Techniques And Procedures
Measurement of Fraction of Exhaled Nitric Oxide With the Portable NIOX-MINO Monitor in Healthy Adult
Ana María Fortuna, Teresa Feixas, Pere Casan
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pcasan@hsp.santpau.es
Correspondence: Dr. P. Casan. Unidad de Función Pulmonar. Hospital de la Santa Creu i Sant Pau. St. Antoni M. Claret, 167. 08025 Barcelona. España
Correspondence: Dr. P. Casan. Unidad de Función Pulmonar. Hospital de la Santa Creu i Sant Pau. St. Antoni M. Claret, 167. 08025 Barcelona. España
Unidad de Función Pulmonar, Departamento de Neumología, Hospital de la Santa Creu i Sant Pau. Facultad de Medicina, Universidad Autónoma de Barcelona, Barcelona, Spain
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"apellidos" => "Castro-Rodríguez" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1579212907600433?idApp=UINPBA00003Z" "url" => "/15792129/0000004300000003/v1_201305150311/S1579212907600433/v1_201305150311/en/main.assets" ] "en" => array:14 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Techniques And Procedures</span>" "titulo" => "Measurement of Fraction of Exhaled Nitric Oxide With the Portable NIOX-MINO Monitor in Healthy Adult" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "176" "paginaFinal" => "179" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Ana María Fortuna, Teresa Feixas, Pere Casan" "autores" => array:3 [ 0 => array:2 [ "nombre" => "Ana María" "apellidos" => "Fortuna" ] 1 => array:2 [ "nombre" => "Teresa" "apellidos" => "Feixas" ] 2 => array:4 [ "nombre" => "Pere" "apellidos" => "Casan" "email" => array:1 [ 0 => "pcasan@hsp.santpau.es" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor1" ] ] ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Unidad de Función Pulmonar, Departamento de Neumología, Hospital de la Santa Creu i Sant Pau. Facultad de Medicina, Universidad Autónoma de Barcelona, Barcelona, Spain" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "*" "correspondencia" => "Correspondence: Dr. P. Casan. Unidad de Función Pulmonar. Hospital de la Santa Creu i Sant Pau. St. Antoni M. Claret, 167. 08025 Barcelona. España" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2006-03-14" "fechaAceptado" => "2006-05-21" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec154815" "palabras" => array:3 [ 0 => "Fraction of exhaled nitric oxide" 1 => "Asthma" 2 => "Inflammation" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec154814" "palabras" => array:3 [ 0 => "Óxido nítrico en aire espirado" 1 => "Asma" 2 => "Inflamación" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:1 [ "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">Measurement of the fraction of exhaled nitric oxide (FE<span class="elsevierStyleInf">NO</span>) provides a noninvasive way to monitor asthma treatment in clinical practice. The aim of this study was to determine FE<span class="elsevierStyleInf">NO</span> reference values for measurements recorded with the portable NIOX MINO monitor in a group of healthy volunteers. We also assessed the association between values recorded by the portable monitor and the N-6008 chemiluminescence analyzer used in our pulmonary function laboratory. The FE<span class="elsevierStyleInf">NO</span> values obtained with the portable monitor were consistently higher than those recorded by the N-6008 monitor; the cutoff value for the portable monitor was 34 ppb (mean + 2 SD). We detected a direct correlation (r=0.92) between the FE<span class="elsevierStyleInf">NO</span> measurements recorded by the 2 monitors (P=.001). The following equation expresses the relationship between measurements from the 2 devices: FE<span class="elsevierStyleInf">NO</span>(NIOX-MINO) = 10 + [1.5 FE<span class="elsevierStyleInf">NO</span>(N-6008)]. We did not observe statistically significant correlations between FE<span class="elsevierStyleInf">NO</span> measurements and age, sex, body mass index, or spirometry.</p>" ] "es" => array:1 [ "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">La determinación de óxido nítrico en aire espirado (FE<span class="elsevierStyleInf">NO</span>) es una técnica no invasiva que se utiliza en la evaluación clínica y el tratamiento del asma. El objetivo de este estudio ha sido determinar los valores de referencia de FE<span class="elsevierStyleInf">NO</span> en un grupo de voluntarios sanos mediante la utilización de un nuevo equipo portátil (NIOX-MINO® Aerocrine), así como determinar el grado de relación que presenta con el equipo de determinación habitual en nuestro laboratorio de función pulmonar (sensor de quimioluminiscencia N-6008® SIR). Según los resultados obtenidos, los valores de FE<span class="elsevierStyleInf">NO</span> que da el equipo portátil son siempre superiores a los que ofrece el sensor habitual, con un valor de corte de 34 ppb (media + 2 desviación estándar). Existe un relación directa y significativa de la determinación de FE<span class="elsevierStyleInf">NO</span> entre ambos equipos (r = 0,92; p = 0,001) con un factor de corrección de: FE<span class="elsevierStyleInf">NO</span> (NIOX-MINO®) = 10 + 1,5 FE<span class="elsevierStyleInf">NO</span> (N-6008®). La relación entre los valores de FE<span class="elsevierStyleInf">NO</span> y la edad, el sexo, el índice de masa corporal y los valores espirométricos no fue estadísticamente significativa.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "REFERENCES" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:13 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Global Strategy for Asthma Management and Prevention NHLBI/WHO Workshop Report 2002" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "Global Initiative for Asthma" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "WWW" => array:1 [ "link" => "Available from: http://www.ginasthma.com" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Correlation between exhaled 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| 2015 March | 68 | 24 | 92 |
| 2015 February | 71 | 10 | 81 |
| 2015 January | 93 | 21 | 114 |
| 2014 December | 78 | 15 | 93 |
| 2014 November | 107 | 20 | 127 |
| 2014 October | 120 | 38 | 158 |
| 2014 September | 78 | 11 | 89 |
| 2014 August | 78 | 22 | 100 |
| 2014 July | 86 | 17 | 103 |
| 2014 June | 87 | 17 | 104 |
| 2014 May | 95 | 20 | 115 |
| 2014 April | 98 | 15 | 113 |
| 2014 March | 95 | 21 | 116 |
| 2014 February | 88 | 21 | 109 |
| 2014 January | 100 | 18 | 118 |
| 2013 December | 67 | 17 | 84 |
| 2013 November | 78 | 14 | 92 |
| 2013 October | 73 | 34 | 107 |
| 2013 September | 80 | 14 | 94 |
| 2013 August | 78 | 26 | 104 |
| 2013 July | 81 | 22 | 103 |
| 2013 June | 60 | 18 | 78 |
| 2013 May | 46 | 19 | 65 |
| 2013 April | 57 | 21 | 78 |
| 2013 March | 11 | 7 | 18 |
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