Correspondence: Dra. A. Padilla. Urbanización Carlinda, bloque 6, 2.º A. 29010 Málaga, España
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Plata, Inmaculada Gaspar, Javier Pérez-Frías" "autores" => array:7 [ 0 => array:4 [ "nombre" => "Alicia" "apellidos" => "Padilla" "email" => array:1 [ 0 => "apadillag@mixmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor1" ] ] ] 1 => array:3 [ "nombre" => "Gabriel" "apellidos" => "Olveira" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] ] 2 => array:3 [ "nombre" => "Casilda" "apellidos" => "Olveira" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 3 => array:3 [ "nombre" => "Antonio" "apellidos" => "Dorado" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 4 => array:3 [ "nombre" => "Antonio J." "apellidos" => "Plata" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff3" ] ] ] 5 => array:3 [ "nombre" => "Inmaculada" "apellidos" => "Gaspar" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 6 => array:3 [ "nombre" => "Javier" "apellidos" => "Pérez-Frías" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">d</span>" "identificador" => "aff4" ] ] ] ] "afiliaciones" => array:4 [ 0 => array:3 [ "entidad" => "Unidad de Fibrosis Quística, Servicio de Neumología, Hospital Regional Universitario Carlos Haya, Málaga, Spain" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:3 [ "entidad" => "Unidad de Fibrosis Quística, Servicio de Endocrinología y Nutrición, Hospital Regional Universitario Carlos Haya, Málaga, Spain" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] 2 => array:3 [ "entidad" => "Servicio de Medicina Interna, Hospital Regional Universitario Carlos Haya, Málaga, Spain" "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff3" ] 3 => array:3 [ "entidad" => "Unidad de Fibrosis Quística Servicio de Pediatría-Neumología Infantil, Hospital Regional Universitario Carlos Haya, Málaga, Spain" "etiqueta" => "<span class="elsevierStyleSup">d</span>" "identificador" => "aff4" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "*" "correspondencia" => "Correspondence: Dra. A. Padilla. Urbanización Carlinda, bloque 6, 2.º A. 29010 Málaga, España" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2005-12-06" "fechaAceptado" => "2006-10-31" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec154839" "palabras" => array:3 [ 0 => "Cystic fibrosis" 1 => "Quality of life" 2 => "St George's Respiratory Questionnaire" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec154840" "palabras" => array:3 [ 0 => "Fibrosis quística" 1 => "Calidad de vida" 2 => "Cuestionario St George (SGRQ)" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">To study self-perceived quality of life in adults with cystic fibrosis (CF), and to assess the validity of the St George's Respiratory Questionnaire (SGRQ) for use in these patients.</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p class="elsevierStyleSimplePara elsevierViewall">We studied 37 adults with CF who were in stable condition as indicated by their respiratory and nutritional status. Disease severity was assessed by spirometry used in conjunction with a modified National Institutes of Health (NIH) scoring system and the Bhalla scale. Nutritional status was evaluated by measuring height and weight, calculating body mass index, analyzing bioelectric impedance, and performing various laboratory tests. The patients' quality of life was assessed using the SGRQ.</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">SGRQ scores were higher (indicating poorer quality of life) among patients with CF than in the general population or among patients with chronic obstructive pulmonary disease. Internal consistency coefficients indicated the SGRQ had good reliability (Cronbach's alpha, 0.864). Women with CF tended to score higher than men, although this difference was not statistically significantly. A statistically significant relationship was observed between SGRQ score and severity of pulmonary impairment (the more severe the impairment, the worse the patient's quality of life). Statistically significant positive relationships were found between SGRQ domains and age, body mass index, and body fat percentage. Significant negative relationships were found between these domains and the modified NIH score, the Bhalla score, forced expiratory volume in 1 second (expressed as a percentage of predicted), and somatomedin C and zinc levels.