Correspondence: Dra. C. Lisboa. Departamento de Enfermedades Respiratorias. Pontificia Universidad Católica de Chile. Marcoleta, 352, piso 1. Santiago. Chile
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"aid" => "60111" "copyright" => "Sociedad Española de Neumología y Cirugía Torácica (SEPAR)" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Arch Bronconeumol. 2007;43:479-84" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 3653 "formatos" => array:3 [ "EPUB" => 87 "HTML" => 2924 "PDF" => 642 ] ] "en" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Original Articles</span>" "titulo" => "Expression of Proteins Associated With Multidrug Resistance to Chemotherapy in Lung Cancer" "tienePdf" => "en" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "479" "paginaFinal" => "484" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Alfredo Paredes Lario, Carlos Blanco García, Miguel Echenique Elizondo, Carmen Lobo" "autores" => array:4 [ 0 => array:2 [ "nombre" => "Alfredo Paredes" "apellidos" => "Lario" ] 1 => array:2 [ "nombre" => "Carlos Blanco" "apellidos" => "García" ] 2 => array:2 [ "nombre" => "Miguel Echenique" "apellidos" => "Elizondo" ] 3 => array:2 [ "nombre" => "Carmen" "apellidos" => "Lobo" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212907601116?idApp=UINPBA00003Z" "url" => "/15792129/0000004300000009/v1_201305150327/S1579212907601116/v1_201305150327/en/main.assets" ] "en" => array:15 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Original Articles</span>" "titulo" => "Reference Values for Inspiratory Capacity in Healthy Nonsmokers Over Age 50 Years" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "485" "paginaFinal" => "489" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Carmen Lisboa, Alicia Leiva, Ramón Pinochet, Paula Repetto, Gisella Borzone, Orlando Díaz" "autores" => array:6 [ 0 => array:4 [ "nombre" => "Carmen" "apellidos" => "Lisboa" "email" => array:1 [ 0 => "clisboa@med.puc.cl" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor1" ] ] ] 1 => array:2 [ "nombre" => "Alicia" "apellidos" => "Leiva" ] 2 => array:2 [ "nombre" => "Ramón" "apellidos" => "Pinochet" ] 3 => array:2 [ "nombre" => "Paula" "apellidos" => "Repetto" ] 4 => array:2 [ "nombre" => "Gisella" "apellidos" => "Borzone" ] 5 => array:2 [ "nombre" => "Orlando" "apellidos" => "Díaz" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Departamento de Enfermedades Respiratorias, Facultad de Medicina y Escuela de Psicología, Pontificia Universidad Católica de Chile, Santiago, Chile" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "*" "correspondencia" => "Correspondence: Dra. C. Lisboa. Departamento de Enfermedades Respiratorias. Pontificia Universidad Católica de Chile. Marcoleta, 352, piso 1. Santiago. Chile" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2006-05-31" "fechaAceptado" => "2007-04-03" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec154986" "palabras" => array:3 [ 0 => "Inspiratory capacity" 1 => "Reference values" 2 => "Slow vital capacity" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec154987" "palabras" => array:3 [ 0 => "Capacidad inspiratoria" 1 => "Valores de referencia" 2 => "Capacidad vital lenta" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">The role of dynamic hyperinflation in triggering dyspnea and limiting exercise capacity in patients with chronic obstructive pulmonary disease has been recognized in recent years. The degree of dynamic hyperinflation can be assessed by measuring reduction in inspiratory capacity (IC). The aim of this study was to establish reference values for IC in healthy individuals of both sexes between the ages of 50 and 87 years, as such data are scarce in the literature.