFinal" => "1054"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11996239"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib18"
              "etiqueta" => "18"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Large cell neuroendocrine carcinomas of the lung&#58; a clinopathologic study of eighty-seven cases"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "H Takei"
                            1 => "H Asamura"
                            2 => "A Maeshima"
                            3 => "K Suzuki"
                            4 => "H Kondo"
                            5 => "T Niki"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Thorac Cardiovasc Surg"
                        "fecha" => "2002"
                        "volumen" => "124"
                        "paginaInicial" => "285"
                        "paginaFinal" => "292"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12167788"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib19"
              "etiqueta" => "19"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The prognostic role of C-kit protein expression in resected large cell neuroendocrine carcinoma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "CH Casali"
                            1 => "A Stefani"
                            2 => "G Rossi"
                            3 => "M Migaldi"
                            4 => "S Bettelli"
                            5 => "A Parise"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Thorac Surg"
                        "fecha" => "2004"
                        "volumen" => "77"
                        "paginaInicial" => "247"
                        "paginaFinal" => "253"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14726070"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib20"
              "etiqueta" => "20"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Large-cell neuroendocrine carcinoma of the lung&#58; a clinicopathologic study of eighteen cases and the efficacy of adjuvant treatment with octeotride"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "PL Filosso"
                            1 => "E Ruffini"
                            2 => "A Oliaro"
                            3 => "O Rena"
                            4 => "C Casadio"
                            5 => "M Mancuso"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.jtcvs.2004.05.023"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Thorac Cardiovasc Surg"
                        "fecha" => "2005"
                        "volumen" => "129"
                        "paginaInicial" => "819"
                        "paginaFinal" => "824"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15821649"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/15792129/0000004300000010/v1_201305150259/S1579212907601268/v1_201305150259/en/main.assets"
  "Apartado" => null
  "PDF" => "https://static.elsevier.es/multimedia/15792129/0000004300000010/v1_201305150259/S1579212907601268/v1_201305150259/en/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212907601268?idApp=UINPBA00003Z"
]
Share
Journal Information

Statistics

Follow this link to access the full text of the article

Original Articles
Trends in Prognostic Factors for Neuroendocrine Lung Tumors
Mariano García-Yustea,
Corresponding author
mgyuste2@wanadoo.es

Correspondence: Dr. M. García-Yuste. Servicio de Cirugía Torácica. Hospital Clínico Universitario. Ramón y Cajal, 3. 47005 Valladolid. España
, Laureano Molinsb, José M. Matillaa, Federico González-Aragonesesc, Javier López-Pujold, Guillermo Ramosa, Mercedes de la Torree, members of the Spanish Multicenter Study of Neuroendocrine Lung Tumors of the Spanish Society of Pulmonology and Thoracic Surgery (EMETNE-SEPAR) *
a Servicio de Cirugía Torácica, Hospital Clínico Universitario, Valladolid, Spain
b Servicio de Cirugía Torácica, Hospital Sagrado Corazón, Barcelona, Spain
c Servicio de Cirugía Torácica, Hospital Gregorio Marañón, Madrid, Spain
d Servicio de Cirugía Torácica, Hospital Reina Sofía, Córdoba, Spain
e Servicio de Cirugía Torácica, Hospital Juan Canalejo, A Coruña, Spain
Read
4459
Times
was read the article
1726
Total PDF
2733
Total HTML
Share statistics
 array:23 [
  "pii" => "S1579212907601268"
  "issn" => "15792129"
  "doi" => "10.1016/S1579-2129(07)60126-8"
  "estado" => "S300"
  "fechaPublicacion" => "2007-01-01"
  "aid" => "60126"
  "copyright" => "Sociedad Espa&#241;ola de Neumolog&#237;a y Cirug&#237;a Tor&#225;cica &#40;SEPAR&#41;"
  "copyrightAnyo" => "2007"
  "documento" => "article"
  "crossmark" => 0
  "subdocumento" => "fla"
  "cita" => "Arch Bronconeumol. 2007;43:549-56"
  "abierto" => array:3 [
    "ES" => false
    "ES2" => false
    "LATM" => false
  ]
  "gratuito" => false
  "lecturas" => array:2 [
    "total" => 2389
    "formatos" => array:3 [
      "EPUB" => 88
      "HTML" => 1689
      "PDF" => 612
    ]
  ]
  "itemSiguiente" => array:18 [
