Original Articles
Usefulness of Endoscopic Ultrasound-Guided Fine Needle Aspiration in the Diagnosis of Mediastinal Lesions
Glòria Fernández-Esparracha, Maria Pelliséa, Manel Soléb, Josep Beldac, Oriol Sendinoa, Josep Llacha, Alfredo Mataa, Josep Maria Bordasa, Àngels Ginèsa,
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magines@clinic.ub.es
Correspondence: Dra. A. Ginès. Unidad de Endoscopia. Institut de Malalties Digestives. Hospital Clínic. Villarroel, 170. 08036 Barcelona. España
Correspondence: Dra. A. Ginès. Unidad de Endoscopia. Institut de Malalties Digestives. Hospital Clínic. Villarroel, 170. 08036 Barcelona. España
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A. Ginès. Unidad de Endoscopia. Institut de Malalties Digestives. Hospital Clínic. Villarroel, 170. 08036 Barcelona. España" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2006-02-22" "fechaAceptado" => "2006-09-19" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec154847" "palabras" => array:3 [ 0 => "Fine-needle aspiration" 1 => "Endoscopic ultrasound" 2 => "Mediastinum" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec154846" "palabras" => array:3 [ 0 => "Punción aspirativa" 1 => "Ultrasonografía endoscópica" 2 => "Mediastino" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) is a safe and effective technique for the diagnosis of focal pancreatic lesions and enlarged abdominal lymph nodes. The aim of this study was to assess the usefulness of EUS-FNA in the diagnosis of mediastinal lesions.</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p class="elsevierStyleSimplePara elsevierViewall">A retrospective review was performed of all consecutive cases in which EUS-FNA was used for the diagnosis of a mediastinal lesion between January 2001 and September 2003. We used a radial echoendoscope to assess the characteristics of the lesion and a linear-array echoendoscope to perform transesophageal needle aspiration with a 22-gauge needle. Histopathology of the resected specimen was considered as the gold standard in surgically treated patients whereas cytology obtained by EUS-FNA was the gold standard when surgery was not indicated.</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">EUS-FNA was performed in 59 patients with a total of 89 lesions with mean (SD) dimensions of 2.4 (2.0) cm × 1.6 (1.4) cm. Malignant lesions were larger than benign ones (short axis, 2.7 [1.4] as compared with 1.0 [0.9] cm; <span class="elsevierStyleItalic">P</span> <.001). The diagnosis was obtained for 53 patients (90%) and 81 lesions (91%) with a mean of 2 (1) passes per lesion. The sensitivity, specificity, positive and negative predictive values, and diagnostic accuracy of EUS-FNA were 81%, 100%, 100%, 75%, and 88%, respectively, when analyzed by lesion, and 88%, 100%, 100%, 80%, and 92% when analyzed by patient.</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">EUS-FNA is an effective technique for the diagnosis of mediastinal lesions. The likelihood of malignancy increases with size.</p>" ] "es" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">La punción aspirativa con aguja fina guiada por ultrasonografía endoscópica (USE-PAAF) es una técnica eficaz y segura en el diagnóstico de las lesiones focales del páncreas y las adenopatías intraabdominales. El objetivo de este estudio es describir su utilidad en el diagnóstico de las lesiones mediastínicas.</p> <span class="elsevierStyleSectionTitle">Pacientes y métodos</span><p class="elsevierStyleSimplePara elsevierViewall">Se han revisado todos los casos consecutivos a los que se realizó una USE-PAAF para estudio de una lesión mediastínica desde enero de 2001 hasta septiembre de 2003. Las exploraciones se efectuaron con un ecoendoscopio radial para estudio de las características de la lesión y un ecoendoscopio sectorial para realizar la punción transesofágica usando una aguja de 22 G. Se utilizó como referencia la cirugía en los pacientes operados y el resultado de la citología obtenida con la USE-PAAF en los casos en que el tratamiento quirúrgico no estaba indicado.