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        "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">To study self-perceived quality of life in adults with cystic fibrosis &#40;CF&#41;&#44; and to assess the validity of the St George&#39;s Respiratory Questionnaire &#40;SGRQ&#41; for use in these patients&#46;</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p class="elsevierStyleSimplePara elsevierViewall">We studied 37 adults with CF who were in stable condition as indicated by their respiratory and nutritional status&#46; Disease severity was assessed by spirometry used in conjunction with a modified National Institutes of Health &#40;NIH&#41; scoring system and the Bhalla scale&#46; Nutritional status was evaluated by measuring height and weight&#44; calculating body mass index&#44; analyzing bioelectric impedance&#44; and performing various laboratory tests&#46; The patients&#39; quality of life was assessed using the SGRQ&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">SGRQ scores were higher &#40;indicating poorer quality of life&#41; among patients with CF than in the general population or among patients with chronic obstructive pulmonary disease&#46; Internal consistency coefficients indicated the SGRQ had good reliability &#40;Cronbach&#39;s alpha&#44; 0&#46;864&#41;&#46; Women with CF tended to score higher than men&#44; although this difference was not statistically significantly&#46; A statistically significant relationship was observed between SGRQ score and severity of pulmonary impairment &#40;the more severe the impairment&#44; the worse the patient&#39;s quality of life&#41;&#46; Statistically significant positive relationships were found between SGRQ domains and age&#44; body mass index&#44; and body fat percentage&#46; Significant negative relationships were found between these domains and the modified NIH score&#44; the Bhalla score&#44; forced expiratory volume in 1 second &#40;expressed as a percentage of predicted&#41;&#44; and somatomedin C and zinc levels&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">Self-perceived quality of life is worse among adults with CF than in the general population or among patients with chronic obstructive pulmonary disease&#46; The SGRQ is a valid instrument for analyzing health-related quality of life in adults with CF as it discriminates very well between different degrees of severity of pulmonary impairment and has acceptable internal consistency&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">Estudiar la percepci&#243;n de la calidad de vida &#40;CV&#41; en una poblaci&#243;n adulta con fibrosis qu&#237;stica &#40;FQ&#41; y valorar la validez del Cuestionario Respiratorio St&#46; George &#40;SGRQ&#41; en estos pacientes&#46;</p> <span class="elsevierStyleSectionTitle">Pacientes y m&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">Hemos estudiado a 37 personas adultas con FQ&#44; estables desde el punto de vista respiratorio y nutricional&#46; Se realiz&#243; una valoraci&#243;n de la gravedad de la enfermedad mediante espirometr&#237;a y los sistemas NIH &#40;National Institutes of Health&#41; modificado y Bhalla&#44; as&#237; como una valoraci&#243;n nutricional mediante la medici&#243;n del peso&#44; la talla&#44; el &#237;ndice de masa corporal&#44; impedanciometr&#237;a bioel&#233;ctrica y par&#225;metros anal&#237;ticos&#46; Se estim&#243; la percepci&#243;n de la CV mediante el SGRQ&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Las personas con FQ tienen mayores puntuaciones &#40;peor CV&#41; que la poblaci&#243;n general y que los afectados de enfermedad pulmonar obstructiva cr&#243;nica &#40;EPOC&#41;&#46; El coeficiente alfa de Cronbach de la puntuaci&#243;n total fue de 0&#44;864&#46; Las mujeres con FQ presentan puntuaciones m&#225;s altas que los varones&#44; aunque sin alcanzar la significaci&#243;n estad&#237;stica&#46; Se observa una gradaci&#243;n de las puntuaciones &#40;de forma estad&#237;sticamente significativa&#41; en funci&#243;n de la grave-dad de la afectaci&#243;n pulmonar &#40;a mayor gravedad&#44; peor CV&#41;&#46; Se han encontrado relaciones positivas&#44; estad&#237;sticamente significativas&#44; entre las dimensiones del SGRQ y la edad&#44; el &#237;ndice de masa corporal y el porcentaje de masa grasa&#44; y negativas con el NIH modificado&#44; el Bhalla&#44; el volumen espiratorio forzado en el primer segundo &#40;expresado en porcentaje&#41; y las concentraciones de cinc y somatomedina C&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">Los adultos con FQ tienen peor percepci&#243;n de la CV que la poblaci&#243;n general y que los afectados de EPOC&#46; El SGRQ es v&#225;lido para analizar la CV relacionada con la salud de las personas adultas con FQ&#44; ya que discrimina muy bien entre los distintos grados de gravedad de la funci&#243;n pulmonar y presenta una adecuada consistencia interna&#46;</p>"
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Original Articles
Validity and Reliability of the St George's Respiratory Questionnaire in Adults With Cystic Fibrosis
Alicia Padillaa,
Corresponding author
apadillag@mixmail.com

Correspondence: Dra. A. Padilla. Urbanización Carlinda, bloque 6, 2.º A. 29010 Málaga, España
, Gabriel Olveirab, Casilda Olveiraa, Antonio Doradoa, Antonio J. Platac, Inmaculada Gaspara, Javier Pérez-Fríasd
a Unidad de Fibrosis Quística, Servicio de Neumología, Hospital Regional Universitario Carlos Haya, Málaga, Spain