    "pii" => "S157921290760127X"
    "issn" => "15792129"
    "doi" => "10.1016/S1579-2129(07)60127-X"
    "estado" => "S300"
    "fechaPublicacion" => "2007-01-01"
    "aid" => "60127"
    "copyright" => "Sociedad Espa&#241;ola de Neumolog&#237;a y Cirug&#237;a Tor&#225;cica &#40;SEPAR&#41;"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Arch Bronconeumol. 2007;43:557-61"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 2878
      "formatos" => array:3 [
        "EPUB" => 88
        "HTML" => 1974
        "PDF" => 816
      ]
    ]
    "en" => array:10 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Original Articles</span>"
      "titulo" => "Pulmonary and Nonpulmonary Alterations in Duchenne Muscular Dystrophy"
      "tienePdf" => "en"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "557"
          "paginaFinal" => "561"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Mar&#237;a Rosa G&#252;ell, M&#243;nica Avendano, Janet Fraser, Roger Goldstein"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "Mar&#237;a Rosa"
              "apellidos" => "G&#252;ell"
            ]
            1 => array:2 [
              "nombre" => "M&#243;nica"
              "apellidos" => "Avendano"
            ]
            2 => array:2 [
              "nombre" => "Janet"
              "apellidos" => "Fraser"
            ]
            3 => array:2 [
              "nombre" => "Roger"
              "apellidos" => "Goldstein"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S157921290760127X?idApp=UINPBA00003Z"
    "url" => "/15792129/0000004300000010/v1_201305150259/S157921290760127X/v1_201305150259/en/main.assets"
  ]
  "itemAnterior" => array:18 [
    "pii" => "S1579212907601256"
    "issn" => "15792129"
    "doi" => "10.1016/S1579-2129(07)60125-6"
    "estado" => "S300"
    "fechaPublicacion" => "2007-01-01"
    "aid" => "60125"
    "copyright" => "Sociedad Espa&#241;ola de Neumolog&#237;a y Cirug&#237;a Tor&#225;cica &#40;SEPAR&#41;"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Arch Bronconeumol. 2007;43:542-8"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 2064
      "formatos" => array:3 [
        "EPUB" => 79
        "HTML" => 1336
        "PDF" => 649
      ]
    ]
    "en" => array:10 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Original Articles</span>"
      "titulo" => "Interleukin-8 Expression in Lung Tissue During Ischemia-Reperfusion"
      "tienePdf" => "en"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "542"
          "paginaFinal" => "548"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Jos&#233; Mar&#237;a Matilla, Mariano Garc&#237;a-Yuste, Mariano S&#225;nchez Crespo, Manuel J&#46; Gayoso, F&#233;lix Heras, Marta Jim&#233;nez Prada, Andr&#233;s Alonso, Guillermo Ramos"
          "autores" => array:8 [
            0 => array:2 [
              "nombre" => "Jos&#233; Mar&#237;a"
              "apellidos" => "Matilla"
            ]
            1 => array:2 [
              "nombre" => "Mariano"
              "apellidos" => "Garc&#237;a-Yuste"
            ]
            2 => array:2 [
              "nombre" => "Mariano S&#225;nchez"
              "apellidos" => "Crespo"
            ]
            3 => array:2 [
              "nombre" => "Manuel J&#46;"
              "apellidos" => "Gayoso"
            ]
            4 => array:2 [
              "nombre" => "F&#233;lix"
              "apellidos" => "Heras"
            ]
            5 => array:2 [
              "nombre" => "Marta Jim&#233;nez"
              "apellidos" => "Prada"
            ]
            6 => array:2 [
              "nombre" => "Andr&#233;s"
              "apellidos" => "Alonso"
            ]
            7 => array:2 [
              "nombre" => "Guillermo"
              "apellidos" => "Ramos"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212907601256?idApp=UINPBA00003Z"
    "url" => "/15792129/0000004300000010/v1_201305150259/S1579212907601256/v1_201305150259/en/main.assets"
  ]
  "en" => array:15 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Original Articles</span>"
    "titulo" => "Trends in Prognostic Factors for Neuroendocrine Lung Tumors"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "549"
        "paginaFinal" => "556"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "Mariano Garc&#237;a-Yuste, Laureano Molins, Jos&#233; M&#46; Matilla, Federico Gonz&#225;lez-Aragoneses, Javier L&#243;pez-Pujol, Guillermo Ramos, Mercedes de la Torre"
        "autores" => array:8 [
          0 => array:4 [
            "nombre" => "Mariano"
            "apellidos" => "Garc&#237;a-Yuste"
            "email" => array:1 [
              0 => "mgyuste2&#64;wanadoo&#46;es"
            ]
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff1"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor1"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "Laureano"
            "apellidos" => "Molins"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff2"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "Jos&#233; M&#46;"
