Correspondence: Dr. C. Salinas, Servicio de Neumología. Hospital de Galdakao. B.° Labeaga, s/n, 48960 Galdakao. Bizkaia. España
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=> array:1 [ "colaborador" => "on behalf of the working group on Adherence to Tuberculosis Treatment in the Immigrant Population of the Community of Madrid (ATBIM)" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212907600780?idApp=UINPBA00003Z" "url" => "/15792129/0000004300000006/v1_201305150319/S1579212907600780/v1_201305150319/en/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S1579212907600767" "issn" => "15792129" "doi" => "10.1016/S1579-2129(07)60076-7" "estado" => "S300" "fechaPublicacion" => "2007-01-01" "aid" => "60076" "copyright" => "Sociedad Española de Neumología y Cirugía Torácica (SEPAR)" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Arch Bronconeumol. 2007;43:309-16" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 2494 "formatos" => array:3 [ "EPUB" => 108 "HTML" => 1611 "PDF" => 775 ] ] "en" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Original Articles</span>" "titulo" => "Prognostic Factors Associated With Resectable Pulmonary Metastases From Colorectal Cancer" "tienePdf" => "en" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "309" "paginaFinal" => "316" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Alberto Muñoz Llarena, Sergio Carrera Revilla, Aitziber Gil-Negrete Laborda, Joaquín Pac Ferrer, Ramón Barceló Galíndez, Guillermo López Vivanco" "autores" => array:6 [ 0 => array:2 [ "nombre" => "Alberto Muñoz" "apellidos" => "Llarena" ] 1 => array:2 [ "nombre" => "Sergio Carrera" "apellidos" => "Revilla" ] 2 => array:2 [ "nombre" => "Aitziber Gil-Negrete" "apellidos" => "Laborda" ] 3 => array:2 [ "nombre" => "Joaquín Pac" "apellidos" => "Ferrer" ] 4 => array:2 [ "nombre" => "Ramón Barceló" "apellidos" => "Galíndez" ] 5 => array:2 [ "nombre" => "Guillermo López" "apellidos" => "Vivanco" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212907600767?idApp=UINPBA00003Z" "url" => "/15792129/0000004300000006/v1_201305150319/S1579212907600767/v1_201305150319/en/main.assets" ] "en" => array:14 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Original Articles</span>" "titulo" => "Longitudinal Incidence of Tuberculosis in a Cohort of Contacts: Factors Associated With the Disease" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "317" "paginaFinal" => "323" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Carlos Salinas, Alberto Capelastegui, Lander Altube, Pedro Pablo España, Rosa Díez, Mikel Oribe, Isabel Urrutia, Urko Aguirre" "autores" => array:8 [ 0 => array:4 [ "nombre" => "Carlos" "apellidos" => "Salinas" "email" => array:1 [ 0 => "csalinas@hgda.osakidetza.net" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor1" ] ] ] 1 => array:3 [ "nombre" => "Alberto" "apellidos" => "Capelastegui" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 2 => array:3 [ "nombre" => "Lander" "apellidos" => "Altube" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 3 => array:3 [ "nombre" => "Pedro Pablo" "apellidos" => "España" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 4 => array:3 [ "nombre" => "Rosa" "apellidos" => "Díez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 5 => array:3 [ "nombre" => "Mikel" "apellidos" => "Oribe" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 6 => array:3 [ "nombre" => "Isabel" "apellidos" => "Urrutia" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 7 => array:3 [ "nombre" => "Urko" "apellidos" => "Aguirre" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Neumología, Hospital de Galdakao, Galdakao, Bizkaia, Spain" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:3 [ "entidad" => "Unidad de Investigación, Hospital de Galdakao, Galdakao, Bizkaia, Spain" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "*" "correspondencia" => "Correspondence: Dr. C. Salinas, Servicio de Neumología. Hospital de Galdakao. B.