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Se realizó USE-PAAF a 59 pacientes con un total de 89 lesiones, con diámetro medio ± desviación estándar de 2,4 ± 2 × 1,6 ± 1,4 cm. El tamaño de las lesiones malignas fue mayor que el de las benignas (diámetro corto: 2,7 ± 1,4 frente a 1 ± 0,9 cm, respectivamente; p < 0,001). El material obtenido permitió el diagnóstico en 53 pacientes (90%) y en 81 lesiones (91%), y el número de pases fue de 2 ± 1 por lesión. La sensibilidad, la especificidad, el valor predictivo positivo, el valor predictivo negativo y la precisión para el diagnóstico fueron del 81, el 100, el 100, el 75 y el 88%, respectivamente (el 88, el 100, el 100, el 80 y el 92% al analizarlos por paciente).</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">La USE-PAAF es una técnica eficaz en el estudio de la patología mediastínica. La probabilidad de malignidad es mayor cuanto mayor es el tamaño de la lesión.</p>" ] ] "NotaPie" => array:1 [ 0 => array:1 [ "nota" => "<p class="elsevierStyleNotepara">This study was partially funded by a grant from Instituto de Salud Carlos III (03/10066).</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:30 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Imaging of mediastinal lymph nodes: CT, MR, and FDG PET" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "PM Boiselle" 1 => "EF Patz" 2 => "DJ Vining" 3 => "R Weissleder" 4 => "JA Shepard" 5 => "TC McLoud" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1148/radiographics.18.5.9747607" "Revista" => array:6 [ "tituloSerie" => "Radiographics" "fecha" => "1998" "volumen" => "18" "paginaInicial" => "1061" "paginaFinal" => "1069" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9747607" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pathological assessment of mediastinal lymph nodes in lung cancer: Implications for non-invasive mediastinal staging" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "KM Kerr" 1 => "D Lamb" 2 => "GG Wathen" 3 => "WS Walker" 4 => "NJ Douglas" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Thorax" "fecha" => "1992" "volumen" => "47" "paginaInicial" => "337" "paginaFinal" => "341" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1609375" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib3" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Endoscopic ultrasound with fine-needle aspiration in the diagnosis and staging of lung cancer" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "GA Silvestri" 1 => "BJ Hoffman" 2 => "MS Buthani" 3 => "RH Hawes" 4 => "L Coppage" 5 => "A Sanders-Cliette" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/0003-4975(95)00052-6" "Revista" => array:6 [ "tituloSerie" => "Ann Thorac Surg" "fecha" => "1996" "volumen" => "61" "paginaInicial" => "1441" "paginaFinal" => "1446" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8633956" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib4" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Endoscopic ultrasonography, fine needle aspiration guided by endoscopic ultrasonography and computed tomography in the preoperative staging of non-small cell lung cancer: a comparison study" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "F Gress" 1 => "TJ Savides" 2 => "A Sandier" 3 => "K Kesler" 4 => "D Conces" 5 => "O Cummings" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Ann Intern Med" "fecha" => "1997" "volumen" => "127" "paginaInicial" => "604" "paginaFinal" => "612" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9341058" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib5" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Role of transesophageal endosonography-guided fine-needle aspiration in the diagnosis of lung cancer" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "A Fritscher-Ravens" 1 => "N Soehendra" 2 => "L Schirrow" 3 => "PV Sriram" 4 => "A Meyer" 5 => "HP