            "apellidos" => "Matilla"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff1"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "Federico"
            "apellidos" => "Gonz&#225;lez-Aragoneses"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">c</span>"
                "identificador" => "aff3"
              ]
            ]
          ]
          4 => array:3 [
            "nombre" => "Javier"
            "apellidos" => "L&#243;pez-Pujol"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">d</span>"
                "identificador" => "aff4"
              ]
            ]
          ]
          5 => array:3 [
            "nombre" => "Guillermo"
            "apellidos" => "Ramos"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff1"
              ]
            ]
          ]
          6 => array:3 [
            "nombre" => "Mercedes"
            "apellidos" => "de la Torre"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">e</span>"
                "identificador" => "aff5"
              ]
            ]
          ]
          7 => array:2 [
            "colaborador" => "members of the Spanish Multicenter Study of Neuroendocrine Lung Tumors of the Spanish Society of Pulmonology and Thoracic Surgery &#40;EMETNE-SEPAR&#41;"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "fn1"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:5 [
          0 => array:3 [
            "entidad" => "Servicio de Cirug&#237;a Tor&#225;cica&#44; Hospital Cl&#237;nico Universitario&#44; Valladolid&#44; Spain"
            "etiqueta" => "<span class="elsevierStyleSup">a</span>"
            "identificador" => "aff1"
          ]
          1 => array:3 [
            "entidad" => "Servicio de Cirug&#237;a Tor&#225;cica&#44; Hospital Sagrado Coraz&#243;n&#44; Barcelona&#44; Spain"
            "etiqueta" => "<span class="elsevierStyleSup">b</span>"
            "identificador" => "aff2"
          ]
          2 => array:3 [
            "entidad" => "Servicio de Cirug&#237;a Tor&#225;cica&#44; Hospital Gregorio Mara&#241;&#243;n&#44; Madrid&#44; Spain"
            "etiqueta" => "<span class="elsevierStyleSup">c</span>"
            "identificador" => "aff3"
          ]
          3 => array:3 [
            "entidad" => "Servicio de Cirug&#237;a Tor&#225;cica&#44; Hospital Reina Sof&#237;a&#44; C&#243;rdoba&#44; Spain"
            "etiqueta" => "<span class="elsevierStyleSup">d</span>"
            "identificador" => "aff4"
          ]
          4 => array:3 [
            "entidad" => "Servicio de Cirug&#237;a Tor&#225;cica&#44; Hospital Juan Canalejo&#44; A Coru&#241;a&#44; Spain"
            "etiqueta" => "<span class="elsevierStyleSup">e</span>"
            "identificador" => "aff5"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor1"
            "etiqueta" => "&#42;"
            "correspondencia" => "Correspondence&#58; Dr&#46; M&#46; Garc&#237;a-Yuste&#46; Servicio de Cirug&#237;a Tor&#225;cica&#46; Hospital Cl&#237;nico Universitario&#46; Ram&#243;n y Cajal&#44; 3&#46; 47005 Valladolid&#46; Espa&#241;a"
          ]
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2006-10-05"
    "fechaAceptado" => "2007-11-22"
    "PalabrasClave" => array:2 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Key words"
          "identificador" => "xpalclavsec154626"
          "palabras" => array:3 [
            0 => "Neuroendocrine lung tumor"
            1 => "Staging"
            2 => "Mediastinal lymph node excision"
          ]
        ]
      ]
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec154625"
          "palabras" => array:3 [
            0 => "Tumor pulmonar neuroendocrino"
            1 => "Estadificaci&#243;n"
            2 => "Disecci&#243;n ganglionar mediast&#237;nica"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "en" => array:1 [
        "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">The aim of this study was to analyze trends in a variety of prognostic factors for neuroendocrine lung carcinomas through analysis of 2 groups of surgically treated patients&#46;</p> <span class="elsevierStyleSectionTitle">PATIENTS AND METHODS</span><p class="elsevierStyleSimplePara elsevierViewall">Group A contained the first 361 patients&#44; treated between 1980 and 1997&#46; That group was analyzed retrospectively and contained 261 patients with typical carcinoid tumors&#44; 43 with atypical carcinoid tumors&#44; 22 with large-cell neuroendocrine carcinoma&#44; and 35 with small-cell neuroendocrine carcinoma&#46; Group B contained 404 patients enrolled prospectively between 1998 and 2002&#58; 308 with typical carcinoid tumors&#44; 49 with atypical carcinoid tumors&#44; 18 with large-cell neuroendocrine carcinoma&#44; and 29 with small-cell neuroendocrine carcinoma&#46; The following clinical variables were considered&#58; sex&#44; mean age&#44; tumor site&#44; tumor size&#44; lymph node