° Labeaga, s/n, 48960 Galdakao. Bizkaia. España" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2006-06-06" "fechaAceptado" => "2006-09-12" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec154896" "palabras" => array:3 [ 0 => "Tuberculosis" 1 => "Contact investigation" 2 => "Risk factors" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec154897" "palabras" => array:3 [ 0 => "Tuberculosis" 1 => "Estudio de contactos" 2 => "Factores de riesgo" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">OBJECTIVE</span><p class="elsevierStyleSimplePara elsevierViewall">To investigate the incidence of tuberculosis (TB) in a cohort of contacts and to analyze the variables associated with the disease.</p> <span class="elsevierStyleSectionTitle">METHODS</span><p class="elsevierStyleSimplePara elsevierViewall">A prospective analysis was undertaken of all the contact investigations carried out in a health district in the Basque Country in northern Spain between January 1, 1995 and December 31, 2004. The dependent variable was the number of cases of TB detected among the contacts. Independent variables were age, sex, tuberculin skin test result, and the degree of contact. In index cases, additional variables were the site of the disease and smear test result.</p> <span class="elsevierStyleSectionTitle">RESULTS</span><p class="elsevierStyleSimplePara elsevierViewall">Analysis of 5444 contacts of 596 patients with TB yielded 66 secondary cases of TB (40 at the time of the contact investigation and 26 at a later stage); the majority (73%) developed the disease within 12 months. Multivariate analysis revealed a significant relationship between the detection of secondary cases and the following variables: close contact (odds ratio [OR], 3.05; 95% confidence interval [CI], 1.75-5.31), positive smear test (OR, 8.54; 95% CI, 2.06-35.43), induration of 10 mm or larger (OR, 10.18; 95% CI, 4.27-24.26), and age under 30 years (OR, 3.35; 95% CI, 1.88-5.98). The final predictive model constructed on the basis of these 3 variables had a sensitivity of 77.4%, a specificity of 80.3%, and an area under the curve of 0.83 (95% CI, 0.78-0.88).</p> <span class="elsevierStyleSectionTitle">CONCLUSIONS</span><p class="elsevierStyleSimplePara elsevierViewall">The contact investigation is a valid strategy for the detection of new cases of TB. Prophylactic treatment should be implemented at an early stage, and priority should be given to young contacts of smear-positive patients using an induration size of 10 mm or more as a reference.</p>" ] "es" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">OBJETIVO</span><p class="elsevierStyleSimplePara elsevierViewall">Conocer la incidencia de tuberculosis (TB) en una cohorte de contactos y analizar las variables asociadas a la enfermedad.</p> <span class="elsevierStyleSectionTitle">MÉTODOS</span><p class="elsevierStyleSimplePara elsevierViewall">Se ha efectuado un análisis prospectivo de los estudios de contactos (EC) realizados en un área sanitaria del País Vasco del 1 de enero de 1995 al 31 de diciembre de 2004. La variable dependiente fue el número de casos de TB detectados entre los contactos. Las variables independientes fueron la edad, el sexo, la prueba de la tuberculina (PT) y el grado de contacto, y en los casos índice, la localización de la TB y la baciloscopia del esputo.</p> <span class="elsevierStyleSectionTitle">RESULTADOS</span><p class="elsevierStyleSimplePara elsevierViewall">De los 5.444 contactos de 596 pacientes con TB que se estudiaron, se encontraron 66 casos secundarios de TB (40 en el momento del EC y 26 en el período posterior), la mayoría de ellos (73%) durante el primer año. El análisis multivariante demostró una relación significativa entre la detección de casos secundarios y las siguientes variables: contacto íntimo (<span class="elsevierStyleItalic">odds ratio</span> [OR] = 3,05; intervalo de confianza [IC] del 95%, 1,75-5,31), baciloscopia positiva (OR = 8,54; IC del 95%, 2,06-35,43), PT de 10 mm o mayor (OR = 10,18; IC del 95%, 4,27-24,26) y edad inferior a 30 años (OR = 3,35; IC del 95%, 1,88-5,98). El modelo predictivo final que se obtuvo utilizando estas 3 variables alcanzó una sensibilidad del 77,4%, una especificidad del 80,3% y un área bajo la curva de 0,83 (IC del 95%, 0,78-0,88).