Hauber" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "2000" "volumen" => "117" "paginaInicial" => "339" "paginaFinal" => "345" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10669672" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib6" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Impact of EUS-guided fine-needle aspiration on lymph node staging in patients with esophageal carcinoma" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "E Vázquez-Sequeiros" 1 => "ID Norton" 2 => "JE Clain" 3 => "KK Wang" 4 => "A Affi" 5 => "M Allen" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1067/mge.2001.112741" "Revista" => array:6 [ "tituloSerie" => "Gastrointest Endosc" "fecha" => "2001" "volumen" => "53" "paginaInicial" => "751" "paginaFinal" => "757" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11375583" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib7" "etiqueta" => "7" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Real-time endoscopic ultrasound-guided fine-needle aspiration of a mediastinal lymph node" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "MJ Wiersema" 1 => "ML Kochman" 2 => "A Chak" 3 => "HM Cramer" 4 => "KA Kesler" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Gastrointest Endosc" "fecha" => "1993" "volumen" => "39" "paginaInicial" => "429" "paginaFinal" => "431" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8390383" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib8" "etiqueta" => "8" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "An early comparison between endoscopic ultrasound-guided fineneedle aspiration and mediastinoscopy for diagnosis of mediastinal malignancy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "DL Serna" 1 => "HE Aryan" 2 => "KJ Chang" 3 => "M Brenner" 4 => "LM Tran" 5 => "JC Chen" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am Surg" "fecha" => "1998" "volumen" => "64" "paginaInicial" => "1014" "paginaFinal" => "1018" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9764715" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib9" "etiqueta" => "9" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Mediastinal lymphadenopathy in patients with or without obvious malignancy: EUS-FNA based differential cytodiagnosis in 153 patients" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "A Fritscher-Ravens" 1 => "PV Sriram" 2 => "C Bobrowski" 3 => "A Pforte" 4 => "T Topalidis" 5 => "C Krause" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1572-0241.2000.02243.x" "Revista" => array:6 [ "tituloSerie" => "Am J Gastroenterol" "fecha" => "2000" "volumen" => "95" "paginaInicial" => "2278" "paginaFinal" => "2284" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11007229" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib10" "etiqueta" => "10" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A descriptive analysis of EUS-FNA for mediastinal lymphadenopathy: an emphasis on clinical impact and false negative results" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "LV Hernández" 1 => "G Mishra" 2 => "S George" 3 => "M Buthani" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Gastroenterol" "fecha" => "2004" "volumen" => "99" "paginaInicial" => "249" "paginaFinal" => "254" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15046212" "web" => "Medline" ] ] ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib11" "etiqueta" => "11" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Endoscopic ultrasound guided biopsy of mediastinal lesions has a major impact on patient management" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "SS Larsen" 1 => "M Krasnik" 2 => "P Vilmann" 3 => "GK Jacobsen" 4 => "JH Pedersen" 5 => "P Faurschou" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Thorax" "fecha" => "2002" "volumen" => "57" "paginaInicial" => "98" "paginaFinal" => "103" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11828036" "web" => "Medline" ] ] ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib12" "etiqueta" => "12" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Epidemiology