involvement&#44; stage&#44; metastasis&#44; and local recurrence&#46; The 1997 TNM classification was used for staging of lung cancer and survival analysis was performed along with assessment of factors influencing survival&#46; Statistical analysis of the data involved univariate and multivariate analysis&#46;</p> <span class="elsevierStyleSectionTitle">RESULTS</span><p class="elsevierStyleSimplePara elsevierViewall">In both groups&#44; significant differences were observed between patients with typical and atypical carcinoid tumors in terms of mean age&#44; tumor size&#44; node involvement&#44; and recurrence&#46; In group A&#44; female sex&#44; node involvement&#44; and recurrence differed between patients with atypical carcinoid tumors and those with large-cell neuroendocrine carcinoma&#59; the same was true for group B&#44; with the exception of lymph node involvement&#46; Node involvement differed between patients with small-cell versus large-cell neuroendocrine carcinoma in group A but not group B&#46;</p><p class="elsevierStyleSimplePara elsevierViewall">Both groups displayed significant differences in overall survival and survival of patients with lymph node involvement between patients with typical and atypical carcinoid tumors and between patients with atypical carcinoid tumors and those with large- cell neuroendocrine carcinoma&#59; no differences were observed between patients with large-cell versus small-cell neuroendocrine carcinoma&#46; Histological type and lymph node involvement had the greatest influence on prognosis in the multivariate analysis&#46;</p> <span class="elsevierStyleSectionTitle">CONCLUSIONS</span><p class="elsevierStyleSimplePara elsevierViewall">A well-defined trend is observed in prognostic factors for neuroendocrine lung tumors&#46; Histological type and lymph node involvement show the greatest influence on survival&#46;</p>"
      ]
      "es" => array:1 [
        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">Este estudio tiene como objetivo determinar la tendencia de distintos factores pron&#243;sticos en carcinomas neuroendocrinos del pulm&#243;n a trav&#233;s del an&#225;lisis de 2 grupos de pacientes tratados quir&#250;rgicamente&#46;</p> <span class="elsevierStyleSectionTitle">PACIENTES Y M&#201;TODOS</span><p class="elsevierStyleSimplePara elsevierViewall">En el grupo A se incluyeron los primeros 361 casos&#44; tratados entre 1980 y 1997 &#8212;261 carcinoides t&#237;picos &#40;CT&#41;&#44; 43 carcinoides at&#237;picos &#40;CA&#41;&#44; 22 carcinomas neuroendocrinos de c&#233;lulas grandes &#40;CNECG&#41; y 35 carcinomas neuroendocrinos de c&#233;lulas peque&#241;as &#40;CNECP&#41;&#8212;&#44; que se estudiaron retrospectivamente&#46; El grupo B estuvo compuesto por 404 casos&#44; recogidos desde 1998 a 2002 &#8212;308 CT&#44; 49 CA&#44; 18 CNECG y 29 CNECP&#8212;&#44; que se estudiaron prospectivamente&#46; Las variables cl&#237;nicas consideradas fueron&#58; sexo&#44; edad media&#44; localizaci&#243;n tumoral&#44; tama&#241;o tumoral&#44; afectaci&#243;n ganglionar&#44; estadio&#44; met&#225;stasis y recurrencia local&#46; Se utiliz&#243; la clasificaci&#243;n TNM del carcinoma broncog&#233;nico de 1997 y se practic&#243; un estudio de supervivencia y de factores que influyen en ella&#46; Se realiz&#243; un an&#225;lisis estad&#237;stico uni y multivariante con los datos obtenidos&#46;</p> <span class="elsevierStyleSectionTitle">RESULTADOS</span><p class="elsevierStyleSimplePara elsevierViewall">Por lo que se refiere al CT y al CA&#44; se observaron diferencias significativas en los 2 grupos de pacientes en cuanto a la edad media&#44; el tama&#241;o tumoral&#44; la afectaci&#243;n ganglionar y la recurrencia&#46; Entre CA y CNECG&#44; el sexo&#44; la afectaci&#243;n ganglionar y la recurrencia difirieron en el grupo A&#59; lo mismo ocurri&#243; en el grupo B&#44; con la excepci&#243;n de la afectaci&#243;n ganglionar&#46; Entre CNECG y CNECP&#44; la diferencia en la afectaci&#243;n ganglionar observada en el grupo A no estuvo presente en los pacientes del grupo B&#46; Respecto a la supervivencia&#44; global y por afectaci&#243;n ganglionar&#44; se observaron diferencias significativas en ambos grupos al comparar CT frente a CA y CA frente a CNECG&#59; no se encontraron diferencias entre CNECG y CNECP&#46; El tipo histol&#243;gico y la afectaci&#243;n ganglionar mostraron la mayor influencia pron&#243;stica en an&#225;lisis multivariante&#46;</p> <span class="elsevierStyleSectionTitle">CONCLUSIONES</span><p class="elsevierStyleSimplePara elsevierViewall">En los carcinomas neuroendocrinos de pulm&#243;n se observa una tendencia definida en sus factores pron&#243;sticos&#46; El tipo histol&#243;gico y la detecci&#243;n de afectaci&#243;n ganglionar se muestran como los factores con mayor influencia en la supervivencia&#46;</p>"
      ]
    ]
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#42;"