b Unidad de Fibrosis Quística, Servicio de Endocrinología y Nutrición, Hospital Regional Universitario Carlos Haya, Málaga, Spain
c Servicio de Medicina Interna, Hospital Regional Universitario Carlos Haya, Málaga, Spain
d Unidad de Fibrosis Quística Servicio de Pediatría-Neumología Infantil, Hospital Regional Universitario Carlos Haya, Málaga, Spain
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">To study self-perceived quality of life in adults with cystic fibrosis &#40;CF&#41;&#44; and to assess the validity of the St George&#39;s Respiratory Questionnaire &#40;SGRQ&#41; for use in these patients&#46;</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p class="elsevierStyleSimplePara elsevierViewall">We studied 37 adults with CF who were in stable condition as indicated by their respiratory and nutritional status&#46; Disease severity was assessed by spirometry used in conjunction with a modified National Institutes of Health &#40;NIH&#41; scoring system and the Bhalla scale&#46; Nutritional status was evaluated by measuring height and weight&#44; calculating body mass index&#44; analyzing bioelectric impedance&#44; and performing various laboratory tests&#46; The patients&#39; quality of life was assessed using the SGRQ&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">SGRQ scores were higher &#40;indicating poorer quality of life&#41; among patients with CF than in the general population or among patients with chronic obstructive pulmonary disease&#46; Internal consistency coefficients indicated the SGRQ had good reliability &#40;Cronbach&#39;s alpha&#44; 0&#46;864&#41;&#46; Women with CF tended to score higher than men&#44; although this difference was not statistically significantly&#46; A statistically significant relationship was observed between SGRQ score and severity of pulmonary impairment &#40;the more severe the impairment&#44; the worse the patient&#39;s quality of life&#41;&#46; Statistically significant positive relationships were found between SGRQ domains and age&#44; body mass index&#44; and body fat percentage&#46; Significant negative relationships were found between these domains and the modified NIH score&#44; the Bhalla score&#44; forced expiratory volume in 1 second &#40;expressed as a percentage of predicted&#41;&#44; and somatomedin C and zinc levels&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">Self-perceived quality of life is worse among adults with CF than in the general population or among patients with chronic obstructive pulmonary disease&#46; The SGRQ is a valid instrument for analyzing health-related quality of life in adults with CF as it discriminates very well between different degrees of severity of pulmonary impairment and has acceptable internal consistency&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">Estudiar la percepci&#243;n de la calidad de vida &#40;CV&#41; en una poblaci&#243;n adulta con fibrosis qu&#237;stica &#40;FQ&#41; y valorar la validez del Cuestionario Respiratorio St&#46; George &#40;SGRQ&#41; en estos pacientes&#46;</p> <span class="elsevierStyleSectionTitle">Pacientes y m&#233;todos</span><p class="elsevierStyleSimplePara elsevierViewall">Hemos estudiado a 37 personas adultas con FQ&#44; estables desde el punto de vista respiratorio y nutricional&#46; Se realiz&#243; una valoraci&#243;n de la gravedad de la enfermedad mediante espirometr&#237;a y los sistemas NIH &#40;National Institutes of Health&#41; modificado y Bhalla&#44; as&#237; como una valoraci&#243;n nutricional mediante la medici&#243;n del peso&#44; la talla&#44; el &#237;ndice de masa corporal&#44; impedanciometr&#237;a bioel&#233;ctrica y par&#225;metros anal&#237;ticos&#46; Se estim&#243; la percepci&#243;n de la CV mediante el SGRQ&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Las personas con FQ tienen mayores puntuaciones &#40;peor CV&#41; que la poblaci&#243;n general y que los afectados de enfermedad pulmonar obstructiva cr&#243;nica &#40;EPOC&#41;&#46; El coeficiente alfa de Cronbach de la puntuaci&#243;n total fue de 0&#44;864&#46; Las mujeres con FQ presentan puntuaciones m&#225;s altas que los varones&#44; aunque sin alcanzar la significaci&#243;n estad&#237;stica&#46; Se observa una gradaci&#243;n de las puntuaciones &#40;de forma estad&#237;sticamente significativa&#41; en funci&#243;n de la grave-dad de la afectaci&#243;n pulmonar &#40;a mayor gravedad&#44; peor CV&#41;&#46; Se han encontrado relaciones positivas&#44; estad&#237;sticamente significativas&#44; entre las dimensiones del SGRQ y la edad&#44; el &#237;ndice de masa corporal y el porcentaje de masa grasa&#44; y negativas con el NIH modificado&#44; el Bhalla&#44; el volumen espiratorio forzado en el primer segundo &#40;expresado en porcentaje&#41; y las concentraciones de cinc y somatomedina C&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">Los adultos con FQ tienen peor percepci&#243;n de la CV que la poblaci&#243;n general y que los afectados de EPOC&#46; El SGRQ es v&#225;lido para analizar la CV relacionada con la salud de las personas adultas con FQ&#44; ya que discrimina muy bien entre los distintos grados de gravedad de la funci&#243;n pulmonar y presenta una adecuada consistencia interna&#46;</p>"
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ISSN: 15792129
Original language: English
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