of extrapulmonary tuberculosis. A comparative analysis with pre-AIDS era" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "JB Menta" 1 => "A Dutt" 2 => "L Harvill" 3 => "KM Mathews" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "1991" "volumen" => "99" "paginaInicial" => "1134" "paginaFinal" => "1138" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2019168" "web" => "Medline" ] ] ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib13" "etiqueta" => "13" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Tuberculosis e infección por VIH. Evaluación de 132 casos" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "V Cárcaba" 1 => "JA Cartón" 2 => "J Morís" 3 => "Z García Amorín" 4 => "M García Clemente" 5 => "M Rodríguez Junquera" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Rev Clin Esp" "fecha" => "1993" "volumen" => "193" "paginaInicial" => "12" "paginaFinal" => "16" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8337453" "web" => "Medline" ] ] ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib14" "etiqueta" => "14" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intrathoracic lymph node metastases from extrathoracic neoplasms" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "T McCloud" 1 => "L Kalisher" 2 => "L Stark" 3 => "R Greene" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "JR Am J Roentgenol" "fecha" => "1978" "volumen" => "131" "paginaInicial" => "403" "paginaFinal" => "407" ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib15" "etiqueta" => "15" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Endoscopic ultrasound-guided fine-needle aspiration in patients with mediastinal abnormalities and previous extrathoracic malignancy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "H Kramer" 1 => "GH Koeter" 2 => "DT Sleijfer" 3 => "JW Van Putten" 4 => "HJ Groen" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.ejca.2003.11.010" "Revista" => array:6 [ "tituloSerie" => "Eur J Cancer" "fecha" => "2004" "volumen" => "40" "paginaInicial" => "559" "paginaFinal" => "562" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14962723" "web" => "Medline" ] ] ] ] ] ] ] ] 15 => array:3 [ "identificador" => "bib16" "etiqueta" => "16" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Fine-needle aspiration cytology guided by endoscopic ultrasonography: results in 141 patients" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "M Giovanini" 1 => "JF Seitz" 2 => "G Monges" 3 => "H Perrier" 4 => "I Rabbia" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1055/s-2007-1005657" "Revista" => array:6 [ "tituloSerie" => "Endoscopy" "fecha" => "1995" "volumen" => "27" "paginaInicial" => "171" "paginaFinal" => "177" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7601050" "web" => "Medline" ] ] ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bib17" "etiqueta" => "17" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Endosonography-guided fine-needle aspiration biopsy: diagnostic accuracy and complication assessment" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "MJ Wiersema" 1 => "P Vilmann" 2 => "M Giovannini" 3 => "KJ Chang" 4 => "LM Wiersema" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Gastroenterology" "fecha" => "1997" "volumen" => "112" "paginaInicial" => "1087" "paginaFinal" => "1095" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9097990" "web" => "Medline" ] ] ] ] ] ] ] ] 17 => array:3 [ "identificador" => "bib18" "etiqueta" => "18" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Clinical impact of endoscopic ultrasound-guided fine needle aspiration biopsy in patients with upper gastrointestinal tract malignancies. A prospective study" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "MB Mortensen" 1 => "T Pless" 2 => "AP Ainsworth" 3 => "GJ Plagborg" 4 => "C Hovendal" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1055/s-2001-14966" "Revista" => array:6 [ "tituloSerie" => "Endoscopy" "fecha" => "2001" "volumen" => "33" "paginaInicial" => "478" "paginaFinal" => "483" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11437039" "web" => "Medline" ] ] ] ] ] ] ] ] 18 => array:3 [ "identificador" => "bib19" "etiqueta" => "19" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Endoscopic ultrasound-guided fine needle aspiration is superior to lymph node echofeatures: a prospective evaluation of mediastinal and peri-intestinal lymphadenopathy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "VK Chen" 1 => "MA Eloubeidi" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1572-0241.2004.04064.x" "Revista" => array:6 [ "tituloSerie" => "Am J Gastroenterol" "fecha" => "2004" "volumen" => "99" "paginaInicial" => "628" "paginaFinal" => "633" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15089893" "web" => "Medline" ] ] ] ] ] ] ] ] 19 => array:3 [ "identificador" => "bib20" "etiqueta" => "20" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cost-efficacy of endoscopic ultrasonography with fine-needle aspiration vs mediastinotomy in patients with lung cancer and suspected mediastinal adenopathy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "L Aabakken" 1 => "GA Silvestri" 2 => "R Hawes" 3 => "CE Reed" 4 => "V Marsi" 5 => "B Hoffman" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1055/s-1999-74" "Revista" => array:6 [ "tituloSerie" => "Endoscopy" "fecha" => "1999" "volumen" => "31" "paginaInicial" => "707" "paginaFinal" => "711" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10604611" "web" => "Medline" ] ] ] ] ] ] ] ] 20 => array:3 [ "identificador" => "bib21" "etiqueta" => "21" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Endoscopic ultrasound versus computed tomography in the evaluation of the mediastinum in patients with non-small cell lung cancer" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "R Hawes" 1 => "F Gress" 2 => "K Kesler" 3 => "O Cummings" 4 => "D Conces" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1055/s-2007-1009106" "Revista" => array:6 [ "tituloSerie" => "Endoscopy" "fecha" => "1994" "volumen" => "26" "paginaInicial" => "784" "paginaFinal" => "787" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7712989" "web" => "Medline" ] ] ] ] ] ] ] ] 21 => array:3 [ "identificador" => "bib22" "etiqueta" => "22" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Evaluation of mediastinal lymphadenopathy with endoscopic US-guided fineneedle aspiration biopsy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "MJ Wiersema" 1 => "E Vázquez-Sequeiros" 2 => "LM Wiersema" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1148/radiology.219.1.r01ap44252" "Revista" => array:6 [ "tituloSerie" => "Radiology" "fecha" => "2001" "volumen" => "219" "paginaInicial" => "252" "paginaFinal" => "257" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11274566" "web" => "Medline" ] ] ] ] ] ] ] ] 22 => array:3 [ "identificador" => "bib23" "etiqueta" => "23" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Endobronchial and endoscopic ultrasound-guided real-time fine-needle aspiration for mediastinal staging" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "RC Rintoul" 1 => "KM Skwarski" 2 => "JT Murchison" 3 => "WA Wallace" 4 => "WS Walker" 5 => "ID Penman" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1183/09031936.05.00095404" "Revista" => array:6 [ "tituloSerie" => "Eur Respir J" "fecha" => "2005" "volumen" => "25" "paginaInicial" => "416" "paginaFinal" => "421" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15738283" "web" => "Medline" ] ] ] ] ] ] ] ] 23 => array:3 [ "identificador" => "bib24" "etiqueta" => "24" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Real-time endobronchial ultrasound-guided transbronchial needle aspiration of mediastinal and hilar lymph nodes" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "K Yasufuku" 1 => "M Chiyo" 2 => "Y Sekine" 3 => "PN Chhajed" 4 => "K Shibuya" 5 => "T Lizasa" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1378/chest.126.1.122" "Revista" => array:6 [ "tituloSerie" => "Chest" "fecha" => "2004" "volumen" => "126" "paginaInicial" => "122" "paginaFinal" => "128" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15249452" "web" => "Medline" ] ] ] ] ] ] ] ] 24 => array:3 [ "identificador" => "bib25" "etiqueta" => "25" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Endoscopic ultrasound in lung cancer patients with a normal mediastinum on computed tomography" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "MB Wallace" 1 => "J Ravenel" 2 => "MI Block" 3 => "M Fraig" 4 => "G Silvestri" 5 => "S Wildi" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.athoracsur.2003.10.009" "Revista" => array:6 [ "tituloSerie" => "Ann Thorac Surg" "fecha" => "2004" "volumen" => "77" "paginaInicial" => "1763" "paginaFinal" => "1768" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15111182" "web" => "Medline" ] ] ] ] ] ] ] ] 25 => array:3 [ "identificador" => "bib26" "etiqueta" => "26" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Operating characteristics and clinical utility of endoscopic ultrasound (EUS) guided FNA in the preoperative staging of nonsmall cell lung cancer (NSCLCA) in computerized tomographic negative patients: preliminary results" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "D Ciaccia" 1 => "T Imperiale" 2 => "J Kim" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Gastrointest Endosc" "fecha" => "1999" "volumen" => "49" "paginaInicial" => "AB154" ] ] ] ] ] ] 26 => array:3 [ "identificador" => "bib27" "etiqueta" => "27" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Transbronchial vs transesophageal ultrasound-guided aspiration of enlarged mediastinal lymph nodes" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "FJF Herth" 1 => "W Lunn" 2 => "R Eberhardt" 3 => "HD Becker" 4 => "A Ernst" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1164/rccm.200411-1560OC" "Revista" => array:6 [ "tituloSerie" => "Am J Respir Crit Care Med" "fecha" => "2005" "volumen" => "171" "paginaInicial" => "1164" "paginaFinal" => "1167" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15665318" "web" => "Medline" ] ] ] ] ] ] ] ] 27 => array:3 [ "identificador" => "bib28" "etiqueta" => "28" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Clinical utility of EUS-guided fine-needle aspiration of mediastinal masses in the absence of known pulmonary malignancy" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "BM Devereaux" 1 => "JK LeBlanc" 2 => "E Yousif" 3 => "K Kesler" 4 => "J Brooks" 5 => "P Mathur" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Gastrointest Endosc" "fecha" => "2002" "volumen" => "56" "paginaInicial" => "397" "paginaFinal" => "401" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12196779" "web" => "Medline" ] ] ] ] ] ] ] ] 28 => array:3 [ "identificador" => "bib29" "etiqueta" => "29" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Improving the accuracy of ultrasound-guided fine-needle aspiration (EUS-FNA): factors predicting a correct diagnosis and usefulness of an attendant pathologist" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "M Pellisé" 1 => "A Ginès" 2 => "M Solé" 3 => "D Vera" 4 => "G Fernández-Esparrach" 5 => "A Castells" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Gastrointest Endosc" "fecha" => "2004" "volumen" => "59" "paginaInicial" => "AB236" ] ] ] ] ] ] 29 => array:3 [ "identificador" => "bib30" "etiqueta" => "30" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Diagnosis of benign cysts of the mediastinum: the role and risks of EUS-FNA" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "SM Wildi" 1 => "RS Hoda" 2 => "W Fickling" 3 => "N Schmulewitz" 4 => "S Varadarajulu" 5 => "SS Roberts" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Gastrointest Endosc" "fecha" => "2003" "volumen" => "58" "paginaInicial" => "362" "paginaFinal" => "368" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14528209" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15792129/0000004300000004/v1_201305150314/S1579212907600548/v1_201305150314/en/main.assets" "Apartado" => null "PDF" => 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| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 4 | 3 | 7 |