</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">Self-perceived quality of life is worse among adults with CF than in the general population or among patients with chronic obstructive pulmonary disease. The SGRQ is a valid instrument for analyzing health-related quality of life in adults with CF as it discriminates very well between different degrees of severity of pulmonary impairment and has acceptable internal consistency.</p>" ] "es" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">Estudiar la percepción de la calidad de vida (CV) en una población adulta con fibrosis quística (FQ) y valorar la validez del Cuestionario Respiratorio St. George (SGRQ) en estos pacientes.</p> <span class="elsevierStyleSectionTitle">Pacientes y métodos</span><p class="elsevierStyleSimplePara elsevierViewall">Hemos estudiado a 37 personas adultas con FQ, estables desde el punto de vista respiratorio y nutricional. Se realizó una valoración de la gravedad de la enfermedad mediante espirometría y los sistemas NIH (National Institutes of Health) modificado y Bhalla, así como una valoración nutricional mediante la medición del peso, la talla, el índice de masa corporal, impedanciometría bioeléctrica y parámetros analíticos. Se estimó la percepción de la CV mediante el SGRQ.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Las personas con FQ tienen mayores puntuaciones (peor CV) que la población general y que los afectados de enfermedad pulmonar obstructiva crónica (EPOC). El coeficiente alfa de Cronbach de la puntuación total fue de 0,864. Las mujeres con FQ presentan puntuaciones más altas que los varones, aunque sin alcanzar la significación estadística. Se observa una gradación de las puntuaciones (de forma estadísticamente significativa) en función de la grave-dad de la afectación pulmonar (a mayor gravedad, peor CV). Se han encontrado relaciones positivas, estadísticamente significativas, entre las dimensiones del SGRQ y la edad, el índice de masa corporal y el porcentaje de masa grasa, y negativas con el NIH modificado, el Bhalla, el volumen espiratorio forzado en el primer segundo (expresado en porcentaje) y las concentraciones de cinc y somatomedina C.</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">Los adultos con FQ tienen peor percepción de la CV que la población general y que los afectados de EPOC. El SGRQ es válido para analizar la CV relacionada con la salud de las personas adultas con FQ, ya que discrimina muy bien entre los distintos grados de gravedad de la función pulmonar y presenta una adecuada consistencia interna.</p>" ] ] "NotaPie" => array:1 [ 0 => array:1 [ "nota" => "<p class="elsevierStyleNotepara">This study was partially financed with a grant from the health department of the autonomous community of Andalusia (Consejería de la Salud de la Junta de Andalucía 02/150) and by the Spanish Ministry of Health and Consumer Affairs (Ministerio de Sanidad y Consumo, Instituto de Salud Carlos III, Red R006/0015/0008).</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:28 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Identification of the cystic fibrosis gene: genetic analysis" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "BS Kerem" 1 => "JM Rommens" 2 => "JA Buchanan" 3 => "D Markiewicz" 4 => "TK Cox" 5 => "A Chakravarti" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Science" "fecha" => "1989" "volumen" => "245" "paginaInicial" => "1073" "paginaFinal" => "1080" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2570460" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Fibrosis quística" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "MT Martínez" 1 => "G García" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Arch Bronconeumol" "fecha" => "2000" "volumen" => "36" "numero" => "Supl 4" "paginaInicial" => "13" "paginaFinal" => "20" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10726179" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib3" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Tratamiento antimicrobiano frente a la colonización pulmonar por Pseudomonas aeruginosa en el paciente con fibrosis quística" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "R Cantón" 1 => "N Cobos" 2 => "J de Gracia" 3 => "F Baquero" 4 => "J Honorato" 5 => "S Gartner" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Bronconeumol" "fecha" => "2005" "volumen" => "41" "numero" => "Supl 1" "paginaInicial" => "1" "paginaFinal" => "25" ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib4" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cystic fibrosis. 