</p> <span class="elsevierStyleSectionTitle">Subjects and methods</span><p class="elsevierStyleSimplePara elsevierViewall">We studied 155 healthy volunteers (93 women) with normal spirometry. None had a prior history of respiratory, cardiovascular, or systemic diseases that might alter lung function. All were never-smokers. IC was measured during a normal, unforced inspiration to total lung capacity starting from functional residual capacity. The highest value of 6 satisfactory maneuvers was recorded. Sex, height, age, and weight were included in the regression equations. One thousand bootstrap samples for each sex were also analyzed.</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">For each sex, we found that a model including age, height, and weight produced IC prediction equations with a coefficient of determination (<span class="elsevierStyleItalic">r</span><span class="elsevierStyleSup">2</span>) of 0.414 for women and 0.447 for men. The mean (SD) intrasubject coefficient of variation was 4.3% (2%) for IC measured during a single session and 5.1% (0.4%) for measurements from 5 weekly sessions.</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">Our results provide reference equations for IC that are valid for a healthy population over 50 years of age. Predicted values were similar to those recently obtained in an Italian population aged between 65 and 85 years.</p>" ] "es" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">En los últimos años se ha reconocido la importancia de la hiperinflación dinámica en la génesis de la disnea y de la limitación al ejercicio en la enfermedad pulmonar obstructiva crónica (EPOC), y que su magnitud puede evaluarse a través de la reducción de la capacidad inspiratoria (CI). Nuestro objetivo ha sido establecer valores de referencia de la CI en individuos sanos de ambos sexos, de entre 50 y 87 años de edad, debido a que en la literatura médica disponible prácticamente no se ofrecen tales datos.</p> <span class="elsevierStyleSectionTitle">Sujetos y métodos</span><p class="elsevierStyleSimplePara elsevierViewall">Estudiamos a 155 voluntarios sanos (93 mujeres), que nunca habían fumado ni presentaban antecedentes de enfermedades respiratorias, cardiovasculares o sistémicas que pudieran alterar la función pulmonar, y cuya espirometría era normal. La CI se midió durante una inspiración no forzada hasta la capacidad pulmonar total a partir del valor en reposo espiratorio, y para los resultados se empleó el valor más alto de 6 maniobras satisfactorias. En las ecuaciones de regresión se incluyeron el sexo, la talla, la edad y el peso. Se empleó además el método de <span class="elsevierStyleItalic">bootstrapping</span> de 1.000 muestras para cada sexo como procedimiento de análisis.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Encontramos para cada sexo que un mode-lo que incorporó la edad, la talla y el peso produjo ecuaciones predictivas de CI con un coeficiente de determinación r2 = 0,414 y 0,447 para mujeres y varones, respectivamente. El coeficiente de variación intrasujeto en una misma sesión fue (media ± desviación estándar) del 4,3 ± 2%, y en 5 sesiones separadas por una semana fue del 5,1 ± 0,4%.</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">Nuestros resultados proporcionan ecuaciones de referencia para CI válidas en población sana mayor de 50 años. Los valores predichos son semejantes a los recientemente obtenidos en población italiana de 65-85 años de edad.</p>" ] ] "NotaPie" => array:1 [ 0 => array:1 [ "nota" => "<p class="elsevierStyleNotepara">This study was funded by the Fondecyt Project (1010993).</p>" ] ] "bibliografia" => array:2 [ "titulo" => "REFERENCES" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:26 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Exertional breathlessness in patients with chronic airflow limitation: the role of lung hyperinflation" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "DE O'Donnell" 1 => "KA Webb" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/ajrccm/148.5.1351" "Revista" => array:6 [ "tituloSerie" => "Am Rev Respir Dis" "fecha" => "1993" "volumen" => "148" "paginaInicial" => "1351" "paginaFinal" => "1357" 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Year/Month | Html | Total | |