| 2024 October | 26 | 14 | 40 |
| 2024 September | 30 | 21 | 51 |
| 2024 August | 42 | 41 | 83 |
| 2024 July | 28 | 18 | 46 |
| 2024 June | 38 | 22 | 60 |
| 2024 May | 34 | 26 | 60 |
| 2024 April | 21 | 22 | 43 |
| 2024 March | 20 | 15 | 35 |
| 2024 February | 21 | 19 | 40 |
| 2023 March | 3 | 1 | 4 |
| 2023 February | 16 | 18 | 34 |
| 2023 January | 16 | 22 | 38 |
| 2022 December | 26 | 26 | 52 |
| 2022 November | 19 | 19 | 38 |
| 2022 October | 21 | 27 | 48 |
| 2022 September | 17 | 21 | 38 |
| 2022 August | 17 | 40 | 57 |
| 2022 July | 16 | 30 | 46 |
| 2022 June | 20 | 34 | 54 |
| 2022 May | 14 | 28 | 42 |
| 2022 April | 18 | 25 | 43 |
| 2022 March | 18 | 42 | 60 |
| 2022 February | 19 | 21 | 40 |
| 2022 January | 24 | 20 | 44 |
| 2021 December | 49 | 43 | 92 |
| 2021 November | 23 | 43 | 66 |
| 2021 October | 17 | 45 | 62 |
| 2021 September | 15 | 63 | 78 |
| 2021 August | 13 | 26 | 39 |
| 2021 July | 13 | 28 | 41 |
| 2021 June | 10 | 37 | 47 |
| 2021 May | 15 | 31 | 46 |
| 2021 April | 15 | 32 | 47 |
| 2021 March | 26 | 22 | 48 |
| 2021 February | 11 | 23 | 34 |
| 2021 January | 9 | 12 | 21 |
| 2020 December | 13 | 16 | 29 |
| 2020 November | 13 | 13 | 26 |
| 2020 October | 6 | 6 | 12 |
| 2020 September | 41 | 1 | 42 |
| 2020 August | 55 | 7 | 62 |
| 2020 July | 27 | 21 | 48 |
| 2020 June | 14 | 9 | 23 |
| 2020 May | 22 | 13 | 35 |
| 2020 April | 36 | 13 | 49 |
| 2020 March | 46 | 12 | 58 |
| 2020 February | 65 | 17 | 82 |
| 2020 January | 41 | 19 | 60 |
| 2019 December | 28 | 20 | 48 |
| 2019 November | 18 | 13 | 31 |
| 2019 October | 4 | 10 | 14 |
| 2019 September | 9 | 16 | 25 |
| 2019 August | 12 | 13 | 25 |
| 2019 July | 15 | 24 | 39 |
| 2019 June | 9 | 16 | 25 |
| 2019 May | 6 | 18 | 24 |
| 2019 April | 36 | 40 | 76 |
| 2019 March | 11 | 22 | 33 |
| 2019 February | 14 | 16 | 30 |
| 2019 January | 1 | 12 | 13 |
| 2018 December | 7 | 15 | 22 |
| 2018 November | 10 | 11 | 21 |
| 2018 October | 16 | 15 | 31 |
| 2018 September | 17 | 14 | 31 |
| 2018 May | 2 | 1 | 3 |
| 2018 April | 8 | 12 | 20 |
| 2018 March | 7 | 4 | 11 |
| 2018 February | 7 | 11 | 18 |
| 2018 January | 9 | 11 | 20 |
| 2017 December | 13 | 12 | 25 |
| 2017 November | 7 | 14 | 21 |
| 2017 October | 8 | 11 | 19 |
| 2017 September | 4 | 6 | 10 |
| 2017 August | 4 | 16 | 20 |
| 2017 July | 5 | 8 | 13 |
| 2017 June | 10 | 12 | 22 |
| 2017 May | 6 | 10 | 16 |
| 2017 April | 2 | 2 | 4 |
| 2017 March | 1 | 4 | 5 |
| 2017 February | 3 | 4 | 7 |
| 2017 January | 1 | 2 | 3 |
| 2016 December | 10 | 12 | 22 |
| 2016 November | 18 | 9 | 27 |
| 2016 October | 15 | 14 | 29 |
| 2016 September | 17 | 12 | 29 |
| 2016 August | 21 | 9 | 30 |
| 2016 July | 10 | 6 | 16 |
| 2016 April | 3 | 0 | 3 |
| 2016 March | 2 | 0 | 2 |
| 2015 December | 2 | 0 | 2 |
| 2015 October | 79 | 13 | 92 |
| 2015 September | 84 | 7 | 91 |
| 2015 August | 83 | 11 | 94 |
| 2015 July | 71 | 9 | 80 |
| 2015 June | 57 | 3 | 60 |
| 2015 May | 77 | 9 | 86 |
| 2015 April | 55 | 6 | 61 |
| 2015 March | 40 | 2 | 42 |
| 2015 February | 52 | 5 | 57 |
| 2015 January | 54 | 7 | 61 |
| 2014 December | 53 | 3 | 56 |
| 2014 November | 57 | 9 | 66 |
| 2014 October | 76 | 7 | 83 |
| 2014 September | 67 | 6 | 73 |
| 2014 August | 54 | 8 | 62 |
| 2014 July | 61 | 7 | 68 |
| 2014 June | 76 | 10 | 86 |
| 2014 May | 71 | 10 | 81 |
| 2014 April | 70 | 4 | 74 |
| 2014 March | 67 | 7 | 74 |
| 2014 February | 67 | 15 | 82 |
| 2014 January | 61 | 9 | 70 |
| 2013 December | 70 | 9 | 79 |
| 2013 November | 74 | 5 | 79 |
| 2013 October | 70 | 4 | 74 |
| 2013 September | 55 | 7 | 62 |
| 2013 August | 48 | 5 | 53 |
| 2013 July | 66 | 12 | 78 |
| 2013 June | 49 | 6 | 55 |
| 2013 May | 62 | 3 | 65 |
| 2013 April | 28 | 6 | 34 |
| 2013 March | 10 | 1 | 11 |
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