        "nota" => "<p class="elsevierStyleNotepara">The names of the EMETNE-SEPAR members are provided at the end of the article&#46;</p>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "REFERENCES"
      "seccion" => array:1 [
        0 => array:1 [
          "bibliografiaReferencia" => array:20 [
            0 => array:3 [
              "identificador" => "bib1"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Survival analysis of 200 pulmonary neuroendocrine tumors with clarification of criteria for atypical carcinoid and its separation from typical carcinoid"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "WD Travis"
                            1 => "W Rush"
                            2 => "DB Flieder"
                            3 => "R Falk"
                            4 => "M Fleming"
                            5 => "A Gal"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Surg Pathol"
                        "fecha" => "1998"
                        "volumen" => "22"
                        "paginaInicial" => "934"
                        "paginaFinal" => "944"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9706973"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib2"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Bronchial carcinoid tumors&#58; surgical management and longterm outcome"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "PL Filosso"
                            1 => "O Rena"
                            2 => "G Donati"
                            3 => "C Casadio"
                            4 => "E Ruffini"
                            5 => "E Papalia"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Thorac Cardiovasc Surg"
                        "fecha" => "2002"
                        "volumen" => "123"
                        "paginaInicial" => "303"
                        "paginaFinal" => "309"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11828290"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib3"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Assessment of outcomes in typical and atypical carcinoids according to latest WHO classification"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M Mezzetti"
                            1 => "F Raveglia"
                            2 => "T Panigalli"
                            3 => "L Giuliani"
                            4 => "F lo Giudice"
                            5 => "S Meda"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Thorac Surg"
                        "fecha" => "2003"
                        "volumen" => "76"
                        "paginaInicial" => "1838"
                        "paginaFinal" => "1842"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14667595"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib4"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Neuroendocrine tumors of the bronchopulmonary tract&#46; A reappraisal of their classification after 20 years"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "WH Warren"
                            1 => "VE Gould"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Surg Clin N Am"
                        "fecha" => "2002"
                        "volumen" => "82"
                        "paginaInicial" => "525"
                        "paginaFinal" => "540"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12371583"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib5"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prognostic factors in neuroendocrine lung tumors&#58; a Spanish multicenter study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:7 [
                            0 => "M Garc&#237;a-Yuste"
                            1 => "JM Matilla"
                            2 => "T &#193;lvarez Gago"
                            3 => "JL Duque"
                            4 => "F Heras"
                            5 => "LJ Cerezal"
                            6 => "the Spanish Multicenter Study of Neuroendocrine Tumors of the Lung &#40;EMETNE-SEPAR&#41;"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Thorac Surg"
                        "fecha" => "2000"
                        "volumen" => "70"
                        "paginaInicial" => "258"
                        "paginaFinal" => "263"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10921719"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib6"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Small cell lung cancer&#58; how should be treated it&#63; What is it&#63;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "RJ Ginsberg"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Thorac Surg"
                        "fecha" => "2000"
                        "volumen" => "70"
                        "paginaInicial" => "1453"
                        "paginaFinal" => "1454"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11093468"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib7"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:1 [