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Year/Month | Html | Total | |
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2024 November | 2 | 2 | 4 |
2024 October | 56 | 15 | 71 |
2024 September | 45 | 23 | 68 |
2024 August | 72 | 40 | 112 |
2024 July | 30 | 27 | 57 |
2024 June | 33 | 31 | 64 |
2024 May | 47 | 31 | 78 |
2024 April | 20 | 28 | 48 |
2024 March | 17 | 14 | 31 |
2024 February | 25 | 22 | 47 |
2023 March | 2 | 1 | 3 |
2023 February | 18 | 19 | 37 |
2023 January | 21 | 29 | 50 |
2022 December | 20 | 21 | 41 |
2022 November | 13 | 22 | 35 |
2022 October | 22 | 35 | 57 |
2022 September | 15 | 20 | 35 |
2022 August | 18 | 34 | 52 |
2022 July | 16 | 33 | 49 |
2022 June | 22 | 37 | 59 |
2022 May | 18 | 25 | 43 |
2022 April | 22 | 30 | 52 |
2022 March | 17 | 35 | 52 |
2022 February | 18 | 24 | 42 |
2022 January | 11 | 27 | 38 |
2021 December | 16 | 49 | 65 |
2021 November | 11 | 45 | 56 |
2021 October | 18 | 32 | 50 |
2021 September | 18 | 55 | 73 |
2021 August | 15 | 29 | 44 |
2021 July | 21 | 26 | 47 |
2021 June | 18 | 25 | 43 |
2021 May | 26 | 33 | 59 |
2021 April | 42 | 23 | 65 |
2021 March | 19 | 28 | 47 |
2021 February | 22 | 16 | 38 |
2021 January | 15 | 20 | 35 |
2020 December | 18 | 18 | 36 |
2020 November | 15 | 9 | 24 |
2020 October | 11 | 10 | 21 |
2020 September | 6 | 7 | 13 |
2020 August | 9 | 9 | 18 |
2020 July | 11 | 16 | 27 |
2020 June | 8 | 8 | 16 |
2020 May | 8 | 15 | 23 |
2020 April | 9 | 10 | 19 |
2020 March | 5 | 12 | 17 |
2020 February | 7 | 20 | 27 |
2020 January | 15 | 15 | 30 |
2019 December | 14 | 14 | 28 |
2019 November | 12 | 2 | 14 |
2019 October | 5 | 10 | 15 |
2019 September | 9 | 8 | 17 |
2019 August | 13 | 6 | 19 |
2019 July | 12 | 12 | 24 |
2019 June | 4 | 16 | 20 |
2019 May | 10 | 15 | 25 |
2019 April | 16 | 26 | 42 |
2019 March | 17 | 22 | 39 |
2019 February | 14 | 10 | 24 |
2019 January | 13 | 14 | 27 |
2018 December | 9 | 8 | 17 |
2018 November | 12 | 14 | 26 |
2018 October | 14 | 17 | 31 |
2018 September | 13 | 9 | 22 |
2018 May | 2 | 0 | 2 |
2018 April | 10 | 6 | 16 |
2018 March | 14 | 5 | 19 |
2018 February | 9 | 7 | 16 |
2018 January | 3 | 4 | 7 |
2017 December | 2 | 7 | 9 |
2017 November | 3 | 20 | 23 |
2017 October | 3 | 19 | 22 |
2017 September | 2 | 16 | 18 |
2017 August | 5 | 27 | 32 |
2017 July | 4 | 14 | 18 |
2017 June | 8 | 29 | 37 |
2017 May | 6 | 17 | 23 |
2017 April | 1 | 10 | 11 |
2017 March | 1 | 7 | 8 |
2017 February | 3 | 12 | 15 |
2017 January | 2 | 8 | 10 |
2016 December | 3 | 10 | 13 |
2016 November | 18 | 8 | 26 |
2016 October | 21 | 5 | 26 |
2016 September | 14 | 13 | 27 |
2016 August | 15 | 6 | 21 |
2016 July | 8 | 5 | 13 |
2016 March | 1 | 0 | 1 |
2016 February | 1 | 0 | 1 |
2015 December | 2 | 0 | 2 |
2015 October | 58 | 10 | 68 |
2015 September | 72 | 12 | 84 |
2015 August | 53 | 6 | 59 |
2015 July | 51 | 7 | 58 |
2015 June | 40 | 7 | 47 |
2015 May | 60 | 9 | 69 |
2015 April | 52 | 13 | 65 |
2015 March | 42 | 7 | 49 |
2015 February | 33 | 4 | 37 |
2015 January | 45 | 8 | 53 |
2014 December | 44 | 4 | 48 |
2014 November | 63 | 9 | 72 |
2014 October | 83 | 7 | 90 |
2014 September | 52 | 5 | 57 |
2014 August | 53 | 9 | 62 |
2014 July | 54 | 10 | 64 |
2014 June | 52 | 9 | 61 |
2014 May | 55 | 10 | 65 |
2014 April | 77 | 7 | 84 |
2014 March | 52 | 9 | 61 |
2014 February | 65 | 11 | 76 |
2014 January | 48 | 6 | 54 |
2013 December | 57 | 12 | 69 |
2013 November | 59 | 7 | 66 |
2013 October | 51 | 10 | 61 |
2013 September | 58 | 8 | 66 |
2013 August | 45 | 7 | 52 |
2013 July | 71 | 14 | 85 |
2013 June | 34 | 10 | 44 |
2013 May | 55 | 9 | 64 |
2013 April | 18 | 5 | 23 |
2013 March | 15 | 3 | 18 |