</p> <span class="elsevierStyleSectionTitle">CONCLUSIONES</span><p class="elsevierStyleSimplePara elsevierViewall">El EC es una estrategia válida para la detección de nuevos casos de TB. La intervención profiláctica debería realizarse de forma precoz y dirigirse prioritariamente a los contactos jóvenes de pacientes bacilíferos, utilizando como referencia una PT de 10 mm o mayor.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "REFERENCES" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:32 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Essential components of a tuberculosis prevention and control program. 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Year/Month | Html | Total | |
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2024 November | 5 | 4 | 9 |
2024 October | 27 | 15 | 42 |
2024 September | 24 | 18 | 42 |
2024 August | 43 | 38 | 81 |
2024 July | 27 | 23 | 50 |
2024 June | 32 | 26 | 58 |
2024 May | 32 | 29 | 61 |
2024 April | 17 | 23 | 40 |
2024 March | 19 | 14 | 33 |
2024 February | 20 | 16 | 36 |
2023 March | 3 | 4 | 7 |
2023 February | 13 | 18 | 31 |
2023 January | 17 | 24 | 41 |
2022 December | 20 | 28 | 48 |
2022 November | 18 | 16 | 34 |
2022 October | 18 | 24 | 42 |
2022 September | 15 | 26 | 41 |
2022 August | 27 | 31 | 58 |
2022 July | 21 | 37 | 58 |
2022 June | 15 | 32 | 47 |
2022 May | 17 | 34 | 51 |
2022 April | 16 | 30 | 46 |
2022 March | 19 | 41 | 60 |
2022 February | 15 | 29 | 44 |
2022 January | 19 | 38 | 57 |
2021 December | 14 | 42 | 56 |
2021 November | 12 | 50 | 62 |
2021 October | 24 | 37 | 61 |
2021 September | 17 | 62 | 79 |
2021 August | 13 | 28 | 41 |
2021 July | 10 | 23 | 33 |
2021 June | 10 | 30 | 40 |
2021 May | 12 | 24 | 36 |
2021 April | 6 | 19 | 25 |
2021 March | 15 | 14 | 29 |
2021 February | 7 | 11 | 18 |
2021 January | 9 | 14 | 23 |
2020 December | 6 | 12 | 18 |
2020 November | 6 | 8 | 14 |
2020 October | 6 | 5 | 11 |
2020 September | 6 | 1 | 7 |
2020 August | 8 | 9 | 17 |
2020 July | 6 | 12 | 18 |
2020 June | 6 | 6 | 12 |
2020 May | 10 | 12 | 22 |
2020 April | 13 | 14 | 27 |
2020 March | 14 | 9 | 23 |
2020 February | 19 | 16 | 35 |
2020 January | 10 | 14 | 24 |
2019 December | 17 | 10 | 27 |
2019 November | 11 | 10 | 21 |
2019 October | 6 | 4 | 10 |
2019 September | 8 | 13 | 21 |
2019 August | 15 | 9 | 24 |
2019 July | 15 | 15 | 30 |
2019 June | 8 | 3 | 11 |
2019 May | 13 | 5 | 18 |
2019 April | 11 | 7 | 18 |
2019 March | 9 | 10 | 19 |
2019 February | 7 | 10 | 17 |
2019 January | 6 | 4 | 10 |
2018 December | 9 | 9 | 18 |
2018 November | 8 | 15 | 23 |
2018 October | 21 | 21 | 42 |
2018 September | 10 | 12 | 22 |
2018 May | 6 | 0 | 6 |
2018 April | 4 | 4 | 8 |
2018 March | 6 | 5 | 11 |
2018 February | 8 | 8 | 16 |
2018 January | 2 | 5 | 7 |
2017 December | 4 | 5 | 9 |
2017 November | 6 | 4 | 10 |
2017 October | 5 | 8 | 13 |
2017 September | 7 | 3 | 10 |
2017 August | 4 | 10 | 14 |
2017 July | 2 | 10 | 12 |
2017 June | 8 | 25 | 33 |
2017 May | 7 | 7 | 14 |
2017 April | 0 | 3 | 3 |
2017 March | 3 | 6 | 9 |
2017 February | 0 | 1 | 1 |
2017 January | 2 | 2 | 4 |
2016 December | 7 | 3 | 10 |
2016 November | 5 | 8 | 13 |
2016 October | 5 | 3 | 8 |
2016 September | 3 | 3 | 6 |
2016 August | 7 | 5 | 12 |
2016 March | 2 | 0 | 2 |
2015 December | 2 | 0 | 2 |
2015 October | 31 | 8 | 39 |
2015 September | 32 | 5 | 37 |
2015 August | 28 | 6 | 34 |
2015 July | 30 | 13 | 43 |
2015 June | 30 | 3 | 33 |
2015 May | 41 | 5 | 46 |
2015 April | 24 | 8 | 32 |
2015 March | 38 | 6 | 44 |
2015 February | 33 | 2 | 35 |
2015 January | 25 | 11 | 36 |
2014 December | 27 | 2 | 29 |
2014 November | 20 | 11 | 31 |
2014 October | 42 | 10 | 52 |
2014 September | 25 | 11 | 36 |
2014 August | 35 | 19 | 54 |
2014 July | 20 | 6 | 26 |
2014 June | 40 | 12 | 52 |
2014 May | 37 | 16 | 53 |
2014 April | 44 | 8 | 52 |
2014 March | 58 | 10 | 68 |
2014 February | 39 | 9 | 48 |
2014 January | 40 | 8 | 48 |
2013 December | 35 | 10 | 45 |
2013 November | 22 | 6 | 28 |
2013 October | 27 | 9 | 36 |
2013 September | 24 | 9 | 33 |
2013 August | 35 | 13 | 48 |
2013 July | 44 | 14 | 58 |
2013 June | 25 | 12 | 37 |
2013 May | 30 | 8 | 38 |
2013 April | 30 | 8 | 38 |
2013 March | 12 | 5 | 17 |