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "WD Travis"
                            1 => "LH Sobin"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:4 [
                        "titulo" => "Histologic typing of lung and pleural tumours&#59; International Histologic Classification of Tumours"
                        "fecha" => "1999"
                        "editorial" => "Springer-Verlag"
                        "editorialLocalizacion" => "New York"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib8"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Clinical-pathologic analysis of 40 patients with large cell neuroendocrine carcinoma of the lung"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "CM Dresler"
                            1 => "JH Ritter"
                            2 => "GA Patterson"
                            3 => "E Ross"
                            4 => "MS Biley"
                            5 => "MR Wick"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Thorac Surg"
                        "fecha" => "1997"
                        "volumen" => "63"
                        "paginaInicial" => "180"
                        "paginaFinal" => "185"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8993262"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib9"
              "etiqueta" => "9"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Revisions in the international system for staging lung cancer"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "CF Mountain"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "1997"
                        "volumen" => "111"
                        "paginaInicial" => "1710"
                        "paginaFinal" => "1717"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9187198"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib10"
              "etiqueta" => "10"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Typical and atypical pulmonary carcinoids&#46; Outcome in patients presenting with regional limph node involvement"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "CHF Thomas"
                            1 => "HD Tazelaar"
                            2 => "JR Jett"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Chest"
                        "fecha" => "2001"
                        "volumen" => "119"
                        "paginaInicial" => "1143"
                        "paginaFinal" => "1150"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11296182"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib11"
              "etiqueta" => "11"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Bronchial carcinoid tumors&#58; nodal status and long-term survival after resection"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "G Cardillo"
                            1 => "F Sera"
                            2 => "M Di Martino"
                            3 => "P Graziano"
                            4 => "R Giunti"
                            5 => "L Carbone"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.athoracsur.2003.10.089"
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Thorac Surg"
                        "fecha" => "2004"
                        "volumen" => "77"
                        "paginaInicial" => "1781"
                        "paginaFinal" => "1785"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15111186"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib12"
              "etiqueta" => "12"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Large cell neuroendocrine carcinoma of the lung&#58; an aggressive disease potentially treatable with surgery"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "CH Dodoli"
                            1 => "F Barlesi"
                            2 => "B Chetaille"
                            3 => "L Garbe"
                            4 => "P Thomas"
                            5 => "R Giudicelli"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.athoracsur.2003.09.049"
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Thorac Surg"
                        "fecha" => "2004"
                        "volumen" => "77"
                        "paginaInicial" => "1168"
                        "paginaFinal" => "1172"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15063228"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib13"
              "etiqueta" => "13"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Surgical results for small cell lung cancer based on the new TNM staging system"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:8 [
                            0 => "M Inoue"
                            1 => "S Miyoshi"
                            2 => "T Yasumitsu"
                            3 => "T Mori"
                            4 => "K Iuchi"
                            5 => "H Maeda"