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2024 November | 5 | 3 | 8 |
2024 October | 35 | 13 | 48 |
2024 September | 37 | 12 | 49 |
2024 August | 49 | 36 | 85 |
2024 July | 21 | 21 | 42 |
2024 June | 41 | 35 | 76 |
2024 May | 35 | 30 | 65 |
2024 April | 53 | 27 | 80 |
2024 March | 25 | 29 | 54 |
2024 February | 26 | 23 | 49 |
2023 October | 0 | 2 | 2 |
2023 March | 4 | 4 | 8 |
2023 February | 18 | 12 | 30 |
2023 January | 18 | 34 | 52 |
2022 December | 17 | 32 | 49 |
2022 November | 19 | 23 | 42 |
2022 October | 21 | 28 | 49 |
2022 September | 17 | 27 | 44 |
2022 August | 21 | 34 | 55 |
2022 July | 22 | 34 | 56 |
2022 June | 14 | 29 | 43 |
2022 May | 23 | 28 | 51 |
2022 April | 20 | 20 | 40 |
2022 March | 14 | 39 | 53 |
2022 February | 15 | 36 | 51 |
2022 January | 18 | 26 | 44 |
2021 December | 12 | 41 | 53 |
2021 November | 17 | 52 | 69 |
2021 October | 19 | 39 | 58 |
2021 September | 15 | 68 | 83 |
2021 August | 14 | 32 | 46 |
2021 July | 8 | 30 | 38 |
2021 June | 16 | 32 | 48 |
2021 May | 13 | 29 | 42 |
2021 April | 24 | 45 | 69 |
2021 March | 30 | 16 | 46 |
2021 February | 10 | 14 | 24 |
2021 January | 13 | 23 | 36 |
2020 December | 7 | 14 | 21 |
2020 November | 11 | 14 | 25 |
2020 October | 6 | 8 | 14 |
2020 September | 7 | 6 | 13 |
2020 August | 12 | 11 | 23 |
2020 July | 9 | 16 | 25 |
2020 June | 26 | 2 | 28 |
2020 May | 17 | 10 | 27 |
2020 April | 12 | 18 | 30 |
2020 March | 8 | 12 | 20 |
2020 February | 17 | 17 | 34 |
2020 January | 7 | 20 | 27 |
2019 December | 27 | 13 | 40 |
2019 November | 9 | 11 | 20 |
2019 October | 7 | 13 | 20 |
2019 September | 17 | 26 | 43 |
2019 August | 7 | 12 | 19 |
2019 July | 10 | 22 | 32 |
2019 June | 6 | 19 | 25 |
2019 May | 9 | 26 | 35 |
2019 April | 10 | 34 | 44 |
2019 March | 9 | 19 | 28 |
2019 February | 5 | 13 | 18 |
2019 January | 7 | 13 | 20 |
2018 December | 6 | 19 | 25 |
2018 November | 15 | 18 | 33 |
2018 October | 14 | 35 | 49 |
2018 September | 13 | 15 | 28 |
2018 May | 4 | 3 | 7 |
2018 April | 10 | 29 | 39 |
2018 March | 3 | 30 | 33 |
2018 February | 5 | 20 | 25 |
2018 January | 4 | 25 | 29 |
2017 December | 9 | 25 | 34 |
2017 November | 3 | 17 | 20 |
2017 October | 4 | 17 | 21 |
2017 September | 7 | 13 | 20 |
2017 August | 5 | 20 | 25 |
2017 July | 3 | 8 | 11 |
2017 June | 8 | 17 | 25 |
2017 May | 11 | 16 | 27 |
2017 April | 3 | 9 | 12 |
2017 March | 3 | 22 | 25 |
2017 February | 0 | 6 | 6 |
2017 January | 2 | 7 | 9 |
2016 December | 6 | 6 | 12 |
2016 November | 11 | 7 | 18 |
2016 October | 12 | 15 | 27 |
2016 September | 13 | 13 | 26 |
2016 August | 11 | 5 | 16 |
2016 July | 4 | 0 | 4 |
2016 March | 2 | 0 | 2 |
2015 December | 2 | 0 | 2 |
2015 October | 154 | 21 | 175 |
2015 September | 125 | 10 | 135 |
2015 August | 117 | 17 | 134 |
2015 July | 168 | 15 | 183 |
2015 June | 135 | 10 | 145 |
2015 May | 122 | 14 | 136 |
2015 April | 135 | 8 | 143 |
2015 March | 151 | 10 | 161 |
2015 February | 160 | 5 | 165 |
2015 January | 126 | 9 | 135 |
2014 December | 173 | 9 | 182 |
2014 November | 192 | 6 | 198 |
2014 October | 238 | 11 | 249 |
2014 September | 134 | 13 | 147 |
2014 August | 124 | 11 | 135 |
2014 July | 112 | 6 | 118 |
2014 June | 162 | 7 | 169 |
2014 May | 179 | 10 | 189 |
2014 April | 201 | 5 | 206 |
2014 March | 180 | 14 | 194 |
2014 February | 110 | 8 | 118 |
2014 January | 86 | 17 | 103 |
2013 December | 69 | 13 | 82 |
2013 November | 74 | 10 | 84 |
2013 October | 68 | 19 | 87 |
2013 September | 89 | 13 | 102 |
2013 August | 90 | 12 | 102 |
2013 July | 66 | 13 | 79 |
2013 June | 52 | 13 | 65 |
2013 May | 57 | 5 | 62 |
2013 April | 25 | 13 | 38 |
2013 March | 10 | 1 | 11 |