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        "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">Recent recognition of the importance of nonpulmonary signs and symptoms in the management and prognosis of chronic obstructive pulmonary disease &#40;COPD&#41; has led to a shift in the focus of diagnostic and therapeutic strategies to encompass these aspects&#46; We no longer concentrate on assessing a single functional variable &#40;forced expiratory volume in 1 second&#41; as a predictor of survival in these patients&#46; Most of the research undertaken to date into COPD-related systemic disorders has targeted weight loss&#44; muscular dysfunction&#44; osteoporosis&#44; and cardiovascular disease&#46; However&#44; the abnormal inflammatory response associated with COPD may provoke other disorders such as anemia&#46; Moreover&#44; comorbid anemia has been shown to be an independent predictor of mortality in several chronic diseases including cancer and heart failure&#46; Anemia is&#44; therefore&#44; an entity that should be taken into consideration in the overall management of respiratory disease because it may have a clear detrimental impact on various aspects of the patient&#39;s health&#44; including dyspnea&#44; exercise tolerance&#44; and quality of life&#46;</p><p class="elsevierStyleSimplePara elsevierViewall">There is a growing body of literature on the relationship between anemia and COPD&#46; Our aim is to briefly review the pathophysiologic aspects of this association before going on to discuss some of the most recent evidence published&#46;</p>"
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        "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">El reconocimiento reciente de la importancia que tienen las manifestaciones extrapulmonares&#44; tanto en el manejo como en el pron&#243;stico de la enfermedad pulmonar obstructiva cr&#243;nica &#40;EPOC&#41; ha llevado a que reconduzcamos las estrategias diagn&#243;sticas y terap&#233;uticas hacia ellas&#44; y que no centremos nuestros esfuerzos en valorar s&#243;lo una variable funcional &#40;el volumen espiratorio forzado en el primer segundo&#41; como marcador de supervivencia en estos pacientes&#46; Los trastornos sist&#233;micos relacionados con la EPOC m&#225;s estudiados son la p&#233;rdida de peso&#44; la disfunci&#243;n muscular&#44; la osteoporosis y la enfermedad cardiovascular&#46; Sin embargo&#44; hay otros posibles efectos&#44; como el s&#237;ndrome an&#233;mico&#44; que tambi&#233;n podr&#237;a ser consecuencia de la anormal respuesta inflamatoria que se produce en esta enfermedad&#46; Por otra parte&#44; la anemia como comorbilidad asociada a ciertas enfermedades cr&#243;nicas&#44; caso del c&#225;ncer y de la insuficiencia card&#237;aca&#44; ha demostrado actuar como un marcador de mortalidad independiente&#46; Se trata&#44; por lo tanto&#44; de una entidad que debe tenerse en cuenta en el manejo integral del paciente respiratorio&#44; ya que puede tener un impacto claramente perjudicial en diversos aspectos de la enfermedad&#44; como la disnea&#44; la tolerancia al ejercicio y la calidad de vida&#46;</p><p class="elsevierStyleSimplePara elsevierViewall">En la literatura m&#233;dica hay un n&#250;mero creciente de estudios que abordan la relaci&#243;n entre la anemia y la EPOC&#46; Esta revisi&#243;n se centrar&#225; en revisar brevemente los aspectos fisiopatol&#243;gicos relacionados con el tema y en discutir algunas de las &#250;ltimas evidencias publicadas hasta el momento&#46;</p>"
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Review Article
Anemia in COPD: Should It Be Taken Into Consideration?
Karina Portillo Carroz
Corresponding author
karisoe@yahoo.es

Correspondence: Dra K. Portillo Carroz. Servicio de Neumología. Consorcio Sanitario Integral. Hospital Dos de Maig. Dos de Maig, 301. 08025 Barcelona. España
Servicio de Neumología, Consorcio Sanitario Integral, Hospital Dos de Maig, Barcelona, Spain
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ISSN: 15792129
Original language: English
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2014 December 467 23 490
2014 November 656 16 672
2014 October 683 25 708
2014 September 561 17 578
2014 August 385 24 409
2014 July 397 26 423
2014 June 371 21 392
2014 May 395 16 411
2014 April 503 17 520
2014 March 437 18 455
2014 February 370 14 384
2014 January 212 9 221
2013 December 158 11 169
2013 November 174 15 189
2013 October 181 12 193
2013 September 220 6 226
2013 August 148 12 160
2013 July 125 12 137
2013 June 115 10 125
2013 May 106 9 115
2013 April 45 7 52
2013 March 10 2 12
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Archivos de Bronconeumología

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