                            6 => "al et"
                            7 => "the Thoracic Surgery Study Group of Osaka"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Ann Thorac Surg"
                        "fecha" => "2000"
                        "volumen" => "70"
                        "paginaInicial" => "1615"
                        "paginaFinal" => "1619"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11093496"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0161642008012700"
                          "estado" => "S300"
                          "issn" => "01616420"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib14"
              "etiqueta" => "14"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Large cell neuroendocrine carcinoma and large cell carcinomas with neuroendocrine morphology of the lung&#58; prognosis after complete resection and systematic nodal dissection"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "J Zacharias"
                            1 => "AG Nicholson"
                            2 => "GP Ladas"
                            3 => "P Goldstraw"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Thorac Surg"
                        "fecha" => "2003"
                        "volumen" => "75"
                        "paginaInicial" => "348"
                        "paginaFinal" => "352"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12607637"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib15"
              "etiqueta" => "15"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Large cell neuroendocrine carcinoma of the lung&#58; pathological study and clinical outcome of 18 resected cases"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "J Mazi&#232;res"
                            1 => "GH Daste"
                            2 => "L Molinier"
                            3 => "J Berjaud"
                            4 => "M Dahan"
                            5 => "M Delsol"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Lung Cancer"
                        "fecha" => "2002"
                        "volumen" => "37"
                        "paginaInicial" => "287"
                        "paginaFinal" => "292"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12234698"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib16"
              "etiqueta" => "16"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Large cell neuroendocrine carcinoma of the lung&#58; a 10 year clinicopathologic retrospective study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M Paci"
                            1 => "A Cavazza"
                            2 => "V Annessi"
                            3 => "I Putrino"
                            4 => "G Ferrari"
                            5 => "S de Franco"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.athoracsur.2003.09.070"
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Thorac Surg"
                        "fecha" => "2004"
                        "volumen" => "77"
                        "paginaInicial" => "1163"
                        "paginaFinal" => "1167"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15063227"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib17"
              "etiqueta" => "17"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pulmonary large cell carcinomas with neuroendocrine features are high-grade neuroendocrine tumors"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "A Iyoda"
                            1 => "K Hiroshima"
                            2 => "M Baba"
                            3 => "Y Saitoh"
                            4 => "H Ohwada"
                            5 => "T Fujisawa"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Thorac Surg"
                        "fecha" => "2002"
                        "volumen" => "73"
                        "paginaInicial" => "1049"
                        "paginaFinal" => "1054"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11996239"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib18"
              "etiqueta" => "18"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Large cell neuroendocrine carcinomas of the lung&#58; a clinopathologic study of eighty-seven cases"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "H Takei"
                            1 => "H Asamura"
                            2 => "A Maeshima"
                            3 => "K Suzuki"
                            4 => "H Kondo"
                            5 => "T Niki"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Thorac Cardiovasc Surg"
                        "fecha" => "2002"
                        "volumen" => "124"
                        "paginaInicial" => "285"
                        "paginaFinal" => "292"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12167788"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib19"
