Correspondence: Dr. J.L. Duque. Servicio de Cirugía Torácica. Hospital Universitario de Valladolid. Avda. Ramón y Cajal, 3. 47003 Valladolid. España
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Duque. Servicio de Cirugía Torácica. Hospital Universitario de Valladolid. Avda. Ramón y Cajal, 3. 47003 Valladolid. España" ] ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2006-01-09" "fechaAceptado" => "2006-09-19" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec154792" "palabras" => array:4 [ 0 => "Bronchogenic carcinoma" 1 => "Risk factors" 2 => "Morbidity" 3 => "Mortality" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec154791" "palabras" => array:4 [ 0 => "Carcinoma broncogénico" 1 => "Parámetros de riesgo" 2 => "Morbilidad" 3 => "Mortalidad" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p class="elsevierStyleSimplePara elsevierViewall">To analyze the factors that determine the risk of morbidity and mortality associated with lung resection in patients with bronchogenic carcinoma.</p> <span class="elsevierStyleSectionTitle">Patients and Methods</span><p class="elsevierStyleSimplePara elsevierViewall">Prospective multicenter study conducted between October 1, 1993 and September 30, 1997 in the 19 hospitals that make up the Bronchogenic Carcinoma Cooperative Group. During the study period, 2994 patients with bronchogenic carcinoma underwent surgery. The morbidity and mortality data at 30 days from all centers were recorded in a single registry.</p> <span class="elsevierStyleSectionTitle">Results</span><p class="elsevierStyleSimplePara elsevierViewall">Major resection was performed in 2491 patients, whereas 212 underwent minor resection. The resection had to be extended in 296 and exploratory thoracotomy was carried out in 291.</p><p class="elsevierStyleSimplePara elsevierViewall">Postoperative complications were reported in 1057 patients(35.2%). Complications directly related to surgery were the most common (22.9%), followed by respiratory (19.5%) and cardiovascular (10.7%) complications. Of the patients with complications, 654 patients (21.8%) had only 1, whereas 403(13.4%) had more than 1. After classification of complications, 21% were found to be minor and 14.2% were major.</p><p class="elsevierStyleSimplePara elsevierViewall">Mortality at 30 days was 6.8% (204 patients), and strongly linked to the presentation of major complications—40.8% of those with such complications died.</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p class="elsevierStyleSimplePara elsevierViewall">Surgical treatment of bronchogenic carcinoma in Spain is associated with high morbidity and mortality. The morbidity reported in the present study lies in the middle of the ranges found in the literature, whereas mortality lies at the high end of the range. The presence of major complications and/or multiple complications should be considered as strong risk factors.</p>" ] "es" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p class="elsevierStyleSimplePara elsevierViewall">Analizar la morbilidad y mortalidad asociadas a la cirugía de exéresis pulmonar por carcinoma broncogénico, como parámetros definitorios del riesgo inherente a este tratamiento.</p> <span class="elsevierStyleSectionTitle">Pacientes y Métodos</span><p class="elsevierStyleSimplePara elsevierViewall">Estudio prospectivo y multicéntrico, realizado en los 19 hospitales integrantes del Grupo Cooperativo de Carcinoma Broncogénico entre el 1 de octubre de 1993 y el 30 de septiembre de 1997. En este tiempo fueron sometidos a toracotomía 2.994 pacientes con carcinoma broncogénico. La morbilidad y mortalidad a los 30 días se recogieron mediante un registro de datos unificado para todos los hospitales.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p class="elsevierStyleSimplePara elsevierViewall">Se practicaron 2.491 exéresis mayores y 212 menores. Se precisó resección extendida en 296 pacientes, mientras que en 291 se efectuó toracotomía exploradora.</p><p class="elsevierStyleSimplePara elsevierViewall">En 1.057 pacientes (35,2%) se objetivaron complicaciones postoperatorias, de las que las más frecuentes fueron las relacionadas directamente con la intervención quirúrgica (22,9%), seguidas por las respiratorias (19,5%) y las cardiovasculares (10,7%). En 654 casos (21,8%) las complicaciones fueron de carácter único, mientras que 403 (13,4%) presentaron más de una. Atendiendo a su categoría, el 21% de las complicaciones fueron menores, en tanto que las complicaciones mayores sucedieron en el 14,2% de los casos.</p><p class="elsevierStyleSimplePara elsevierViewall">El análisis de la mortalidad en los 30 primeros días mostró una incidencia del 6,8% (204 pacientes), y estuvo notablemente vinculada con la aparición de complicaciones mayores (40,8%).