              "etiqueta" => "19"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The prognostic role of C-kit protein expression in resected large cell neuroendocrine carcinoma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "CH Casali"
                            1 => "A Stefani"
                            2 => "G Rossi"
                            3 => "M Migaldi"
                            4 => "S Bettelli"
                            5 => "A Parise"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Thorac Surg"
                        "fecha" => "2004"
                        "volumen" => "77"
                        "paginaInicial" => "247"
                        "paginaFinal" => "253"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14726070"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib20"
              "etiqueta" => "20"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Large-cell neuroendocrine carcinoma of the lung&#58; a clinicopathologic study of eighteen cases and the efficacy of adjuvant treatment with octeotride"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "PL Filosso"
                            1 => "E Ruffini"
                            2 => "A Oliaro"
                            3 => "O Rena"
                            4 => "C Casadio"
                            5 => "M Mancuso"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.jtcvs.2004.05.023"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Thorac Cardiovasc Surg"
                        "fecha" => "2005"
                        "volumen" => "129"
                        "paginaInicial" => "819"
                        "paginaFinal" => "824"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15821649"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/15792129/0000004300000010/v1_201305150259/S1579212907601268/v1_201305150259/en/main.assets"
  "Apartado" => null
  "PDF" => "https://static.elsevier.es/multimedia/15792129/0000004300000010/v1_201305150259/S1579212907601268/v1_201305150259/en/main.pdf?idApp=UINPBA00003Z&text.app=https://archbronconeumol.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212907601268?idApp=UINPBA00003Z"
]
Article information
ISSN: 15792129
Original language: English
The statistics are updated each day
Year/Month Html Pdf Total
2024 November 3 3 6
2024 October 30 24 54
2024 September 28 14 42
2024 August 52 38 90
2024 July 23 20 43
2024 June 27 23 50
2024 May 38 21 59
2024 April 18 30 48
2024 March 20 14 34
2024 February 19 17 36
2023 March 1 0 1
2023 February 14 21 35
2023 January 18 30 48
2022 December 26 34 60
2022 November 13 19 32
2022 October 22 23 45
2022 September 22 26 48
2022 August 17 29 46
2022 July 24 41 65
2022 June 20 33 53
2022 May 14 31 45
2022 April 19 26 45
2022 March 20 39 59
2022 February 13 21 34
2022 January 21 36 57
2021 December 54 57 111
2021 November 26 42 68
2021 October 35 44 79
2021 September 14 62 76
2021 August 24 29 53
2021 July 50 26 76
2021 June 13 19 32
2021 May 17 29 46
2021 April 15 36 51
2021 March 21 17 38
2021 February 15 11 26
2021 January 14 19 33
2020 December 12 13 25
2020 November 10 10 20
2020 October 11 12 23
2020 September 8 0 8
2020 August 40 6 46
2020 July 30 24 54
2020 June 18 1 19
2020 May 34 13 47
2020 April 47 13 60
2020 March 8 15 23
2020 February 14 8 22
2020 January 50 15 65
2019 December 22 11 33
2019 November 13 7 20
2019 October 3 4 7
2019 September 4 10 14
2019 August 8 4 12
2019 July 13 16 29
2019 June 5 7 12
2019 May 6 8 14
2019 April 15 24 39
2019 March 3 16 19
2019 February 6 10 16
2019 January 5 7 12
2018 December 6 15 21
2018 November 10 17 27
2018 October 25 24 49
2018 September 9 6 15
2018 May 4 0 4
2018 April 7 7 14
2018 March 7 3 10
2018 February 4 8 12
2018 January 4 5 9
2017 December 2 6 8
2017 November 3 4 7
2017 October 4 7 11
2017 September 4 10 14
2017 August 6 9 15
2017 July 4 9 13
2017 June 10 12 22
2017 May 4 4 8
2017 April 4 5 9
2017 March 1 4 5
2017 February 1 2 3
2017 January 1 1 2
2016 December 2 6 8
2016 November 5 6 11
2016 October 6 5 11
2016 September 4 1 5
2016 August 6 4 10
2016 July 1 3 4
2016 March 1 0 1
2016 February 1 0 1
2015 December 2 0 2
2015 October 46 17 63
2015 September 62 11 73
2015 August 42 19 61
2015 July 55 10 65
2015 June 40 7 47
2015 May 48 16 64
2015 April 31 13 44
2015 March 46 3 49
2015 February 28 5 33
2015 January 31 4 35
2014 December 47 7 54
2014 November 52 6 58
2014 October 64 8 72
2014 September 38 12 50
2014 August 45 11 56
2014 July 41 6 47
2014 June 46 12 58
2014 May 48 14 62
2014 April 46 4 50
2014 March 49 13 62
2014 February 43 7 50
2014 January 48 9 57
2013 December 46 11 57
2013 November 50 2 52
2013 October 44 9 53
2013 September 47 13 60
2013 August 39 5 44
2013 July 57 14 71
2013 June 28 5 33
2013 May 44 5 49
2013 April 21 6 27
2013 March 8 1 9
Show all

Follow this link to access the full text of the article

Archivos de Bronconeumología

Are you a health professional able to prescribe or dispense drugs?