</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p class="elsevierStyleSimplePara elsevierViewall">En nuestro medio el tratamiento quirúrgico del carcinoma broncogénico genera una morbilidad y una mortalidad elevadas, en el rango de las habitualmente referidas en relación con la morbilidad y en el límite alto cuando se considera la mortalidad. La presencia de complicaciones mayores y/o su multiplicidad deben considerarse elementos sustancialmente moduladores del incremento del riesgo.</p>" ] ] "NotaPie" => array:2 [ 0 => array:3 [ "etiqueta" => "1" "nota" => "<p class="elsevierStyleNotepara">The coordinators and members of the GCCB-S are listed at the end of the article.</p>" "identificador" => "fn1" ] 1 => array:1 [ "nota" => "<p class="elsevierStyleNotepara">This study was partially funded by the grants FIS97/0011 and FEPAR-1995. Additional financial support was provided by the government (Junta) of the autonomous community of Castile-Leon and the Menarini Foundation.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "REFERENCES" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:32 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lung cancer guidelines. 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Year/Month | Html | Total | |
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2024 November | 4 | 4 | 8 |
2024 October | 35 | 29 | 64 |
2024 September | 34 | 16 | 50 |
2024 August | 61 | 37 | 98 |
2024 July | 27 | 20 | 47 |
2024 June | 30 | 28 | 58 |
2024 May | 32 | 24 | 56 |
2024 April | 32 | 30 | 62 |
2024 March | 25 | 21 | 46 |
2024 February | 22 | 30 | 52 |
2023 March | 4 | 3 | 7 |
2023 February | 16 | 21 | 37 |
2023 January | 18 | 36 | 54 |
2022 December | 24 | 30 | 54 |
2022 November | 28 | 37 | 65 |
2022 October | 30 | 49 | 79 |
2022 September | 23 | 31 | 54 |
2022 August | 24 | 35 | 59 |
2022 July | 36 | 45 | 81 |
2022 June | 27 | 33 | 60 |
2022 May | 20 | 37 | 57 |
2022 April | 24 | 31 | 55 |
2022 March | 30 | 60 | 90 |
2022 February | 17 | 38 | 55 |
2022 January | 15 | 35 | 50 |
2021 December | 13 | 42 | 55 |
2021 November | 13 | 39 | 52 |
2021 October | 26 | 45 | 71 |
2021 September | 19 | 52 | 71 |
2021 August | 9 | 35 | 44 |
2021 July | 8 | 24 | 32 |
2021 June | 8 | 30 | 38 |
2021 May | 12 | 33 | 45 |
2021 April | 34 | 29 | 63 |
2021 March | 19 | 22 | 41 |
2021 February | 8 | 10 | 18 |
2021 January | 9 | 15 | 24 |
2020 December | 7 | 6 | 13 |
2020 November | 5 | 4 | 9 |
2020 October | 2 | 3 | 5 |
2020 September | 4 | 7 | 11 |
2020 August | 5 | 7 | 12 |
2020 July | 16 | 11 | 27 |
2020 June | 14 | 4 | 18 |
2020 May | 16 | 12 | 28 |
2020 April | 14 | 14 | 28 |
2020 March | 18 | 10 | 28 |
2020 February | 11 | 13 | 24 |
2020 January | 14 | 17 | 31 |
2019 December | 11 | 13 | 24 |
2019 November | 11 | 5 | 16 |
2019 October | 4 | 4 | 8 |
2019 September | 9 | 19 | 28 |
2019 August | 12 | 2 | 14 |
2019 July | 11 | 22 | 33 |
2019 June | 7 | 12 | 19 |
2019 May | 11 | 11 | 22 |
2019 April | 20 | 15 | 35 |
2019 March | 13 | 13 | 26 |
2019 February | 12 | 13 | 25 |
2019 January | 8 | 11 | 19 |
2018 December | 11 | 7 | 18 |
2018 November | 11 | 6 | 17 |
2018 October | 24 | 13 | 37 |
2018 September | 12 | 11 | 23 |
2018 May | 3 | 0 | 3 |
2018 April | 5 | 6 | 11 |
2018 March | 6 | 5 | 11 |
2018 February | 9 | 7 | 16 |
2018 January | 5 | 8 | 13 |
2017 December | 8 | 6 | 14 |
2017 November | 12 | 8 | 20 |
2017 October | 7 | 7 | 14 |
2017 September | 11 | 6 | 17 |
2017 August | 13 | 9 | 22 |
2017 July | 8 | 4 | 12 |
2017 June | 21 | 11 | 32 |
2017 May | 8 | 5 | 13 |
2017 April | 5 | 1 | 6 |
2017 March | 24 | 6 | 30 |
2017 February | 2 | 1 | 3 |
2017 January | 1 | 0 | 1 |
2016 December | 2 | 6 | 8 |
2016 November | 10 | 7 | 17 |
2016 October | 12 | 4 | 16 |
2016 September | 10 | 5 | 15 |
2016 August | 11 | 4 | 15 |
2016 July | 6 | 3 | 9 |
2016 March | 1 | 0 | 1 |
2016 February | 1 | 0 | 1 |
2015 December | 2 | 0 | 2 |
2015 October | 59 | 7 | 66 |
2015 September | 63 | 6 | 69 |
2015 August | 39 | 11 | 50 |
2015 July | 48 | 4 | 52 |
2015 June | 35 | 4 | 39 |
2015 May | 50 | 5 | 55 |
2015 April | 44 | 7 | 51 |
2015 March | 60 | 7 | 67 |
2015 February | 50 | 4 | 54 |
2015 January | 59 | 6 | 65 |
2014 December | 58 | 4 | 62 |
2014 November | 67 | 4 | 71 |
2014 October | 63 | 7 | 70 |
2014 September | 51 | 5 | 56 |
2014 August | 53 | 10 | 63 |
2014 July | 41 | 6 | 47 |
2014 June | 45 | 7 | 52 |
2014 May | 57 | 12 | 69 |
2014 April | 48 | 5 | 53 |
2014 March | 55 | 12 | 67 |
2014 February | 43 | 13 | 56 |
2014 January | 45 | 9 | 54 |
2013 December | 34 | 11 | 45 |
2013 November | 39 | 7 | 46 |
2013 October | 37 | 4 | 41 |
2013 September | 38 | 9 | 47 |
2013 August | 34 | 6 | 40 |
2013 July | 50 | 10 | 60 |
2013 June | 37 | 6 | 43 |
2013 May | 31 | 4 | 35 |
2013 April | 18 | 2 | 20 |
2013 March | 6 | 1 | 7 |